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https://www.readbyqxmd.com/read/29319578/safety-and-utility-of-the-drainless-abdominoplasty-in-the-post-bariatric-surgery-patient
#1
Sidhbh Gallagher, Tahereh Soleimani, Christine Wang, Sunil Tholpady, Christopher Jones, William Sando
INTRODUCTION: Surgical drains are used in abdominoplasty patients to combat wound closure disruption by hematoma or seroma formation. Several recent publications have described techniques that allow abdominoplasty to be performed safely without the need for surgical drains. This has not, however, been described in the case of the bariatric patient, who is often considered to be of higher postoperative complication risk. Here, we describe our experience of the drainless abdominoplasty in patients who have undergone massive weight loss (MWL) after a bariatric procedure...
February 2018: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/29317315/carry-over-effects-modulated-by-salinity-during-the-early-ontogeny-of-the-euryhaline-crab-hemigrapsus-crenulatus-from-the-southeastern-pacific-coast-development-time-and-carbon-and-energy-content-of-offspring
#2
Ángel Urzúa, Miguel Bascur, Fabián Guzmán, Mauricio Urbina
Hemigrapsus crenulatus is a key species of coastal and estuarine ecosystems in the Southeastern Pacific and New Zealand. Since the gravid females-and their embryos-develop under conditions of variable salinity, we propose that low external salinity will be met with an increase in energy expenditures in order to maintain osmoregulation; subsequently, the use of energy reserves for reproduction will be affected. In this study, we investigate in H. crenulatus whether 1) the biomass and energy content of embryos is influenced by salinity experienced during oogenesis and embryogenesis and 2) how variation in the biomass and energy content of embryos affects larval energetic condition at hatching...
January 6, 2018: Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology
https://www.readbyqxmd.com/read/29310397/massive-rare-desmoplastic-fibroma-of-the-ilium-and-ischium-in-a-young-adult-a-case-report
#3
Xin-Nan Ma, Shuai Qiang, Tian-Yi Liu, Mei-Yu Cao, Song-Cen Lv
RATIONALE: Desmoplastic fibroma (DF) is a rare, locally invasive but benign bone tumor. It represents one of the rarest bone diseases, with an incidence of only 0.11% of all primary bone tumors. PATIENT CONCERNS: Herein, a case of massive and unusual DF, with simultaneous involvement of ilium and ischium, is described. A 29-year-old man suffered minor pain in his right hip for 2 years. It worsened after sudden movements, which prevented him from walking normally...
December 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29302559/peripheral-t-cell-lymphoma-not-otherwise-specified
#4
Kunal Kishor Jha, Suresh K Gupta, Harpreet Saluja, Nuwadatta Subedi
The peripheral T-cell lymphoma, not otherwise specified (PTCL, NOS) belongs to a heterogeneous class of aggressive neoplasms. Although several morphologic subtypes of this tumor have been described, no particular genetic, immunological, or distinct clinical features define this disease. Patients can experience night sweats, fever, lymphadenopathy, weight loss, splenomegaly, and/or skin changes. Common laboratory tests reveal that patients have anemia, thrombocytosis, lymphocytosis, eosinophilia, hypergammaglobulinemia, or increased lactate dehydrogenase...
April 2017: Journal of Family Medicine and Primary Care
https://www.readbyqxmd.com/read/29298971/an-autopsy-case-of-mesenteric-panniculitis-with-massive-pleural-effusions
#5
Hiroshi Kobayashi, Kenji Notohara, Tadashi Otsuka, Yuka Kobayashi, Masuo Ujita, Yuuki Yoshioka, Naomasa Suzuki, Ryuji Aoyagi, Riuko Ohashi, Toshimitsu Suzuki
BACKGROUND Mesenteric panniculitis (MP) is an idiopathic chronic inflammatory condition of the mesentery. The main symptoms include abdominal pain, abdominal distention, weight loss, fever, nausea, and vomiting. The patients also present with chylous ascites in 14% of the cases and chylous pleural effusion (CPE) in very rare occasions. Despite the previous view of excellent prognosis of MP, two recent papers reported several fatal cases. However, there are still only a few autopsy case reports that describe the macroscopic and histological details of MP cases...
January 4, 2018: American Journal of Case Reports
https://www.readbyqxmd.com/read/29285688/pancreatoblastoma-an-unusual-diagnosis-in-an-adult-patient
#6
Gonçalo Nunes, Hélder Coelho, Marta Patita, Rita Barosa, Pedro Pinto Marques, Lídia Roque Ramos, Maria José Brito, Aurora Tomaz, Jorge Fonseca
The authors describe a 31-year-old man admitted due to progressive weight loss, diarrhea and massive hepatomegaly. Laboratory data showed anemia (haemoglobin 11.7 g/dl), abnormal liver tests (total bilirubin 1.4 g/dl, aspartate aminotransferase 70 U/l, alanine aminotransferase 37 U/l and alkaline phosphatase 520 U/l). Abdominal ultrasound (US) displayed a large heterogeneous liver with a segment IV 25 mm nodule. Magnetic resonance revealed a 4 cm pancreatic tail mass and several liver nodules consistent with metastasis...
December 28, 2017: Clinical Journal of Gastroenterology
https://www.readbyqxmd.com/read/29228316/identification-of-a-critical-window-for-ganciclovir-induced-disruption-of-testicular-development-in-rats
#7
Katlyn Barp Meyer, Anderson Joel Martino Andrade, Amanda Caroline Venturelli, Diogo Henrique Kita, Dária Louise Barbosa Machado, Rafaela Adams Philipsen, Alluanan Adelson do Nascimento Silva, Isabelle Cantão, Davyson Moreira, Valdemiro Amaro da Silva Junior, Taiza Stumpp, Rosana Nogueira Morais
Ganciclovir (GCV) has been implicated in the development of testicular alterations. Exposure on gestational day (GD) 10 in rats induced permanent effects, including focal reduction or absence of germ cells (Sertoli cell-only tubules). Because the timing of exposure can be critical for testicular effects, we exposed rat dams to 300 mg/kg GCV (three 100mg/kg subcutaneous injections) on GD10, 14 and 19, when germ cells have high rates of migration, proliferation and are mitotically quiescent, respectively. Males exposed to GCV in utero on GD10 and 14 were evaluated for androgenization markers, serum and fecal androgens, and testicular histomorphometry at adulthood...
December 7, 2017: Toxicological Sciences: An Official Journal of the Society of Toxicology
https://www.readbyqxmd.com/read/29214335/commentary-mastopexy-on-reconstructed-breast-following-massive-weight-loss-an-innovative-technique-using-dermo-capsular-flaps
#8
Omar E Beidas, J Peter Rubin
No abstract text is available yet for this article.
December 6, 2017: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/29214086/erdheim-chester-disease-with-no-skeletal-bone-involvement-and-massive-weight-loss
#9
Hind Salama, Suleiman Kojan, Shaima Abdulrahman, Fahad Azzumeea, Ayman Alhejazi
Erdheim-Chester disease (ECD) is a rare type of non-Langerhans cell histiocytosis, with only 550 cases reported worldwide. ECD is characterized by diffuse histiocytic infiltration of multiorgans. The age of presentation of this disease is typically between 40 and 70 years. Bone disease is the most common symptom, as unique radiological findings of long bone sclerosis occur in 96% of cases. Furthermore, BRAF V600E mutation is detected in 60% of ECD cases. In this manuscript, we are describing a unique case of ECD; the patient is younger than most reported cases and has no bone pain or any skeletal involvement...
2017: Case Reports in Hematology
https://www.readbyqxmd.com/read/29185021/surgical-training-and-standardised-management-guidelines-improved-the-30-day-complication-rate-after-abdominoplasty-for-massive-weight-loss
#10
E Swedenhammar, B Stark, A Hedén Hållstrand, M Ehrström, J Gahm
BACKGROUND: An increasing number of patients need reconstructive surgery after massive weight loss. The hypothesis was that surgical experience together with standardised management guidelines significantly decreases early complication rates after abdominoplasty for massive weight loss. The primary aim was to assess the 30-day complication rate after abdominoplasty following increased surgical training and experience. The secondary aim was to assess whether optimised management guidelines have an impact on the complication rate and patient safety...
November 28, 2017: World Journal of Surgery
https://www.readbyqxmd.com/read/29167426/epigenetic-targeting-of-bromodomain-protein-brd4-counteracts-cancer-cachexia-and-prolongs-survival
#11
Marco Segatto, Raffaella Fittipaldi, Fabrizio Pin, Roberta Sartori, Kyung Dae Ko, Hossein Zare, Claudio Fenizia, Gianpietro Zanchettin, Elisa Sefora Pierobon, Shinji Hatakeyama, Cosimo Sperti, Stefano Merigliano, Marco Sandri, Panagis Filippakopoulos, Paola Costelli, Vittorio Sartorelli, Giuseppina Caretti
Cancer cachexia is a devastating metabolic syndrome characterized by systemic inflammation and massive muscle and adipose tissue wasting. Although it is responsible for approximately one-third of cancer deaths, no effective therapies are available and the underlying mechanisms have not been fully elucidated. We previously identified the bromodomain and extra-terminal domain (BET) protein BRD4 as an epigenetic regulator of muscle mass. Here we show that the pan-BET inhibitor (+)-JQ1 protects tumor-bearing mice from body weight loss and muscle and adipose tissue wasting...
November 22, 2017: Nature Communications
https://www.readbyqxmd.com/read/29135892/-lower-body-lift-in-the-massive-weight-loss-patient-a-new-classification-and-algorithm-for-gluteal-augmentation
#12
Taliah Schmitt, Samer Jabbour, Rani Makhoul, Warren Noel, Anne-Sophie Reguesse, Philippe Levan
BACKGROUND: An often neglected part of the lower body lift procedure is the gluteal region. The objective of this study is to classify the massive weight loss (MWL) patients undergoing a body lift procedure and provide a safe, standardized approach for gluteal augmentation. METHODS: A retrospective review of all body lift procedures performed between January 2012 and January 2017 was conducted. Patients undergoing a lower body lift with or without gluteal augmentation were included for analysis...
November 8, 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/29117298/long-term-quality-of-life-outcomes-after-body-contouring-surgery-phase-iv-results-for-the-body-qol%C3%A2-cohort
#13
Jaco Suijker, Ekaterina Troncoso, Francisca Pizarro, Sofia Montecinos, Galia Villarroel, Cristian Erazo, Juan Pablo Cisternas, Patricio Andrades, Susana Benítez, Sergio Sepúlveda, Stefan Danilla
Background: Body contouring surgery (BCS) is becoming increasing popular for aesthetic and reconstructive purposes, particularly among patients with massive weight loss (MWL). However, data on quality of life (QoL) following the surgery are limited, especially long-term QoL. Objectives: The authors evaluated the effect of BCS on QoL and the durability of this effect over time. Methods: QoL was measured with the Body-QoL® instrument at 3 time points among consecutively treated patients: the day before BCS, 1 to 9 months postoperatively (short term), and 1 to 2...
June 3, 2017: Aesthetic Surgery Journal
https://www.readbyqxmd.com/read/29112748/intermittent-lighting-improves-resilience-of-broilers-during-the-peak-phase-of-sub-clinical-necrotic-enteritis-infection
#14
I Rodrigues, B Svihus, M R Bedford, R Gous, M Choct
Necrotic enteritis, either in its clinical or sub-clinical form is known to cause massive economic losses in the broiler chicken industry. Currently, the use of in-feed antibiotics as growth promoters is discouraged. Therefore, mechanisms to control NE through diet include reduction of digesta viscosity, promotion of lower pH in the gastrointestinal tract (GIT) through acidification of feed, production of short-chain fatty acids and overall stimulation of beneficial bacteria growth. Intermittent lighting programs increase feed retention in the crop and reduce pH in the foregut compartments in comparison with standard commercial lighting programs and therefore may be a valuable, yet underexploited, barrier to prevent the invasion of the GIT by pathogens...
November 3, 2017: Poultry Science
https://www.readbyqxmd.com/read/29110847/symptomatic-pseudo-progression-followed-by-significant-treatment-response-in-two-lung-cancer-patients-treated-with-immunotherapy
#15
Maximilian J Hochmair, Sophia Schwab, Otto C Burghuber, Dagmar Krenbek, Helmut Prosch
In the setting of pseudo-progression in a cancer patient who receives immunotherapeutic treatment, discontinuation of therapy is recommended if the patient is symptomatic. Here, we present two patients with advanced adenocarcinoma of the lung who developed massive tumor growth after initiation of treatment with the anti-PD-1 antibody pembrolizumab. Even though clinical deterioration occurred in the form of severe dyspnea and weight loss, pembrolizumab therapy was continued, as the speed of tumor growth suggested pseudo-progression and the tumors showed marked PD-L1 expression...
November 2017: Lung Cancer: Journal of the International Association for the Study of Lung Cancer
https://www.readbyqxmd.com/read/29089651/pyloric-obstruction-due-to-massive-eosinophilic-infiltration-in-a-young-adult-dog
#16
Alexandros O Konstantinidis, Mathios E Mylonakis, Dimitra Psalla, Nectarios Soubasis, Dimitrios Papadimitriou, Timoleon S Rallis
A 16-month-old dog was presented with chronic vomiting, anorexia, progressive weight loss, and melena. Exploratory laparotomy revealed a massive pyloric eosinophilic infiltration leading to pyloric obstruction that was treated successfully with pylorectomy. This is a novel clinical presentation of eosinophilic gastritis and highlights the need to consider it as a differential diagnosis for pyloric obstruction.
November 2017: Canadian Veterinary Journal. la Revue Vétérinaire Canadienne
https://www.readbyqxmd.com/read/29075821/mastopexy-on-reconstructed-breast-following-massive-weight-loss-an-innovative-technique-using-dermo-capsular-flaps
#17
A Cogliandro, M Barone, G Cassotta, R Salzillo, P Persichetti
BACKGROUND: We have developed a dermo-capsular flap mastopexy technique for patients who have experienced massive weight loss after breast reconstruction. The aim of this technique is to lift the inframammary fold, adequately cover the implant, and remove excess skin, elevating the breast and obtaining symmetry with the contralateral breast. METHODS: Between January 2014 and February 2017, we performed this technique on 20 women who were candidates for second-stage breast reconstruction following nipple-sparing mastectomy...
October 26, 2017: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/29068923/impact-of-patient-subtype-and-surgical-variables-on-abdominoplasty-outcomes-a-12-year-massachusetts-general-hospital-experience
#18
Akhil K Seth, Alex M Lin, William G Austen, Robert H Gilman, Gregory G Gallico, Amy S Colwell
BACKGROUND: The traditional abdominoplasty is one of the most common surgical procedures performed. This study evaluates the impact of different surgical techniques and clinical patient factors on abdominoplasty outcomes. METHODS: A retrospective review of consecutive patients undergoing abdominoplasty was performed. RESULTS: Seven hundred seventy-nine patients with a mean age of 43.7 years and a body mass index of 27 kg/m underwent abdominoplasty...
November 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/29058164/hand-assisted-laparoscopic-hassab-s-procedure-for-esophagogastric-varices-with-portal-hypertension
#19
Takashi Kobayashi, Kohei Miura, Hirosuke Ishikawa, Daiki Soma, Zhengkun Zhang, Takuya Ando, Kizuki Yuza, Yuki Hirose, Tomohiro Katada, Kazuyasu Takizawa, Masayuki Nagahashi, Jun Sakata, Hitoshi Kameyama, Toshifumi Wakai
BACKGROUND: Laparoscopic surgery for patients with portal hypertension is considered to be contraindicated because of the high risk of massive intraoperative hemorrhaging. However, recent reports have shown hand-assisted laparoscopic surgery for devascularization and splenectomy to be a safe and effective method of treating esophagogastric varices with portal hypertension. The aim of this study is to evaluate the efficacy of hand-assisted laparoscopic devascularization and splenectomy (HALS Hassab's procedure) for the treatment of esophagogastric varices with portal hypertension...
October 23, 2017: Surgical Case Reports
https://www.readbyqxmd.com/read/29044362/personal-evolution-in-thighplasty-techniques-for-patients-following-massive-weight-loss
#20
Shelly M Xie, Kevin Small, Ran Stark, Ryan S Constantine, Jordan P Farkas, Jeffrey M Kenkel
Background: Lockwood described the importance of Colles' fascia anchoring in medial thighplasty to reduce morbidity associated with the procedure. However, this maneuver may still have complications including traumatic dissection, prolonged edema, and potential wound healing ramifications form increased tension. Alternatively, we suggest orienting tension in medial thighplasty for massive weight loss (MWL) patients in the horizontal vector rather than a vertical direction, negating the need for Colles' fascia anchoring...
October 16, 2017: Aesthetic Surgery Journal
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