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https://www.readbyqxmd.com/read/29793097/quantitative-assessment-of-placental-perfusion-by-three-dimensional-power-doppler-ultrasound-for-twins-with-selective-intrauterine-growth-restriction-in-one-twin
#1
Wei Sun, Jingyi Liu, Ying Zhang, Ailu Cai, Zeyu Yang, Yili Zhao, Yu Wang, Zhe Cao, Qiuju Wei
OBJECTIVE: We quantitatively assessed placental perfusion using three-dimensional (3D) power Doppler ultrasound for twins with selective intrauterine growth restriction (sIUGR) in one twin. STUDY DESIGN: A prospective cross-sectional study was performed for 104 normal monochorionic diamniotic twins and 30 twins with sIUGR. Twins with sIUGR were divided into two groups: in group I (19 twins), both fetuses had continuous forward end-diastolic blood flow in the umbilical artery; in group II (11 twins), the smaller fetus had a loss or a reverse end-diastolic blood flow in the umbilical artery, but the larger fetus had continuous forward end-diastolic blood flow...
May 17, 2018: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/29793046/validation-of-the-revised-pam-score-in-patients-with-aml-undergoing-allogeneic-hematopoietic-stem-cell-transplantation
#2
Jan M Middeke, Frederike Kollinger, Henning Baldauf, Friedrich Stölzel, Martin Wermke, Malte von Bonin, Katja Sockel, Cornelia S Link, Raphael Teipel, Christoph Röllig, Christian Thiede, Uwe Platzbecker, Gerhard Ehninger, Martin Bornhäuser, Johannes Schetelig
PURPOSE: Despite recent advances, allogeneic hematopoietic stem cell transplantation (alloHSCT) continues to be accompanied by a high rate of morbidity and mortality. Several scores have been developed to predict outcome after HSCT. The PAM score has been recently revised, and utilizes information on patient age, donor type, disease risk, cytomegalovirus (CMV) serostatus of patients and donors, and the forced expiratory volume in one second (FEV1). The aim of this study was to analyze the predictive power of the PAM score in an independent, large cohort of acute myeloid leukemia (AML) patients...
May 21, 2018: Biology of Blood and Marrow Transplantation
https://www.readbyqxmd.com/read/29792070/chondral-delamination-of-fresh-osteochondral-allografts-after-implantation-in-the-knee-a-matched-cohort-analysis
#3
Ryan C Rauck, Dean Wang, Matthew Tao, Riley J Williams
Introduction Delamination of the chondral surface of an osteochondral allograft (OCA) from the underlying cancellous bone has been described as a mode of failure after implantation in the knee. Our hypothesis was that increased storage time of the OCA is associated with increased risk of graft delamination after implantation. Methods Prospective data on 13 patients with evidence of OCA delamination identified on magnetic resonance imaging or during subsequent surgery from 2000 to 2015 were reviewed. A cohort of 33 patients without evidence of graft delamination were then matched to the delamination group based on recipient age, sex, body mass index (BMI), and chondral defect location...
May 1, 2018: Cartilage
https://www.readbyqxmd.com/read/29791905/disparities-in-chronic-kidney-disease-prevalence-among-males-and-females-in-195-countries-analysis-of-the-global-burden-of-disease-2016-study
#4
Boris Bikbov, Norberto Perico, Giuseppe Remuzzi
BACKGROUND: Chronic kidney disease (CKD) imposes a substantial burden on health care systems. There are some especially vulnerable groups with a high CKD burden, one of which is women. We performed an analysis of gender disparities in the prevalence of all CKD stages and renal replacement therapy (defined as impaired kidney function [IKF]) in 195 countries. METHODS: We used estimates produced by the Global Burden of Disease (GBD) Study 2016 revision using a Bayesian-regression analytic tool, DisMoD-MR 2...
May 23, 2018: Nephron
https://www.readbyqxmd.com/read/29791867/longitudinal-assessment-of-chemotherapy-induced-changes-in-brain-and-cognitive-functioning-a-systematic-review
#5
REVIEW
Mingmei Li, Karen Caeyenberghs
In addition to the burden of a life-threatening diagnosis, cancer patients are struggling with adverse side-effects from cancer treatment. Chemotherapy has been linked to an array of cognitive impairments and alterations in brain structure and function ("chemobrain"). In this review, we summarized the existing evidence that evaluate the changes in cognitive functioning and brain with chemotherapy, as assessed using structural and functional MRI-based techniques in a longitudinal design. This review followed the latest PRISMA guidelines using Embase, Medline, PsychINFO, Scopus, and Web of Science databases with date restrictions from 2012-2017...
May 20, 2018: Neuroscience and Biobehavioral Reviews
https://www.readbyqxmd.com/read/29791337/applicability-of-a-model-with-average-inversion-level-to-a-cladding-pumped-multicore-erbium-doped-fiber-amplifier
#6
Hirotaka Ono, Makoto Yamada
This paper investigates the applicability of a model of a cladding-pumped multicore erbium-doped fiber amplifier (CP-MC-EDFA) that employs the average inversion level of an erbium ion. The model is modified to include the effects of multiple cores for modifications of the background loss coefficient of the pump light. The model is validated experimentally by measurements of the pump power, gain transient, and intercore cross-gain modulation of a cladding-pumped 12-core EDFA in which the pump light is uniformly distributed in the inner cladding...
May 10, 2018: Applied Optics
https://www.readbyqxmd.com/read/29791260/assessment-of-the-power-required-for-optimal-use-of-current-inhalation-devices
#7
Gerhard Pohlmann, Jens M Hohlfeld, Peter Haidl, Jelena Pankalla, Rolf Michael Cloes
BACKGROUND: Inhalation of medications is the cornerstone in the treatment of patients with lung diseases. A variety of inhalation devices exists and each device has specific requirements to achieve optimum inhalation of the drug. The goal of this study was to establish a clear overview on performance requirements of standard inhalation devices that should be met by the patient's breathing power and to develop a new method to measure the individual performance data. MATERIALS AND METHODS: An optimum and still acceptable required breathing power (P in watts) was calculated for each device with the aid of individual device flow rates (determined by a literature search) and the flow resistances (by measuring the pressure drop over the different inhalation devices)...
May 23, 2018: Journal of Aerosol Medicine and Pulmonary Drug Delivery
https://www.readbyqxmd.com/read/29791147/investigations-of-the-magnetic-and-spectroscopic-properties-of-v-iii-and-v-iv-complexes
#8
Casey Van Stappen, Dimitrios Maganas, Serena DeBeer, Eckhard Bill, Frank Neese
Herein, we utilize a variety of physical methods including magnetometry (SQUID), electron paramagnetic resonance (EPR), and magnetic circular dichroism (MCD), in conjunction with high-level ab initio theory to probe both the ground and ligand-field excited electronic states of a series of V(IV) ( S = 1 /2 ) and V(III) ( S = 1) molecular complexes. The ligand fields of the central metal ions are analyzed with the aid of ab initio ligand-field theory (AILFT), which allows for a chemically meaningful interpretation of multireference electronic structure calculations at the level of the complete-active-space self-consistent field with second-order N-electron valence perturbation theory...
May 23, 2018: Inorganic Chemistry
https://www.readbyqxmd.com/read/29788776/lenstar%C3%A2-ls-900-vs-pentacam%C3%A2-axl-comparative-study-of-ocular-biometric-measurements-and-intraocular-lens-power-calculation
#9
Joana Maria Mendes Pereira, Arminda Neves, Pedro Alfaiate, Mónica Santos, Henrique Aragão, João C Sousa
PURPOSE: Comparison of biometric measurements and calculation of intraocular lens with a new biometer (Pentacam®-AXL, Oculus, Germany) and a reference biometer (Lenstar LS 900®, Haag-Streit AG, Switzerland), in order to assess the agreement between these two devices. SETTING: Centro Hospitalar de Leiria, Portugal Materials and methods: Prospective, institutional study, in which measurements of axial length, anterior chamber depth from the corneal epithelium and endothelium to the anterior surface of the lens (anterior chamber depth ext and anterior chamber depth int), central corneal thickness and keratometry readings of the flattest and steepest meridians (K1 and K2) were obtained with the two systems...
May 1, 2018: European Journal of Ophthalmology
https://www.readbyqxmd.com/read/29788552/an-analytical-dose-averaged-let-calculation-algorithm-considering-the-off-axis-let-enhancement-by-secondary-protons-for-spot-scanning-proton-therapy
#10
Shusuke Hirayama, Taeko Matsuura, Ueda Hideaki, Yusuke Fujii, Takaaki Fujii, Seishin Takao, Naoki Miyamoto, Shinichi Shimizu, Rintaro Fujimoto, Kikuo Umegaki, Hiroki Shirato
PURPOSE: To evaluate the biological effects of proton beams as part of daily clinical routine, fast and accurate calculation of dose-averaged linear energy transfer (LETd ) is required. In this study, we have developed the analytical LETd calculation method based on the pencil-beam algorithm (PBA) considering the off-axis enhancement by secondary protons. This algorithm (PBA-dLET) was then validated using Monte Carlo simulation (MCS) results. METHODS: In PBA-dLET, LET values were assigned separately for each individual dose kernel based on the PBA...
May 22, 2018: Medical Physics
https://www.readbyqxmd.com/read/29787558/a-new-weighted-injury-severity-scoring-system-better-predictive-power-for-pediatric-trauma-mortality
#11
Junxin Shi, Jiabin Shen, Sarah Caupp, Angela Wang, Kathryn E Nuss, Brian Kenney, Krista K Wheeler, Bo Lu, Henry Xiang
BACKGROUND: An accurate injury severity measurement is essential for the evaluation of pediatric trauma care and outcome research. The traditional Injury Severity Score (ISS) does not consider the differential risks of the Abbreviated Injury Scale (AIS) from different body regions nor is it pediatric specific. The objective of this study was to develop a weighted injury severity scoring (wISS) system for pediatric blunt trauma patients with better predictive power than ISS. METHODS: Based on the association between mortality and AIS from each of the six ISS body regions, we generated different weights for the component AIS scores used in the calculation of ISS...
May 2, 2018: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/29787382/machine-learning-based-dual-energy-ct-parametric-mapping
#12
Kuan-Hao Su, Jung-Wen Kuo, David W Jordan, Steven Van Hedent, Paul Klahr, Zhouping Wei, Rose Al Helo, Fan Liang, Pengjiang Qian, Gisele C Pereira, Negin Rassouli, Robert C Gilkeson, Bryan J Traughber, Chee-Wai Cheng, Raymond F Muzic
The aim is to develop and evaluate machine learning methods for generating quantitative parametric maps of effective atomic number (Z<sub>eff</sub>), relative electron density (ρ<sub>e</sub>), mean excitation energy (<i>I<sub>x</sub></i>), and relative stopping power (RSP) from clinical dual-energy CT data. The maps could be used for material identification and radiation dose calculation. 
 Machine learning methods of historical centroid (HC), random forest (RF), and artificial neural networks (ANN) were used to learn the relationship between dual-energy CT input data and ideal output parametric maps calculated for phantoms from the known compositions of 13 tissue substitutes...
May 22, 2018: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/29786621/a-resisted-sprint-improves-rate-of-force-development-during-a-20-m-sprint-in-athletes
#13
Gerald T Mangine, Kevin Huet, Cassie Williamson, Emily Bechke, Paul Serafini, David Bender, John Hudy, Jeremy Townsend
Mangine, GT, Huet, K, Williamson, C, Bechke, E, Serafini, P, Bender, D, Hudy, J, and Townsend, J. A resisted sprint improves rate of force development during a 20-m sprint in athletes. J Strength Cond Res 32(6): 1531-1537, 2018-This study examined the effect of a resisted sprint on 20-m sprinting kinetics. After a standardized warm-up, 23 (male = 10, female = 13) Division I basketball players completed 3 maximal 20-m sprint trials while tethered to a robotic resistance device. The first sprint (S1) used the minimal, necessary resistance (1 kg) to detect peak (PK) and average (AVG) sprinting power (P), velocity (V), and force (F); peak rate of force production (RFD) was also calculated...
June 2018: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/29786044/prognostic-value-of-model-for-end-stage-liver-disease-incorporating-with-serum-sodium-score-for-development-of-acute-kidney-injury-after-liver-transplantation
#14
Yuan Cheng, Guo-Qing Wei, Qiu-Cheng Cai, Yi Jiang, Ai-Ping Wu
Background: Contribution of model for end-stage liver disease incorporating with serum sodium (MELD-Na) score in predicting acute kidney injury (AKI) after orthotopic liver transplantation (OLT) is yet to be identified. This study assessed the prognostic value of MELD-Na score for the development of AKI following OLT. Methods: Preoperative and surgery-related variables of 321 adult end-stage liver disease patients who underwent OLT in Fuzhou General Hospital were collected...
June 5, 2018: Chinese Medical Journal
https://www.readbyqxmd.com/read/29785693/massive-transfusion-the-revised-assessment-of-bleeding-and-transfusion-rabt-score
#15
Bellal Joseph, Muhammad Khan, Michael Truitt, Faisal Jehan, Narong Kulvatunyou, Asad Azim, Arpana Jain, Muhammad Zeeshan, Andrew Tang, Terence O'Keeffe
BACKGROUND: Massive transfusion (MT) is a lifesaving treatment for trauma patients with hemorrhagic shock, assessed by Assessment of Blood Consumption (ABC) Score based on mechanism of injury, systolic blood pressure (SBP), tachycardia, and FAST exam. The aim of this study was to assess the performance of ABC score by replacing hypotension and tachycardia; with Shock Index (SI) > 1.0 and including pelvic fractures. METHODS: We performed a 2-year (2014-2015) analysis of all high-level trauma activations and excluded patients dead on arrival...
May 21, 2018: World Journal of Surgery
https://www.readbyqxmd.com/read/29785435/assessing-the-performance-of-mm-pbsa-and-mm-gbsa-methods-7-entropy-effects-on-the-performance-of-end-point-binding-free-energy-calculation-approaches
#16
Huiyong Sun, Lili Duan, Fu Chen, Hui Liu, Zhe Wang, Peichen Pan, Feng Zhu, John Z H Zhang, Tingjun Hou
Entropy effects play an important role in drug-target interactions, but the entropic contribution to ligand-binding affinity is often neglected by end-point binding free energy calculation methods, such as MM/GBSA and MM/PBSA, due to the expensive computational cost of normal mode analysis (NMA). Here, we systematically investigated entropy effects on the prediction power of MM/GBSA and MM/PBSA using >1500 protein-ligand systems and six representative AMBER force fields. Two computationally efficient methods, including NMA based on truncated structures and the interaction entropy approach, were used to estimate the entropic contributions to ligand-target binding free energies...
May 22, 2018: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/29784891/predicting-physical-activity-behavior-in-african-american-females-using-multi-theory-model
#17
Traci Hayes, Vinayak K Nahar, Manoj Sharma
BACKGROUND: Despite physical activity having several benefits, a considerable number of Americans do not engage in sufficient exercise. Among the high-risk groups are African American women. A recent theory, multi theory model (MTM) for health behavior change can be used to develop effective interventions. The objective of this research was to test MTM in its ability to predict physical activity behavior in African American women. STUDY DESIGN: A cross-sectional study...
April 12, 2018: Journal of Research in Health Sciences
https://www.readbyqxmd.com/read/29784602/molecular-methods-for-diversity-assessment-among-xanthomonads-of-bulgarian-and-macedonian-pepper
#18
Taca Vancheva, Mariya Stoyanova, Elena Tasheva-Terzieva, Nevena Bogatzevska, Penka Moncheva
Bacterial spot is an important disease of pepper in Bulgaria and Macedonia. For characterization of Xanthomonas species associated with bacterial spot, 161 strains were collected from various field pepper-growing regions. Among them, 131 strains were identified as Xanthomonas euvesicatoria and 30 as Xanthomonas vesicatoria using species-specific primers and polymerase chain reaction followed by restriction fragment length polymorphism analysis. To assess the genetic diversity of the strains, two methods (Random Amplified Polymorphic DNA and Repetitive Element Palindromic-Polymerase Chain Reaction) were applied...
May 3, 2018: Brazilian Journal of Microbiology: [publication of the Brazilian Society for Microbiology]
https://www.readbyqxmd.com/read/29782678/nanoparticle-enhanced-silver-nanowire-plasmonic-electrodes-for-high-performance-organic-optoelectronic-devices
#19
Taehyo Kim, Saewon Kang, Jungwoo Heo, Seungse Cho, Jae Won Kim, Ayoung Choe, Bright Walker, Ravi Shanker, Hyunhyub Ko, Jin Young Kim
Improved performance in plasmonic organic solar cells (OSCs) and organic light-emitting diodes (OLEDs) via strong plasmon-coupling effects generated by aligned silver nanowire (AgNW) transparent electrodes decorated with core-shell silver-silica nanoparticles (Ag@SiO2 NPs) is demonstrated. NP-enhanced plasmonic AgNW (Ag@SiO2 NP-AgNW) electrodes enable substantially enhanced radiative emission and light absorption efficiency due to strong hybridized plasmon coupling between localized surface plasmons (LSPs) and propagating surface plasmon polaritons (SPPs) modes, which leads to improved device performance in organic optoelectronic devices (OODs)...
May 21, 2018: Advanced Materials
https://www.readbyqxmd.com/read/29780410/quantification-of-upper-limb-motor-recovery-and-eeg-power-changes-after-robot-assisted-bilateral-arm-training-in-chronic-stroke-patients-a-prospective-pilot-study
#20
Marialuisa Gandolfi, Emanuela Formaggio, Christian Geroin, Silvia Francesca Storti, Ilaria Boscolo Galazzo, Marta Bortolami, Leopold Saltuari, Alessandro Picelli, Andreas Waldner, Paolo Manganotti, Nicola Smania
Background: Bilateral arm training (BAT) has shown promise in expediting progress toward upper limb recovery in chronic stroke patients, but its neural correlates are poorly understood. Objective: To evaluate changes in upper limb function and EEG power after a robot-assisted BAT in chronic stroke patients. Methods: In a within-subject design, seven right-handed chronic stroke patients with upper limb paresis received 21 sessions (3 days/week) of the robot-assisted BAT...
2018: Neural Plasticity
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