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neutrophil lymphocyte ratio (NLR)

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https://www.readbyqxmd.com/read/28636535/the-correlation-of-neutrophil-to-lymphocyte-ratio-with-the-presence-and-activity-of-myasthenia-gravis
#1
De-Hao Yang, Mei-Zi Qian, Mao-Mao Wei, Jia Li, Meng-Meng Yu, Xue-Mian Lu, Hong Yang, Hai Lin, Xiang Li, Jun-Yan Zhu, Xu Zhang
Though the pathogenesis of myasthenia gravis (MG) is not fully understood, the role of inflammation has been well appreciated in the development of MG. We aimed to investigate the role of neutrophil-to-lymphocyte ratio (NLR) in MG patients and the relationship between the NLR and the activity of the disease. A total number of 172 MG patients and 207 healthy controls (HC) were enrolled in this study. The MG patients were divided into tertiles according to NLR (low NLR < 1.58, n = 57; intermediate NLR 1.58-2...
June 16, 2017: Oncotarget
https://www.readbyqxmd.com/read/28635513/evaluation-of-platelet-indices-and-red-cell-distribution-width-as-new-biomarkers-for-the-diagnosis-of-acute-appendicitis
#2
Noha Boshnak, Mohamed Boshnaq, Hatem Elgohary
BACKGROUND: Debate around the value of laboratory tests in establishing the diagnosis of acute appendicitis (AA) still continues. This prospective study aimed to investigate the changes in mean platelet volume (MPV), platelet distribution width (PDW), and red cell distribution width (RDW) with the diagnosis of acute appendicitis. METHOD: 200 patients who underwent emergency appendectomy were included. According to postoperative histology, patients were divided into three groups: acute non-complicated, acute complicated appendicitis (positive appendicectomy groups), and negative appendectomy group...
February 16, 2017: Journal of Investigative Surgery: the Official Journal of the Academy of Surgical Research
https://www.readbyqxmd.com/read/28635304/the-relationship-between-the-neutrophil-lymphocyte-ratio-and-in-stent-restenosis-in-patients-with-femoropopliteal-chronic-total-occlusions
#3
Zhihui Chang, Jiahe Zheng, Zhaoyu Liu, Qiyong Guo
We investigated the relationship between the neutrophil-lymphocyte ratio (NLR) and in-stent restenosis (ISR) in patients with femoropopliteal chronic total occlusions (CTOs). The study enrolled 180 patients who had undergone successful stenting treatment for femoropopliteal CTO. Patients with ISR were subsequently classified into 2 groups: early-ISR (within 1 year) and late-ISR (after 1 year). The clinical characteristics, angiographic data, and follow-up data were recorded. The baseline NLR was significantly higher in the early-ISR group than that in the non-ISR group [3...
January 1, 2017: Angiology
https://www.readbyqxmd.com/read/28634671/venous-thromboembolism-is-an-independent-predictor-of-mortality-among-patients-with-gastric-cancer
#4
Harry E Fuentes, D M Oramas, L H Paz, Y Wang, X A Andrade, A J Tafur
BACKGROUND: Venous thromboembolism (VTE) is an independent predictor of death among patients with cancer. Patients with gastric cancer (GC) are at higher risk for VTE when compared to other solid tumors, and if one considers its prevalence, GC may be responsible for one of the highest incidences of cancer-associated thrombosis. The impact of VTE on mortality is not well defined among patients with GC. AIM: The aim of this study is to measure the impact of VTE as independent predictor of GC mortality...
June 21, 2017: Journal of Gastrointestinal Cancer
https://www.readbyqxmd.com/read/28625236/-eosinophil-could-predict-the-prognosis-of-patients-with-bloodstream-infection-a-retrospective-analysis-of-305-cases
#5
Duan Guo, Chao Jia, Hang Su
OBJECTIVE: To investigate the value of peripheral blood for the prognosis of patients with bloodstream infection. METHODS: A retrospective analysis of patients with bloodstream infection was conducted in the intensive care unit (ICU) of Mianyang Central Hospital of Sichuan from January 2012 to October 2016. According to the 28-day survival, the patients were divided into survival group and death group. The white blood cell (WBC), neutrophils count (NEU), lymphocyte count (LYM), neutrophil/lymphocyte ratio (NLR), monocyte count (MO), eosinophil count (EO), basophil count (BA), hemoglobin (Hb), platelet count (PLT) and procalcitonin (PCT) in peripheral blood were recorded when patients were diagnosed with blood infection...
June 2017: Zhonghua Wei Zhong Bing Ji Jiu Yi Xue
https://www.readbyqxmd.com/read/28623016/the-relationship-between-neutrophil-to-lymphocyte-ratio-and-fragmented-qrs-in-acute-stemi-patients-treated-with-primary-pci
#6
Zulkif Tanriverdi, Tugce Colluoglu, Huseyin Dursun, Dayimi Kaya
BACKGROUND: No study so far investigated fragmented QRS (fQRS) and neutrophil-to-lymphocyte ratio (NLR) together in ST segment elevation myocardial infarction (STEMI). OBJECTIVE: To investigate the relationship between NLR and fQRS, and determine the prognostic significance of the combined use of these two parameters in STEMI. METHODS: We included 368 patients with first acute STEMI who successfully revascularized with primary percutaneous coronary intervention...
June 8, 2017: Journal of Electrocardiology
https://www.readbyqxmd.com/read/28621246/association-between-admission-neutrophil-to-lymphocyte-ratio-and-outcomes-in-patients-with-acute-exacerbation-of-chronic-obstructive-pulmonary-disease
#7
Shaghayegh Rahimirad, Mohammad Reza Ghaffary, Mohammad Hossein Rahimirad, Farid Rashidi
Introduction: The prognostic significance of neutrophil-to-lymphocyte ratio (NLR), derived-neutrophil-to-lymphocyte ratio (d-NLR), platelet-to-lymphocyte ratio (PLR), and lymphocyte-to-monocyte ratio (LMR) have been shown in many diseases. To the best of our knowledge, there is no published report evaluation of those parameters in acute exacerbation of chronic obstructive pulmonary disease (AECOPD). The aims of this study are to evaluate the parameters in predicting in-hospital mortality in patients with AECOPD...
March 2017: Tüberküloz Ve Toraks
https://www.readbyqxmd.com/read/28618180/neutrophil-lymphocyte-ratio-and-a-dosimetric-factor-for-predicting-symptomatic-radiation-pneumonitis-in-non-small-cell-lung-cancer-patients-treated-with-concurrent-chemoradiotherapy
#8
Yun Hee Lee, Hoon-Sik Choi, Hojin Jeong, Ki Mun Kang, Jin Ho Song, Won Sup Lee, Gyeong-Won Lee, Haa-Na Song, Hoon-Gu Kim, Myoung Hee Kang, Dong Yoon Rhee, Bae Kwon Jeong
OBJECTIVES: To identify the factors that predict the progression of radiological radiation pneumonitis (RP) to symptomatic RP, and to evaluate the usefulness of the neutrophil-lymphocyte ratio (NLR) as a marker of RP severity and prognosis in stage III non-small cell lung cancer (NSCLC) patients treated with definitive concurrent chemoradiotherapy (CCRT). MATERIALS AND METHODS: We retrospectively reviewed 61 patients treated between January 2010 and December 2015...
June 15, 2017: Clinical Respiratory Journal
https://www.readbyqxmd.com/read/28612596/prognostic-value-of-the-neutrophil-to-lymphocyte-ratio-nlr-in-lung-cancer-cases
#9
Berna Akinci Ozyurek, Tugce Sahin Ozdemirel, Sertac Buyukyaylaci Ozden, Yurdanur Erdogan, Bekir Kaplan, Tugba Kaplan
Haemogram assessment is a cheap and easy method which can be readily performed for almost all patients. Leucocyte, neutrophil and lymphocyte counts and the neutrophil to lymphocyte ratio (NLR) are markers of systemic inflammation. We here aimed to evaluate haemogram parameters of our patients with lung cancer according to the pathologic diagnosis of small cell lung cancer (SCLC) and non-small cell lung cancer (NSCLC). Materials and Methods: The study included 386 patients diagnosed with lung cancer in our hospital between January 2006 and January 2014...
May 1, 2017: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/28612534/-associations-of-preoperative-platelet-to-lymphocyte-ratio-and-derived-neutrophil-to-lymphocyte-ratio-with-theprognosis-of-gastrointestinal-stromal-tumor
#10
Xiao-Nan Yin, Su-Min Tang, Yuan Yin, Chao-Yong Shen, Bo Zhang, Zhi-Xin Chen
OBJECTIVES: To determine the associations of preoperative platelet-to-lymphocyte ratio (PLR) and derived neutrophil-to-lymphocyte ratio (d-NLR) with the prognosis of gastrointestinal stromal tumor (GIST). METHODS: GIST patients with surgical treatment from June 2005 to February 2015 in West China Hospital of Sichuan University were enrolled in the study. The results of blood routine tests of the patients within one week prior to surgery and their clinical data were extracted...
March 2017: Sichuan da Xue Xue Bao. Yi Xue Ban, Journal of Sichuan University. Medical Science Edition
https://www.readbyqxmd.com/read/28608032/the-significance-of-neutrophil-to-lymphocyte-ratio-in-idiopathic-epiretinal-membrane
#11
Funda Dikkaya, Sevil Karaman Erdur, Mustafa Ozsutcu, Rukiye Aydin, Mehmet Selim Kocabora, Cengiz Aras
PURPOSE: To assess the levels of neutrophil-to-lymphocyte ratio (NLR) in patients with idiopathic epiretinal membrane (iERM) and to compare the NLR results of patients with iERM and healthy controls. METHODS: This retrospective study enrolled 43 patients with iERM and 40 healthy subjects. Complete ophthalmologic examination and complete blood count measurements were performed of all subjects. Complete blood counts were performed within 2 h of blood collection. RESULTS: There was a significant difference in NLR between iERM and control groups (p < 0...
June 12, 2017: International Ophthalmology
https://www.readbyqxmd.com/read/28607596/elevated-preoperative-neutrophil-to-lymphocyte-ratio-can-predict-poor-survival-in-early-stage-gastric-cancer-patients-receiving-radical-gastrectomy-the-fujian-prospective-investigation-of-cancer-fiesta-study
#12
Dan Hu, Hejun Zhang, Xiandong Lin, Gang Chen, Chao Li, Binying Liang, Yan Chen, Zhaolei Cui, Feng Peng, Xiongwei Zheng, Wenquan Niu
Aims: This cohort study was conducted to evaluate the prognostic impact of blood-routine parameters before radical gastrectomy on gastric cancer mortality. Methods: Total 3012 patients with gastric cancer were consecutively enrolled from a mono-center between 2000 and 2010, and the latest follow-up was completed in 2015. Results: The median follow-up time was 44.05 months. Finally, 1331 out of 3012 gastric cancer patients died from gastric cancer. Per standard deviation increment in neutrophil (hazard ratio or HR=1...
2017: Journal of Cancer
https://www.readbyqxmd.com/read/28606735/neutrophil-to-lymphocyte-ratio-in-castration-resistant-prostate-cancer-patients-treated-with-daily-oral-corticosteroids
#13
Niven Mehra, Adam Sharp, David Lorente, David Dolling, Semini Sumanasuriya, Bernadette Johnson, David Dearnaley, Chris Parker, Johann de Bono
BACKGROUND: The neutrophil to lymphocyte ratio (NLR) has been shown to be highly prognostic across many tumor types, and predictive of treatment outcome in advanced prostate cancer, and has been postulated to be an indirect measure of tumor inflammation. We evaluated the effect of low-dose steroids on NLR in men suffering from castration-resistant prostate cancer (CRPC). PATIENTS AND METHODS: The NLR was evaluated in a prospective randomized phase II trial that compared prednisolone 5 mg twice daily and dexamethasone 0...
May 10, 2017: Clinical Genitourinary Cancer
https://www.readbyqxmd.com/read/28605139/clinical-implications-of-pretreatment-inflammatory-biomarkers-as-independent-prognostic-indicators-in-prostate-cancer
#14
Zhaohui Sun, Ying Ju, Fuyan Han, Xiya Sun, Fang Wang
OBJECTIVES: Research on the relationship between inflammatory biomarkers and malignant tumors has become a hotspot. Many studies have demonstrated that neutrophil-lymphocyte ratio (NLR), platelet-lymphocyte ratio (PLR), and red blood cell distribution width (RDW) could act as independent prognostic indicators for several solid tumors. This study aimed to evaluate the clinical implications of pretreatment inflammatory biomarkers, including NLR, PLR, and RDW as independent prognostic indicators in prostate cancer (PCa)...
June 12, 2017: Journal of Clinical Laboratory Analysis
https://www.readbyqxmd.com/read/28603425/pretreatment-combination-of-platelet-counts-and-neutrophil-lymphocyte-ratio-predicts-survival-of-nasopharyngeal-cancer-patients-receiving-intensity-modulated-radiotherapy
#15
Yu-Hsuan Lin, Kuo-Ping Chang, Yaoh-Shiang Lin, Ting-Shou Chang
BACKGROUND: Increased cancer-related inflammation has been associated with unfavorable clinical outcomes. The combination of platelet count and neutrophil-lymphocyte ratio (COP-NLR) has related outcomes in several cancers, except for nasopharyngeal carcinoma (NPC). This study evaluated the prognostic value of COP-NLR in predicting outcome in NPC patients treated with intensity-modulated radiotherapy (IMRT). MATERIALS AND METHODS: We analyzed the data collected from 232 NPC patients...
2017: OncoTargets and Therapy
https://www.readbyqxmd.com/read/28602879/prognostic-role-of-pretreatment-blood-neutrophil-to-lymphocyte-ratio-in-advanced-cancer-survivors-a-systematic-review-and-meta-analysis-of-66-cohort-studies
#16
REVIEW
Zubing Mei, Lu Shi, Bo Wang, Jizhen Yang, Zhihong Xiao, Peixin Du, Qingming Wang, Wei Yang
BACKGROUND: Neutrophil-to-lymphocyte ratio (NLR) is crucial for the incidence and mortality of various tumors. However, little is known on NLR and its association with prognosis in advanced tumors. Here we performed a meta-analysis to establish the prognostic significance of pretreatment blood NLR for advanced tumors. METHODS: A systematic literature search through April 2016 was performed to evaluate the association between pretreatment blood NLR and overall survival (OS) or progression-free survival (PFS) in patients with advanced tumors...
May 29, 2017: Cancer Treatment Reviews
https://www.readbyqxmd.com/read/28602056/declined-preoperative-aspartate-aminotransferase-to-neutrophil-ratio-index-predicts-poor-prognosis-in-patients-with-intrahepatic-cholangiocarcinoma-after-hepatectomy
#17
Lingyun Liu, Wei Wang, Yi Zhang, Jianting Long, Zhaohui Zhang, Qiao Li, Bin Chen, Shaoqiang Li, Yunpeng Hua, Shunli Shen, Baogang Peng
Purpose: Various inflammation-based prognostic biomarkers such as the platelet to lymphocyte ratio and neutrophil to lymphocyte ratio (NLR), are related to poor survival in patients with intrahepatic cholangiocarcinoma (ICC). This study aims to investigate the prognostic value of the aspartate aminotransferase to neutrophil ratio index (ANRI) in ICC after hepatic resection. Materials and Methods: Data of 184 patients with ICC after hepatectomy were retrospectively reviewed...
June 1, 2017: Cancer Research and Treatment: Official Journal of Korean Cancer Association
https://www.readbyqxmd.com/read/28601234/comparison-of-echocardiographic-findings-in-patients-with-nonfunctioning-adrenal-incidentalomas
#18
Narin Nasıroglu Imga, Ozgul Ucar Elalmıs, Mazhar Muslum Tuna, Bercem Aycıcek Dogan, Deniz Sahın, Tugba Gursoy, Yavuz Yalcın, Dilek Berker, Serdar Guler
Adrenal incidentalomas (AIs) are usually discovered incidentally after imaging unrelated to adrenal glands. We aimed to evaluate standard risk factors for systemic atherosclerosis and echocardiographic changes in patients with nonfunctioning AIs and compare them with normal subjects. We evaluated 70 patients diagnosed with AIs and 51 healthy controls. Mean levels were determined for HbA1c, LDL, uric acid, fasting plasma insulin, HOMA, and neutrophil-to-lymphocyte ratio (NLR), and these values were found to be significantly higher in the patients than the controls...
June 2017: Kaohsiung Journal of Medical Sciences
https://www.readbyqxmd.com/read/28600686/a-critical-prognostic-analysis-of-neutrophil-lymphocyte-ratio-for-patients-undergoing-nephroureterectomy-due-to-upper-urinary-tract-urothelial-carcinoma
#19
Mesut Altan, Hakan Bahadır Haberal, Bülent Akdoğan, Haluk Özen
BACKGROUND: To determine preoperative serum complete blood count parameters that affects survival of patients who underwent surgery for upper urinary tract urothelial cancer (UUT-UC). METHODS: Since 1990, 150 patients underwent nephroureterectomy with bladder cuff excision for UUT-UC at Hacettepe University. Patients with a history of muscle-invasive bladder cancer, adjuvant chemotherapy or metastasis at the time of diagnosis were excluded. One hundred and thirteen patients without infective symptoms and with a full set of serum data were evaluated retrospectively...
June 9, 2017: International Journal of Clinical Oncology
https://www.readbyqxmd.com/read/28599056/retrospective-study-of-the-prognostic-significance-of-neutrophil-to-lymphocyte-ratio-for-postsurgical-outcomes-of-patients-with-endometrial-carcinoma
#20
Ling Ding, Yi Ding, Xiao-Hua Mao, Jian-Fei Zhao, Huai-Jun Zhou
OBJECTIVE: To evaluate the significance of postoperative inflammatory system response markers in predicting the prognosis of patients with endometrial cancer undergoing surgery. METHODS: The present retrospective study included patients who underwent surgical treatment for pathology-confirmed endometrial cancer between January 1, 2007, and June 30, 2013, at the Affiliated Drum Tower Hospital, Nanjing University Medical School, Nanjing, China. Potential prognostic factors were investigated by Cox proportional hazards analysis and survival rates were compared using Kaplan-Meier analyses...
June 9, 2017: International Journal of Gynaecology and Obstetrics
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