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https://www.readbyqxmd.com/read/29346613/review-of-chronic-non-cancer-pain-research-among-aboriginal-people-in-canada
#1
Nancy Julien, Anaïs Lacasse, Oscar Labra, Hugo Asselin
Purpose: Aboriginal people in Canada are disproportionately affected by chronic illnesses, compared to non-Aboriginal Canadians. The purpose of this review was to determine whether differences exist between the two groups with respect to chronic non-cancer pain (CNCP) in order to better inform clinical practice and to identify research gaps. Data sources: Four electronic databases were searched for the period of 1990-2015. Study selection: Only English and French language original studies that examined CNCP prevalence, assessment tools and beliefs among Aboriginal people in Canada were considered...
January 16, 2018: International Journal for Quality in Health Care
https://www.readbyqxmd.com/read/29346399/the-motivation-based-calving-facility-social-and-cognitive-factors-influence-isolation-seeking-behaviour-of-holstein-dairy-cows-at-calving
#2
Maria Vilain Rørvang, Mette S Herskin, Margit Bak Jensen
In order to improve animal welfare it is recommended that dairy farmers move calving cows from the herd to individual pens when calving is imminent. However, the practicality of moving cows has proven a challenge and may lead to disturbance of the cows rather than easing the process of calving. One solution may be to allow the cow to seek isolation prior to calving. This study examined whether pre-parturient dairy cows will isolate in an individual calving pen placed in a group calving setting and whether a closing gate in this individual calving pen will cause more cows to isolate prior to calving...
2018: PloS One
https://www.readbyqxmd.com/read/29346376/evaluating-the-sustainability-scalability-and-replicability-of-an-sth-transmission-interruption-intervention-the-deworm3-implementation-science-protocol
#3
Arianna Rubin Means, Sitara S R Ajjampur, Robin Bailey, Katya Galactionova, Marie-Claire Gwayi-Chore, Katherine Halliday, Moudachirou Ibikounle, Sanjay Juvekar, Khumbo Kalua, Gagandeep Kang, Pallavi Lele, Adrian J F Luty, Rachel Pullan, Rajiv Sarkar, Fabian Schär, Fabrizio Tediosi, Bryan J Weiner, Elodie Yard, Judd Walson
Hybrid trials that include both clinical and implementation science outcomes are increasingly relevant for public health researchers that aim to rapidly translate study findings into evidence-based practice. The DeWorm3 Project is a series of hybrid trials testing the feasibility of interrupting the transmission of soil transmitted helminths (STH), while conducting implementation science research that contextualizes clinical research findings and provides guidance on opportunities to optimize delivery of STH interventions...
January 2018: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/29346375/how-do-we-reach-the-girls-and-women-who-are-the-hardest-to-reach-inequitable-opportunities-in-reproductive-and-maternal-health-care-services-in-armed-conflict-and-forced-displacement-settings-in-colombia
#4
Juan Carlos Rivillas, Raul Devia Rodriguez, Gloria Song, Andréanne Martel
OBJECTIVES: This paper assesses inequalities in access to reproductive and maternal health services among females affected by forced displacement and sexual and gender-based violence in conflict settings in Colombia. This was accomplished through the following approaches: first, we assessed the gaps and gradients in three selected reproductive and maternal health care services. Second, we analyzed the patterns of inequalities in reproductive and maternal health care services and changes over time...
2018: PloS One
https://www.readbyqxmd.com/read/29346101/stacked-denoising-tensor-auto-encoder-for-action-recognition-with-spatiotemporal-corruptions
#5
Chengcheng Jia, Ming Shao, Sheng Li, Handong Zhao, Yun Fu
Spatially or temporally corrupted action videos are impractical for recognition via vision or learning models. It usually happens when streaming data are captured from unintended moving cameras, which bring occlusion or camera vibration and accordingly result in arbitrary loss of spatiotemporal information. In reality, it is intractable to deal with both spatial and temporal corruptions at the same time. In this paper, we propose a coupled stacked denoising tensor auto-encoder (CSDTAE) model, which approaches this corruption problem in a divide-and-conquer fashion by jointing both the spatial and temporal schemes together...
April 2018: IEEE Transactions on Image Processing: a Publication of the IEEE Signal Processing Society
https://www.readbyqxmd.com/read/29345937/hole-hopping-rates-in-organic-semiconductors-a-second-order-cumulant-approach
#6
Alessandro Landi, Raffaele Borrelli, Amedeo Capobianco, Amalia Velardo, Andrea Peluso
Second-order cumulant expansion of the time dependent reduced density matrix has been employed to evaluate hole hopping rates in pentacene, tetracene, picene, and rubrene homodimers. The cumulant expansion is a full quantum mechanical approach, which allows to use in computations the whole set of nuclear coordinates of the system, including both the effects of the equilibrium position displacements and of normal mode mixing upon hole transfer. The time dependent populations predicted by cumulant approach are in good agreement with those obtained by numerical solution of time dependent Schrödinger equation, even for ultrafast processes, where the Fermi Golden Rule fails...
January 18, 2018: Journal of Chemical Theory and Computation
https://www.readbyqxmd.com/read/29345805/is-the-widely-used-two-factor-structure-of-the-ruminative-responses-scale-invariant-across-different-samples-of-women
#7
Paola Lucena-Santos, José Pinto-Gouveia, Sérgio A Carvalho, Margareth da Silva Oliveira
OBJECTIVES: Although the Ruminative Responses Scale is one of the most widely used measures of rumination, its two-factor structure remains controversial. Taking this into account, we aimed to test the RRS-10 two-factor invariance (Brazilian version) between different samples of women and to study its internal consistency and convergent validity. METHODS: A sample of 321 women (general population, n = 106; college students, n = 115; and medical population of patients with overweight and obesity, n = 100) participated in the study...
January 18, 2018: Psychology and Psychotherapy
https://www.readbyqxmd.com/read/29345623/affordable-and-accurate-large-scale-hybrid-functional-calculations-on-gpu-accelerated-supercomputers
#8
Laura E Ratcliff, Augustin Degomme, José A Flores-Livas, Stefan Goedecker, Luigi Genovese
Performing high accuracy hybrid functional calculations for condensed matter systems containing a large number of atoms is at present computationally very demanding or even out of reach if high quality basis sets are used. We present a highly optimized multiple GPU implementation of the exact exchange operator which allows one to perform fast hybrid functional density-functional theory calculations with systematic basis sets without additional approximations for up to a thousand atoms...
January 18, 2018: Journal of Physics. Condensed Matter: An Institute of Physics Journal
https://www.readbyqxmd.com/read/29345585/mandatory-reporting-of-coronary-artery-calcifications-incidentally-noted-on-chest-multi-detector-computed-tomography-a-multicentre-experience
#9
Salvatore Cappabianca, Maria Paola Belfiore, Alfonso Reginelli, Raffaella Capasso, Alessandra Del Prete, Mario Petrillo, Paola Mascia, Claudia Rossi, Francesco Romano, Massimo De Filippo, Michele Scialpi, Felice Gragnano, Paolo Calabro, Giuseppe Belfiore, Luca Brunese, Roberto Grassi, Antonio Rotondo
BACKGROUND Coronary artery calcifications (CACs) are associated with coronary atherosclerosis and cardiovascular (CV) events. In "non-cardiovascular" settings, CACs can be easily detected on chest multi-detector computed tomography (MDCT). Their evaluation may help to better stratify CV risk in the general population, especially for primary prevention. AIMS We retrospectively evaluated the relationship between CAC distribution and CV risk, determined by Framingham Risk Score (FRS), in a cohort of patients who underwent chest MDCT performed for several clinical indications...
January 16, 2018: Current Vascular Pharmacology
https://www.readbyqxmd.com/read/29345553/quality-and-variability-of-patient-directions-in-electronic-prescriptions-in-the-ambulatory-care-setting
#10
Yuze Yang, Stacy Ward-Charlerie, Ajit A Dhavle, Michael T Rupp, James Green
BACKGROUND: The prescriber's directions to the patient (Sig) are one of the most quality-sensitive components of a prescription order. Owing to their free-text format, the Sig data that are transmitted in electronic prescriptions (e-prescriptions) have the potential to produce interpretation challenges at receiving pharmacies that may threaten patient safety and also negatively affect medication labeling and patient counseling. Ensuring that all data transmitted in the e-prescription are complete and unambiguous is essential for minimizing disruptions in workflow at prescribers' offices and receiving pharmacies and optimizing the safety and effectiveness of patient care...
January 18, 2018: Journal of Managed Care & Specialty Pharmacy
https://www.readbyqxmd.com/read/29345516/association-between-weather-related-factors-and-cardiac-arrest-of-presumed-cardiac-etiology-a-prospective-observational-study-based-on-out-of-hospital-care-data
#11
Mario Hensel, Daniel Geppert, Jan F Kersten, Markus Stuhr, Jürgen Lorenz, Sebastian Wirtz, Thoralf Kerner
OBJECTIVE: The objective of this study was to determine the association between weather-related factors and out-of-hospital cardiac arrest (OHCA) of presumed cardiac etiology. METHODS: This was a prospective observational study performed in a prehospital setting. Data from the Emergency Medical Service in Hamburg (Germany) and data from the local weather station were evaluated over a 5-year period. Weather data (temperature, humidity, air pressure, wind speed) were obtained every minute and matched with the associated rescue mission data...
January 18, 2018: Prehospital Emergency Care
https://www.readbyqxmd.com/read/29345212/prioritising-action-to-accelerate-gender-equity-and-health-for-women-and-girls-microdata-analysis-of-47-countries
#12
Rachel Kidman, Jody Heymann
The Sustainable Development Goals set ambitious targets for health. Meeting such will require drastic improvements in the social conditions for women and girls. Understanding which social conditions have the greatest impact on health can help prioritise action, yet there is little comparative data. We use microdata from 338,580 women in 47 low- and middle-income countries to estimate the relative contributions of improved social determinants in bringing about maternal and child health gains over the past 20 years...
January 18, 2018: Global Public Health
https://www.readbyqxmd.com/read/29345124/disposable-morpho-menelaus-based-flexible-microfluidic-and-electronic-sensor-for-the-diagnosis-of-neurodegenerative-disease
#13
Zhenzhu He, Abdelrahman Elbaz, Bingbing Gao, Junning Zhang, Enben Su, Zhongze Gu
Rapid early disease prevention or precise diagnosis is almost impossible in low-resource settings. Natural ordered structures in nature have great potential for the development of ultrasensitive biosensors. Here, motivated by the unique structures and extraordinary functionalities of ordered structures in nature, a biosensor based on butterfly wings is presented. In this study, a flexible Morpho menelaus (M. menelaus) based wearable sensor is integrated with a microfluidic system and electronic networks to facilitate the diagnosis of neurodegenerative disease (ND)...
January 18, 2018: Advanced Healthcare Materials
https://www.readbyqxmd.com/read/29345073/improving-accuracy-of-genomic-prediction-in-brangus-cattle-by-adding-animals-with-imputed-low-density-snp-genotypes
#14
F B Lopes, X-L Wu, H Li, J Xu, T Perkins, J Genho, R Ferretti, R G Tait, S Bauck, G J M Rosa
Reliable genomic prediction of breeding values for quantitative traits requires the availability of sufficient number of animals with genotypes and phenotypes in the training set. As of 31 October 2016, there were 3,797 Brangus animals with genotypes and phenotypes. These Brangus animals were genotyped using different commercial SNP chips. Of them, the largest group consisted of 1,535 animals genotyped by the GGP-LDV4 SNP chip. The remaining 2,262 genotypes were imputed to the SNP content of the GGP-LDV4 chip, so that the number of animals available for training the genomic prediction models was more than doubled...
February 2018: Journal of Animal Breeding and Genetics, Zeitschrift Für Tierzüchtung und Züchtungsbiologie
https://www.readbyqxmd.com/read/29344883/discovering-altered-regulation-and-signaling-through-network-based-integration-of-transcriptomic-epigenomic-and-proteomic-tumor-data
#15
Amanda J Kedaigle, Ernest Fraenkel
With the extraordinary rise in available biological data, biologists and clinicians need unbiased tools for data integration in order to reach accurate, succinct conclusions. Network biology provides one such method for high-throughput data integration, but comes with its own set of algorithmic problems and needed expertise. We provide a step-by-step guide for using Omics Integrator, a software package designed for the integration of transcriptomic, epigenomic, and proteomic data. Omics Integrator can be found at http://fraenkel...
2018: Methods in Molecular Biology
https://www.readbyqxmd.com/read/29344476/acute-angle-closure-precipitated-by-hemorrhage-and-necrosis-of-a-large-uveal-melanoma-in-the-setting-of-systemic-immunomodulatory-therapy
#16
Chau M Pham, Krishna Kalyam, Bradley T Smith, Justin Floyd, John B Holds
Management of nonmetastatic uveal melanoma has been well studied and a large body of work has been published by the Collaborative Ocular Melanoma Study (amongst many others). Management of uveal melanoma that is found to be metastatic upon initial diagnosis, however, is less well defined. We report an interesting case of acute angle closure caused by necrosis and hemorrhage into a large uveal melanoma occurring shortly after initiation of immunomodulatory therapy with ipilimumab and nivolumab for metastatic disease...
November 2017: Ocular Oncology and Pathology
https://www.readbyqxmd.com/read/29344376/effectiveness-of-pharmacist-s-intervention-in-the-management-of-cardiovascular-diseases
#17
REVIEW
Stefano Omboni, Marina Caserini
The pharmacist may play a relevant role in primary and secondary prevention of cardiovascular diseases, mainly through patient education and counselling, drug safety management, medication review, monitoring and reconciliation, detection and control of specific cardiovascular risk factors (eg, blood pressure, blood glucose, serum lipids) and clinical outcomes. Systematic reviews of randomised controlled and observational studies have documented an improved control of hypertension, dyslipidaemia or diabetes, smoking cessation and reduced hospitalisation in patients with heart failure, following a pharmacist's intervention...
2018: Open Heart
https://www.readbyqxmd.com/read/29344121/a-five-gene-based-risk-score-with-high-prognostic-value-in-colorectal-cancer
#18
Yida Pan, Hongyang Zhang, Mingming Zhang, Jie Zhu, Jianghong Yu, Bangting Wang, Jigang Qiu, Jun Zhang
Colorectal cancer (CRC) is one of the most frequently occurring malignancies worldwide. The outcomes of patients with similar clinical symptoms or at similar pathological stages remain unpredictable. This inherent clinical diversity is most likely due to the genetic heterogeneity. The present study aimed to create a predicting tool to evaluate patient survival based on genetic profile. Firstly, three Gene Expression Omnibus (GEO) datasets (GSE9348, GSE44076 and GSE44861) were utilized to identify and validate differentially expressed genes (DEGs) in CRC...
December 2017: Oncology Letters
https://www.readbyqxmd.com/read/29343859/rate-after-effects-fail-to-transfer-cross-modally-evidence-for-distributed-sensory-timing-mechanisms
#19
Aysha Motala, James Heron, Paul V McGraw, Neil W Roach, David Whitaker
Accurate time perception is critical for a number of human behaviours, such as understanding speech and the appreciation of music. However, it remains unresolved whether sensory time perception is mediated by a central timing component regulating all senses, or by a set of distributed mechanisms, each dedicated to a single sensory modality and operating in a largely independent manner. To address this issue, we conducted a range of unimodal and cross-modal rate adaptation experiments, in order to establish the degree of specificity of classical after-effects of sensory adaptation...
January 17, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29343858/developmental-pathways-inferred-from-modularity-morphological-integration-and-fluctuating-asymmetry-patterns-in-the-human-face
#20
Mirsha Quinto-Sánchez, Francesc Muñoz-Muñoz, Jorge Gomez-Valdes, Celia Cintas, Pablo Navarro, Caio Cesar Silva de Cerqueira, Carolina Paschetta, Soledad de Azevedo, Virginia Ramallo, Victor Acuña-Alonzo, Kaustubh Adhikari, Macarena Fuentes-Guajardo, Tábita Hünemeier, Paola Everardo, Francisco de Avila, Claudia Jaramillo, Williams Arias, Carla Gallo, Giovani Poletti, Gabriel Bedoya, Maria Cátira Bortolini, Samuel Canizales-Quinteros, Francisco Rothhammer, Javier Rosique, Andres Ruiz-Linares, Rolando Gonzalez-Jose
Facial asymmetries are usually measured and interpreted as proxies to developmental noise. However, analyses focused on its developmental and genetic architecture are scarce. To advance on this topic, studies based on a comprehensive and simultaneous analysis of modularity, morphological integration and facial asymmetries including both phenotypic and genomic information are needed. Here we explore several modularity hypotheses on a sample of Latin American mestizos, in order to test if modularity and integration patterns differ across several genomic ancestry backgrounds...
January 17, 2018: Scientific Reports
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