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https://www.readbyqxmd.com/read/28424992/intravitreal-anti-vegf-treatment-for-choroidal-neovascularization-secondary-to-punctate-inner-choroidopathy
#1
T Barth, F Zeman, H Helbig, M-A Gamulescu
PURPOSE: To assess the outcome of patients with choroidal neovascularization (CNV) secondary to punctate inner choroidopathy (PIC) receiving intravitreal anti-VEGF (vascular endothelial growth factor) injections. METHODS: Sixteen eyes of 16 patients diagnosed with CNV secondary to PIC were retrospectively assessed. RESULTS: Eleven women and five men with a mean age of 35 years (SD 11, range 16-56 years) received intravitreal anti-VEGF for PIC-related CNV...
April 19, 2017: International Ophthalmology
https://www.readbyqxmd.com/read/28297030/how-to-differentiate-myopic-choroidal-neovascularization-idiopathic-multifocal-choroiditis-and-punctate-inner-choroidopathy-using-clinical-and-multimodal-imaging-findings
#2
Rosa Dolz-Marco, Howard F Fine, K Bailey Freund
No abstract text is available yet for this article.
March 1, 2017: Ophthalmic Surgery, Lasers & Imaging Retina
https://www.readbyqxmd.com/read/28253223/observation-and-clinical-pattern-in-patients-with-white-dot-syndromes-the-role-of-color-photography-in-monitoring-ocular-changes-in-long-term-observation
#3
Joanna Brydak-Godowska, Joanna Gołębiewska, Monika Turczyńska, Joanna Moneta-Wielgoś, Agnieszka Samsel, Piotr K Borkowski, Michał Ciszek, Agnieszka Płonecka-Rodzoch, Aleksandra Kużnik-Borkowska, Joanna Ciszewska, Elżbieta Makomaska-Szaroszyk, Lidia B Brydak, Dariusz Kęcik
BACKGROUND The aim of this study was to assess the clinical course and distinctive features of different white dot syndromes (WDS) in patients attending the Ophthalmology Department, Medical University of Warsaw in the years 1995-2015. MATERIAL AND METHODS Sixty-two (62) patients (43 females and 19 males), aged 18 to 77 years, referred with a WDS were included in this prospective study, with observation period ranging from 5 months to 16 years. All patients underwent a complete ophthalmological examination and multimodal imaging studies...
March 2, 2017: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/28097335/renaming-of-acute-posterior-multifocal-placoid-pigment-epitheliopathy-apmppe-to-acute-multifocal-placoid-choroidopathy-amp-c
#4
Alice Yang Zhang, Ian C Han, Morton F Goldberg
No abstract text is available yet for this article.
March 1, 2017: JAMA Ophthalmology
https://www.readbyqxmd.com/read/28067720/swept-source-optical-coherence-tomography-evaluation-of-chorioretinal-changes-in-hypertensive-choroidopathy-related-to-hellp-syndrome
#5
Daniel Velazquez-Villoria, Pablo Marti Rodrigo, Maria L DeNicola, Miguel A Zapata Vitori, Antonio Segura García, Jose García-Arumí
PURPOSE: To report a case of hypertensive choroidopathy with detailed chorioretinal images obtained using swept source optical coherence tomography. METHODS: We report the case of a 36-year-old pregnant woman who presented with extensive bilateral exudative retinal detachments (visual acuity of hands movement bilaterally), high blood pressure, and severe alteration of the laboratory test results resulting in the diagnosis of HELLP syndrome. The baby was delivered by emergency cesarean section and the patient was hospitalized in the intensive care unit...
January 6, 2017: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/28050729/acute-lupus-choroidopathy-multimodal-imaging-and-differential-diagnosis-from-central-serous-chorioretinopathy
#6
Murat Hasanreisoglu, Gokcen D Gulpinar Ikiz, Hamit Kucuk, Ozkan Varan, Sengul Ozdek
IMPORTANCE: Systemic lupus erythematosus (SLE) is a thoroughly examined multi-organ disease whose common ocular complications are also well documented. However, SLE choroidopathy, being a rare ocular complication, is needed to be better understood, in order to make the differential diagnosis from clinical conditions such as central serous chorioretinopathy and provide adequate prompt treatment. OBJECTIVE: To provide a clear understanding for the clinical course of SLE choroidopathy by the help of enhanced depth imaging optical coherence tomography, fluorescein angiography, and indocyanine angiography...
January 3, 2017: International Ophthalmology
https://www.readbyqxmd.com/read/28008140/choroidal-microvascular-proliferation-secondary-to-diabetes-mellitus
#7
Rui Hua, Qing Li, Ian Yat Hin Wong, Hong Ning, Hailin Wang
Diabetes is a common endocrine disorder associated with peripheral microvascular diseases such as proliferative retinal microangiopathy (or diabetic retinopathy), which may lead to blindness. Unfortunately, diabetic microvascular abnormalities in the choroid are underestimated in clinical practice. Recent literature has revealed that the severity of diabetic retinopathy is aggravated by choroidopathy resulting from hyperglycemia. Here, we introduce a case of diabetic retinopathy with choroidal neovascularization membrane but without signs of retinal microvascular proliferation or drusen...
January 10, 2017: Oncotarget
https://www.readbyqxmd.com/read/27994812/idiopathic-multifocal-choroiditis
#8
REVIEW
Ali Tavallali, Lawrence A Yannuzzi
Idiopathic multifocal choroiditis (MFC) and/or punctate inner choroidopathy (PIC) describe a chronic progressive bilateral inflammatory chorioretinopathy that predominantly affect healthy myopic white women with no known associated systemic or ocular diseases. The principal sites of involvement are the retinal pigment epithelium (RPE) and outer retinal spaces; the choroid is not affected during the active phase of the disease. Idiopathic MFC with atrophy is a recently described variant. Although there is no generally accepted standard treatment, anti-inflammatory and anti-VEGF (vascular endothelial growth factor) agents are necessary in the acute stage to control the inflammation and choroidal neovascularization (CNV)...
October 2016: Journal of Ophthalmic & Vision Research
https://www.readbyqxmd.com/read/27990740/hypertensive-eye-disease-a-review
#9
REVIEW
Samantha Fraser-Bell, Richard Symes, Anagha Vaze
Hypertension is a risk factor for a number of vision-threatening eye conditions including retinal vascular occlusion, retinal macroaneurysm and non arteritic anterior ischaemic optic neuropathy. In addition, hypertension may exacerbate the vision-threatening effects of diabetic retinopathy and has been implicated in the pathogenesis of age-related macular degeneration. The effects of sustained hypertension are directly visible in the eye as hypertensive retinopathy and choroidopathy, reflecting a pathological process occurring throughout the body...
January 2017: Clinical & Experimental Ophthalmology
https://www.readbyqxmd.com/read/27977842/optical-coherence-tomography-angiography-for-detecting-choroidal-neovascularization-secondary-to-punctate-inner-choroidopathy
#10
Shintaro Nakao, Yoshihiro Kaizu, Yuji Oshima, Taiji Sakamoto, Tatsuro Ishibashi, Koh-Hei Sonoda
Punctate inner choroidopathy (PIC) is a relatively uncommon inflammatory multifocal chorioretinopathy that predominantly affects young, myopic women. Subfoveal choroidal neovascularization (CNV) often leads to rapid loss of sight. Fluorescein angiography (FA) and indocyanine green angiography (ICGA) remain the existing gold standards for CNV diagnosis. However, these methods are invasive and time-consuming. Recently, optical coherence tomography angiography (OCTA) has been used more frequently as an adjunct to FA/ICGA...
December 1, 2016: Ophthalmic Surgery, Lasers & Imaging Retina
https://www.readbyqxmd.com/read/27929712/dengue-maculopathy-associated-with-choroidopathy-and-pseudohypopyon-a-case-series
#11
Christina W K Ng, P Y Tai, Shelina Oli Mohamed
No abstract text is available yet for this article.
December 8, 2016: Ocular Immunology and Inflammation
https://www.readbyqxmd.com/read/27857759/stem-cell-ophthalmology-treatment-study-scots-improvement-in-serpiginous-choroidopathy-following-autologous-bone-marrow-derived-stem-cell-treatment
#12
Jeffrey N Weiss, Susan C Benes, Steven Levy
We report results in a 77-year-old male patient with visual loss from long-standing serpiginous choroidopathy treated with bone marrow derived stem cells (BMSC) within the Stem Cell Ophthalmology Treatment Study (SCOTS). SCOTS is an Institutional Review Board approved clinical trial and the largest ophthalmology stem cell study registered at the National Institutes of Health to date (ClinicalTrials.gov Identifier: NCT01920867). Eight months after treatment by a combination of retrobulbar, subtenon, intravitreal and intravenous injection of BMSC, the patient's best corrected Snellen acuity improved from 20/80(-) to 20/60(+1) in the right eye and from 20/50(-) to 20/20(-3) in the left eye...
September 2016: Neural Regeneration Research
https://www.readbyqxmd.com/read/27751823/punctate-inner-choroidopathy-a-review
#13
REVIEW
Dana Ahnood, Savitha Madhusudhan, Marie D Tsaloumas, Nadia K Waheed, Pearse A Keane, Alastair K Denniston
Punctate inner choroidopathy (PIC), an idiopathic inflammatory multifocal chorioretinopathy that predominantly affects young myopic women, appears to be relatively rare, but there are limited data to support accurate estimates of prevalence, and it is likely that the condition is underdiagnosed. The etiological relationship between PIC and other conditions within the "white dot syndromes" group remains uncertain. We, like others, would suggest that PIC and multifocal choroiditis with panuveitis represent a single disease process that is modified by host factors (including host immunoregulation) to cause the range of clinical phenotypes seen...
March 2017: Survey of Ophthalmology
https://www.readbyqxmd.com/read/27729795/combined-treatment-in-punctate-inner-choroidopathy
#14
Barbara Terelak-Borys, Katarzyna Zagajewska, Irmina Jankowska-Lech, Piotr Tesla, Iwona Grabska-Liberek
PURPOSE: The purpose of this study was to describe a combination treatment for choroidal neovascular (CNV) membrane, secondary to punctate inner choroidopathy (PIC). PATIENT AND METHODS: A 44-year-old female patient was diagnosed with PIC complicated by the development of recurrent juxtafoveal neovascular membrane. The treatment included a sequence of monotherapy regimens: systemic steroid therapy, photodynamic therapy, and intravitreal injections of vascular endothelial growth factor (VEGF) inhibitor (anti-VEGF)...
2016: Therapeutics and Clinical Risk Management
https://www.readbyqxmd.com/read/27685502/retinal-detachment-associated-with-peripheral-tear-of-the-retinal-pigment-epithelium-in-pachychoroid-spectrum-disease
#15
Mikel Mikhail, Nour Nofal, Mikael Sebag
PURPOSE: To describe a rare case of an exudative retinal detachment associated with a peripheral tear of the retinal pigment epithelium in a young myopic pachychoroid eye. METHODS: Clinical case report and literature review. Imaging was obtained with color fundus photography, spectral domain optical coherence tomography, fluorescein angiography, and fluorescein angiography. RESULTS: A 33-year-old white man presented with an exudative choroidopathy resulting in an exudative neurosensory detachment, associated with peripheral retinal pigment epithelium tears...
January 2017: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/27662233/why-the-dots-are-black-only-in-the-late-phase-of-the-indocyanine-green-angiography-in-multiple-evanescent-white-dot-syndrome
#16
Alain Gaudric, Sarah Mrejen
PURPOSE: To determine what retinal layer is primarily involved in multiple evanescent white dot syndrome compared with acute posterior multifocal placoid pigment epitheliopathy using multimodal imaging including indocyanine green angiography. METHODS: Color fundus photographs and fluorescein angiography, ICGA and spectral domain optical coherence tomography images of two typical acute cases, one of acute posterior multifocal placoid pigment epitheliopathy and one of multiple evanescent white dot syndrome, were assessed and compared...
January 2017: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/27637276/extensive-choroidal-infarction-in-a-case-of-mixed-essential-cryoglobulinaemia-in-a-postpartum-female
#17
Brijesh Takkar, Shorya Vardhan Azad, Uma Kumar, Pradeep Venkatesh
A case of mixed essential cryoglobulinaemia resulting in massive choroidal infarction and irreversible vision loss in a postpartum female is discussed. Cryoglobulinaemia can rarely involve ocular vessels and, in this case, was adjunctive to mild hypertension in causing acute choroidopathy. Although the systemic condition of the patient improved after steroids and immunosuppressive agents, the visual loss was permanent.
September 16, 2016: BMJ Case Reports
https://www.readbyqxmd.com/read/27555066/punctate-inner-choroidopathy-complicated-with-exudative-neurosensory-detachment-a-favourable-response-to-treatment-with-systemic-corticosteroids-and-intravitreal-ranibizumab
#18
M Roca, M Menezo, J M Ronchera, J M Esteban, B Roca
CASE REPORT: Punctate inner choroidopathy (PIC) is a variant of multifocal choroiditis that principally affects young and healthy women. A case of this condition is described in a woman who presented with a scotoma as the main complaint. Four months after the diagnosis of PIC, she developed an exudative neurosensory detachment associated with an active focus of juxtafoveal choroiditis. Finally, with systemic corticosteroids and intravitreal ranibizumab, she made excellent progress. DISCUSSION: Intravitreal ranibizumab, associated with systemic corticosteroids, may be an effective treatment for exudative neurosensory detachment complicating PIC...
August 20, 2016: Archivos de la Sociedad Española de Oftalmología
https://www.readbyqxmd.com/read/27545332/viewing-the-choroid-where-we-stand-challenges-and-contradictions-in-diabetic-retinopathy-and-diabetic-macular-oedema
#19
António Campos, Elisa J Campos, João Martins, António Francisco Ambrósio, Rufino Silva
Diabetic macular oedema (DMO) is the leading cause of vision loss in the working-age population. Blood-retinal barrier (BRB) dysfunction in diabetic retinopathy (DR), mainly at the level of the retinal vessels, has long been related with leakage and fluid accumulation, leading to macular oedema. However, the nourishment of the macula is provided by the choroid and a diabetic choroidopathy has been described. Therefore, there has been a growing interest in studying the role of the choroid in the pathophysiology of DR and DMO, mainly by optical coherence tomography (OCT)...
August 22, 2016: Acta Ophthalmologica
https://www.readbyqxmd.com/read/27540310/retinal-vascular-changes-in-hypertensive-patients-in-ibadan-sub-saharan-africa
#20
Sunday Tunji Oluleye, Bolutife Ayokunu Olusanya, Abiodun Moshood Adeoye
BACKGROUND: Earlier studies in Nigeria reported the rarity of retinal vascular changes in hypertensives. The aim of this study was to describe the various retinal vascular changes in the hypertensive patients of Nigeria. PATIENTS AND METHODS: Nine hundred and three hypertensive patients were studied. This study was approved by the ethical and research committee of the University of Ibadan and University College Hospital, Ibadan, Nigeria. Blood pressure and anthropometric measurements were measured...
2016: International Journal of General Medicine
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