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Eva Slapnik, Martin Rauber, Spela Tadel Kocjancic, Anja Jazbec, Marko Noc, Peter Radsel
AIM: Only up to 20% of patients with out-of-hospital cardiac arrest (OHCA) receive immediate and optimal initial cardiac resuscitation and consequently regain consciousness soon after return of spontaneous circulation (ROSC). In the present study, we compared the outcome of conscious survivors of OHCA presenting with ST-elevation myocardial infarction (STEMI) in post-resuscitation electrocardiogram undergoing immediate invasive coronary strategy with randomly selected STEMI patients without preceding OHCA undergoing primary PCI...
September 20, 2018: Resuscitation
Jiwei Zhang, Pengshan Zhao, Jiecai Zhao, Guoxiong Chen
Sand rice (Agriophyllum squarrosum), a diploid Amaranthaceae species within the order Caryophyllalles, has potential as a crop in response to concerns about ongoing climate change and future food security. Modifying the weedy traits, such as dense trichomes, is important for the domestication of sand rice. In this study, an ethyl methanesulfonate (EMS) induced Agriophyllum squarrosum trichomeless mutant (astcl1) was isolated and genetic analysis revealed that this mutant was controlled by a single recessive locus...
September 11, 2018: Journal of Plant Physiology
Alexander W Gundlach-Graham, Lyndsey Hendriks, Kamyar Mehrabi, Detlef Günther
Many modern time-of-flight mass spectrometry (TOFMS) instruments use fast analog-to-digital conversion (ADC) with high-speed digitizers to record mass spectra with extended dynamic range (compared to time-to-digital conversion).  The extended dynamic range offered by ADC detection is critical for accurate measurement of transient events.  However, the use of fast ADC also increases the variance of the measurements by sampling the gain statistics of electron multipliers (EMs) used for detection.  The influence of gain statistics on the shape of TOF signal distributions is especially pronounced at low count rates and is a major contributor to measurement variance...
September 21, 2018: Analytical Chemistry
Carlos A R Herdeiro, Eugen Radu, Nicolas Sanchis-Gual, José A Font
Extended scalar-tensor Gauss-Bonnet (ESTGB) gravity has been recently argued to exhibit spontaneous scalarization of vacuum black holes (BHs). A similar phenomenon can be expected in a larger class of models, which includes, e.g., Einstein-Maxwell scalar (EMS) models, where spontaneous scalarization of electrovacuum BHs should occur. EMS models have no higher curvature corrections, a technical simplification over ESTGB models that allows us to investigate, fully nonlinearly, BH scalarization in two novel directions...
September 7, 2018: Physical Review Letters
Hannah Gardener, Paul E Pepe, Tatjana Rundek, Kefeng Wang, Chuanhui Dong, Maria Ciliberti, Carolina Gutierrez, Antonio Gandia, Peter Antevy, Wayne Hodges, Nils Mueller-Kronast, Charles Sand, Jose G Romano, Ralph L Sacco
OBJECTIVE: Demographic differences (race/ethnicity/sex) in 9-1-1 emergency medical services (EMS) access and utilization have been reported for various time-dependent critical illnesses along with associated outcome disparities. However, data are lacking with respect to measuring the various components of time taken to reach definitive care facilities following the onset of acute stroke symptoms (i.e., stroke onset to 9-1-1 call, EMS response, time on-scene, transport interval) and particularly with respect to any differences across ethnicities and sex...
September 21, 2018: Prehospital Emergency Care
Eveline A J van Rein, Said Sadiqi, Koen W W Lansink, Rob A Lichtveld, Risco van Vliet, F Cumhur Oner, Luke P H Leenen, Mark van Heijl
PURPOSE: Severely injured patients should be treated at higher-level trauma centres, to improve chances of survival and avert life-long disabilities. Emergency medical service (EMS) providers must try to determine injury severity on-scene, using a prehospital trauma triage protocol, and decide the most appropriate type of trauma centre. The objective of this study is to investigate the role of EMS provider judgment in the prehospital triage process of trauma patients, by analysing the compliance rate to the protocol and administering a questionnaire among EMS providers...
September 20, 2018: European Journal of Trauma and Emergency Surgery: Official Publication of the European Trauma Society
Ikwan Chang, Young Sun Ro, Sang Do Shin, Kyoung Jun Song, Jeong Ho Park, So Yeon Kong
OBJECTIVE: We aimed to demonstrate the association of bystander cardiopulmonary resuscitation (BCPR) with survival outcomes after pediatric out-of-hospital cardiac arrest (OHCA) by community property value groups. METHODS: This observational study enrolled all emergency medical services (EMS)-treated pediatric OHCAs in Korea between 2012 and 2015. Enrolled patients were divided into three groups: BCPR with dispatcher-assistance (DA), BCRP-without-DA, and no-BCPR...
September 17, 2018: Resuscitation
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October 2018: Annals of Emergency Medicine
Akihiro Hirakawa, Toshihiro Hatakeyama, Daisuke Kobayashi, Chika Nishiyama, Akiko Kada, Takeyuki Kiguchi, Takashi Kawamura, Taku Iwami
BACKGROUND: The quality of cardiopulmonary resuscitation (CPR) performed by emergency medical services (EMS) personnel affects patient outcomes after cardiac arrest. A CPR feedback device with an accelerometer mounted on a defibrillator can monitor the motion of the patient's sternum to display and record CPR quality in real time. To evaluate the utility of real-time feedback, debriefing, and retraining using a CPR feedback device outside of the hospital, an open-label, cluster randomized controlled trial will be conducted in five municipalities of Osaka Prefecture, Japan...
September 20, 2018: Trials
Lauren Brasile, Nicholas Henry, Giuseppe Orlando, Bart Stubenitsky
BACKGROUND: The potential of a Mesenchymal Stem Cell (MSC) therapy to accelerate the repair of ischemically damaged human kidneys during 24 hours of warm perfusion was evaluated. The hypothesis was that by administering MSC directly to the renal tissue, there would be an improved opportunity for cellular repair mediated by intrarenal paracrine effects. METHODS: Studies were performed using the Exsanguinous Metabolic Support (EMS) tissue-engineering platform. Five pairs of human kidney allografts from donation after cardiac death (DCD) donors were studied...
September 17, 2018: Transplantation
Salma Hussain Abu-Grain, Sanaa Sadiq Alsaad, Dalia Yahia El Kheir
Background: Being the first in-line care providers, primary health-care (PHC) physicians may encounter all forms of emergencies, ranging from minor complaints to life-threatening events. This wide variation of cases challenges the physicians to be competent in emergency medicine. Informative literature describing and assessing the factors affecting PHC physicians' emergency medical services (EMS)-related practice is deficient (nationally and internationally). The aim of this study is to assess PHC physicians' practice related to EMS, the factors affecting it, as well as their learning needs and preferred methods of continuous training in emergency medicine...
July 2018: Journal of Family Medicine and Primary Care
Shuo Zhang, Hui Zhi, Wen Li, Jianguo Shan, Chanjuan Tang, Guanqing Jia, Sha Tang, Xianmin Diao
A yellow-green leaf mutant was isolated from EMS-mutagenized lines of Setaria italica variety Yugu1. Map-based cloning revealed the mutant gene is a homolog of Arabidopsis thaliana AtEGY1 . EGY1 (ethylene-dependent gravitropism-deficient and yellow-green 1) is an ATP-independent metalloprotease (MP) that is required for chloroplast development, photosystem protein accumulation, hypocotyl gravitropism, leaf senescence, and ABA signal response in A. thaliana . However, the function of EGY1 in monocotyledonous C4 plants has not yet been described...
2018: Frontiers in Plant Science
Amitha M V Sevanthi, Prashant Kandwal, Prashant B Kale, Chandra Prakash, M K Ramkumar, Neera Yadav, Ajay K Mahato, V Sureshkumar, Motilal Behera, Rupesh K Deshmukh, P Jeyaparakash, Meera K Kar, S Manonmani, Raveendran Muthurajan, K S Gopala, Sarla Neelamraju, M S Sheshshayee, P Swain, Ashok K Singh, N K Singh, Trilochan Mohapatra, R P Sharma
The Indian initiative, in creating mutant resources for the functional genomics in rice, has been instrumental in the development of 87,000 ethylmethanesulfonate (EMS)-induced mutants, of which 7,000 are in advanced generations. The mutants have been created in the background of Nagina 22, a popular drought- and heat-tolerant upland cultivar. As it is a pregreen revolution cultivar, as many as 573 dwarf mutants identified from this resource could be useful as an alternate source of dwarfing. A total of 541 mutants, including the macromutants and the trait-specific ones, obtained after appropriate screening, are being maintained in the mutant garden...
2018: Frontiers in Plant Science
Emily Andrew, Colin Jones, Michael Stephenson, Tony Walker, Stephen Bernard, Peter Cameron, Karen Smith
OBJECTIVE: In Victoria, Australia, Emergency Medical Service (EMS) demand has increased almost 5% per annum over the past 5 years. This may adversely affect response times to time-critical patients. Additionally, >55% of cases have received Code 1 (lights/sirens) responses. Primary telephone triage occurs using the Medical Priority Dispatch System (MPDS); however, MPDS is reported to be highly sensitive, with common over-triage. The present study describes the methodology applied to better align the response allocated to MPDS determinant codes with patient acuity...
September 19, 2018: Emergency Medicine Australasia: EMA
Xuan Zhao, Liru Dou, Zhizhong Gong, Xiangfeng Wang, Tonglin Mao
Proper regulation of seed germination is essential for the successful propagation of a plant. The transcription factor ABSCISIC ACID INSENSITIVE5 (ABI5) of the abscisic acid (ABA) signaling pathway plays a central role in the inhibition of seed germination. ABI5 is precisely regulated by the core ABA signaling components and multiple other factors. However, the complex regulatory network of ABI5 remains largely unknown. In this study, we determined the biochemical interaction between ABI5 and the BRINSENSITIVE1 (BRI1)-EMS-SUPPRESSOR1 (BES1) transcription factor of the brassinosteroid (BR) signaling pathway, as well as the function of BES1 regulating ABI5 during seed germination in Arabidopsis...
September 19, 2018: New Phytologist
Sabnam Mahmuda, Adam Wade-Vallance, Alix Stosic, Dale Guenter, Michelle Howard, Gina Agarwal, Brent McLeod, Ricardo Angeles
INTRODUCTION: Frequent users of emergency medical services (EMS) have disproportionately high 9-1-1 call frequency. Evidence suggests that this small group burdens the health care system, leading to misallocation of already-limited health resources. AIM: To understand frequent users' perceptions and experiences regarding EMS, as well as the driving factors underlying their frequent use. METHOD: A grounded theory approach guided our qualitative research process...
September 15, 2018: Health Promotion Practice
Francis X Feld
Since the early 1970s, initial management of patients with suspected spinal injuries has involved the use of a cervical collar and long spine board for full immobilization, which was thought to prevent additional injury to the cervical spine. Despite a growing body of literature demonstrating the detrimental effects and questionable efficacy of spinal immobilization, the practice continued until 2013, when the National Association of EMS Physicians issued a position statement1 calling for a reduction in the use of spinal immobilization and a shift to spinal-motion restriction...
September 17, 2018: Journal of Athletic Training
Christopher Berry, Douglas Kupas, Mark Olaf, Anne Knorr, Andrea Berger
BACKGROUND: The approach to managing out-of-hospital cardiac arrest (OOHCA) has generally involved either minimal on-scene resuscitation to reduce time to arrival at hospital or extended care at the scene to increase the chance of return of spontaneous circulation (ROSC) before transport. This study compared patient outcomes across EMS agencies with respect to the duration of on-scene time. We hypothesized that EMS agencies with greater average time on-scene would have more favorable outcomes...
September 15, 2018: Prehospital Emergency Care
Deepthi Dechamma, Santosh Maruthy
PURPOSE: A longstanding finding in persons who stutter is that stuttering frequency significantly reduces during choral reading when compared to the solo reading condition. Here, we tested the hypothesis that this decrease in stuttering frequency may be because speech of the normal speaker dictates the speech rhythm of a person who stutters. We used an automated, sensitive acoustic technique-Envelope Modulation Spectral (EMS) analysis- that allowed us to document speech rhythm. METHOD: Seventeen adults who stutter (AWS) read sentences under two conditions: solo reading and choral reading...
September 8, 2018: Journal of Fluency Disorders
Eli Jaffe, Ziv Dadon, Evan Avraham Alpert
Multi-casualty incidents (MCIs) continue to occur throughout the world, whether they be mass shootings or natural disasters. Prehospital emergency services have done a professional job at stabilizing and transporting the victims to local hospitals. When there are multiple casualties, there may not be enough professional responders to care for the injured. Bystanders and organized volunteer first responders have often helped in extricating the victims, stopping the bleeding, and aiding in the evacuation of the victims...
September 17, 2018: Prehospital and Disaster Medicine
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