keyword
https://read.qxmd.com/read/38512510/optical-coherence-tomography-angiography-suggests-choriocapillaris-perfusion-deficit-as-etiology-of-acute-macular-neuroretinopathy
#21
JOURNAL ARTICLE
Claus von der Burchard, Arved Gruben, Johann Roider
PURPOSE: Acute macular neuroretinopathy (AMN) can cause sudden-onset and permanent scotoma in healthy young patients. Analysis of optical coherence tomography (OCT) and OCT angiography (OCTA) of AMN patients may provide insights into disease mechanism. METHODS: We conducted a retrospective study of consecutive SARS-Cov-2-related AMN patients that presented in our clinic between Jan 1st, 2022, and April 30th, 2023, within 30 days of symptom onset. Retinal vessel area density (VAD) of AMN lesions in OCTA was quantified and compared to an adjacent tissue control (ATC)...
March 21, 2024: Graefe's Archive for Clinical and Experimental Ophthalmology
https://read.qxmd.com/read/38508440/application-of-optical-coherence-tomography-angiography-in-the-assessment-of-diabetic-macular-edema-staging-and-laser-photocoagulation-efficacy
#22
JOURNAL ARTICLE
Wei-Na Fu, Yan Du, Zhi-Yong Gong
OBJECTIVE: This study aimed to analyze the effect of optical coherence tomography angiography (OCTA) on diabetic macular edema (DME) staging and assess the efficacy of laser photocoagulation. METHODS: Eighty-six patients (141 eyes) with suspected DME who visited our hospital from August 2019 to March 2022 were selected and underwent fundus angiography and OCTA. The two examination methods were compared in terms of their efficacy in macular edema staging. Subsequently, the sensitivity, specificity, accuracy, positive predictive value, and negative predictive value of OCTA in diagnosing DME were assessed using fundus angiography as the gold standard...
March 18, 2024: Photodiagnosis and Photodynamic Therapy
https://read.qxmd.com/read/38499344/new-proposal-for-a-multimodal-imaging-approach-for-the-subclinical-detection-of-hydroxychloroquine-induced-retinal-toxicity-in-patients-with-systemic-lupus-erythematosus
#23
JOURNAL ARTICLE
Olga Araújo, Ricardo P Casaroli-Marano, José Hernández-Rodríguez, Marc Figueras-Roca, Vanesa Budi, Montse Morató, Halbert Hernández-Negrín, José Ríos, Alfredo Adan, Gerard Espinosa, Laura Pelegrín, Ricard Cervera
OBJECTIVE: To compare multimodal structural and functional diagnostic methods in patients with systemic lupus erythematosus (SLE) treated with hydroxychloroquine, to identify the best complementary approach for detecting subclinical retinal toxicity. METHODS: A cross-sectional, unicentric study was conducted on patients with SLE treated with hydroxychloroquine. Each patient underwent a comprehensive ophthalmic evaluation, comprising structural tests (spectral-domain optical coherence tomography (SD-OCT), en face OCT, en face OCT angiography (OCTA), fundus autofluorescence (FAF)) and functional tests (automated perimetry for visual field (VF) testing, multifocal electroretinography (mfERG))...
March 18, 2024: BMJ Open Ophthalmology
https://read.qxmd.com/read/38499321/acute-spontaneous-vortex-vein-occlusion-clinical-features-multimodal-imaging-and-natural-course
#24
JOURNAL ARTICLE
Kang Xue, Fengxi Meng, Hui Ren, Han Yue, Lin Jonathan He, Ruiqi Ma, Xintong Lin, Jiang Qian, Jie Guo
AIMS: To describe the clinical features, multimodal imaging, treatments and natural course of acute spontaneous vortex vein occlusion. METHODS: Clinical data were collected on nine patients with acute vortex vein occlusion. The symptoms and signs, multimodal imaging, treatments and follow-up results were summarised. RESULTS: Six patients (66.7%) were men and three (33.3%) were women. The mean age was 47.8±15.4 years. Patients were initially misdiagnosed as having choroidal tumour (66...
March 18, 2024: British Journal of Ophthalmology
https://read.qxmd.com/read/38498946/naringenin-roled-octacalcium-phosphate-reinforced-with-polyvinyl-alcohol-composite-for-sarcoma-affected-bone-repair
#25
JOURNAL ARTICLE
Qiang Lin, Xuzheng Wang, Bin Jia, Minghua Bai, Kunzheng Wang
Osteosarcoma is a rare cancer affecting disease for children and young adults; complete healing from this condition is quite difficult. Recently, new regeneration materials have been preferred, including natural compound companied implants for affected bone repair, and it is effectively used to treat osteosarcoma disease. Hence, Octa calcium phosphate (OCP) reinforced with poly (vinyl alcohol) (PVA) and oleic acid (OA) with Naringenin (NRG) composite was prepared and studied to cure the sarcoma affected bone...
March 18, 2024: Biomedical Materials
https://read.qxmd.com/read/38489765/deep-learning-for-automatic-prediction-of-early-activation-of-treatment-na%C3%A3-ve-non-exudative-mnvs-in-amd
#26
JOURNAL ARTICLE
Emanuele Crincoli, Fiammetta Catania, Riccardo Sacconi, Nicolò Ribarich, Silvia Ferrara, Mariacristina Parravano, Eliana Costanzo, Giuseppe Querques
BACKGROUND: Around 30% of non-exudative macular neovascularizations(NE-MNVs) exudate within 2 years from diagnosis in patients with age-related macular degeneration(AMD).The aim of the study is to develop a deep learning classifier based on optical coherence tomography(OCT) and OCT angiography(OCTA) to identify NE-MNVs at risk of exudation. METHODS: AMD patients showing OCTA and fluorescein angiography (FA) documented NE-MNV with a 2-years minimum imaging follow-up were retrospectively selected...
March 14, 2024: Retina
https://read.qxmd.com/read/38487802/drac-2022-a-public-benchmark-for-diabetic-retinopathy-analysis-on-ultra-wide-optical-coherence-tomography-angiography-images
#27
JOURNAL ARTICLE
Bo Qian, Hao Chen, Xiangning Wang, Zhouyu Guan, Tingyao Li, Yixiao Jin, Yilan Wu, Yang Wen, Haoxuan Che, Gitaek Kwon, Jaeyoung Kim, Sungjin Choi, Seoyoung Shin, Felix Krause, Markus Unterdechler, Junlin Hou, Rui Feng, Yihao Li, Mostafa El Habib Daho, Dawei Yang, Qiang Wu, Ping Zhang, Xiaokang Yang, Yiyu Cai, Gavin Siew Wei Tan, Carol Y Cheung, Weiping Jia, Huating Li, Yih Chung Tham, Tien Yin Wong, Bin Sheng
We described a challenge named "DRAC - Diabetic Retinopathy Analysis Challenge" in conjunction with the 25th International Conference on Medical Image Computing and Computer Assisted Intervention (MICCAI 2022). Within this challenge, we provided the DRAC datset, an ultra-wide optical coherence tomography angiography (UW-OCTA) dataset (1,103 images), addressing three primary clinical tasks: diabetic retinopathy (DR) lesion segmentation, image quality assessment, and DR grading. The scientific community responded positively to the challenge, with 11, 12, and 13 teams submitting different solutions for these three tasks, respectively...
March 8, 2024: Patterns
https://read.qxmd.com/read/38487359/optical-coherence-tomography-angiographic-follow-up-in-a-case-of-subacute-sclerosing-panencephalitis-and-unilateral-necrotising-retinitis
#28
Seher Köksaldı, Rahmi Tumay Ala, Ibrahim Oztura, Emre Emirbayer, Gulden Akdal, Sinan Emre, Ilknur Tugal-Tutkun, Ali Osman Saatci
We present a 20-year-old woman who was diagnosed with subacute sclerosing panencephalitis (SSPE) 20 months after presenting with unilateral retinitis. At presentation, the patient had two inferotemporal macular lesions in her left eye. Corresponding to these areas, optical coherence tomography (OCT) showed hyporeflective spaces with loss of nearly all of the retinal layers. OCT-angiography (OCTA) demonstrated some flow deficit areas with a reduction in the vessel density. Her serum measles antibody titre was high (IgG >5000...
2024: Neuro-ophthalmology
https://read.qxmd.com/read/38487148/optical-coherence-tomography-angiography-changes-in-patients-diagnosed-with-acute-coronary-syndrome-a-systematic-review-and-meta-analysis
#29
REVIEW
Anna Maria Sideri, Dimitra Mitsopoulou, Stylianos A Kandarakis, Andreas Katsimpris, Menelaos Kanakis, Aristotelis Karamaounas, Dimitrios Brouzas, Petros Petrou, Evangelia Papakonstantinou, Konstantinos Droutsas, Georgios Giannopoulos, Ilias Georgalas
We conducted a systematic review and meta-analysis to assess the association between optical coherence tomography angiography (OCTA) parameters and acute coronary syndrome (ACS). Two independent reviewers searched the electronic databases (MEDLINE (Medical Literature Analysis and Retrieval System Online), Scopus, Embase (Excerpta Medica Database), Cochrane Library, ClinicalTrials.gov, and World Health Organization International Clinical Trials Registry Platform) from inception until April 2023. According to the inclusion criteria of this review, eligible were observational studies, randomized control trials, and registry/database studies that included the eyes of adult ACS patients and assessed OCTA parameters within the macula...
February 2024: Curēus
https://read.qxmd.com/read/38484716/comparison-of-changes-in-retinal-vascular-parameters-and-density-in-patients-with-moyamoya-disease-a-retrospective-study
#30
JOURNAL ARTICLE
Xijuan Wang, Ying Meng, Dan Song, Cunxin Tan, Guanzheng Wang, Bin Lv, Yuan Ni, Guotong Xie, Ting Cui, Yan Zhang, Yaqian Niu, Chengxia Zhang, Guangfeng Liu
OBJECTIVE: This study aims to compare retinal vascular parameters and density in patients with Moyamoya disease using the optical coherence tomography angiography. PATIENTS AND METHODS: This clinical trial totally enrolls 78 eyes from 39 participants, and all these patients with Moyamoya disease (N=13) are set as experimental group and participants with health who matched with age and gender are considered as the control group (N=26). Then all these participants receive Optical coherence tomography angiography detection...
March 14, 2024: Ophthalmic Research
https://read.qxmd.com/read/38483688/can-objective-parameters-in-optical-coherence-tomography-be-useful-markers-in-the-treatment-and-follow-up-of-type-1-and-type-2-macular-neovascularizations-related-to-neovascular-age-related-macular-degeneration
#31
JOURNAL ARTICLE
Osman Özen, Ayşe Gül Koçak Altıntaş
PURPOSE: The aim of this study was to compare the responses of type 1 and type 2 macular neovascularizations (MNV) caused by neovascular type age-related macular degeneration (n-AMD) to intravitreal anti-vascular endothelial growth factor (VEGF) treatments using quantitative parameters determined by optical coherence tomography (OCT). Additionally, it was also intended to assess the connections between these quantitative parameters and changes in best-corrected visual acuity (BCVA) and the number of intravitreal anti-VEGF injections required within a year...
March 14, 2024: International Ophthalmology
https://read.qxmd.com/read/38481443/effect-of-mydriasis-on-macular-and-peripapillary-metrics-in-swept-source-optical-coherence-tomography-angiography
#32
JOURNAL ARTICLE
Feng Zhang, Ying'an Li, Zijing Du, Hong Sun, Lijie Xie, Yingying Liang, Siwen Zang, Wei Sun, Honghua Yu, Yijun Hu
INTRODUCTION: The study aimed to evaluate the effect of mydriasis on macular and peripapillary metrics with swept-source optical coherence tomography angiography (SS-OCTA) in healthy subjects. METHODS: Thirty-five healthy subjects were included. The macular region was scanned by the 3×3mm mode and 6×6mm mode, and the peripapillary region was scanned by the 4.5×4.5mm mode on both eyes with SS-OCTA before and after mydriasis. Macular and peripapillary metrics, including retinal vessel density (VD) and fundus thickness were measured by the built-in program...
2024: Frontiers in Endocrinology
https://read.qxmd.com/read/38479350/glycemic-control-and-retinal-microvascular-changes-in-type-2-diabetes-mellitus-patients-without-clinical-retinopathy
#33
JOURNAL ARTICLE
Kangmin Lee, Ga Hye Lee, Seung Eun Lee, Jee Myung Yang, Kunho Bae
BACKGROUND: To investigate the association of glycemic control and retinal microvascular changes in patients with type 2 diabetes mellitus (T2DM) without diabetic retinopathy (DR). METHODS: This retrospective, observational, cohort study included patients with T2DM without DR. The patients were categorized into intensive control (IC; mean glycosylated hemoglobin [HbA1c] ≤7.0%) and moderate control (MC; mean HbA1c >7.0%) groups. Optical coherence tomography (OCT) and swept-source OCT angiography (OCTA) image parameters were compared between three groups, including healthy controls...
March 13, 2024: Diabetes & Metabolism Journal
https://read.qxmd.com/read/38478099/axial-length-more-than-aging-decreases-the-thickness-and-superficial-vessel-density-of-retinal-nerve-fiber-layer-in-non-glaucomatous-eyes
#34
JOURNAL ARTICLE
Kuan-I Huang, Fang-Ying Su, Heng-Yen Ho, Heng-Chen Ho, Yan-Wu Chen, Chih-Kuo Lee, Feipei Lai, Henry Horng-Shing Lu, Mei-Lan Ko
PURPOSE: This study seeks to build a normative database for the vessel density of the superficial retina (SVD) and evaluate how changes and trends in the retinal microvasculature may be influenced by age and axial length (AL) in non-glaucomatous eyes, as measured with optical coherence tomography angiography (OCTA). METHODS: We included 500 eyes of 290 healthy subjects visiting a county hospital. Each participant underwent comprehensive ophthalmological examinations and OCTA to measure the SVD and thickness of the macular and peripapillary areas...
March 13, 2024: International Ophthalmology
https://read.qxmd.com/read/38472377/qualitative-and-quantitative-comparisons-of-type-1-macular-neovascularizations-between-pachychoroid-neovasculopathy-and-neovascular-age-related-macular-degeneration-using-optical-coherence-tomography-angiography
#35
JOURNAL ARTICLE
Özge Yanık, Sibel Demirel, Gökçen Özcan, Figen Batıoğlu, Emin Özmert
OBJECTIVES: To compare qualitative and quantitative features of type 1 macular neovascularizations (MNV) in pachychoroid neovasculopathy (PNV) and neovascular age-related macular degeneration (nAMD). METHODS: Forty-three treatment-naive eyes of 41 PNV patients and 40 treatment-naive eyes of 38 patients with nAMD were included. The patients were classified as PNV or nAMD according to the presence of pachychoroid features and soft/reticular drusen. Presence of central trunk and maturity of the MNV were evaluated on optical coherence tomography angiography (OCTA) images...
March 12, 2024: Eye
https://read.qxmd.com/read/38472220/towards-standardising-retinal-oct%C3%A2-angiography-image-analysis-with-open-source-toolbox-octava
#36
JOURNAL ARTICLE
Gavrielle R Untracht, Madeleine S Durkee, Mei Zhao, Andrew Kwok-Cheung Lam, Bartosz L Sikorski, Marinko V Sarunic, Peter E Andersen, David D Sampson, Fred K Chen, Danuta M Sampson
Quantitative assessment of retinal microvasculature in optical coherence tomography angiography (OCTA) images is important for studying, diagnosing, monitoring, and guiding the treatment of ocular and systemic diseases. However, the OCTA user community lacks universal and transparent image analysis tools that can be applied to images from a range of OCTA instruments and provide reliable and consistent microvascular metrics from diverse datasets. We present a retinal extension to the OCTA Vascular Analyser (OCTAVA) that addresses the challenges of providing robust, easy-to-use, and transparent analysis of retinal OCTA images...
March 12, 2024: Scientific Reports
https://read.qxmd.com/read/38471086/concentric-macular-rings-sign-in-combined-hamartoma-of-retina-and-retinal-pigment-epithelium
#37
JOURNAL ARTICLE
Lívia da Silva Conci, Renata Martins Maia, Rodrigo Pessoa Cavalcanti Lira, Leandro Cabral Zacharias, Eduardo Cunha de Souza, Sergio Luis Gianotti Pimentel, Carol Shields
PURPOSE: To describe two cases of concentric macular rings (CMR) sign in patients with combined hamartoma of retina and retinal pigment epithelium (CHRRPE). METHODS: History and clinical examination, spectral-domain optical coherence tomography (SD-OCT), and optic coherence tomography angiography (OCTA). RESULTS: The first patient was a 26-year-old woman with clinical diagnosis of Neurofibromatosis type 2. The Best-Corrected Visual Acuity (BCVA) was 20/25 in the right eye (OD) and 20/20 in the left eye (OS)...
March 1, 2024: Retinal Cases & Brief Reports
https://read.qxmd.com/read/38470651/vision-related-quality-of-life-in-patients-with-systemic-lupus-erythematosus
#38
JOURNAL ARTICLE
Francisco de Asís Bartol-Puyal, María Chacón González, Borja Arias-Peso, Damián García Navarro, Silvia Méndez-Martínez, María Pilar Ruiz Del Tiempo, Luis Sáez Comet, Luis Pablo Júlvez
PURPOSE: To assess vision-related quality of life (VRQoL) in patients with systemic lupus erythematosus (SLE) under treatment with hydroxychloroquine (HCQ), and to find the influencing factors. METHODS: Cross-sectional study enrolling SLE patients for less than ten years (Group 1), SLE patients for more than ten years (Group 2), and healthy controls (Group 3). SLE patients should be under treatment with HCQ but without ophthalmological affection. Schirmer test, best-corrected visual acuity (BCVA), axial length (AL) with optical biometry, and swept-source optical coherence tomography-angiography (OCTA) Triton (Topcon) were performed...
February 24, 2024: Healthcare (Basel, Switzerland)
https://read.qxmd.com/read/38467951/changes-in-retinal-vascular-density-measured-by-optical-coherence-tomography-angiography-in-patients-with-carotid-artery-stenosis-after-carotid-artery-stenting-and-angioplasty
#39
JOURNAL ARTICLE
Murat Karapapak, Serhat Ermis, Petek Aksöz Bolat, Mehmet Cingöz, Çağrı Erdim, Ece Özal, Sadık Altan Özal
PURPOSE: The aim of this study was to compare the effect of carotid artery stenting and angioplasty (CASA) on retinal vascular density (VD) in patients with severe carotid stenosis with a healthy control group and to evaluate using optical coherence tomography angiography (OCTA). METHODS: For this prospective study, eyes on the operated side constituted the ipsilateral eye group, and the other eye constituted the contralateral eye group. 40 eyes of 40 patients with ipsilateral eye of carotisid artery stenosis (CAS), 34 eyes on contralateral side, and 30 healthy eyes (control group) were included in this study...
March 11, 2024: International Ophthalmology
https://read.qxmd.com/read/38466290/genotype-phenotype-of-crb1-associated-early-onset-retinal-dystrophy-novel-insights-on-retinal-architecture-and-therapeutic-window-for-clinical-trials
#40
JOURNAL ARTICLE
Yili Jin, Songshan Li, Zhaoxin Jiang, Limei Sun, Li Huang, Ting Zhang, Xinyu Liu, Xiaoyan Ding
PURPOSE: The purpose of this study was to investigate the genotypic and phenotypic characteristics of CRB1-associated early onset retinal dystrophy (CRB1-eoRD) and retinal architecture by swept-source optical coherence tomography (SS-OCT). METHODS: Eleven probands with CRB1-eoRD were recruited. Clinical information, genetic analysis, and comprehensive ophthalmic examinations including SS-OCT and SS-OCT angiography (SS-OCTA) were conducted. RESULTS: A total of 81...
March 5, 2024: Investigative Ophthalmology & Visual Science
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