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Massive weight loss

Jonathan A Dunne, Justin C R Wormald, Reshma Ghedia, Mark Soldin
INTRODUCTION: National guidelines for commissioning of body contouring surgery (BCS) following massive weight loss (MWL) in England were published in 2014. Nearly three-quarters of patients who have MWL seek BCS; however, access is known to vary according to the region. The aim of national guidelines was to standardise access. The purpose of this study was to determine implementation of the national guidelines by clinical commissioning groups (CCGs) in England. MATERIALS AND METHODS: A cross-sectional, web-based survey was sent to all CCG chairs in England...
September 21, 2016: Journal of Plastic, Reconstructive & Aesthetic Surgery: JPRAS
Kathy A Schall, Kathleen A Holoyda, Mubina Isani, Ching-Ling Lien, Denise Al Alam, Tracy C Grikscheit
BACKGROUND: Signaling by fibroblast growth factor is critical for epithelial proliferation, differentiation, and the development of many organs, including the intestine. Fibroblast growth factor 10 and fibroblast growth factor 2c are upregulated after massive bowel resection during intestinal adaptation. This pathway is conserved highly. We hypothesized that inhibition of fibroblast growth factor signaling would impair intestinal adaptation in the zebrafish model of short bowel syndrome and allow insight into the negative regulation of this pathway...
October 19, 2016: Surgery
Yasuhiko Hayashi, Masahiro Oishi, Issei Fukui, Yasuo Sasagawa, Yasuhiro Aida, Mitsutoshi Nakada
BACKGROUND: In Rathke cleft cysts (RCCs), inflammation by the cyst contents infrequently spreads to the surrounding structures. Calcification, which is regarded as a consequence of chronic inflammation of the cyst wall, can rarely be found in RCCs, and moreover, ossification is extremely rare. CLINICAL PRESENTATION: A 60-year-old woman presented with headaches, fatigue and weight loss due to panhypopituitarism. Magnetic Resonance imaging revealed a mass lesion in the sellar region, which was comprised of two different parts, with hypointensity anteriorly and hyperintensity posteriorly on T1-weighted image (WI), and the rim with significant hypointensity entirely on T2-WI...
October 18, 2016: World Neurosurgery
Ingrid G M Poodt, Martine M van Dijk, Steven Klein, Maarten M Hoogbergen
: There is an exponential rise of patients with massive weight loss because of bariatric surgery or lifestyle changes. The result is an increase of patients with folds of redundant skin that may cause physical and psychological problems. The lower body lift is a procedure to correct deformities in the abdomen, mons, flanks, lateral thighs, and buttocks. Complication rates are quite high and could negatively affect the positive outcomes. The purpose of this study is to assess complication rates and to identify predictors of complications to optimize outcomes for patients after lower body lift surgery...
September 2016: Plastic and Reconstructive Surgery. Global Open
Manfred Schmidt, Dominik Duscher, Georg M Huemer
No abstract text is available yet for this article.
October 10, 2016: Plastic and Reconstructive Surgery
Nicolas Bertheuil, Antoine De Runz, Audrey Varin, Raphael Carloni, Caroline Francois, Benoit Chaput
No abstract text is available yet for this article.
October 10, 2016: Plastic and Reconstructive Surgery
Paul Girard, Benoit Chaput, Raphael Carloni, Eric Watier, Antoine De Runz, Nicolas Bertheuil
No abstract text is available yet for this article.
October 6, 2016: Plastic and Reconstructive Surgery
Alan Matarasso
No abstract text is available yet for this article.
October 6, 2016: Plastic and Reconstructive Surgery
Nicolas D Knuth, Darcy L Johannsen, Robyn A Tamboli, Pamela A Marks-Shulman, Robert Huizenga, Kong Y Chen, Naji N Abumrad, Eric Ravussin, Kevin D Hall
No abstract text is available yet for this article.
October 2016: Obesity
Itay Wiser, Eliezer Avinoah, Oren Ziv, Adam J Parnass, Roni Averbuch Sagie, Lior Heller, Tali Friedman
BACKGROUND: Laparoscopic adjustable gastric banding (LAGB) surgery is the safest yet least effective method for massive weight loss. Thirty to 50 percent of patients undergoing LAGB will regain part of their lost weight. OBJECTIVE: To evaluate the effect of body contouring plastic surgery (BCPS) following LAGB on long-term body mass index (BMI) control. SETTING: Department of Surgery A, Soroka University Medical Center, Beer-Sheva, Israel...
September 7, 2016: Journal of Plastic, Reconstructive & Aesthetic Surgery: JPRAS
Devina Willard, Jagriti Upadhyay, Chan Kim, Devin Steenkamp
CONTEXT: Type B insulin resistance syndrome is a rare disease which occurs due to the development of autoantibodies to the insulin receptor and can result in either severe insulin resistance and hyperglycemia or conversely hypoglycemia. Diabetes mellitus is often severe, usually transient and poorly responsive to exogenous insulin. Diabetic ketoacidosis is an unusual consequence of this most severe form of transient diabetes mellitus. CASE DESCRIPTION: A 39 year old Nigerian woman presented with significant weight loss, severe diabetic ketoacidosis and severe insulin resistance requiring massive doses of exogenous insulin...
September 16, 2016: Journal of Clinical Endocrinology and Metabolism
Ronan Thibault, Claude Pichard
PURPOSE OF REVIEW: In the context of the worldwide obesity epidemic, bariatric surgery is the only therapy associated with a sustainable weight loss and to midterm prevention of obesity-related complications. However, nutritional and behavioral multidisciplinary medical preparation, as well as long-term postoperative nutritional follow-up, is strongly advised to avoid postoperative surgical, nutritional, or psychiatric complications. RECENT FINDINGS: Due to a long history of restrictive diets and large body weight fluctuations, preoperative nutritional assessment and correction of vitamin and trace elements deficiencies are mandatory...
November 2016: Current Opinion in Clinical Nutrition and Metabolic Care
O Lotter, S Hoefert, M Micheel, P Gonser, H-E Schaller, J Rothenberger
BACKGROUND: Diagnosis Related Groups (DRG) were introduced in Germany as a medico-economic classification system in 2004. In this analysis, we looked at restorative surgery after massive weight loss, focusing on reimbursement of this fee-per-case system in comparison to costs to deduce possible effects on health care over time. MATERIAL AND METHODS: First we analysed the algorithms for the relevant DRGs including data about length of stay and reimbursement. Furthermore, we integrated cost data from German reference hospitals of the last 5 years as well as single-centre data from a university hospital...
August 2016: Handchirurgie, Mikrochirurgie, Plastische Chirurgie
Vilma Takayasu, Lorena Silva Laborda, Raquel Bernardelli, Henrique Trombini Pinesi, Marilia Polo Minguete E Silva, Viviane Chiavelli, Angélica Braz Simões, Aloisio Felipe-Silva
Amyloidosis comprises a group of diseases that occurs in five to nine cases per million patients per year worldwide irrespective of its classification. Although the hepatic involvement in primary amyloidosis is frequent, the clinical manifestations of liver amyloidosis are mild or even absent. The authors report the case of an aged man who complained of diffuse abdominal pain and marked weight loss and presented clinical signs of hepatopathy. Clinical workup revealed portal hypertension with ascites, hemorrhoids, and esophageal varices...
April 2016: Autopsy & case reports
Ritesh Prajapati, Ashish Kumar, Praveen Sharma, Vikas Singla, Naresh Bansal, Shashi Dhawan, Anil Arora
Leishmaniasis or kala-azar is a protozoan disease that can present as cutaneous, mucocutaneous, visceral, and disseminated disease. In India, it is usually localized in distinct areas of Bihar, Jharkhand, West Bengal, and parts of Eastern Uttar Pradesh. Visceral leishmaniasis (VL) involves the visceral organs, mainly the liver, the spleen and bone marrow. VL is characterized by prolonged fever, massive splenomegaly, weight loss, progressive anemia, pancytopenia, and hypergammaglobulinemia, and can be complicated by serious infections...
June 2016: Journal of Clinical and Experimental Hepatology
J Hacquard, M Haiun, T Bayti, N Ferry, J-B Andréoletti
INTRODUCTION: Massive weight loss leads to important cutaneous deformities with physical and psychological repercussions for patients. Lower bodylift is a procedure, which can restore the body contour. The aim of this study is to evaluate satisfaction and quality of life in patients who underwent lower bodylift and to review the complications of these procedures. MEANS AND METHODS: This is a retrospective study of 76 patients who underwent lower bodylift between 2012 and 2016...
July 26, 2016: Annales de Chirurgie Plastique et Esthétique
Dennis J Hurwitz, Omodele Ayeni
Plastic surgeons subspecializing in body contouring are meeting the challenge of postbariatric surgery massive weight loss patients. With an appreciation of the magnitude of the surface deformity, and altered metabolism, nutrition, and psychological makeup of these patients, innovative plastic surgeons have forged an organized approach to preparation, operative technique, and postoperative care. Patients at greatest risk for complications are identified, appraised, and either their condition improved or they are counselled to reduce expectations...
August 2016: Surgical Clinics of North America
Jing Jing Wang, Guang Liu, Yan-Bo Huang, Qiao-Hui Zeng, Guo-Sheng Song, Yi Hou, Lin Li, Song-Qing Hu
Effects of N-terminal domain of high molecular weight glutenin subunit (HMW-GS) 1Dx5 (1Dx5-N) on functional and structural properties of wheat dough were determined by farinographic and rheological analysis, size exclusion chromatography, non-reducing/reducing SDS-PAGE, total free sulfhydryl determination, scanning electron microscopy and Fourier transform infrared spectroscopy. Results showed that 1Dx5-N improved the quality of dough with the increased water absorption, dough stability time, elastic and viscous modulus, and the decreased degree of softening, loss tangent...
December 15, 2016: Food Chemistry
Zhitao Yu, Xueyao Zhang, Yiwen Wang, Bernard Moussian, Kun Yan Zhu, Sheng Li, Enbo Ma, Jianzhen Zhang
Cytochrome P450 superfamily proteins play important roles in detoxification of xenobiotics and during physiological and developmental processes. To contribute to our understanding of this large gene family in insects, we have investigated the function of the cytochrome P450 gene LmCYP4G102 in the migratory locust Locusta migratoria. Suppression of LmCYP4G102 expression by RNA interference (RNAi) does not interfere with moulting but causes rapid loss of body weight - probably due to massive loss of water, and death soon after moulting...
2016: Scientific Reports
Samer W Cabbabe
Bariatric surgery rates have increased in the United States concurrent with the rise in obesity. As a result of the massive weight loss from these surgeries, patients are left with a different set of functional and cosmetic issues related to excess skin. Plastic surgery has evolved to treat these unique issues faced by this patient population and has demonstrated beneficial effects. This article will provide an overview of the options available to massive weight loss patients to treat specifically affected area of the body...
May 2016: Missouri Medicine
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