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Lung anatomy

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https://www.readbyqxmd.com/read/28903835/soyabean-oil-supplementation-effects-on-perivascular-inflammation-in-lungs-induced-by-bisphenol-a-a-histological-study
#1
Sadia Shaukat, Shabnam Hamid, Faiza Umbreen
OBJECTIVE: To determine the effect of soyabean oil supplementation on perivascular inflammation in lungs of adult mice induced by Bisphenol A(BPA). STUDY DESIGN: An experimental study. PLACE AND DURATION OF STUDY: Department of Anatomy, Army Medical College, Rawalpindi, in collaboration with the Animal House, National Institute of Health, Islamabad, from June to November 2016. METHODOLOGY: Thirty male and female BALB/c mice were divided into three groups, of 10 animals each...
August 2017: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
https://www.readbyqxmd.com/read/28901622/assessment-of-prior-image-induced-nonlocal-means-regularization-for-low-dose-ct-reconstruction-change-in-anatomy
#2
Hao Zhang, Jianhua Ma, Jing Wang, William Moore, Zhengrong Liang
PURPOSE: Repeated computed tomography (CT) scans are prescribed for some clinical applications such as lung nodule surveillance. Several studies have demonstrated that incorporating a high-quality prior image into the reconstruction of subsequent low-dose CT (LDCT) acquisitions can either improve image quality or reduce data fidelity requirements. Our proposed previous normal-dose image induced nonlocal means (ndiNLM) regularization method for LDCT is an example of such a method. However, one major concern with prior image based methods is that they might produce false information when the prior image and the current LDCT image show different structures (for example, if a lung nodule emerges, grows, shrinks, or disappears over time)...
September 2017: Medical Physics
https://www.readbyqxmd.com/read/28900048/community-acquired-pneumonia
#3
Jennifer Franco
The most commonly ordered radiologic examination is the chest radiograph, and it is considered the gold standard for diagnosing pneumonia. For this reason, it is essential that radiologic technologists understand the disease and how it affects patients. This article discusses the anatomy of the lungs, along with the epidemiology, pathophysiology, risk factors, signs and symptoms, diagnosis, treatment, and complications of community-acquired pneumonia.
July 2017: Radiologic Technology
https://www.readbyqxmd.com/read/28898423/iterative-volume-of-interest-based-4d-cone-beam-ct
#4
Rachael Martin, Moiz Ahmad, Geoffrey Hugo, Tinsu Pan
PURPOSE: 4D cone-beam CT (CBCT) has potential applications in soft tissue alignment and tumor motion verification at the time of radiation treatment. However, prominent streak artifacts with conventional image reconstructions have limited its clinical use and alternative reconstructions are generally too computationally expensive for the time available. We propose an iterative volume of interest based (I4D VOI) reconstruction technique, where 4D reconstruction is only performed within a VOI, to limit streak artifacts with limited added computation time...
September 12, 2017: Medical Physics
https://www.readbyqxmd.com/read/28895301/early-leaflet-thrombosis-complicating-transcatheter-implantation-of-a-sapien-3-valve-in-a-native-right-ventricular-outflow-tract
#5
Mounir Riahi, Philipp Blanke, John Webb, Ronald G Carere
A 59-year-old female with Tetralogy of Fallot had a previous complete repair with RVOT patch enlargement. She developed subsequent severe symptomatic (NYHA III) pulmonary regurgitation with severe RV dilatation. She had a concomitant interstitial lung disease secondary to hypersensitivity pneumonitis that precluded her from cardiac surgery. After preprocedural assessment using computed tomography, echocardiography and invasive angiography we decided to implant a 29 mm Edwards Sapien 3 valve without pre-stenting...
September 12, 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/28882284/harmony-feasibility-trial-acute-and-short-term-outcomes-with-a-self-expanding-transcatheter-pulmonary-valve
#6
Lisa Bergersen, Lee N Benson, Matthew J Gillespie, Sharon L Cheatham, Andrew M Crean, Kan N Hor, Eric M Horlick, Te-Hsin Lung, Brian T McHenry, Mark D Osten, Andrew J Powell, John P Cheatham
OBJECTIVES: This study sought to obtain in vivo data to confirm assumptions on device loading conditions and assess procedural feasibility, safety, and valve performance. BACKGROUND: The Harmony transcatheter pulmonary valve (Medtronic, Minneapolis, Minnesota) was designed for patients with severe pulmonary regurgitation who require pulmonary valve replacement. METHODS: Three sites participated in this first Food and Drug Administration-approved early feasibility study using an innovative device design to accommodate the complex anatomy of the right ventricular outflow tract...
September 11, 2017: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/28871981/inversed-planned-respiratory-phase-gating-in%C3%A2-lung-conformal-radiation-therapy
#7
Arezoo Modiri, Pouya Sabouri, Xuejun Gu, Robert Timmerman, Amit Sawant
PURPOSE: To assess whether the optimal gating window for each beam during lung radiation therapy with respiratory gating will be dependent on a variety of patient-specific factors, such as tumor size and location and the extent of relative tumor and organ motion. METHODS AND MATERIALS: To create optimal gating treatment plans, we started from an optimized clinical plan, created a plan per respiratory phase using the same beam arrangements, and used an inverse planning optimization approach to determine the optimal gating window for each beam and optimal beam weights (ie, monitor units)...
October 1, 2017: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/28862385/tailoring-stents-to-fit-the-anatomy-of-unique-vascular-stenoses-in-congenital-heart-disease
#8
Patrick M Sullivan, Aimee Liou, Cheryl Takao, Henri Justino, Christopher J Petit, Jorge D Salazar, Frank F Ing
BACKGROUND: Unique and small anatomical features often preclude the use of available vascular stents in pediatric patients with congenital heart disease (CHD). OBJECTIVES: To report our experience and outcomes tailoring stents to fit unique anatomy, particularly in small children and infants with CHD. METHODS: Stent tailoring techniques included trimming, folding, and flaring. Patients receiving a tailored stent November 2002 to February 2015 were included in a retrospective analysis...
September 1, 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/28856408/three-dimensional-ct-angiography-of-anatomic-variations-in-the-pulmonary-arterial-tree
#9
Alex Fourdrain, Florence De Dominicis, Chloé Blanchard, Jules Iquille, Sophie Lafitte, Pierre-Louis Beuvry, David Michel, Geoni Merlusca, Eric Havet, Pascal Berna
PURPOSE: Anatomic variations of the pulmonary arterial tree can cause technical difficulties during pulmonary lobectomy in general and video-assisted thoracic surgery (VATS). Using CT angiography and 3D reconstruction, we sought to identify anatomic variations of the pulmonary arterial tree and assess their respective frequencies. METHODS: We retrospectively studied 88 pulmonary arterial trees in 44 patients having undergone VATS lobectomy for lung cancer over an 18-month period in Amiens University Hospital's Department of Thoracic Surgery...
August 30, 2017: Surgical and Radiologic Anatomy: SRA
https://www.readbyqxmd.com/read/28855323/rib-kinematics-during-lung-ventilation-in-the-american-alligator-alligator-mississippiensis-an-xromm-analysis
#10
Robert J Brocklehurst, Sabine Moritz, Jonathan Codd, William I Sellers, Elizabeth L Brainerd
The current hypothesis regarding the mechanics of breathing in crocodylians is that the double-headed ribs, with both a capitulum and tuberculum, rotate about a constrained axis passing through the two articulations; moreover, this axis shifts in the caudal thoracic ribs, as the vertebral parapophysis moves from the centrum to the transverse process. Additionally, the ventral ribcage in crocodylians is thought to possess additional degrees of freedom through mobile intermediate ribs. In this study, X-ray reconstruction of moving morphology (XROMM) was used to quantify rib rotation during breathing in American alligators...
September 1, 2017: Journal of Experimental Biology
https://www.readbyqxmd.com/read/28852474/the-prevalence-of-pulmonary-complications-after-thoracic-and-abdominal-surgery-and-associated-risk-factors-in-patients-admitted-at-a-government-hospital-in-harare-zimbabwe-a-retrospective-study
#11
Cathrine Tadyanemhandu, Rufaro Mukombachoto, Clement Nhunzvi, Farayi Kaseke, Vasco Chikwasha, Samson Chengetanai, Shamila Manie
BACKGROUND: The burden of HIV/AIDS in Sub-Saharan Africa has presented unusual and challenging acute surgical problems across all specialties. Thoraco-abdominal surgery cuts through muscle and thereby disrupts the normal anatomy and activity of the respiratory muscles leading to reduced lung volumes and putting the patients at greater risk of developing post-operative pulmonary complications (PPCs). PPCs remain an important cause of post-operative morbidity, mortality, and impacts on the long-term outcomes of patients post hospital discharge...
2017: Perioperative Medicine
https://www.readbyqxmd.com/read/28790285/-postoperative-chylotholax-intraoperative-prevention-and-postoperative-management
#12
Tomohito Saito, Shuji Kariya, Tomohiro Murakawa
Postoperative chylothorax is a relatively rare but potentially fatal complication caused by iatrogenic injury to thoracic duct system, with an incidence ranging from 2 to 4% after major lung surgery or esophagectomy. The pathophysiologic features of chylothorax include dehydration, loss of nutrients and immunological components. Intraopreative prevention is the first step for the management, and treatment options include conservative therapy, percutaneous intervention, and redo-operation. Although the treatment algorithm has not been standardized, chylothorax which is refractory to conservative treatment, or that with high output greater than 1,000 ml/day should be treated aggressively with thoracic duct embolization or redo-operation in a timely fashion...
July 2017: Kyobu Geka. the Japanese Journal of Thoracic Surgery
https://www.readbyqxmd.com/read/28777699/multidetector-ct-for-evaluation-of-the-extrapleural-space
#13
Mario G Santamarina, Ignacio Beddings, Guillermo V Lermanda Holmgren, Hector Opazo Sanchez, Mariano M Volpacchio
The extrapleural space (EPS) is an anatomic space at the periphery of the chest that can be involved in a number of disease processes. This space lies between the inner surface of the ribs and the parietal pleura and contains adipose tissue, loose connective tissue, lymph nodes, vessels, endothoracic fascia, and the innermost intercostal muscle. It is often overlooked on cross-sectional imaging studies and almost invariably overlooked on conventional radiographic studies. At conventional radiography, the EPS occasionally can be seen when there is extrapleural fat proliferation, which might be confused with pleural thickening or pleural effusion...
September 2017: Radiographics: a Review Publication of the Radiological Society of North America, Inc
https://www.readbyqxmd.com/read/28760089/feasibility-of-proton-pencil-beam-scanning-treatment-of-free-breathing-lung-cancer-patients
#14
Annika Jakobi, Rosalind Perrin, Antje Knopf, Christian Richter
BACKGROUND: The interplay effect might degrade the dose of pencil beam scanning proton therapy to a degree that free-breathing treatment might be impossible without further motion mitigation techniques, which complicate and prolong the treatment. We assessed whether treatment of free-breathing patients without motion mitigation is feasible. MATERIAL AND METHODS: For 40 lung cancer patients, 4DCT datasets and individual breathing patterns were used to simulate 4D dynamic dose distributions of 3D treatment plans over 33 fractions delivered with an IBA universal nozzle...
August 1, 2017: Acta Oncologica
https://www.readbyqxmd.com/read/28751430/persistent-air-leak-after-pulmonary-transplantation
#15
Laurence Pearmain, Piotr Krysiak, John Blaikley, Mohamed Alaloul
A 59-year-old man with bilateral apical emphysema underwent a double lung transplant for end-stagechronic obstructive pulmonary disease leaving remnant right apical native tissue due to pleural adhesions. Initial postoperative course was uneventful until the chest drains were removed. This revealed a small pneumomediastinum, which progressively increased in size causing gross surgical emphysema. Re-insertion of the chest drain stabilised the patient so that the cause could be identified and corrected. Two bronchoscopies excluded anastomotic dehiscence as a cause...
July 27, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28740912/effect-of-variations-in-atelectasis-on-tumor-displacement-during-radiation-therapy-for-locally-advanced-lung-cancer
#16
Nathan Tennyson, Elisabeth Weiss, William Sleeman, Mihaela Rosu, Nuzhat Jan, Geoffrey D Hugo
PURPOSE: Atelectasis (AT), or collapsed lung, is frequently associated with central lung tumors. We investigated the variation of atelectasis volumes during radiation therapy and analyzed the effect of AT volume changes on the reproducibility of the primary tumor (PT) position. METHODS AND MATERIALS: Twelve patients with lung cancer who had AT and 10 patients without AT underwent repeated 4-dimensional fan beam computed tomography (CT) scans during radiation therapy per protocols that were approved by the institutional review board...
January 2017: Advances in Radiation Oncology
https://www.readbyqxmd.com/read/28740680/uniportal-video-assisted-thoracoscopic-right-upper-lobectomy-and-systemic-mediastinal-lymph-nodes-dissection
#17
Jia He, Dongjie Ma, Shanqing Li
Along with the progresses that have been made in techniques and instruments, uniportal video-assisted thoracoscopic surgery (VATS) became more and more popular. Here, we present the operation video of a 52-year-old female with early stage lung cancer in the right upper lobe (RUL), who underwent uniportal VATS right upper lobectomy and systemic mediastinal lymph nodes dissection performed by our team. The video demonstrated the Uniportal VATS techniques of hilar anatomy, bronchus and blood vessel separation, mediastinal lymph node areas exploration and en-bloc dissection...
June 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28734644/postmastectomy-radiation-therapy-technique-and-cardiopulmonary-sparing-a-dosimetric-comparative-analysis-between-photons-and-protons-with-free-breathing-versus-deep-inspiration-breath-hold
#18
Sagar A Patel, Hsiao-Ming Lu, Jacqueline A Nyamwanda, Rachel B Jimenez, Alphonse G Taghian, Shannon M MacDonald, Nicolas Depauw
PURPOSE: Dosimetric studies have suggested greater cardiopulmonary sparing with protons over photons for left-sided postmastectomy radiation therapy (PMRT). Modern techniques such as deep inspiration breath hold (DIBH) can help spare the heart. This analysis compares photon and proton delivery with and without DIBH. METHODS AND MATERIALS: Ten women with left breast cancer referred for PMRT on a prospective clinical trial with unfavorable cardiac anatomy underwent free breathing (FB) and DIBH computed tomography simulation...
June 21, 2017: Practical Radiation Oncology
https://www.readbyqxmd.com/read/28730763/dna-mismatch-repair-deficiency-in-lung-and-oral-cavity-carcinomas-the-role-of-histogenetic-origin
#19
Konstantina N Spetsotaki, Evangelos Tsiambas, Athanasios Stamatelopoulos, Panagiotis P Fotiades, Ioannis Kastanioudakis, Pericles Tomos, Vasileios Ragos
DNA mismatch repair system (DNA MMR) is a crucial genetic mechanism for DNA homeostasis in prokaryotic and eukaryotic cells. During DNA replication and also recombination, point intra-nucleotide errors including base deletion, insertion, and mis-incorporation happen. These raised abnormalities in the newly synthesized DNA strand could affect negatively the stability of the molecule and the function of the corresponding genes. DNA MMR proteins prevent these errors by recognizing and repairing them, securing directly the normal anatomy of the DNA double strand and indirectly the expression of the genes...
May 2017: Journal of B.U.ON.: Official Journal of the Balkan Union of Oncology
https://www.readbyqxmd.com/read/28669706/sinoatrial-node-toxicity-after-stereotactic-ablative-radiation-therapy-to-lung-tumors
#20
Yushen Qian, Han Zhu, Erqi L Pollom, Ben Y Durkee, Aadel A Chaudhuri, Michael F Gensheimer, Maximilian Diehn, David B Shultz, Billy W Loo
PURPOSE: Stereotactic ablative radiation therapy (SABR) is an established treatment for selected lung tumors. Sinoatrial node (SAN) toxicity after thoracic SABR has not been reported in the literature. We sought to understand the risk of SAN toxicity owing to incidental dose to the SAN from SABR. METHODS AND MATERIALS: We conducted a retrospective review of patients with early-stage lung cancer or limited pulmonary metastases who underwent thoracic SABR to a right-sided central lung tumor (within 2 cm of the mainstem bronchus or other mediastinal structures) between January 2008 and December 2014, analyzed a subset whose treatment imparted dose to the SAN exceeding 10% of the prescription dose, and examined patient and treatment dosimetric characteristics...
April 13, 2017: Practical Radiation Oncology
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