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https://www.readbyqxmd.com/read/28806613/automatic-blood-vessels-segmentation-based-on-different-retinal-maps-from-octa-scans
#1
Nabila Eladawi, Mohammed Elmogy, Omar Helmy, Ahmed Aboelfetouh, Alaa Riad, Harpal Sandhu, Shlomit Schaal, Ayman El-Baz
The retinal vascular network reflects the health of the retina, which is a useful diagnostic indicator of systemic vascular. Therefore, the segmentation of retinal blood vessels is a powerful method for diagnosing vascular diseases. This paper presents an automatic segmentation system for retinal blood vessels from Optical Coherence Tomography Angiography (OCTA) images. The system segments blood vessels from the superficial and deep retinal maps for normal and diabetic cases. Initially, we reduced the noise and improved the contrast of the OCTA images by using the Generalized Gauss-Markov random field (GGMRF) model...
August 7, 2017: Computers in Biology and Medicine
https://www.readbyqxmd.com/read/28804464/retinal-vascular-autoregulation-during-phase-iv-of-the-valsalva-maneuver-an-optical-coherence-tomography-angiography-study-in-healthy-chinese-adults
#2
Yuan Zong, Huan Xu, Jian Yu, Chunhui Jiang, Xiangmei Kong, Yi He, Xinghuai Sun
The impairment of retinal vascular autoregulation can be an early manifestation of many systemic and ocular diseases. Therefore, quantifying retinal vascular autoregulation in a non-invasive manner is very important. This study evaluated the effects of a Valsalva maneuver (VM)-induced blood pressure increases on retinal vascular autoregulation. Parafoveal and peripapillary retinal vessel density were measured with optical coherence tomography angiography before (baseline) and 5 s after each subject completed a VM (Phase IV [VM-IV])...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28803250/optical-coherence-tomography-angiography-in-children-with-leber-coats-disease
#3
Michele Fortunato, Angela Turtoro, Gilda Cennamo
INTRODUCTION: The aim of this work was to describe the optical coherence tomography (OCT) angiography (OCTA) features in paediatric Leber-Coats disease. METHODS: Three children presenting with unilateral, clinically active Leber-Coats disease were evaluated using spectral domain OCT and OCTA. OCT angiograms were analysed and compared with the current literature. RESULTS: All 3 OCT angiograms showed that the vessels had lost most of their collateral branches and presented many loops...
August 12, 2017: Ophthalmic Research
https://www.readbyqxmd.com/read/28799180/accuracy-of-octa-polar-bioelectrical-impedance-analysis-for-the-assessment-of-total-and-appendicular-body-composition-in-children-and-adolescents-with-hiv-comparison-with-dual-energy-x-ray-absorptiometry-and-air-displacement-plethysmography
#4
J A C de Castro, L R A de Lima, D A S Silva
BACKGROUND: Body composition analysis has been used to investigate fat mass (FM) and bone mineral content (BMC) in children and adolescents diagnosed with HIV. Investigating the validity of bioelectrical impedance analysis (BIA) is interesting with respect to testing useful techniques for monitoring body composition in children and adolescents in clinical practice. The present study aimed to determine the validity of body composition analysis by BIA compared to dual-energy X-ray absorptiometry (DXA) and air displacement plethysmography (ADP) in children and adolescents an HIV diagnosis...
August 10, 2017: Journal of Human Nutrition and Dietetics: the Official Journal of the British Dietetic Association
https://www.readbyqxmd.com/read/28797550/optical-coherence-tomography-angiography-of-the-peripapillary-retina-in-primary-angle-closure-glaucoma
#5
Shunhua Zhang, Chan Wu, Liang Liu, Yali Jia, Yao Zhang, Yang Zhang, Hua Zhang, Yong Zhong, David Huang
PURPOSE: To measure the change of peripapillary retinal vessel density (VD) in eyes with a history of acute primary angle closure glaucoma (PACG). DESIGN: Case-control study. METHODS: Twenty-one consecutive Chinese patients with history of unilateral acute PACG were enrolled. Eyes with acute PACG constituted the case group, while the contralateral eyes without attack constituted the control. All patients underwent ophthalmic examinations including best-corrected visual acuity, intraocular pressure, and visual field (VF)...
August 7, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28795246/bilateral-multiple-evanescent-white-dot-syndrome
#6
Chiara Veronese, Chiara Maiolo, Mariachiara Morara, Grayson W Armstrong, Antonio P Ciardella
PURPOSE: To present a single case of bilateral multiple evanescent white dot syndrome (MEWDS). METHODS: A single case with three months of follow-up using imaging studies including fundus color photography (FP), fluorescein angiography (FA), indocyanine green angiography (ICGA), fundus autofluorescence (FAF), spectral-domain optical coherence tomography (SD-OCT), en face SD-OCT and optical coherence tomography angiography (OCTA) is presented. RESULTS: The patient presented with bilateral MEWDS, ultimately with complete resolution of symptoms...
August 9, 2017: International Ophthalmology
https://www.readbyqxmd.com/read/28794076/swept-source-oct-angiography-imaging-of-the-macular-capillary-network-in-glaucoma
#7
Handan Akil, Vikas Chopra, Mayss Al-Sheikh, Khalil Ghasemi Falavarjani, Alex S Huang, SriniVas R Sadda, Brian A Francis
PURPOSE: To evaluate the macular capillary network density of superficial and deep retinal layers (SRL/DRL) by swept-source optical coherence tomography angiography (OCTA) in patients with primary open angle glaucoma (POAG) and to compare the results with those of normal subjects. METHOD: In this prospective study, 24 eyes of 24 normal individuals and 24 eyes of 24 patients with mild to moderate POAG underwent fovea centred 6×6 mm cube macular OCTA imaging by a swept-source OCTA device (Triton, Topcon, Tokyo, Japan)...
August 9, 2017: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/28791067/optical-coherence-tomography-angiography-a-new-tool-in-glaucoma-diagnostics-and-research
#8
Ramin Daneshvar, Kouros Nouri-Mahdavi
Optical coherence tomography angiography (OCTA) is a new modality in ocular imaging which provides high resolution view of the vascular structures in the retina and optic nerve head. This technology has the advantages of being noninvasive, rapid and reproducible. OCTA is becoming a valuable tool for evaluating many retinal and optic nerve diseases. This article provides a brief introduction to the technology and its application in the field of glaucoma diagnostics.
July 2017: Journal of Ophthalmic & Vision Research
https://www.readbyqxmd.com/read/28782513/the-effect-of-age-on-the-response-of-retinal-capillary-filling-to-changes-in-intraocular-pressure-measured-by-optical-coherence-tomography-angiography
#9
Xiaoyun Jiang, Elaine Johnson, William Cepurna, Diana Lozano, Shaojie Men, Ruikang K Wang, John Morrison
PURPOSE: To compare the effect of elevated intraocular pressure (IOP) on retinal capillary filling in elderly vs adult rats using optical coherence tomography angiography (OCTA). METHODS: The IOP of elderly (24-month-old, N=12) and adult (6-8month-old, N=10) Brown Norway rats was elevated in 10mmHg increments from 10 to 100mmHg. At each IOP level, 3D OCT data were captured using an optical microangiography (OMAG) scanning protocol and then post-processed to obtain both structural and vascular images...
August 3, 2017: Microvascular Research
https://www.readbyqxmd.com/read/28781889/evaluation-of-macular-and-peripapillary-vessel-flow-density-in-eyes-with-no-known-pathology-using-optical-coherence-tomography-angiography
#10
Muhammad Hassan, Mohammad Ali Sadiq, Muhammad Sohail Halim, Rubbia Afridi, Mohamed K Soliman, Salman Sarwar, Aniruddha Agarwal, Diana V Do, Quan Dong Nguyen, Yasir Jamal Sepah
PURPOSE: To assess normal vessel flow density (VFD) in macular and peripapillary regions of eyes with no known ocular pathology using optical coherence tomography angiography (OCTA). METHODS: AngioVue (Optovue, Fremont, CA, USA) was used to capture OCTA images. A 3 × 3 mm grid and a 4.5 × 4.5 mm grid was used to scan parafoveal and peripapillary regions, respectively. ReVue software was utilized to measure VFD in five sectors within the inner two circles of ETDRS grid in macular region and correlated to retinal thickness of same sectors...
2017: International Journal of Retina and Vitreous
https://www.readbyqxmd.com/read/28774527/optical-coherence-tomography-angiography-artifacts-in-retinal-pigment-epithelial-detachment
#11
Ricardo N Louzada, Talisa E de Carlo, Mehreen Adhi, Eduardo A Novais, Mary K Durbin, Emily Cole, Mark Lane, Omid Moghimi, Malvika Arya, Marco Bonini Filho, Andre J Witkin, Caroline R Baumal, Marcos Ávila, Jay S Duker, Nadia K Waheed
OBJECTIVE: To describe optical coherence tomography angiography (OCTA) reflectance artifacts secondary to retinal pigment epithelial detachment (RPED). DESIGN: Retrospective review. METHODS: Four eyes from 4 subjects were included. Three presented with RPED and 1 eye was a normal control. Two eyes diagnosed with RPED and the normal eye were evaluated using en face OCTA centred at the fovea acquired using the RTVue XR Avanti (Optovue Inc). In the third eye with RPED, OCTA imaging was performed using a CIRRUS 5000 prototype modified to do OCTA imaging on a spectral domain OCT platform provided by Carl Zeiss Meditec, Inc...
August 2017: Canadian Journal of Ophthalmology. Journal Canadien D'ophtalmologie
https://www.readbyqxmd.com/read/28767460/optic-nerve-head-drusen-imaging-using-optical-coherence-tomography-angiography
#12
Elsa Flores-Reyes, Kirsten Hoskens, Kaweh Mansouri
PURPOSE: To describe findings and utility of optical coherence tomography angiography (OCTA) in optic nerve head drusen (ONHD). OBSERVATIONS: A 57-year-old white man presented with a decrease in contrast sensitivity of the inferior visual field in both eyes. Clinical examination, visual fields, optical coherence tomography, fundus autofluorescence and OCTA revealed ONHD bilaterally. A focal decrease in vessel density within the localization of ONHD in both eyes was demonstrated suggesting a connection between those findings...
August 1, 2017: Journal of Glaucoma
https://www.readbyqxmd.com/read/28765145/optical-coherence-tomography-angiography-characterisation-of-best-disease-and-associated-choroidal-neovascularisation
#13
Abhilash Guduru, Arushi Gupta, Mudit Tyagi, Subhadra Jalali, Jay Chhablani
AIMS: To characterise the vasculature of the retina in patients with Best vitelliform dystrophy, including those with choroidal neovascularisation (CNV), using optical coherence tomography angiography (OCTA) and correlate with fluorescein angiography (FA). METHODS: This prospective observational study included 19 eyes of 10 patients with Best disease. Using OCTA, all layers of retina were qualitatively characterised for each eye. Patients with CNV also underwent FA, and areas of CNV were measured by OCTA and FA and correlated...
August 1, 2017: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/28763558/radiation-maculopathy-after-proton-beam-therapy-for-uveal-melanoma-optical-coherence-tomography-angiography-alterations-influencing-visual-acuity
#14
Alexandre Matet, Alejandra Daruich, Leonidas Zografos
Purpose: To analyze microvascular and structural changes in radiation maculopathy and their influence on visual acuity (VA), using optical coherence tomography (OCT) and OCT angiography (OCTA). Methods: This was a retrospective analysis of consecutive patients with radiation maculopathy, 12 months or more after proton-beam irradiation for uveal melanoma, imaged with fluorescein angiography, OCT, and OCTA. Clinical parameters potentially affecting VA were recorded, including OCTA-derived metrics: foveal avascular zone (FAZ) area, vascular density, and local fractal dimension of the superficial (SCP) and deep capillary plexuses (DCP)...
August 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/28761762/parafoveal-oct-angiography-features-in-diabetic-patients-without-clinical-diabetic-retinopathy-a-qualitative-and-quantitative-analysis
#15
Mathilde M Goudot, Anne Sikorav, Oudy Semoun, Alexandra Miere, Camille Jung, Blandine Courbebaisse, Mayer Srour, Joseph G Freiha, Eric H Souied
PURPOSE: To evaluate the capacity of OCT angiography (OCTA) for detecting infraclinical lesions in parafoveal capillaries in diabetic patients without diabetic retinopathy (DR). METHODS: This prospective observational cross-sectional case-control study analyzed the superficial and deep capillary plexuses (SCP and DCP) on macular OCTA scans (3 × 3 mm) centered on the fovea. We compared 22 diabetic patients (34 eyes included) without DR diagnosis on color fundus photographs, with 22 age- and gender-matched nondiabetic controls (40 eyes included)...
2017: Journal of Ophthalmology
https://www.readbyqxmd.com/read/28760677/optical-coherence-tomography-angiography-a-comprehensive-review-of-current-methods-and-clinical-applications
#16
REVIEW
Amir H Kashani, Chieh-Li Chen, Jin K Gahm, Fang Zheng, Grace M Richter, Philip J Rosenfeld, Yonggang Shi, Ruikang K Wang
OCT has revolutionized the practice of ophthalmology over the past 10-20 years. Advances in OCT technology have allowed for the creation of novel OCT-based methods. OCT-Angiography (OCTA) is one such method that has rapidly gained clinical acceptance since it was approved by the FDA in late 2016. OCTA images are based on the variable backscattering of light from the vascular and neurosensory tissue in the retina. Since the intensity and phase of backscattered light from retinal tissue varies based on the intrinsic movement of the tissue (e...
July 28, 2017: Progress in Retinal and Eye Research
https://www.readbyqxmd.com/read/28750113/handheld-optical-coherence-tomography-angiography-and-ultra-wide-field-optical-coherence-tomography-in-retinopathy-of-prematurity
#17
J Peter Campbell, Eric Nudleman, Jianlong Yang, Ou Tan, R V Paul Chan, Michael F Chiang, David Huang, Gangjun Liu
Importance: Retinopathy of prematurity (ROP) is a leading cause of childhood blindness worldwide. Optical coherence tomography (OCT) has improved the care of adults with vitreoretinal disease, and OCT angiography (OCTA) is demonstrating promise as a technique to visualize the retinal vasculature with lower risk and cost than fluorescein angiography. However, to date, there are no commercially available devices able to obtain ultra-wide-field OCT or OCTA images in neonates. Objective: To obtain ultra-wide-field OCT and OCTA images in neonates with ROP using a prototype handheld OCT and OCTA device...
July 27, 2017: JAMA Ophthalmology
https://www.readbyqxmd.com/read/28744658/characteristics-of-retinal-vessels-in-surgically-closed-macular-hole-an-optical-coherence-tomography-angiography-study
#18
Cheolmin Yun, Jaemoon Ahn, Mingue Kim, Jee Taek Kim, Soon-Young Hwang, Seong-Woo Kim, Jaeryung Oh
PURPOSE: The purpose of our study was to investigate characteristics of retinal vessels in eyes with surgically closed macular holes (MH). METHODS: We included patients who underwent surgery for idiopathic MH and a follow-up examination using optical coherence tomography angiography (OCTA). The area of the foveal avascular zone (FAZ) and retinal vascular densities of the superficial capillary plexus (SCP) and deep capillary plexus (DCP) were calculated on the postoperative OCTA images and compared with those of age-matched normal controls...
July 25, 2017: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/28744554/age-related-alterations-in-the-retinal-microvasculature-microcirculation-and-microstructure
#19
Yantao Wei, Hong Jiang, Yingying Shi, Dongyi Qu, Giovanni Gregori, Fang Zheng, Tatjana Rundek, Jianhua Wang
Purpose: To characterize age-related alterations in the retinal microcirculation, microvascular network, and microstructure in healthy subjects. Methods: Seventy-four healthy subjects aged from 18 to 82 years were recruited and divided into four age groups (G1 with age <35 years, G2 with age 35 ∼ 49 years, G3 with age 50 ∼ 64 years, and G4 with age ≥65 years). Custom ultra-high resolution optical coherence tomography (UHR-OCT) was used to acquire six intraretinal layers of the macula...
July 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/28739965/attempted-synthesis-of-ortho-phenylene-phosphino-tritylium-cations
#20
Kantapat Chansaenpak, Mengxi Yang, François P Gabbaï
With the synthesis of ortho-phenylene phosphino-tritylium cations as an objective, we generated (2-lithiophenyl)diphenylphosphine and (2-lithiophenyl)di-isopropylphosphine and allowed these organolithium reagents to react with benzophenone. The resulting phosphino-triarylcarbinols were allowed to react with HBF4 in the presence of trifluoroacetic anhydride in order to generate the corresponding cations. Instead of the targeted ortho-phenylene phosphino-tritylium, the cations formed in these reactions were identified as the four-membered phosphonium species 7,7-bis(phenyl)-8,8-bis(phenyl)-7-phosphoniabicyclo[4...
August 28, 2017: Philosophical Transactions. Series A, Mathematical, Physical, and Engineering Sciences
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