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bipolar disorder RCT 2015

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https://www.readbyqxmd.com/read/28025928/effectiveness-of-the-dader-method-for-pharmaceutical-care-on-patients-with-bipolar-i-disorder-results-from-the-emdader-tab-study
#1
Andrea Salazar-Ospina, Pedro Amariles, Jaime A Hincapié-García, Sebastián González-Avendaño, Dora M Benjumea, Maria José Faus, Luis F Rodriguez
BACKGROUND: Bipolar I disorder (BD-I) is a chronic illness characterized by relapses alternating with periods of remission. Pharmacists can contribute to improved health outcomes in these patients through pharmaceutical care in association with a multidisciplinary health team; however, more evidence derived from randomized controlled trials (RCTs) is needed to demonstrate the effect of pharmaceutical care on patients with BD-I. OBJECTIVE: To assess the effectiveness of a pharmaceutical intervention using the Dader Method on patients with BD-I, measured by the decrease in the number of hospitalizations, emergency service consultations, and unscheduled outpatient visits from baseline through 1 year of follow-up...
January 2017: Journal of Managed Care & Specialty Pharmacy
https://www.readbyqxmd.com/read/27976370/droperidol-for-psychosis-induced-aggression-or-agitation
#2
REVIEW
Mariam A Khokhar, John Rathbone
BACKGROUND: People experiencing acute psychotic illnesses, especially those associated with agitated or violent behaviour, may require urgent pharmacological tranquillisation or sedation. Droperidol, a butyrophenone antipsychotic, has been used for this purpose in several countries. OBJECTIVES: To estimate the effects of droperidol, including its cost-effectiveness, when compared to placebo, other 'standard' or 'non-standard' treatments, or other forms of management of psychotic illness, in controlling acutely disturbed behaviour and reducing psychotic symptoms in people with schizophrenia-like illnesses...
15, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27955680/-walk-this-way-a-pilot-of-a-health-coaching-intervention-to-reduce-sedentary-behaviour-and-increase-low-intensity-exercise-in-people-with-serious-mental-illness-study-protocol-for-a-randomised-controlled-trial
#3
Julie Williams, Brendon Stubbs, Fiona Gaughran, Tom Craig
BACKGROUND: People with serious mental illness (SMI) (psychosis, bipolar disorder and major depressive disorder) experience a considerable risk of premature mortality because of cardiovascular disease. Recent research has demonstrated that this population spends almost 13 h per day being sedentary. Sedentary behaviour is an independent risk factor for cardiovascular disease and mortality. Given the potential for physical activity to improve health and well-being in people with SMI, we developed a pilot randomised controlled trial (RCT) to evaluate a coaching intervention aimed at reducing sedentary behaviour and increasing physical activity in people with SMI...
December 12, 2016: Trials
https://www.readbyqxmd.com/read/27668891/interventions-to-encourage-uptake-of-cancer-screening-for-people-with-severe-mental-illness
#4
Elizabeth A Barley, Rohan D Borschmann, Paul Walters, Andre Tylee
BACKGROUND: Adults with severe mental illness (i.e. schizophrenia or other related psychotic disorders and bipolar disorder) can be at greater risk of cancer than those without severe mental illness (SMI). Early detection of cancer through screening is effective in improving patient outcomes including death. However, people with SMI are less likely than others to take up available cancer screening. OBJECTIVES: To determine the effectiveness of interventions targeted at adults with SMI, or their carers or health professionals, and aimed at increasing the uptake of cancer screening tests for which the adults with SMI are eligible...
September 26, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27226262/blue-blocking-glasses-as-additive-treatment-for-mania-a-randomized-placebo-controlled-trial
#5
Tone Eg Henriksen, Silje Skrede, Ole B Fasmer, Helle Schoeyen, Ieva Leskauskaite, Jeanette Bjørke-Bertheussen, Jörg Assmus, Børge Hamre, Janne Grønli, Anders Lund
OBJECTIVES: The discovery of the blue lightsensitive retinal photoreceptor responsible for signaling daytime to the brain suggested that light to the circadian system could be inhibited by using blue-blocking orange tinted glasses. Blue-blocking (BB) glasses are a potential treatment option for bipolar mania. We examined the effectiveness of BB glasses in hospitalized patients with bipolar disorder in a manic state. METHODS: In a single-blinded, randomized, placebo-controlled trial (RCT), eligible patients (with bipolar mania; age 18-70 years) were recruited from five clinics in Norway...
May 2016: Bipolar Disorders
https://www.readbyqxmd.com/read/26995361/effectiveness-of-illness-management-and-recovery-imr-in-the-netherlands-a-randomised-clinical-trial
#6
RANDOMIZED CONTROLLED TRIAL
Bert-Jan Roosenschoon, Cornelis L Mulder, Mathijs L Deen, Jaap van Weeghel
BACKGROUND: Illness Management and Recovery (IMR) is intended to provide a structured psychosocial programme that helps to manage the disabling effects of severe mental illnesses such as schizophrenia and bipolar disorders. It is curriculum based and aims to improve different aspects of illness management and recovery through interventions such as goal-setting, psycho-education, coping and social skills training. Its overall aim is to improve illness outcomes and support subjective and objective recovery...
March 19, 2016: BMC Psychiatry
https://www.readbyqxmd.com/read/26359219/safety-and-tolerability-of-anticonvulsant-medication-in-bipolar-disorder
#7
REVIEW
Eva Maria Pichler, Georg Hattwich, Heinz Grunze, Moritz Muehlbacher
INTRODUCTION: Anticonvulsants (AC) are widely used and recommended as a treatment option in different phases of bipolar disorder (BD). In contrast to ample evidence for efficacy in acute mania, there is generally less unambiguous evidence for maintenance treatment or bipolar depression, and data on long-term tolerability in BD are sparse, although this varies greatly between different compounds. This review summarizes the clinically relevant tolerability and safety profile of ACs commonly used for the treatment of BD based on findings from randomized controlled trials (RCT)...
2015: Expert Opinion on Drug Safety
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