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REVIEW
Illari Sechi, Narcisa Muresu, Biagio Di Lorenzo, Laura Saderi, Mariangela Puci, Stefano Aliberti, Ivana Maida, Michele Mondoni, Andrea Piana, Giovanni Sotgiu
Recurrent respiratory papillomatosis (RRP) is a non-malignant disease, characterized by the production of wart-like growths in the respiratory tract, affecting both young people and adults (juvenile-onset recurrent respiratory papillomatosis, JORRP, and adult-onset recurrent respiratory papillomatosis, AORRP, respectively). Infection caused by human papillomavirus (HPV) is known as the main factor involved in RRP development. Complications of RRP may rarely occur, including lung involvement and malignant transformation...
February 28, 2024: Infectious Disease Reports
#2
JOURNAL ARTICLE
Scott S Lee, Nicole Senft Everson, Maureen Sanderson, Rebecca Selove, William J Blot, Stephen King, Karen Gilliam, Suman Kundu, Mark Steinwandel, Sarah J Sternlieb, Qiuyin Cai, Shaneda Warren Andersen, Debra L Friedman, Erin Connors Kelly, Mary Kay Fadden, Matthew S Freiberg, Quinn S Wells, Juan Canedo, Rachel F Tyndale, Robert P Young, Raewyn J Hopkins, Hilary A Tindle
BACKGROUND: The feasibility of precision smoking treatment in socioeconomically disadvantaged communities has not been studied. METHODS: Participants in the Southern Community Cohort Study who smoked daily were invited to join a pilot randomized controlled trial of three smoking cessation interventions: guideline-based care (GBC), GBC plus nicotine metabolism-informed care (MIC), and GBC plus counseling guided by a polygenic risk score (PRS) for lung cancer. Feasibility was assessed by rates of study enrollment, engagement, and retention, targeting > 70% for each...
March 15, 2024: Addiction Science & Clinical Practice
#3
JOURNAL ARTICLE
Meijun Meng, Rui Wei, Yanjun Wu, Ruijie Zeng, Dongling Luo, Yuying Ma, Lijun Zhang, Wentao Huang, Hanshi Zeng, Felix W Leung, Xinqi Qiu, Weihong Sha, Hao Chen
BACKGROUND: In the post-pandemic era, growing apprehension exists regarding the potential sequelae of COVID-19. However, the risks of respiratory diseases following SARS-CoV-2 infection have not been comprehensively understood. This study aimed to investigate whether COVID-19 increases the long-term risk of respiratory illness in patients with COVID-19. METHODS: In this longitudinal, population-based cohort study, we built three distinct cohorts age 37-73 years using the UK Biobank database; a COVID-19 group diagnosed in medical records between January 30th, 2020 and October 30th, 2022, and two control groups, a contemporary control group and a historical control group, with cutoff dates of October 30th, 2022 and October 30th, 2019, respectively...
March 2024: EClinicalMedicine
#4
JOURNAL ARTICLE
Siqi Zhang, Xiaohong Liu, Lixin Zhou, Kai Wang, Jun Shao, Jianyu Shi, Xuan Wang, Jiaxing Mu, Tianrun Gao, Zeyu Jiang, Kezhong Chen, Chengdi Wang, Guangyu Wang
BACKGROUND: Prognosis is crucial for personalized treatment and surveillance suggestion of the resected non-small-cell lung cancer (NSCLC) patients in stage I-III. Although the tumor-node-metastasis (TNM) staging system is a powerful predictor, it is not perfect enough to accurately distinguish all the patients, especially within the same TNM stage. In this study, we developed an intelligent prognosis evaluation system (IPES) using pre-therapy CT images to assist the traditional TNM staging system for more accurate prognosis prediction of resected NSCLC patients...
November 2023: EClinicalMedicine
#5
JOURNAL ARTICLE
Karly I Cini, Nisaa R Wulan, Dorothea Dumuid, Alifah Nurjannah Triputri, Iffat Abbsar, Luo Li, Diandra A Priambodo, Grace E Sameve, Artha Camellia, Kate L Francis, Susan M Sawyer, George C Patton, Ansariadi Ansariadi, Peter S Azzopardi
BACKGROUND: Non-communicable diseases (NCDs) such as cancer, diabetes, heart disease, mental disorder and chronic lung conditions are the leading cause of death and disability in Indonesia. Adolescence is when risks for NCDs emerge and it is also an important life stage for intervention, yet young people are often at the margins of NCD policy and actions. This study aimed to understand how policies and actions should address NCD risks (tobacco smoking, inadequate physical activity, and diet) for adolescents in Indonesia, and how young people can be meaningfully involved...
November 2023: Lancet Reg Health Southeast Asia
#6
JOURNAL ARTICLE
Rebecca Landy, Li C Cheung, Corey D Young, Anil K Chaturvedi, Hormuzd A Katki
BACKGROUND: This report quantifies counteracting effects of quit-years and concomitant aging on lung cancer risk, especially on exceeding 15 quit-years, when the US Preventive Services Task Force (USPSTF) recommends curtailing lung-cancer screening. METHODS: Cox models were fitted to estimate absolute lung cancer risk among Prostate, Lung, Colorectal and Ovarian Cancer Screening Trial (PLCO) and National Lung Screening Trial (NLST) participants who ever smoked. Absolute lung cancer risk and gainable years of life from screening for individuals aged 50 to 80 in the US-representative National Health Interview Survey (NHIS) 2015-2018 who ever smoked were projected...
November 1, 2023: Cancer
#7
JOURNAL ARTICLE
Alexandra L Potter, Allison L Rosenstein, Keervani Kandala, Shivaek Venkateswaran, Mathew V Kiang, Olugbenga Okusanya, Hugh G Auchincloss, Linda W Martin, Yolonda L Colson, Chi-Fu Jeffrey Yang
OBJECTIVES: To evaluate if there is a shortage of thoracic surgeons in the U.S. and whether any potential shortage is impacting lung cancer treatment and outcomes. DESIGN: Using the U.S. Area Health Resources File and Surveillance Epidemiology End Results database, we assessed the number of cardiothoracic surgeons per 100,000 people and the number of stage I NSCLC diagnoses in the U.S. in 2010 versus 2018. Changes in the percentage of patients diagnosed with stage I NSCLC who underwent surgery and stereotactic body radiotherapy (SBRT) and changes in overall survival of patients with stage I NSCLC from 2010-2018 in the National Cancer Database were evaluated using multivariable logistic regression and Cox proportional hazards modeling...
September 14, 2023: Journal of Thoracic and Cardiovascular Surgery
#8
JOURNAL ARTICLE
Yi Xiao, Hongmei He, Ling Xiang, Haitao Gu, Zhiquan Xu, Haoyun Luo, Xiaorui Ren, Bo Li, Qi Wei, Zhiyong Zhu, He Zhou, Yunhao Tang, Zhihang Zhou, Linglong Peng, Yaxu Wang, Yahui Jiang
BACKGROUND: Sulfur microbial diet (SMD), related to the enrichment of sulfur-metabolizing gut bacteria, has been confirmed to be linked to an elevated risk of early-onset colorectal adenoma in young females. However, it remains unclear whether SMD is associated with the risk of colorectal adenoma in older people, who are at greater risk for colorectal cancer. METHODS: All data on participants in this study were retrieved from the intervention arm of the Prostate, Lung, Colorectal, and Ovarian (PLCO) cancer screening test...
2023: Frontiers in Nutrition
#9
JOURNAL ARTICLE
Kate Parker, Sarah Colhoun, Karen Bartholomew, Peter Sandiford, Chris Lewis, David Milne, Mark McKeage, Rawiri McKree Jansen, Kwun M Fong, Henry Marshall, Martin Tammemägi, Nicole M Rankin, Sandra Hotu, Robert Young, Raewyn Hopkins, Natalie Walker, Rachel Brown, Sue Crengle
Lung cancer screening can significantly reduce mortality from lung cancer. Further evidence about how to optimize lung cancer screening for specific populations, including Aotearoa New Zealand (NZ)'s Indigenous Māori (who experience disproportionately higher rates of lung cancer), is needed to ensure it is equitable. This community-based, pragmatic cluster randomized trial aims to determine whether a lung cancer screening invitation from a patient's primary care physician, compared to from a centralized screening service, will optimize screening uptake for Māori...
2023: PloS One
#10
JOURNAL ARTICLE
Rebekah Laidsaar-Powell, Phyllis Butow, Bernadette Bea Brown, Kimberley Mander, Jane Young, Emily Stone, Venessa Chin, Emily Banks, Chloe Yi Shing Lim, Nicole M Rankin
PURPOSE: Lung cancer remains underrepresented in cancer survivorship research. This study aimed to understand survivors' physical/psychological challenges, experiences of immunotherapy (IO) and targeted therapy (TT), and psychological adjustment through application of the Roberts et al. (2017) advanced cancer adaptation of Folkman and Greer's appraisal and coping model. METHODS: Adults 6-24 months post-initial treatment completion were recruited via an Australian cohort study...
July 27, 2023: Journal of Cancer Survivorship: Research and Practice
#11
JOURNAL ARTICLE
So Young Kim, Hyo Geun Choi, Yoo Hwan Kim, Mi Jung Kwon, Joo-Hee Kim, Heui Seung Lee, Ji Hee Kim
Despite growing epidemiological evidence, the relationship between Parkinson's disease (PD) and cancer has not been conclusively demonstrated, and related studies are scarce in the Asian population. We aimed to determine the association between PD and subsequent development of various cancers from longitudinal data of a representative sample of Korean adults aged ≥40 years. We retrospectively identified 8381 patients diagnosed with PD from 2002 to 2019 using claims data among 514,866 people of random samples from the Korean National Health Insurance database...
July 22, 2023: NPJ Parkinson's Disease
#12
REVIEW
Pavitra Varaganti, Viswanath Buddolla, Buddolla Anantha Lakshmi, Young-Joon Kim
A glycosylphosphatidylinositol (GPI)-anchored glycoprotein called the folate receptor 1 (FOLR1) facilitates the transportation of folate by mediating receptor-mediated endocytosis in response to ligand binding. While FOLR1 expression is typically restricted to the apical surfaces of the epithelium in the lung, kidney, and choroid plexus in healthy people, it is overexpressed in a number of solid tumours, including high-grade osteosarcoma, breast cancer, ovarian cancer, and non-small cell lung cancer. As a result, FOLR1 has become an attractive target for cancer detection and therapy, particularly for cancers that affect women...
May 25, 2023: Life Sciences
#13
JOURNAL ARTICLE
Chaozheng Zhou, Shengkun Peng, Anqi Lin, Aimin Jiang, Yuanxi Peng, Tianqi Gu, Zaoqu Liu, Quan Cheng, Jian Zhang, Peng Luo
BACKGROUND: With the increasing use of immune checkpoint inhibitors (ICIs) for tumour immunotherapy, the immune-related adverse events (irAEs) caused by their collateral effect on the immune system pose a key challenge for the clinical application of ICIs. Psychiatric adverse events are a class of adverse events associated with ICIs that are realistically observed in the real world. We aim to provide a comprehensive study and summary of psychiatric adverse events associated with ICIs...
May 2023: EClinicalMedicine
#14
JOURNAL ARTICLE
Jingjing Xia, Hong Li, Ruirui Zhang, Jipeng Wang
Lung cancer is rare in young people, but the incidence and mortality are on the rise. We retrospectively analyzed the data of young patients aged ≤45 years diagnosed as lung cancer in our hospital from 2014 to 2021. The purpose was to explore the clinicopathological characteristics of young patients, and the risk factors affecting overall survival (OS) time. The results showed that the young patients were mainly female, had no smoking history, asymptomatic at initial diagnosis, with a high proportion of adenocarcinoma and stage I-II...
2023: Open Medicine (Warsaw, Poland)
#15
REVIEW
Philip J Landrigan, Hervé Raps, Maureen Cropper, Caroline Bald, Manuel Brunner, Elvia Maya Canonizado, Dominic Charles, Thomas C Chiles, Mary J Donohue, Judith Enck, Patrick Fenichel, Lora E Fleming, Christine Ferrier-Pages, Richard Fordham, Aleksandra Gozt, Carly Griffin, Mark E Hahn, Budi Haryanto, Richard Hixson, Hannah Ianelli, Bryan D James, Pushpam Kumar, Amalia Laborde, Kara Lavender Law, Keith Martin, Jenna Mu, Yannick Mulders, Adetoun Mustapha, Jia Niu, Sabine Pahl, Yongjoon Park, Maria-Luiza Pedrotti, Jordan Avery Pitt, Mathuros Ruchirawat, Bhedita Jaya Seewoo, Margaret Spring, John J Stegeman, William Suk, Christos Symeonides, Hideshige Takada, Richard C Thompson, Andrea Vicini, Zhanyun Wang, Ella Whitman, David Wirth, Megan Wolff, Aroub K Yousuf, Sarah Dunlop
BACKGROUND: Plastics have conveyed great benefits to humanity and made possible some of the most significant advances of modern civilization in fields as diverse as medicine, electronics, aerospace, construction, food packaging, and sports. It is now clear, however, that plastics are also responsible for significant harms to human health, the economy, and the earth's environment. These harms occur at every stage of the plastic life cycle, from extraction of the coal, oil, and gas that are its main feedstocks through to ultimate disposal into the environment...
2023: Annals of Global Health
#16
REVIEW
Tanisha Basu, Ashley Selman, Arubala P Reddy, P Hemachandra Reddy
Obesity is a growing health concern in today's society. Current estimates indicate that obesity occurs in both adults and young people. Recent research also found that the Hispanic population in the U.S. is 1.9 times more likely to be overweight as compared to their non-Hispanic population. Obesity is a multifactorial disease that has a variety of causes. All current treatment options incorporate dietary changes aimed at establishing a negative energy balance. According to current scientific research, multiple factors are involved with the development of obesity, including genetic, biochemical, psychological, environmental, behavioral, and socio-demographic factors...
February 13, 2023: Antioxidants (Basel, Switzerland)
#17
JOURNAL ARTICLE
Maryam O Alarfaj, Munif M Alshammari, Hanan A Albenayyan, Amar A Alonazi, Abdullah A Alkhateeb, Abdulaziz Al Taisan
Globally, it is known that smoking can cause a variety of diseases. Studies have shown that smoking not only causes heart and lung diseases but is also strongly related to ocular diseases which could lead to blindness. This study aims to assess the level of awareness of blindness related to smoking in young people in Saudi Arabia. This is a descriptive cross-sectional study conducted among the young population in Saudi Arabia. A self-administered questionnaire was distributed using an online platform that includes socio-demographic data, education level, smoking status, and knowledge of the harmful effect of smoking like lung and cardiac diseases, including blindness...
October 2022: Curēus
#18
JOURNAL ARTICLE
Jee Hyun Kim, Kyoung Hee Oh, Hye Young Shin, Jae Kwan Jun
Background: Korean society has faced challenges in communicating with cancer patients about false information related to complementary alternative medicine. As the situation has become severe with the 2020 fenbendazole scandal, the demand for reliable information from health authorities has increased. Objectives: This study aimed to examine patients' acquisition patterns and perception of false information by presenting empirical evidence to help health authorities enable effective preemptive responses in the cancer communication context...
2022: Frontiers in Oncology
#19
JOURNAL ARTICLE
Lin Zhou, Huiwu Li, Shuhui Yang
Adenocarcinoma is the most common histological type of lung cancer in adolescents and young adults (AYAs; ˂50 years of age). However, few clinical trials that have investigated systematic treatments regard AYAs as a special cohort, and the differences in progression-free survival (PFS) and overall survival (OS) between AYAs and older adults is still unclear. The present study compared clinical characteristics, targetable genomic mutations, toxicity, efficacy and prognostic response to systematic treatments in AYAs (n=251) and older adults (n=1,098) who were diagnosed with lung adenocarcinoma between January 2013 and December 2017 at YueBei People's Hospital (Shaoguan, China)...
October 2022: Oncology Letters
#20
JOURNAL ARTICLE
Saloni Bhatia, Padmini Gokhale, Teesta Katte, Shreeshanthi Acharya, Avinash Arvind Rasalkar, Soumya Vidapanakal, Ram Manas, Sampath Chinnam, Prathibha Narayanan, Ashok Kumar Shettihalli, Vijayakumar Kadappa, Divijendra Natha Reddy Sirigiri
Severe acute respiratory syndrome involving corona virus-2 (SARS-CoV-2) has been implied to cause COVID-19 disease, leading to an unprecedented health emergency across the globe with a staggering figure of mortality rate. Measures to control the pandemic are pushing the economy into a tailspin, putting burden not only on the individuals but also on the nations. Despite the widespread infection rates, young people have shown better recovery rate while COVID-19 symptoms are more pronounced in elderly and people with comorbid conditions such as diabetes, cardiac and respiratory diseases...
October 11, 2022: ACS Omega
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