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Living donor liver transplantation

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https://www.readbyqxmd.com/read/28078819/live-donor-liver-transplantation-for-a-child-presented-with-severe-hepatopulmonary-syndrome-and-nodular-liver-lesions-due-to-abernethy-malformation
#1
Cahit Yilmaz, Zafer Onen, Rasim Farajov, Onur S Duygu, Latife Doganay, Alper Yuksel, Mehmet Alper, Murat Zeytunlu, Cigdem Arikan, Murat Kilic
A 15-year-old boy first presented with severe lung lesions and hypoxia and he was considered as a lung transplant candidate. Upon evaluation, hepatopulmonary syndrome, multiple nodular liver lesions, and Abernethy type 1b malformation were diagnosed. The patient underwent successful right lobe live donor liver transplantation, and all of the symptoms disappeared soon after the transplant. He is currently alive and well with excellent liver and lung functions 4 years after surgery.
January 12, 2017: Pediatric Transplantation
https://www.readbyqxmd.com/read/28073180/porto-systemic-collaterals-in-living-donor-liver-transplantation-what-s-all-the-fuss-about
#2
REVIEW
Mettu Srinivas Reddy, Mohamed Rela
Porto-systemic collaterals are a common finding in patients with cirrhosis undergoing liver transplantation. Recently, there has been renewed interest regarding their significance in the setting of living donor liver transplantation (LDLT) due to concerns of graft hypo or hyper-perfusion and its impact on early post-transplant outcomes. Presence of these collaterals has greater significance in the LDLT setting when compared to deceased donor liver transplant setting as dictated by the difference in the physiology of partial liver grafts...
January 10, 2017: Liver Transplantation
https://www.readbyqxmd.com/read/28073174/successful-application-of-supra-coeliac-aorto-hepatic-conduit-using-saphenous-venous-graft-in-right-lobe-living-donor-liver-transplantation
#3
Ping-Chun Li, Ashok Thorat, Long-Bin Jeng, Horng-Ren Yang, Ming-Li Li, Chun-Chieh Yeh, Te-Hung Chen, Shih-Chao Hsu, Kin-Shing Poon
No abstract text is available yet for this article.
January 10, 2017: Liver Transplantation
https://www.readbyqxmd.com/read/28073169/vascular-complication-rates-in-living-donor-liver-transplantation-how-low-can-we-go
#4
EDITORIAL
Chris E Freise
No abstract text is available yet for this article.
January 10, 2017: Liver Transplantation
https://www.readbyqxmd.com/read/28072754/initial-outcomes-of-pure-laparoscopic-living-donor-right-hepatectomy-in-an-experienced-adult-living-donor-liver-transplant-center
#5
Ki-Hun Kim, Sung-Hwa Kang, Dong-Hwan Jung, Young-In Yoon, Wan-Joon Kim, Min-Ho Shin, Sung-Gyu Lee
BACKGROUND: Only a limited number of centers have performed laparoscopic living donor hepatectomy to date. In particular, laparoscopic right hepatectomy is rarely performed because the procedure can only be performed by surgeons with significant experience in both laparoscopic liver surgery and liver transplantation with living donor liver grafts. METHODS: Between November 2014 and February 2015, in a pure laparoscopic approach program for living right lobe donors at Asan Medical Center, 92 living donors underwent right hepatectomy for adult living donor liver transplantation (LDLT)...
January 9, 2017: Transplantation
https://www.readbyqxmd.com/read/28066854/live-donor-liver-transplantation-for-antitubercular-drug-induced-acute-liver-failure
#6
Akshay P Bavikatte, S Sudhindran, Puneet Dhar, O V Sudheer, G Unnikrishnan, Dinesh Balakrishnan, Ramachandran N Menon
Antitubercular therapy (ATT)-induced hepatotoxicity is often over looked and active tuberculosis is considered a contraindication for liver transplantation, however it might be the only lifesaving option to certain patients of acute liver failure (ALF) due to ATT. We have assessed the outcome of live donor liver transplantation in ATT-induced ALF. A retrospective analysis of all the cases of ALF that underwent liver transplantation from 2006 to 2014 at the Amrita Institute of Medical Sciences was done. A total of seven (7...
January 9, 2017: Indian Journal of Gastroenterology: Official Journal of the Indian Society of Gastroenterology
https://www.readbyqxmd.com/read/28059833/pushing-the-limits-of-live-donor-liver-transplantation-is-the-western-world-ready-for-dual-grafts
#7
Gonzalo Sapisochin, Nicolas Goldaracena, David R Grant
No abstract text is available yet for this article.
January 4, 2017: Annals of Surgery
https://www.readbyqxmd.com/read/28058211/organ-transplantation-and-drug-eluting-stents-perioperative-challenges
#8
REVIEW
Aparna Dalal
Patients listed for organ transplant frequently have severe coronary artery disease (CAD), which may be treated with drug eluting stents (DES). Everolimus and zotarolimus eluting stents are commonly used. Newer generation biolimus and novolimus eluting biodegradable stents are becoming increasingly popular. Patients undergoing transplant surgery soon after the placement of DES are at increased risk of stent thrombosis (ST) in the perioperative period. Dual antiplatelet therapy (DAPT) with aspirin and a P2Y12 inhibitor such as clopidogrel, prasugrel and ticagrelor is instated post stenting to decrease the incident of ST...
December 24, 2016: World Journal of Transplantation
https://www.readbyqxmd.com/read/28054388/good-outcome-of-living-donor-liver-transplantation-in-drug-induced-acute-liver-failure-a-single-centre-experience
#9
Narendra Singh Choudhary, Sanjiv Saigal, Neeraj Saraf, Amit Rastogi, Sanjay Goja, Prashant Bhangui, Vijay Vohra, Deepak Govil, Arvinder S Soin
INTRODUCTION: Drug induced acute liver failure (ALF) is associated with high mortality. There is limited literature on results of living donor liver transplantation (LDLT). MATERIAL AND METHODS: The study was conducted at a tertiary care centre in North India. All patients who received LDLT for drug induced ALF were included. The data is shown as median (IQR). RESULTS: A total of 18 patients (15 females and 3 males), aged 34(25-45) years, underwent LDLT for DILI related ALF...
January 5, 2017: Clinical Transplantation
https://www.readbyqxmd.com/read/28053342/liver-transplantation-for-hepatocellular-carcinoma-outcomes-and-novel-surgical-approaches
#10
REVIEW
Gonzalo Sapisochin, Jordi Bruix
Liver transplantation for hepatocellular carcinoma (HCC) is the best treatment option for patients with early-stage tumours and accounts for ∼20-40% of all liver transplantations performed at most centres worldwide. The Milan criteria are the most common criteria to select patients with HCC for transplantation but they can be seen as too restrictive. Several proposals have been made for a moderate expansion of the criteria, which result in good outcomes but with an increase in the risk of tumour recurrence...
January 5, 2017: Nature Reviews. Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/28053303/management-of-liver-allograft-trauma-resulting-in-massive-subcapsular-hematoma-after-living-donor-liver-transplantation-can-we-salvage-the-liver-allograft
#11
Shih-Chao Hsu, Ashok Thorat, Kin-Shing Poon, Chun-Chieh Yeh, Te-Hung Chen, Horng-Ren Yang, Long-Bin Jeng
BACKGROUND Liver allograft trauma resulting in subcapsular hematoma after living donor liver transplantation (LDLT), although rare, is a life-threatening condition and requires prompt management to avoid any catastrophe. Herein we describe our successful experience in dealing with liver allograft hematoma that developed in the post-operative period after LDLT. MATERIAL AND METHODS From January 2002 to May 2015, a total of 616 recipients underwent LDLT at our institute. The intra-operative and postoperative records of these patients were analyzed to study the cases of liver allograft hematoma...
January 5, 2017: Annals of Transplantation: Quarterly of the Polish Transplantation Society
https://www.readbyqxmd.com/read/28052604/optn-srtr-2015-annual-data-report-liver
#12
W R Kim, J R Lake, J M Smith, M A Skeans, D P Schladt, E B Edwards, A M Harper, J L Wainright, J J Snyder, A K Israni, B L Kasiske
Several notable developments in adult liver transplantation in the US occurred in 2015. The year saw the largest number of liver transplants to date, leading to reductions in median waiting time, in waitlist mortality for all model for end-stage liver disease categories, and in the number of candidates on the waiting list at the end of the year. Numbers of additions to the waiting list and of liver transplants performed in patients with hepatitis C virus infection decreased for the first time in recent years...
January 2017: American Journal of Transplantation
https://www.readbyqxmd.com/read/28051807/%C3%A2-graft-calcification-caused-by-a-torsion-of-the-hepatic-vein-after-a-living-related-donor-liver-transplantation
#13
Kuo-Shyang Jeng, Chun-Chieh Huang, Cheng-Kuan Lin, Chien-Chu Lin, Kuo-Hsin Chen
 The torsion of vessels after liver transplantation rarely occurs. Likewise, calcification of a liver graft has seldom been reported. This report details a case which had torsion of the left hepatic vein on the seventh day after living-related donor liver transplantation. The torsion was reduced soon after re-exploration; however, congestion with partial necrosis of the graft occurred. On the follow-up imaging studies, some resolution of necrosis and graft regeneration were found, yet geographic calcification of the liver graft appeared...
January 2017: Annals of Hepatology
https://www.readbyqxmd.com/read/28042248/comprehensive-guide-to-laparoscope-assisted-graft-harvesting-in-live-donors-for-living-donor-liver-transplantation-perspective-of-laparoscopic-vision
#14
Tomohide Hori, Toshimi Kaido, Taku Iida, Shintaro Yagi, Shinji Uemoto
BACKGROUND: A living donor (LD) for liver transplantation (LT) is the best target for minimally invasive surgery. Laparoscope-assisted surgery (LAS) for LDs has gradually evolved. A donor safety rate of 100% should be guaranteed. METHODS: We began performing LAS for LDs in June 2012. The aim of this report is to describe the surgical procedures of LAS in detail, discuss various tips and pitfalls, and address the potential for a smooth transition to more advanced LAS...
2017: Annals of Gastroenterology: Quarterly Publication of the Hellenic Society of Gastroenterology
https://www.readbyqxmd.com/read/28039901/living-donor-liver-transplantation-in-a-pediatric-patient-with-preexisting-yolk-sac-tumor
#15
Taiichi Wakiya, Yoshikazu Toyoki, Keinosuke Ishido, Daisuke Kudo, Norihisa Kimura, Shinji Tsutsumi, Tadashi Odagiri, Akiko Suto, Chiaki Uchida, Kenichi Hakamada
There is ongoing discussion regarding the indications and timing of LT for patients with a preexisting extrahepatic malignancy. We herein report a pediatric case that underwent LDLT after therapy for YST. The patient, a 13-year-old female with biliary atresia, had undergone portoenterostomy at 2 months of age. She developed a left ovarian tumor with a high serum alpha-fetoprotein concentration at 10 years of age. She underwent left oophorectomy and was diagnosed with ovarian YST (Stage I). After surgery, hepatopulmonary syndrome progressed gradually...
December 30, 2016: Pediatric Transplantation
https://www.readbyqxmd.com/read/28031549/clinicopathological-features-and-prognosis-of-hepatic-epithelioid-hemangioendothelioma-after-liver-resection-and-transplantation
#16
Dong-Hwan Jung, Shin Hwang, Seung-Mo Hong, Ki-Hun Kim, Young-Joo Lee, Chul-Soo Ahn, Deok-Bog Moon, Tae-Yong Ha, Gi-Won Song, Gil-Chun Park, Eunsil Yu, Sung-Gyu Lee
BACKGROUND Epithelioid hemangioendothelioma (EHE) is a rare vascular tumor. We present a single-center study on hepatic EHE cases treated by hepatic resection (HR) or liver transplantation (LT). MATERIAL AND METHODS Six HR patients with hepatic EHE were identified during 5 years from 2010 to 2014; EHE represented 0.13% (6 of 4572) of all primary liver tumors. Two LT recipients were also identified during 12 years from 2003 to 2014, who represented 0.06% (2 of 3576) of all adult LT patients. RESULTS Mean age of the patients was 42...
December 29, 2016: Annals of Transplantation: Quarterly of the Polish Transplantation Society
https://www.readbyqxmd.com/read/28030865/recent-advances-in-decellularization-and-recellularization-for-tissue-engineered-liver-grafts
#17
Yujia Wang, Clara T Nicolas, Harvey S Chen, Jeffery J Ross, Silvana B De Lorenzo, Scott L Nyberg
Liver transplantation from deceased or living human donors remains the only proven option for patients with end-stage liver disease. However, the shortage of donor organs is a significant clinical concern that has led to the pursuit of tissue-engineered liver grafts generated from decellularized liver extracellular matrix and functional cells. Investigative efforts on optimizing both liver decellularization and recellularization protocols have been made in recent decades. In the current review, we briefly summarize these advances, including the generation of high-quality liver extracellular matrix scaffolds, evaluation criteria for quality control, modification of matrix for enhanced properties, and reseeding strategies...
December 29, 2016: Cells, Tissues, Organs
https://www.readbyqxmd.com/read/28027616/living-donor-liver-transplantation-using-a-right-anterior-section-of-the-liver
#18
Kyung-Suk Suh, Hyo-Sin Kim, Nam-Joon Yi, Kwang-Woong Lee, Suk Kyun Hong, Kyung Chul Yoon, Adianto Nugroho, Hyeyoung Kim
No abstract text is available yet for this article.
December 27, 2016: Liver Transplantation
https://www.readbyqxmd.com/read/28027615/living-donor-liver-transplantation-using-an-extended-right-lateral-sector-graft
#19
N Yoshida, T Takamoto, T Hashimoto, Y Maruyama, H Abe, K Shimada, T Takayama, M Makuuchi
There are three grafts (left, right and right lateral sector [RLS]) available for adult living donor liver transplantation (LDLT), and we herein report LDLT performed using an extended RLS graft. An extended RLS graft is an RLS plus right paramedian dorsal sector (RPMS-dorsal) graft. In this case, the proportion of the RLS graft of the predicted graft volume (GV) to the recipient's standard liver volume (SLV) was only 17.7%, preoperatively. A three-dimensional (3D) analysis, showed that the RPMS-dorsal branches of the portal veins branched from the posterior trunk not the anterior trunk...
December 27, 2016: Liver Transplantation
https://www.readbyqxmd.com/read/28027592/outcomes-of-liver-retransplantation-in-patients-with-primary-sclerosing-cholangitis
#20
Jacqueline B Henson, Yuval A Patel, Lindsay Y King, Jiayin Zheng, Shein-Chung Chow, Andrew J Muir
: Liver retransplantation in patients with primary sclerosing cholangitis (PSC) has not been well studied. The aims of this study were to characterize patients with PSC listed for and undergoing retransplantation and to describe the outcomes in these patients. The United Network for Organ Sharing/Organ Procurement and Transplantation Network database was used to identify all primary liver transplantations and subsequent relistings and first retransplantations in adults with PSC between 1987 and 2015...
December 27, 2016: Liver Transplantation
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