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https://www.readbyqxmd.com/read/28343221/abandoning-prophylactic-abdominal-drainage-after-hepatic-surgery-10-years-of-no-drain-policy-in-an-enhanced-recovery-after-surgery-environment
#1
Edgar M Wong-Lun-Hing, Victor van Woerden, Toine M Lodewick, Marc H A Bemelmans, Steven W M Olde Damink, Cornelis H C Dejong, Ronald M van Dam
BACKGROUND: Routine prophylactic abdominal drainage after hepatic surgery is still being debated, as it may be unnecessary, possibly harmful, and uncomfortable for patients. This study evaluated the safety of a no-drain policy after liver resection within an Enhanced Recovery after Surgery (ERAS) programme. METHODS: All hepatectomies performed without prophylactic drainage during 2005-2014 were included. Primary end points were resection-surface-related (RSR) morbidity, defined as the presence of postoperative biloma, hemorrhage or abscess, and reinterventions...
March 25, 2017: Digestive Surgery
https://www.readbyqxmd.com/read/28343002/pulmonary-metastatic-angiosarcoma-from-scalp-with-fatal-complication-a-case-report
#2
Yung-Sheng Cheng, Tim-Mo Chen, Wen-Chiuan Tsai, Tsai-Wang Huang
INTRODUCTION: Angiosarcoma is a rare malignant neoplasm with poor prognosis. Angiosarcoma of the scalp is frequently recurs locally, and metastasizes early despite various treatments. The common sites of metastatic are lung, liver, and lymph nodes. Pulmonary metastasis with hemoptysis and pneumothorax is rare but threatening. PRESENTATION OF CASE: A 77-year-old male had recurrent angiosarcoma of the scalp even with post operation radiotherapy. At the same time, recurrent pneumothorax was noted, thus he underwent wedge resection of the right upper lobe of the lung plus pleural biopsy...
February 20, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/28342361/giant-leiomyosarcoma-of-the-rectum-with-lymph-node-metastasis-a-case-report-and-review-of-the-literature
#3
Hiroyuki Anzai, Hiroaki Nozawa, Junichiro Tanaka, Koji Yasuda, Kensuke Otani, Takeshi Nishikawa, Toshiaki Tanaka, Tomomichi Kiyomatsu, Keisuke Hata, Kazushige Kawai, Tetsuo Ushiku, Soichiro Ishihara, Toshimi Takano, Masashi Fukayama, Toshiaki Watanabe
INTRODUCTION: Leiomyosarcoma of the gastrointestinal tract is very rare, with a reported frequency of less than 0.1% of all malignancies of the colorectum. It is important to diagnose leiomyosarcoma definitively by immunohistochemical profiling of smooth muscle actin, desmin, and CD34. True leiomyosarcoma of the colorectum diagnosed by immunnohistochemical profiling is extremely rare that only 13 reports have been published in reviews of resected gastrointestinal mesenchymal tumors after 1998...
March 8, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/28339094/f221y-mutation-in-hepatitis-b-virus-reverse-transcriptase-is-associated-with-hepatocellular-carcinoma-prognosis-following-liver-resection
#4
Huiming Li, Jian'an Jia, Mengmeng Wang, Hui Wang, Xing Gu, Meng Fang, Chunfang Gao
Hepatitis B virus (HBV) reverse transcriptase (RT) is encoded by the polymerase gene in the reverse transcriptase region, which overlaps with the S gene. The association between mutations of HBV RT and the pathobiological features of hepatocellular carcinoma (HCC) remain to be elucidated. The present study aimed to examine mutations in this region of the HBV genome and its clinical significance. Briefly, HBV total DNA was extracted from 84 pairs of HCC tumor tissue and corresponding adjacent non‑tumor tissue samples...
March 23, 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/28338595/3-0-nacl-adenosine-lidocaine-mg-2-alm-bolus-and-4-hours-drip-infusion-reduces-non-compressible-hemorrhage-by-60-in-a-rat-model
#5
Hayley L Letson, Geoffrey P Dobson
BACKGROUND: Noncompressible torso hemorrhage is the leading cause of potentially survivable trauma in far-forward combat environments. Our aim was to examine the effect of small-volume 3% NaCl adenosine, lidocaine and Mg (ALM) bolus and 0.9% NaCl/ALM 'drip' on survivability and cardiac/gut/kidney function in a rat model of hepatic hemorrhage and shock. METHODS: Male Sprague-Dawley rats (428±4 g) were anesthetized and randomly assigned to one of five groups (n=16): 1) Sham, 2) No Treatment, 3) Saline controls, 4) ALM therapy and 5) Hextend®...
March 23, 2017: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/28338523/laparoscopic-anatomic-segment-6-liver-resection-using-the-glissonian-approach
#6
Hanlim Choi, Ho-Seong Han, Yoo-Seok Yoon, Jai Young Cho, YoungRok Choi, Jae Yool Jang
INTRODUCTION: Laparoscopic liver resection has become important procedure for malignant liver disease. In this report, we describe the relevant technical maneuvers and perioperative outcomes in laparoscopic anatomic segment 6 liver resection using the Glissonian approach. PATIENTS AND METHODS: From March 2003 and October 2015, 7 patients who diagnosed hepatocellular carcinoma had undergone laparoscopic anatomic segment 6 liver resection at the single institution...
March 23, 2017: Surgical Laparoscopy, Endoscopy & Percutaneous Techniques
https://www.readbyqxmd.com/read/28338509/patterns-timing-and-predictors-of-recurrence-following-pancreatectomy-for-pancreatic-ductal-adenocarcinoma
#7
Vincent P Groot, Neda Rezaee, Wenchuan Wu, John L Cameron, Elliot K Fishman, Ralph H Hruban, Matthew J Weiss, Lei Zheng, Christopher L Wolfgang, Jin He
OBJECTIVE: To describe accurately the pattern, timing, and predictors of disease recurrence after a potentially curative resection for pancreatic ductal adenocarcinoma (PDAC). SUMMARY BACKGROUND DATA: After surgery for PDAC, most patients will develop disease recurrence. Understanding the patterns and timing of disease failure can help guide improvements in therapy. METHODS: Patients who underwent pancreatectomy for PDAC at the Johns Hopkins Hospital between 2000 and 2010 were included...
March 23, 2017: Annals of Surgery
https://www.readbyqxmd.com/read/28338152/-development-and-future-of-minimally-invasive-surgery-in-western-china
#8
Peiwu Yu, Yingxue Hao
There are vast land and lots of people in western China, but the economy developing is relatively slow. However, the minimally invasive surgery was carried out firstly in China. Moreover, the type, number and difficulty of the minimally invasive surgery increased year by year. Especially, in the western area of China, Dr Zhou Zongguang, Yu Peiwu and Zheng Shuguo et al. have performed much pioneering work in laparoscopic surgery for rectal cancer, gastric cancer and laparoscopic liver resection. They led the standard development of minimally invasive in China...
March 25, 2017: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/28333846/prognostic-value-of-fluorine-18-fluorodeoxyglucose-uptake-of-bone-marrow-on-positron-emission-tomography-computed-tomography-for-prediction-of-disease-progression-in-cervical-cancer
#9
Jeong Won Lee, Seob Jeon, Seong Taek Mun, Sang Mi Lee
OBJECTIVE: This study aimed to evaluate the prognostic value of fluorine-18 fluorodeoxyglucose (FDG) uptake of bone marrow (BM) on positron emission tomography (PET)/computed tomography in patients with uterine cervical cancer. METHODS: One hundred forty-five patients with cervical cancer who underwent staging FDG PET/computed tomography and subsequent surgical resection or chemoradiotherapy were retrospectively enrolled in the study. Mean BM FDG uptake (BM standardized uptake value [SUV]) and BM-to-liver uptake ratio of FDG uptake (BLR) were measured...
March 23, 2017: International Journal of Gynecological Cancer
https://www.readbyqxmd.com/read/28332060/risk-factors-for-postoperative-ascites-in-patients-undergoing-liver-resection-for-hepatocellular-carcinoma
#10
Takahiro Yoshikawa, Takeo Nomi, Daisuke Hokuto, Satoshi Yasuda, Chihiro Kawaguchi, Takatsugu Yamada, Hiromichi Kanehiro, Yoshiyuki Nakajima
BACKGROUND: Postoperative ascites is a common complication after liver resection. This study aimed to identify the risk factors for ascites in patients after liver resection and the relationship between postoperative ascites and other complications. METHODS: We retrospectively analyzed data that were obtained from 266 patients who underwent liver resection for treating hepatocellular carcinoma between 2008 and 2015. Postoperative ascites was defined as a daily ascitic fluid drainage exceeding 500 mL on postoperative day 3 or later...
March 22, 2017: World Journal of Surgery
https://www.readbyqxmd.com/read/28332034/patterns-of-initial-recurrence-in-gastric-adenocarcinoma-in-the-era-of-preoperative-therapy
#11
Naruhiko Ikoma, Hsiang-Chun Chen, Xuemei Wang, Mariela Blum, Jeannelyn S Estrella, Keith Fournier, Paul Mansfield, Jaffer Ajani, Brian D Badgwell
BACKGROUND: We sought to determine the sites of recurrence and identify predicting factors for recurrence and survival in patients who underwent gastrectomy for adenocarcinoma at an institution where preoperative therapy is commonly used for advanced gastric cancer. METHODS: We collected clinicopathologic data and sites of recurrence from a prospectively maintained database of patients who underwent potentially curative resection of gastric or gastroesophageal adenocarcinoma at our institution in 1995-2014, and we assessed associations between these characteristics and recurrence patterns and survival...
March 22, 2017: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/28331844/a-single-institution-report-of-19-hepatocellular-carcinoma-patients-with-bile-duct-tumor-thrombus
#12
Anon Chotirosniramit, Akkaphod Liwattanakun, Worakitti Lapisatepun, Wasana Ko-Iam, Trichak Sandhu, Sunhawit Junrungsee
BACKGROUND: Obstructive jaundice caused due to bile duct tumor thrombus (BDTT) in a hepatocellular carcinoma (HCC) patient is an uncommon event. This study reports our clinical experiences and evaluates the outcomes of HCC patients with BDTT in a single institution. METHODS: A retrospective review of 19 HCC patients with secondary obstructive jaundice caused due to BDTT during a 15-year period was conducted. RESULTS: At the time of diagnosis, 14 (73...
2017: Journal of Hepatocellular Carcinoma
https://www.readbyqxmd.com/read/28331142/usefulness-of-color-coding-resected-samples-from-a-pancreaticoduodenectomy-with-tissue-marking-dyes-for-a-detailed-examination-of-surgical-margin-surrounding-the-uncinate-process-of-the-pancreas
#13
Satoshi Mizutani, Hideyuki Suzuki, Takayuki Aimoto, Seiji Yamagishi, Keisuke Mishima, Masanori Watanabe, Yasuhiko Kitayama, Norio Motoda, Saiko Isshiki, Eiji Uchida
BACKGROUND: Characteristics of a cancer-positive margin around a resected uncinate process of the pancreas (MUP) due to a pancreticoduodenectomy are difficult to understand by standardized evaluation because of its complex anatomy. The purposes of this study were to subclassify the MUP with tissue marking dyes of different colors and to identify the characteristics of sites that showed positivity for cancer cells in patients with pancreatic head carcinoma who underwent circumferential superior mesenteric arterial nerve plexus-preserving pancreaticoduodenectomy...
2017: Journal of Nippon Medical School, Nippon Ika Daigaku Zasshi
https://www.readbyqxmd.com/read/28331137/evaluation-of-surgical-procedures-for-t2-gallbladder-cancer-in-terms-of-recurrence-and-prognosis
#14
Ryuichi Kawahara, Takahisa Shirahama, Shyoichirou Arai, Daisuke Muroya, Yoriko Nomura, Shogo Fukutomi, Nobuhisa Shirahama, Katsuaki Takagi, Yuichi Goto, Masanori Akashi, Yuichirou Maruyama, Hisamune Sakai, Hiroto Ishikawa, Toru Hisaka, Masafumi Yasunaga, Hiroyuki Horiuchi, Koji Okuda, Yoshito Akagi, Hiroyuki Tanaka
T2 (tumor invades perimuscular connective tissue; no extension beyond serosa or into liver) gallbladder cancer has generally been treated by S4aS5 subsegmentectomy (S4aS5 HR). We investigated the therapeutic effect of full-thickness cholecystectomy (FC) and gallbladder bed resection (GBR), in terms of tumor location and resection margin (distance from the tumor). At our department we employ the following protocol to determine the extent of resection needed to achieve R0 status: (1) A tumor located in the gallbladder fundus (Gf) or body (Gb) and only on the free peritoneal side was classified as P-type, for which full-thickness cholecystectomy and regional lymph node dissection were performed...
March 22, 2017: Kurume Medical Journal
https://www.readbyqxmd.com/read/28328956/the-impact-of-pulmonary-metastasectomy-in-patients-with-previously-resected-colorectal-cancer-liver-metastases
#15
Armin Wiegering, Johannes Riegel, Johanna Wagner, Volker Kunzmann, Johannes Baur, Thorsten Walles, Ulrich Dietz, Stefan Loeb, Christoph-Thomas Germer, Ulrich Steger, Ingo Klein
BACKGROUND: 40-50% of patients with colorectal cancer (CRC) will develop liver metastases (CRLM) during the course of the disease. One third of these patients will additionally develop pulmonary metastases. METHODS: 137 consecutive patients with CRLM, were analyzed regarding survival data, clinical, histological data and treatment. Results were stratified according to the occurrence of pulmonary metastases and metastases resection. RESULTS: 39% of all patients with liver resection due to CRLM developed additional lung metastases...
2017: PloS One
https://www.readbyqxmd.com/read/28328863/surgical-outcomes-of-laparoscopic-versus-open-liver-resection-for-hepatocellular-carcinoma-for-various-resection-extent
#16
Junhua Chen, Hongyu Li, Fei Liu, Bo Li, Yonggang Wei
Although the number of laparoscopic liver resections (LRRs) has increased, studies of surgical outcomes in comparison with the conventional open approach are limited. The purpose of this study was to analyze the surgical outcomes (safety and efficacy) of LLR versus open liver resection (OLR) for hepatocellular carcinoma (HCC).We collected data on all patients who received liver resection for HCC between April 2015 and September 2016 in our institution, and retrospectively investigated the demographic and perioperative data, and also surgical outcomes...
March 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28328858/retroperitoneal-and-intrahepatic-metastasis-from-primary-clear-cell-carcinoma-of-the-liver-a-case-report-and-review-of-the-literature
#17
Junjie Xiong, Du He, Weiming Hu, Xubao Liu
BACKGROUND: Hepatocellular carcinoma (HCC) is a major cause of cancer-related mortality worldwide and the incidence is increasing as a result of growing hepatitis B and C virus infections. Primary clear cell carcinoma of the liver (PCCCL) is a rare subgroup of primary HCC, which has low metastatic potential and infrequently reported in literature. Retroperitoneal and intrahepatic metastasis of PCCCL has not been reported previously. CASE SUMMARY: Here, we present a 55-year-old male with retroperitoneal and intrahepatic metastasis of PCCCL who is managed with surgical method and transcatheter arterial chemoembolization (TACE) at our institution...
March 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28328851/survival-outcomes-of-hepatocellular-carcinoma-resection-with-postoperative-complications-a-propensity-score-matched-analysis
#18
Kenneth S H Chok, Millies M Y Chan, Wing Chiu Dai, Albert C Y Chan, Tan To Cheung, Tiffany C L Wong, Wong Hoi She, Chung Mau Lo
Curative resection remains the only hope of cure for hepatocellular carcinoma (HCC), but postoperative complications can have a significant impact on long-term survival. However, only scarce data on such impact can be found in the literature.This retrospective study reviewed the prospectively collected data of patients who underwent primary liver resection for HCC at our hospital during the period from December 1989 to December 2014. Patients with and without postoperative complications were compared. A 1:1 propensity score matching was adopted by matching age, comorbidity, Model of End-stage Liver Disease score, tumor stage, and extent of resection...
March 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28327196/primary-hepatic-angiomyolipoma-immunohistochemistry-and-electron-microscopic-observations-a-case-report
#19
Hidefumi Kubo, Hitoshi Yamazaki, Takemichi Okada, Yoshihito Takahashi, Yatsushi Nishi, Hiroaki Yokomori
BACKGROUND: Hepatic angiomyolipomas are a rare, benign group of mesenchymal tumors in the liver. Hepatic angiomyolipoma is sometimes misdiagnosed as hepatocellular carcinoma, and there is the possibility of a malignant transformation. Hence, the accurate diagnosis of this disorder is necessary. CASE PRESENTATION: A 64-year-old Japanese man was observed to have a space-occupying lesion of 15-mm diameter in the liver during a follow-up examination for a previously resected cecal carcinoma...
March 22, 2017: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/28327002/use-of-imaging-to-predict-complete-response-of-colorectal-liver-metastases-after-chemotherapy-mr-imaging-versus-ct-imaging
#20
Min Jung Park, Nurhee Hong, Kyunghwa Han, Min Ju Kim, Yoon Jin Lee, Yang Shin Park, Sung Eun Rha, Sumi Park, Won Jae Lee, Seong Ho Park, Chang Hee Lee, Chung Mo Nam, Chansik An, Hye Jin Kim, Honsoul Kim, Mi-Suk Park
Purpose To compare the diagnostic performances of contrast agent-enhanced computed tomography (CT) and gadolinium ethoxybenzyl diethylenetriamine pentaacetic acid-enhanced liver magnetic resonance (MR) imaging (referred to as EOB MR imaging) in the evaluation of disappearing colorectal liver metastases (CRLMs) after chemotherapy. Materials and Methods The eight institutional review boards approved this retrospective study and waived the requirement for informed consent. On the basis of retrospective searches in eight hospitals, 87 patients with 393 CRLMs, each patient with one or more CRLM that later disappeared on contrast-enhanced CT scans after chemotherapy, and subsequently underwent surgery for the CRLMs, were enrolled...
March 22, 2017: Radiology
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