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https://www.readbyqxmd.com/read/29666878/-methemoglobinemia-after-inhalation-of-poppers
#1
U Janssens, S Hillen, T Janssens, J Grafe
BACKGROUND: This case report presents a case of symptomatic methemoglobinemia (MetHb 31.6%) after inhalation of volatile nitrites (poppers). METHODS: The patient's medical history and symptoms are discussed together with pathophysiology of methemoglobinemia, diagnostics, and antidote therapy. Pulse oxymetry, arterial blood gas analysis, and CO-oximetry receive particular attention as well as antidote therapy with methylene blue. RESULTS: The patient was treated successfully with intravenous methylene blue...
April 17, 2018: Medizinische Klinik, Intensivmedizin und Notfallmedizin
https://www.readbyqxmd.com/read/29580615/-sao-2-and-pao-2-mismatch-do-not-forget-hemoglobinopathy
#2
E Virot, S Hirschi, M Oswald, T Degot, M Canuet, A-C Galoisy, L Kiger, S Pissard, R Kessler
INTRODUCTION: Different clinico-biological parameters are used to estimate the amount of oxygen available for the organism. Oxygen saturation measured with pulse oxymetry (SpO2 ), oxygen saturation of arterial blood (SaO2 ) and oxygen partial pressure of the arterial blood (PaO2 ) are the most commonly used. CASE REPORT: We report the case of a patient admitted for investigation of respiratory failure in the context of chronic dyspnea of effort. SpO2 and SaO2 were decreased, though the PaO2 was normal...
March 23, 2018: Revue des Maladies Respiratoires
https://www.readbyqxmd.com/read/29532502/administering-atropine-and-ketamine-before-less-invasive-surfactant-administration-resulted-in-low-pain-scores-in-a-prospective-study-of-premature-neonates
#3
L Bourgoin, L Caeymaex, F Decobert, C Jung, C Danan, X Durrmeyer
AIM: Less invasive surfactant administration (LISA) can avoid tracheal intubation for neonatal respiratory distress syndrome, but can be painful because it requires laryngoscopy. The aim of this study was to assess the efficacy and tolerance of intravenous atropine plus ketamine administration before LISA. METHODS: We conducted a prospective observational study of all premature infants hospitalised in our French neonatal intensive care unit treated with LISA between March 2015 and March 2016...
March 13, 2018: Acta Paediatrica
https://www.readbyqxmd.com/read/29275345/preoxygenation-with-non-invasive-ventilation-versus-high-flow-nasal-cannula-oxygen-therapy-for-intubation-of-patients-with-acute-hypoxaemic-respiratory-failure-in-icu-the-prospective-randomised-controlled-florali-2-study-protocol
#4
Jean-Pierre Frat, Jean-Damien Ricard, Rémi Coudroy, René Robert, Stéphanie Ragot, Arnaud W Thille
INTRODUCTION: Endotracheal intubation in intensive care unit (ICU) is a procedure at high risk of life-threatening complications. Among them, severe oxygen desaturation, usually defined as a drop of pulse oxymetry (SpO2 ) below 80%, is the most common. Preoxygenation enables delaying oxygen desaturation occurring during apnea induced by anaesthetic drugs. Data suggest that non-invasive ventilation (NIV) or high-flow nasal cannula (HFNC) oxygen therapy could further increase PaO2 before intubation procedure and prevent oxygen desaturation episodes as compared with standard oxygen...
December 22, 2017: BMJ Open
https://www.readbyqxmd.com/read/29209787/-different-levels-of-experience-with-anesthetic-agents-of-german-emergency-physicians-results-of-an-online-survey
#5
A Luckscheiter, M Fischer, W Zink
BACKGROUND AND OBJECTIVE: In 2015 practice management guidelines on prehospital emergency anesthesia in adults were published in Germany. The aim of the present study was to evaluate whether emergency physicians follow these guidelines in daily practice and to assess their level of experience with the use of anesthetic agents. MATERIAL AND METHODS: In an online survey the way of induction of preclinical anesthesia (including preoxygenation time and applied monitoring techniques) was assessed with the help of virtual scenarios based on the guidelines...
January 2018: Der Anaesthesist
https://www.readbyqxmd.com/read/28539703/triarylmethyl-radicals-epr-study-of-13-c-hyperfine-coupling-constants
#6
Andrey A Kuzhelev, Victor M Tormyshev, Olga Yu Rogozhnikova, Dmitry V Trukhin, Tatiana I Troitskaya, Rodion K Strizhakov, Olesya A Krumkacheva, Matvey V Fedin, Elena G Bagryanskaya
Triarylmethyl (TAM) radicals are widely used in Electron Paramagnetic Resonance (EPR) spectroscopy as spin labels and in EPR imaging as spin probes for in vivo oxymetry. One of the key advantages of TAMs is extremely narrow EPR line, especially in case of deuterated analogues (~5 μT). Another advantage is their slow spin relaxation even at physiological temperatures allowing, in particular, application of pulsed dipolar EPR methods for distance measurements in biomolecules. In this paper a large series of TAM radicals and their deuterated analogues is synthesized, and corresponding spectroscopic parameters including (13)C hyperfine constants are obtained for the first time...
April 2017: Zeitschrift Für Physikalische Chemie
https://www.readbyqxmd.com/read/28301889/geburtshilfe-an%C3%A3-sthesie-bei-exit-prozedur
#7
REVIEW
Alexander Torossian
The ex utero intrapartum treatment (EXIT) procedure is performed as a part of an extended caesarean section for example to treat fetal airway disorders. For treatment, optimal uterine relaxation is necessary, however utero-placental supply of the fetus has to be guaranteed as well. "Balanced" anesthesia, tocolysis and tight maternal arterial blood pressure control are recommended. Standard fetal monitoring comprises pulse oxymetry and echocardiography. The article describes the physiology and anesthestic goals of the EXIT procedure, discusses alternative anesthesia techniques and gives an outlook on emerging progress...
March 2017: Anästhesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie: AINS
https://www.readbyqxmd.com/read/27909500/cardiac-rhythm-device-threshold-testing-via-pulse-oxymetry
#8
Vladimir Fridman, Cesare Saponieri, Nabil El Sherif, Gioia Turitto
Threshold testing of cardiac rhythm devices is essential to monitoring the proper functioning of such devices (1). However, the currently method of applying multiple ECG leads to the patient is burdensome and time consuming (2). We are presenting a completely new way to perform cardiac rhythm device threshold testing using pulse oximetry. Twenty patients, with varying cardiac rhythm devices and pacing modes, were enrolled and had their atrial and ventricular thresholds tested. A comparison was made between simultaneous threshold determinations via the standard EGM based method and the new pulse oximetry based method...
April 2016: Journal of Atrial Fibrillation
https://www.readbyqxmd.com/read/27904601/evaluation-effects-of-nebulized-gentamicin-in-exacerbation-of-chronic-obstructive-lung-disease
#9
Forogh Soltaninejad, Soleiman Kheiri, Roya Habibian, Arshia Amra, Shahin Asgari-Savadjani
BACKGROUND: Chronic obstructive pulmonary disease (COPD) is a major cause of chronic morbidity and mortality throughout the world. Exacerbation of COPD has negative effect on quality of life. Therapeutic effect of nebulized antibiotics in pulmonary infections has been reported previously. Hence, we evaluated the effect of nebulized gentamicin in acute exacerbation of COPD (AECOPD). MATERIALS AND METHODS: In this clinical trial study, 86 hospitalized patients with AECOPD were divided into two groups for using nebulized gentamicin twice daily (case group) and placebo (control group) for 5 days in addition to standard treatment...
2016: Journal of Research in Medical Sciences: the Official Journal of Isfahan University of Medical Sciences
https://www.readbyqxmd.com/read/27728245/study-of-role-of-pulse-oxymetry-during-nonsedated-upper-gastrointestinal-gi-endoscopic-procedure
#10
S Dasgupta, A L Kakrani, A A Bamanikar, Bhumika Vaishnav
No abstract text is available yet for this article.
January 2016: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/27310989/application-of-co2-waveform-in-the-alveolar-recruitment-maneuvers-of-hypoxemic-patients-during-one-lung-ventilation
#11
RANDOMIZED CONTROLLED TRIAL
Chunshan Dong, Junma Yu, Qi Liu, Chao Wu, Yao Lu
Deterioration of gas exchange during one-lung ventilation (OLV) is caused by both total collapse of the nondependent lung and partial collapse of the dependent lung. Alveolar recruitment maneuver improves lung function during general anesthesia. The objective of this study was to investigate whether there is an indirect relationship between the changes of CO2 expirogram and the selective lung recruitment. To further improve the oxygenation and gas exchange, we compare adjust setting of ventilated parameters based on CO2 expirogram and a preset setting of ventilated parameters during OLV in patients undergoing right-side thoracic surgery...
June 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/26477263/in-vivo-po2-imaging-of-tumors-oxymetry-with-very-low-frequency-electron-paramagnetic-resonance
#12
REVIEW
Boris Epel, Howard J Halpern
For over a century, it has been known that tumor hypoxia, regions of a tumor with low levels of oxygenation, are important contributors to tumor resistance to radiation therapy and failure of radiation treatment of cancer. Recently, using novel pulse electron paramagnetic resonance (EPR) oxygen imaging, near absolute images of the partial pressure of oxygen (pO2) in tumors of living animals have been obtained. We discuss here the means by which EPR signals can be obtained in living tissues and tumors. We review development of EPR methods to image the pO2 in tumors and the potential for the pO2 image acquisition in human subjects...
2015: Methods in Enzymology
https://www.readbyqxmd.com/read/26228110/-the-feasibility-of-screening-for-copd-and-asthma-in-the-general-population
#13
A Palot, D Charpin
INTRODUCTION: There are very few surveys devoted to the prevalence of asthma and COPD in the general population. The Motorola Health System has been developed to make such surveys easier. OBJECTIVES: The main objective was to assess the acceptability and efficacy of the Motorola Health system in collecting health data at home in the context of an epidemiological study of respiratory health. The secondary objective was to determine whether a home-based survey would lead to a higher participation rate than a hospital-based survey...
January 2016: Revue des Maladies Respiratoires
https://www.readbyqxmd.com/read/26135254/patient-posture-and-ileal-intubation-during-colonoscopy-pic-a-randomized-controlled-open-label-trial
#14
Sk Mahiuddin Ahammed, Kshaunish Das, R Sarkar, J Dasgupta, S Bandopadhyay, G K Dhali
BACKGROUND AND AIMS: Patient's posture change is commonly employed by a colonoscopist to achieve complete examination. We studied whether patient's posture (left-lateral decubitus vs supine) influenced the success rate of ileal intubation. PATIENTS AND METHODS: In this prospective open-label randomized study performed in the Endoscopy Suite of a tertiary-care center, all adult outpatients referred for colonoscopy, in whom cecal intubation was achieved and who satisfied predefined inclusion criteria, were randomized to undergo ileal intubation in either of the above two postures...
June 2014: Endoscopy International Open
https://www.readbyqxmd.com/read/25828242/comparison-of-pulse-sequences-for-r1-based-electron-paramagnetic-resonance-oxygen-imaging
#15
COMPARATIVE STUDY
Boris Epel, Howard J Halpern
Electron paramagnetic resonance (EPR) spin-lattice relaxation (SLR) oxygen imaging has proven to be an indispensable tool for assessing oxygen partial pressure in live animals. EPR oxygen images show remarkable oxygen accuracy when combined with high precision and spatial resolution. Developing more effective means for obtaining SLR rates is of great practical, biological and medical importance. In this work we compared different pulse EPR imaging protocols and pulse sequences to establish advantages and areas of applicability for each method...
May 2015: Journal of Magnetic Resonance
https://www.readbyqxmd.com/read/25702425/-effect-of-basic-therapy-on-clinical-symptoms-quality-of-life-and-systemic-inflammation-in-patients-with-chronic-obstructive-pulmonary-disease
#16
I I Baranova, I V Leshchenko
The study included 38 men with moderately severe chronic obstructive pulmonary disease (COPD) (mean age 60.6 ± 10.2 yr) and 42 ones with severe COPD (mean age 61.2 ± 7.2 yr). They were treated with tiotropium bromide, formoterol and beclomethasone dipropionate for 24 weeks (stage 1), TB alone for 12 weeks (stage 2) and TB+formoterol (long-acting bronchodilators, LABD) for another 12 weeks. Each stage was followed by evaluation of COPD symptoms using the St-George's Hospital questionnaire, daily requirements for short-acting beta-2 agonists (SABA), heart rate (HR), forced expiratory volume in the 1st second (FEV-1) before and after SABA test, hemoglobin saturation with oxygen in arterial blood during pulse oxymetry before and after 6 min walking test, blood surfactant protein D level (SP-D)...
2013: Klinicheskaia Meditsina
https://www.readbyqxmd.com/read/25657207/divergent-physiological-responses-in-laboratory-rats-and-mice-raised-at-high-altitude
#17
COMPARATIVE STUDY
Alexandra Jochmans-Lemoine, Gabriella Villalpando, Marcelino Gonzales, Ibana Valverde, Rudy Soria, Vincent Joseph
Ecological studies show that mice can be found at high altitude (HA - up to 4000 m) while rats are absent at these altitudes, and there are no data to explain this discrepancy. We used adult laboratory rats and mice that have been raised for more than 30 generations in La Paz, Bolivia (3600 m), and compared their hematocrit levels, right ventricular hypertrophy (index of pulmonary hypertension) and alveolar surface area in the lungs. We also used whole-body plethysmography, indirect calorimetry and pulse oxymetry to measure ventilation, metabolic rate (O2 consumption and CO2 production), heart rate and pulse oxymetry oxygen saturation (pO2 ,sat) under ambient conditions, and in response to exposure to sea level PO2 (32% O2=160 mmHg for 10 min) and hypoxia (18% and 15% O2=90 and 75 mmHg for 10 min each)...
April 2015: Journal of Experimental Biology
https://www.readbyqxmd.com/read/25303758/spontaneous-breathing-trial-evaluation-in-preterm-newborns-extubation
#18
Lívia Barboza Andrade, Thaís Myrian Aragão Melo, Danielle Ferreira do Nascimento Morais, Marcela Raquel Oliveira Lima, Emídio Cavalcanti Albuquerque, Paula Honório de Melo Martimiano
OBJECTIVE: Neonates mechanic ventilation weaning has become a major clinical challenge, and constitutes a large portion of neonatal intensive care units workload. The spontaneous breathing trial (SBT), performed immediately before extubation, can provide useful information on the patient's spontaneous breathing ability. This study aimed to assess the SBT effectiveness for extubation success prediction in mechanically ventilated preterm infants. METHODS: After Ethics Committee approval, an observational, longitudinal, prospective study was conducted...
June 2010: Revista Brasileira de Terapia Intensiva
https://www.readbyqxmd.com/read/25253897/disordered-breathing-during-sleep-and-exercise-in-idiopathic-pulmonary-fibrosis-and-the-role-of-biomarkers
#19
R N C Lee, E Kelly, G Nolan, S Eigenheer, D Boylan, D Murphy, J Dodd, M P Keane, W T McNicholas
BACKGROUND AND OBJECTIVE: Idiopathic pulmonary fibrosis (IPF) patients report fatigue, possibly reflecting sleep disturbance, but little is known about sleep-related changes. We compared ventilation and gas exchange during sleep and exercise in a cohort of IPF patients, and evaluated associations with selected biological markers. METHODS: Twenty stable IPF patients (aged 67.9 ± 12.3 [SD]) underwent overnight polysomnography following an acclimatization night. Cardiopulmonary exercise testing was performed and inflammatory markers measured including TNF-α, IL-6, CXCL8, C-C motif ligand 18 (CCL-18) and C-reactive protein (CRP) RESULTS: Nine patients had sleep-disordered breathing (SDB) with an apnea-hypopnea frequency (AHI) ≥ 5/h, but only two had Epworth sleepiness score ≥ 10, thus having an obstructive sleep apnea syndrome...
April 2015: QJM: Monthly Journal of the Association of Physicians
https://www.readbyqxmd.com/read/24886350/assessment-of-atropine-sufentanil-atracurium-anaesthesia-for-endotracheal-intubation-an-observational-study-in-very-premature-infants
#20
Xavier Durrmeyer, Sonia Dahan, Pierre Delorme, Sabine Blary, Gilles Dassieu, Laurence Caeymaex, Ricardo Carbajal
BACKGROUND: Premedication before neonatal intubation is heterogeneous and contentious. The combination of a short acting, rapid onset opioid with a muscle relaxant is considered suitable by many experts. The purpose of this study was to describe the tolerance and conditions of intubation following anaesthesia with atropine, sufentanil and atracurium in very premature infants. METHODS: Monocentric, prospective observational study in premature infants born before 32 weeks of gestational age, hospitalised in the NICU and requiring semi-urgent or elective intubation...
2014: BMC Pediatrics
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