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https://www.readbyqxmd.com/read/29161662/deiodination-of-iopamidol-by-zero-valent-iron-zvi-enhances-formation-of-iodinated-disinfection-by-products-during-chloramination
#1
Huiyu Dong, Zhimin Qiang, Junfeng Lian, Jin Li, Jianwei Yu, Jiuhui Qu
Iodinated X-ray contrast media (ICM) is considered as one of iodine sources for formation of toxic iodinated disinfection byproducts (I-DBPs) during disinfection. This study investigated transformation of a typical ICM, iopamidol (IPM) by zero valent iron (ZVI) and the effect of transformation on the formation of I-DBPs during chloramination. It was found that the presence of ZVI could deiodinate IPM into I(-) and the transformation of IPM exhibited a pseudo-first-order kinetics. Acidic circumstance, SO4(2-), Cl(-) and monochloramine could promote the transformation of IPM by ZVI, while SiO3(2-) inhibited the transformation of IPM...
November 14, 2017: Water Research
https://www.readbyqxmd.com/read/29160953/assessing-hypervalency-in-iodanes
#2
Andras Stirling
The so-called hypervalent iodane compounds are very useful and versatile reactants and oxidizing agents in modern organic chemistry. The hypercoordinated central iodine in these compounds hints hypervalent state which is often stressed to justify their reactivity. In this study a theoretical analysis of the electronic structure of a large, representative set of hypercoordinated iodane compounds has been done. We obtained that the iodonium is not hypervalent in these compounds. In contrast, the analysis reveals a variation of the iodine valence state from normal octet state to hypovalent depending on the ligands, but irrespective of the coordination number...
November 21, 2017: Chemistry: a European Journal
https://www.readbyqxmd.com/read/29155635/case-248-cystic-duodenal-dystrophy-with-groove-pancreatitis
#3
Aruna R Patil, Shrivalli Nandikoor, Govindarajan Mallarajapatna, Swarna Shivakumar
History A 59-year-old man presented to the gastroenterology outpatient department with acute abdominal pain centered in the epigastrium. He had experienced similar episodes of abdominal pain in the past that had been treated with surgery. He reported multiple failed attempts at upper gastrointestinal endoscopy. Laboratory tests were performed at the time of admission and revealed a serum glutamic-oxaloacetic transaminase level of 9 U/L [0.15 μkat/L] (normal range, 5-40 U/L [0.08-0.67 μkat/L]), a serum glutamic-pyruvic transaminase level of 34 U/L [0...
December 2017: Radiology
https://www.readbyqxmd.com/read/29155625/effect-of-iodine-based-contrast-material-on-radiation-dose-at-ct
#4
Ehsan Abadi, Pooyan Sahbaee, Ehsan Samei
No abstract text is available yet for this article.
December 2017: Radiology
https://www.readbyqxmd.com/read/29153359/multi-detector-ct-liver-protocol-and-recent-developments
#5
REVIEW
N Kartalis, K Brehmer, L Loizou
Multi-detector computed tomography is today the workhorse in the evaluation of the vast majority of patients with known or suspected liver disease. Reasons for that include widespread availability, robustness and repeatability of the technique, time-efficient image acquisitions of large body volumes, high temporal and spatial resolution as well as multiple post-processing capabilities. However, as the technique employs ionizing radiation and intravenous iodine-based contrast media, the associated potential risks have to be taken into account...
December 2017: European Journal of Radiology
https://www.readbyqxmd.com/read/29153027/annals-express-large-abnormal-peak-on-capillary-zone-electrophoresis-due-to-contrast-agent
#6
Rachel D Wheeler, Liqun Zhang, Joanna Sheldon
BACKGROUND: Some iodinated radio-contrast media absorb UV light and can therefore be detected by capillary zone electrophoresis (CZE). If seen, these peaks are typically small with "quantifications" of below 5g/L. Here we describe detection of a large peak on CZE that was due to the radio-contrast agent, Omnipaque(T)(M). METHODS: Serum from a patient was analysed by CZE, and the IgG, IgA, IgM and total protein concentrations were measured. The serum sample was further analysed by gel electrophoresis and immunofixation...
January 1, 2017: Annals of Clinical Biochemistry
https://www.readbyqxmd.com/read/29138890/role-of-rapid-kv-switching-dual-energy-ct-in-assessment-of-post-surgical-local-recurrence-of-pancreatic-adenocarcinoma
#7
Anushri Parakh, Manuel Patino, Daniela Muenzel, Avinash Kambadakone, Dushyant V Sahani
PURPOSE: The purpose of this study is to evaluate the performance of material-specific iodine (MS-I) images generated by rapid kV-switching single-source dual-energy computed tomography (rsDECT) for distinguishing post-operative changes from local tumor recurrence in patients on follow-up for pancreatic adenocarcinoma after surgical resection. METHODS: In this IRB-approved HIPPA-compliant study, retrospective review of 51 patients who underwent surgical resection of pancreatic adenocarcinoma was conducted and were followed up using contrast-enhanced rsDECT (Discovery CT 750HD, GE Healthcare, Milwaukee, WI)...
November 14, 2017: Abdominal Radiology
https://www.readbyqxmd.com/read/29137904/implications-of-iodinated-contrast-media-extravasation-in-the-emergency-department
#8
Jonathan D Sonis, Ravi V Gottumukkala, McKinley Glover, Brian J Yun, Benjamin A White, Mannudeep K Kalra, Alexi Otrakji, Ali S Raja, Anand M Prabhakar
PURPOSE: To characterize the management, outcomes, and emergency department (ED) length of stay (LOS) following iodinated contrast media extravasation events in the ED. METHODS: All ED patients who developed iodinated contrast media extravasation following contrast-enhanced CT (CECT) from October 2007-December 2016 were retrospectively identified. Medical records were reviewed and management, complications, frequency of surgical consultation, and ED LOS were quantified using descriptive statistics...
November 7, 2017: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29134367/imaging-of-cardiovascular-disease-in-pregnancy-and-the-peripartum-period
#9
REVIEW
Theodore Pierce, Meline Hovnanian, Sandeep Hedgire, Brian Ghoshhajra
Cardiovascular disease is an important cause of morbidity and mortality during pregnancy and the postpartum period. During pregnancy, the cardiovascular system undergoes extensive hemodynamic, hormonal, and microstructural changes which may exacerbate a preexisting underlying cardiovascular condition or predispose to cardiovascular complications not typically seen in young healthy women. Such conditions include spontaneous coronary artery dissection, atherosclerotic coronary artery disease, and peripartum cardiomyopathy...
November 14, 2017: Current Treatment Options in Cardiovascular Medicine
https://www.readbyqxmd.com/read/29131773/update-on-cardiovascular-applications-of-multienergy-ct
#10
Kevin Kalisz, Sandra Halliburton, Suhny Abbara, Jonathon A Leipsic, Moritz H Albrecht, U Joseph Schoepf, Prabhakar Rajiah
Advances in scanner technology enabling shorter scan times, improvements in spatial and temporal resolution, and more dose-efficient data reconstruction coupled with rapidly growing evidence from clinical trials have established computed tomography (CT) as an important imaging modality in the evaluation of cardiovascular disorders. Multienergy (or spectral or dual-energy) CT is a relatively recent advance in which attenuation data from different energies are used to characterize materials beyond what is possible at conventional CT...
November 2017: Radiographics: a Review Publication of the Radiological Society of North America, Inc
https://www.readbyqxmd.com/read/29129788/a-new-formulation-of-poly-maotib-nanoparticles-as-an-efficient-contrast-agent-for-in-vivo-x-ray-imaging
#11
Justine Wallyn, Nicolas Anton, Christophe Serra, Michel Bouquey, Mayeul Collot, Halina Anton, Jean-Luc Weickert, Nadia Messaddeq, Thierry F Vandamme
Polymeric nanoparticles (PNPs) are gaining increasing importance as nanocarriers or contrasting material for preclinical diagnosis by micro-CT scanner. Here, we investigated a straightforward approach to produce a biocompatible, radiopaque, and stable polymer-based nanoparticle contrast agent, which was evaluated on mice. To this end, we used a nanoprecipitation dropping technique to obtain PEGylated PNPs from a preformed iodinated homopolymer, poly(MAOTIB), synthesized by radical polymerization of 2-methacryloyloxyethyl(2,3,5-triiodobenzoate) monomer (MAOTIB)...
November 9, 2017: Acta Biomaterialia
https://www.readbyqxmd.com/read/29123502/anaplastic-thyroid-cancer-in-sicily-the-role-of-environmental-characteristics
#12
Martina Tavarelli, Pasqualino Malandrino, Paolo Vigneri, Pierina Richiusa, Adele Maniglia, Maria A Violi, Giulia Sapuppo, Veronica Vella, Gabriella Dardanoni, Riccardo Vigneri, Gabriella Pellegriti
Background: Anaplastic thyroid cancer (ATC) is a rare but extremely aggressive cancer of the thyroid, contributing up to 30-40% of thyroid cancer-specific mortality. We analyzed ATC characteristics and survival rates in Sicily to evaluate the possible influence of environmental factors. With this aim, data regarding ATC incidences in urban/rural and industrial, iodine-deficient, and volcanic vs control areas were compared in Sicily as well as ATC data from Sicily and USA. Methods: Using the Sicilian Register of Thyroid Cancer (SRTC) database incidence, age, gender, tumor size and histotype, extrathyroidal extension, stage, and coexistence with pre-existing differentiated thyroid cancer (DTC) were evaluated in different areas of Sicily and also compared with Surveillance Epidemiology and End Results data in USA...
2017: Frontiers in Endocrinology
https://www.readbyqxmd.com/read/29119457/dual-energy-computed-tomography-for-the-head
#13
REVIEW
Norihito Naruto, Toshihide Itoh, Kyo Noguchi
Dual energy CT (DECT) is a promising technology that provides better diagnostic accuracy in several brain diseases. DECT can generate various types of CT images from a single acquisition data set at high kV and low kV based on material decomposition algorithms. The two-material decomposition algorithm can separate bone/calcification from iodine accurately. The three-material decomposition algorithm can generate a virtual non-contrast image, which helps to identify conditions such as brain hemorrhage. A virtual monochromatic image has the potential to eliminate metal artifacts by reducing beam-hardening effects...
November 9, 2017: Japanese Journal of Radiology
https://www.readbyqxmd.com/read/29119033/the-utility-of-mri-in-the-diagnosis-of-takayasu-arteritis
#14
Marian Gaballah, Rachelle Goldfisher, John B Amodio
Takayasu Arteritis (TA) is an inflammatory disorder involving the thoracoabdominal aorta and its branches and the pulmonary arteries, with eventual vascular stenosis, occlusion, or aneurysm formation. Conventional angiography has been the reference imaging standard for diagnosis of TA. The purpose of this case report is to demonstrate the utility of MR imaging and MR angiography in the diagnosis of Takayasu Arteritis in a pediatric patient. The patient is a 15-year-old female patient presenting with anemia, hypertension, and acute kidney injury...
2017: Case Reports in Pediatrics
https://www.readbyqxmd.com/read/29117707/susceptibility-of-iodine-concentration-map-of-dual-energy-contrast-enhanced-digital-mammography-for-quantitative-and-tumor-enhancement-assessment
#15
Yi-Shuan Hwang, Yun-Chung Cheung, Yu-Ying Lin, Hsiao-Lan Hsu, Hui-Yu Tsai
Background Dual-energy (DE) contrast-enhanced digital mammography (DE-CEDM) provides additional information on tumor angiogenesis. Purpose To investigate the susceptibility of reconstructing color-coded iodine concentration maps on the basis of quantitative calibrations of the iodine concentration and contrast-to-noise ratio (CNR) in DE-CEDM applications. Material and Methods A custom-made phantom filled with iodine concentrations in the range of 0.1-10 mg/cm(2) was used in calibrations. All DE images were acquired using the GE Senographe Essential system...
January 1, 2017: Acta Radiologica
https://www.readbyqxmd.com/read/29112977/initial-clinical-experience-with-dual-layer-detector-spectral-ct-in-patients-with-acute-intracerebral-haemorrhage-a-single-centre-pilot-study
#16
Soo Buem Cho, Hye Jin Baek, Kyeong Hwa Ryu, Jin Il Moon, Bo Hwa Choi, Sung Eun Park, Kyungsoo Bae, Kyung Nyeo Jeon, Dong Wook Kim
PURPOSE: The purpose of this study was to investigate the clinical feasibility of spectral analyses using dual-layer detector spectral computed tomography (CT) in acute intracerebral haemorrhage (ICH). MATERIAL AND METHODS: We retrospectively reviewed patients with acute ICH who underwent CT angiography on a dual-layer detector spectral CT scanner. A spectral data analysis was performed to detect contrast enhancement in or adjacent to acute ICH by using spectral image reconstructions including monoenergetic (MonoE), virtual noncontrast (VNC), and iodine overlay fusion images...
2017: PloS One
https://www.readbyqxmd.com/read/29108806/cerebral-infarcts-by-nonbacterial-thrombotic-endocarditis-associated-with-adenomyosis-a-case-report
#17
Byungseok Kim, Seong-Hoon Kim, Taewon Kim
We report a case of multiple embolic cerebral infarcts associated with nonbacterial thrombotic endocarditis (NBTE) in a patient with adenomyosis. The patient presented with dysarthria, left perioral sensory change, and left-hand weakness. Magnetic resonance imaging revealed multiple vascular territory infarctions involving the bilateral cerebellum and the right precentral gyrus. Magnetic resonance angiography was normal. d-Dimer, carbohydrate antigen (CA) 19-9, and CA125 levels were elevated. Abdominal and pelvic computed tomography with iodine contrast enhancement revealed a huge adenomyosis with left ovarian cyst...
November 3, 2017: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/29104815/a-novel-nano-approach-for-targeted-inner-ear-imaging
#18
M N Kayyali, L Brake, A J Ramsey, A C Wright, B W O'Malley, D Daqing Li
During the last decade, there have been major improvements in imaging modalities and the development of molecular imaging in general. However detailed inner ear imaging still provides very limited information to physicians. This is unsatisfactory as sensorineural hearing loss is the main cause of permanent hearing loss in adults and at least 134 genetic mutations that result in congenital hearing loss have been identified. We are still unable, in most cases where gross anatomical changes are not observed, to determine the exact cause of hearing loss at a cellular or molecular level in patients using non-invasive techniques...
August 2017: Journal of Nanomedicine & Nanotechnology
https://www.readbyqxmd.com/read/29103468/correlations-between-the-iodine-concentrations-from-dual-energy-computed-tomography-and-molecular-markers-ki-67-and-hif-1%C3%AE-in-rectal-cancer-a-preliminary-study
#19
Shuxuan Fan, Xubin Li, Lei Zheng, Dongzhi Hu, Xiaoyi Ren, Zhaoxiang Ye
PURPOSE: To investigate whether dual energy computed tomography (CT) with iodine quantification is correlated with molecular markers Ki-67and hypoxia-inducible factor 1α (HIF-1α)in rectal cancer (RC). MATERIALS AND METHODS: Eighty patients (43 males and 37 females) diagnosed with rectal cancer got pelvic contrast-enhanced CT scan with dual energy computed tomography before any anticancer treatment. Analyse the normalized iodine concentration (NIC) values and CT values at each energy level (40-140 keV) from the virtual monochromatic image of the primary lesions...
November 2017: European Journal of Radiology
https://www.readbyqxmd.com/read/29102859/three-dimensional-mammalian-tooth-development-using-dicect
#20
Qamariya Nasrullah, Marilyn B Renfree, Alistair R Evans
OBJECTIVE: This study aims to develop the Diffusible Iodine-based Contrast-Enhanced CT (diceCT) method for non-destructive imaging of both soft and mineralised tissues. We sought to document the 3D spatio-temporal pattern of mammalian tooth development including multiple tooth classes and generations, using the tammar wallaby (Macropus eugenii) as a model species. DESIGN: We took microCT scans of developing fetuses and pouch young stained using Lugol's Iodine (I2KI) contrast agent...
October 20, 2017: Archives of Oral Biology
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