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Temporal arteriitis

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https://www.readbyqxmd.com/read/29140981/wavelet-brain-angiography-suggests-arteriovenous-pulse-wave-phase-locking
#1
William E Butler
When a stroke volume of arterial blood arrives to the brain, the total blood volume in the bony cranium must remain constant as the proportions of arterial and venous blood vary, and by the end of the cardiac cycle an equivalent volume of venous blood must have been ejected. I hypothesize the brain to support this process by an extraluminally mediated exchange of information between its arterial and venous circulations. To test this I introduce wavelet angiography methods to resolve single moving vascular pulse waves (PWs) in the brain while simultaneously measuring brain pulse motion...
2017: PloS One
https://www.readbyqxmd.com/read/29134540/acute-connexin43-temporal-and-spatial-expression-in-response-to-ischemic-stroke
#2
Moises Freitas-Andrade, Jennifer She, John Bechberger, Christian C Naus, Wun Chey Sin
Connexin43 (Cx43) gap junctions expressed in astrocytes can significantly impact neuronal survival in stroke. However, little is known regarding Cx43 spatial and temporal expression during the initial stages of brain ischemia. Using immunohistochemistry and Western blot analysis, we examined Cx43 spatial and temporal expression as a function of neuronal injury within the first 24 h after permanent middle cerebral artery occlusion (pMCAO). Western blot analysis showed a significant increase in Cx43 protein expression in the core ischemic area at 2 and 3 h after pMCAO...
November 13, 2017: Journal of Cell Communication and Signaling
https://www.readbyqxmd.com/read/29131800/qualitative-and-quantitative-evaluation-of-dynamic-changes-in-non-culprit-coronary-atherosclerotic-lesion-morphology-a-longitudinal-oct-study
#3
Bu-Chun Zhang, Antonios Karanasos, Muthukaruppan Gnanadesigan, Johannes N van der Sijde, Nienke van Ditzhuijzen, Karen T Witberg, Jurgen Ligthart, Roberto Diletti, Robert-Jan van Geuns, Jouke Dijkstra, Felix Zijlstra, Gijs van Soest, Evelyn Regar
AIMS: There is limited in vivo evidence regarding the temporal evolution of non-culprit coronary plaque morphology. We evaluated changes in non-culprit plaque morphology over time by optical coherence tomography (OCT). METHODS AND RESULTS:  72 patients with 257 non-culprit segments with serial OCT studies were analyzed. Non-culprit 5mm-long coronary segments from the same imaged region were matched between baseline and follow-up. OCT plaque characterization including automated attenuation analysis was performed and changes over a median follow-up of 6...
November 14, 2017: EuroIntervention
https://www.readbyqxmd.com/read/29131549/diagnosis-of-kawasaki-disease
#4
Surjit Singh, Ankur Kumar Jindal, Rakesh Kumar Pilania
Kawasaki disease (KD) is a medium vessel vasculitis with predilection for coronary arteries. Due to lack of a reliable confirmatory laboratory test, the diagnosis of KD is based on a constellation of clinical findings that appear in a typical temporal sequence. These diagnostic criteria have been modified from time to time and the most recent guidelines have been proposed by the American Heart Association (AHA) in 2017. However, several children may have incomplete or atypical forms of KD and the diagnosis can often be difficult, especially in infants and young children...
November 13, 2017: International Journal of Rheumatic Diseases
https://www.readbyqxmd.com/read/29130616/emergency-extracorporeal-membrane-oxygenation-in-transcatheter-aortic-valve-implantation-a-two-center-experience-of-incidence-outcome-and-temporal-trends-from-2010-to-2015
#5
Teresa Trenkwalder, Costanza Pellegrini, Andreas Holzamer, Alois Philipp, Tobias Rheude, Jonathan Michel, Wibke Reinhard, Michael Joner, Albert M Kasel, Adnan Kastrati, Heribert Schunkert, Dierk Endemann, Kurt Debl, N Patrick Mayr, Michael Hilker, Christian Hengstenberg, Oliver Husser
BACKGROUND: Although the incidence of periprocedural complications has decreased in transcatheter aortic valve implantation (TAVI), life-threatening complications occur and emergency veno-arterial extracorporeal membrane oxygenation (vaECMO) can provide immediate circulatory stabilization. We report our two-center experience of vaECMO during life-threatening complications in TAVI. METHODS: From January 2010 to December 2015, 1,810 consecutive patients underwent TAVI at two centers...
November 11, 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/29125049/pseudoaneurysm-at-m3-of-the-middle-cerebral-artery-morphological-changes-on-serial-radiological-examinations
#6
Motohiro Nomura, Kentaro Mori, Issei Fukui, Kunio Yanagimoto, Hiroshi Shima, Naoki Muramatsu
A 20-year-old man presented with consciousness disturbance and hemiparesis, and computed tomography demonstrated subarachnoid and intracerebral hemorrhage. Angiography on admission demonstrated a slight irregularity of the middle cerebral artery (MCA) branch. Angiography on the 12th day showed a suspicious lesion at M3 of the left MCA. Angiography performed 24 days after the onset disclosed an aneurysm at M3. The aneurysm was trapped and resected after superficial temporal artery-MCA bypass. Pathological examinations revealed that this distal aneurysm was a pseudoaneurysm without vascular components in its dome...
January 1, 2017: Neuroradiology Journal
https://www.readbyqxmd.com/read/29120976/case-report-masquerading-large-vessel-giant-cell-arteritis
#7
Paul Jacquier, Raphael Wuarin, Carlo Chizzolini, Gabriele Thumann, Heimo Steffen, Argyrios Chronopoulos
SIGNIFICANCE: Large-vessel giant cell arteritis (GCA) can be a diagnostic dilemma for the eye care provider because it may not involve the typical cranial arteries. When any of its potential ocular complications are diagnosed, it is important to consider this unusual form of GCA. PURPOSE: To report an unusual ophthalmic presentation of large-vessel GCA with sequential bilateral anterior ischemic optic neuropathy and branch retinal artery occlusion. METHODS: A 65-year-old previously healthy woman experienced sequential bilateral anterior ischemic optic neuropathy with branch retinal artery occlusion in the absence of other signs and symptoms suggestive of cranial GCA...
November 9, 2017: Optometry and Vision Science: Official Publication of the American Academy of Optometry
https://www.readbyqxmd.com/read/29118201/inflow-of-oxygen-and-glucose-into-brain-tissue-induced-by-intravenous-norepinephrine-relationships-with-central-metabolic-and-peripheral-vascular-responses
#8
R Aaron Bola, Eugene A Kiyatkin
As an essential part of sympathetic activation that prepares the organism for "fight or flight," peripheral norepinephrine (NE) plays an important role in regulating cardiac activity and the tone of blood vessels, increasing blood flow to the heart and the brain and decreasing blood flow to the organs not as necessary for immediate survival. To assess whether this effect is applicable to the brain, we used high-speed amperometry to measure the changes in nucleus accumbens (NAc) levels of oxygen and glucose induced by intravenous (iv) injections of NE in awake, freely-moving rats...
November 8, 2017: Journal of Neurophysiology
https://www.readbyqxmd.com/read/29117962/lower-cardiac-index-levels-relate-to-lower-cerebral-blood-flow-in-older-adults
#9
Angela L Jefferson, Dandan Liu, Deepak K Gupta, Kimberly R Pechman, Jennifer M Watchmaker, Elizabeth A Gordon, Swati Rane, Susan P Bell, Lisa A Mendes, L Taylor Davis, Katherine A Gifford, Timothy J Hohman, Thomas J Wang, Manus J Donahue
OBJECTIVE: To assess cross-sectionally whether lower cardiac index relates to lower resting cerebral blood flow (CBF) and cerebrovascular reactivity (CVR) among older adults. METHODS: Vanderbilt Memory & Aging Project participants free of stroke, dementia, and heart failure were studied (n = 314, age 73 ± 7 years, 59% male, 39% with mild cognitive impairment). Cardiac index (liters per minute per meter squared) was quantified from echocardiography. Resting CBF (milliliters per 100 grams per minute) and hypercapnia-induced CVR were quantified from pseudo-continuous arterial spin-labeling MRI...
November 8, 2017: Neurology
https://www.readbyqxmd.com/read/29117499/preclinical-chorioamnionitis-dysregulates-cxcl1-cxcr2-signaling-throughout-the-placental-fetal-brain-axis
#10
REVIEW
Tracylyn R Yellowhair, Shahani Noor, Jessie R Maxwell, Christopher V Anstine, Akosua Y Oppong, Shenandoah Robinson, Erin D Milligan, Lauren L Jantzie
In the United States, perinatal brain injury (PBI) is a major cause of infant mortality and childhood disability. For a large proportion of infants with PBI, central nervous system (CNS) injury begins in utero with inflammation (chorioamnionitis/CHORIO) and/or hypoxia-ischemia. While studies show CHORIO contributes to preterm CNS injury and is also a common independent risk factor for brain injury in term infants, the molecular mechanisms mediating inflammation in the placental-fetal-brain axis that result in PBI remain a gap in knowledge...
November 5, 2017: Experimental Neurology
https://www.readbyqxmd.com/read/29117252/preclinical-4d-flow-magnetic-resonance-phase-contrast-imaging-of-the-murine-aortic-arch
#11
Moritz Braig, Jochen Leupold, Marius Menza, Maximilian Russe, Cheng-Wen Ko, Juergen Hennig, Dominik von Elverfeldt
PURPOSE: Cardiovascular diseases remain the number one death cause worldwide. Preclinical 4D flow phase contrast magnetic resonance imaging can provide substantial insights in the analysis of aortic pathophysiologies in various animal models. These insights may allow a better understanding of pathophysiologies, therapy monitoring, and can possibly be translated to humans. This study provides a framework to acquire the velocity field within the aortic arch. It analyses important flow values at different locations within the aortic arch...
2017: PloS One
https://www.readbyqxmd.com/read/29115560/identification-of-key-genes-transcription-factors-and-micrornas-involved-in-intracranial-aneurysm
#12
Liang Wei, Qi Wang, Yanfei Zhang, Cheng Yang, Hongxin Guan, Yiming Chen, Zhiyang Sun
Intracranial aneurysm (IA) is a devastating disease, the pathogenesis of which remains to be elucidated. The present study aimed to determine the molecular mechanism of IA and to identify potential therapeutic targets using bioinformatics analysis. The GSE54083 dataset, which includes data from patients with ruptured IA and superficial temporal artery controls, was downloaded from the Gene Expression Omnibus, and differentially expressed genes (DEGs) were identified in the ruptured IA samples using the limma package in R...
November 3, 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/29115100/efficacy-of-decompressive-craniectomy-in-the-management-of-intracranial-pressure-in-severe-traumatic-brain-injury
#13
John K Yue, Jonathan W Rick, Hansen Deng, Michael J Feldman, Ethan A Winkler
Traumatic brain injury (TBI) is a common cause of permanent disability for which clinical management remains suboptimal. Elevated intracranial pressure (ICP) is a common sequela following TBI leading to death and permanent disability if not properly managed. While clinicians often employ stepwise acute care algorithms to reduce ICP, a number of patients will fail medical management and may be considered for surgical decompression. Decompressive craniectomy (DC) involves removing a component of the bony skull to allow cerebral tissue expansion in order to reduce ICP...
November 7, 2017: Journal of Neurosurgical Sciences
https://www.readbyqxmd.com/read/29112741/atherosclerosis-as-a-potential-pitfall-in-the-diagnosis-of-giant-cell-arteritis
#14
Eugenio De Miguel, Luis M Beltran, Irene Monjo, Francesco Deodati, Wolfgang A Schmidt, Juan Garcia-Puig
Objectives: To explore whether the increase in the intima-media thickness (IMT) in arteriosclerotic disease correlates with the increase in the IMT in temporal arteries (TAs) and if that could mimic the US GCA halo sign. Methods: Consecutive patients ⩾50 years old with high vascular risk and without signs or symptoms of GCA were included. The carotid US IMT measurements were obtained using a standardized software radiofrequency-tracking technology. Colour Doppler US and grey-scale measurements of the IMT in the branches of both TAs were performed by a second sonographer using a 22 MHz probe...
November 2, 2017: Rheumatology
https://www.readbyqxmd.com/read/29111474/the-middle-temporal-artery-surgical-anatomy-and-exposure-for-cerebral-revascularization
#15
Roberto Rodriguez Rubio, Michael T Lawton, Olivia Kola, Halima Tabani, Sonia Yousef, Ali Tayebi Meybodi, Jan-Karl Burkhardt, Ivan El-Sayed, Arnau Benet
BACKGROUND: The middle temporal artery (MTA) is the proximal medial branch of the superficial temporal artery (STA), supplying the temporalis muscle along with deep temporal arteries. Its use in vascularized flaps for reconstructive and otologic procedures has been described, yet its potential use in neurosurgery is not studied. We report a novel technique for exposing the MTA and evaluated its characteristics for extracranial-intracranial (EC-IC) cerebrovascular bypass. METHODS: After a curvilinear frontotemporal incision in 10 cadaveric specimens, the STA was dissected from distal to proximal...
October 27, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/29110993/anterior-temporal-artery-to-posterior-cerebral-artery-bypass-for-revascularization-of-the-posterior-circulation-an-anatomical-study
#16
Kaan Yağmurlu, M Yashar S Kalani, Feres Chaddad-Neto, Orhun Mete Cevik, Baran Bozkurt, Evgenii Belykh, Hugo Leonardo Doria-Netto, Andrew W Grande, Mark C Preul, Robert F Spetzler
We describe a novel intracranial-to-intracranial bypass technique between the anterior temporal artery and the posterior cerebral artery for revascularization of the posterior circulation. Four formalin-fixed human heads were examined to demonstrate the detailed anatomy of the middle cerebral artery and the posterior cerebral artery, and to illustrate the step-by-step bypass procedure. The anterior temporal artery, a branch of the middle cerebral artery, can be anastomosed to the P2 segment of the posterior cerebral artery as an alternative to extracranial bypass donor segments for treatment of complex aneurysms requiring revascularization...
October 27, 2017: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/29106745/demonstration-of-velocity-selective-myocardial-arterial-spin-labeling-perfusion-imaging-in-humans
#17
Terrence R Jao, Krishna S Nayak
PURPOSE: Transit delay is a potential source of error in cardiac arterial spin-labeled (ASL) in heart failure or with collateral circulation. This study demonstrates the feasibility of using transit delay insensitive velocity selective ASL and compares its performance with flow-sensitive alternating inversion recovery (FAIR) ASL. METHODS: Velocity selective labeling was achieved using an adiabatic BIR8 preparation. FAIR and velocity-selective ASL (VSASL) with various velocity cutoffs (VC  = 10-40 cm/s) and labeling directions (anterior-posterior X, lateral-septal Y, and apical-basal Z) were carried out in 10 healthy volunteers (1F/9M age 23-30 y)...
November 6, 2017: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/29105383/hypoxia-and-placental-development
#18
REVIEW
Michael J Soares, Khursheed Iqbal, Keisuke Kozai
Hemochorial placentation is orchestrated through highly regulated temporal and spatial decisions governing the fate of trophoblast stem/progenitor cells. Trophoblast cell acquisition of specializations facilitating invasion and uterine spiral artery remodeling is a labile process, sensitive to the environment, and represents a process that is vulnerable to dysmorphogenesis in pathologic states. Hypoxia is a signal guiding placental development, and molecular mechanisms directing cellular adaptations to low oxygen tension are integral to trophoblast cell differentiation and placentation...
October 16, 2017: Birth defects research
https://www.readbyqxmd.com/read/29101571/control-of-inferior-vena-cava-injury-during-laparoscopic-surgery-using-a-double-balloon-equipped-central-venous-catheter-proof-of-concept-in-a-live-porcine-model
#19
Yukio Iwashita, Hiroki Uchida, Hiroomi Takayama, Michihiro Ichimanda, Katsuya Taniguchi, Hideki Kiguchi, Tetsumi Sakaguchi, Hajime Fujishima, Kunihiro Saga, Kazuhiro Tada, Takao Hara, Kiminori Watanabe, Teijiro Hirashita, Yuichi Endo, Masayuki Ohta, Masafumi Inomata
BACKGROUND: Iatrogenic inferior vena cava (IVC) injury is a rare but potentially life-threatening complication during laparoscopic surgery. This experimental study aimed to assess the hemostatic ability of a new device, double balloon-equipped central venous (DB-CV) catheter, for IVC injury. METHODS: The DB-CV catheter comprises a triple-lumen sphincterotome combined with two dilating balloons having a diameter of 25 mm. The experimental procedures were performed in five pigs...
November 3, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/29101422/biomarkers-of-inflammation-and-endothelial-dysfunction-as-predictors-of-pulse-pressure-and-incident-hypertension-in-type-1-diabetes-a-20%C3%A2-year-life-course-study-in-an-inception-cohort
#20
Isabel Ferreira, Peter Hovind, Casper G Schalkwijk, Hans-Henrik Parving, Coen D A Stehouwer, Peter Rossing
AIMS/HYPOTHESIS: Vascular inflammation and endothelial dysfunction are thought to contribute to arterial stiffening and hypertension. This study aims to test this hypothesis with longitudinal data in the context of type 1 diabetes. METHODS: We investigated, in an inception cohort of 277 individuals with type 1 diabetes, the course, tracking and temporal inter-relationships of BP, specifically pulse pressure (a marker of arterial stiffening) and hypertension, and the following biomarkers of systemic and vascular inflammation/endothelial dysfunction: C-reactive protein (CRP), soluble intracellular adhesion molecule-1 (sICAM-1), soluble vascular cellular adhesion molecule-1 (sVCAM-1) and soluble E-selectin (sE-selectin)...
November 3, 2017: Diabetologia
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