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https://www.readbyqxmd.com/read/28324904/quantifying-neonatal-sucking-performance-promise-of-new-methods
#1
Gilson J Capilouto, Tommy J Cunningham, David R Mullineaux, Eleonora Tamilia, Christos Papadelis, Peter J Giannone
Neonatal feeding has been traditionally understudied so guidelines and evidence-based support for common feeding practices are limited. A major contributing factor to the paucity of evidence-based practice in this area has been the lack of simple-to-use, low-cost tools for monitoring sucking performance. We describe new methods for quantifying neonatal sucking performance that hold significant clinical and research promise. We present early results from an ongoing study investigating neonatal sucking as a marker of risk for adverse neurodevelopmental outcomes...
April 2017: Seminars in Speech and Language
https://www.readbyqxmd.com/read/28324610/designing-image-analysis-pipelines-in-light-microscopy-a-rational-approach
#2
Ignacio Arganda-Carreras, Philippe Andrey
With the progress of microscopy techniques and the rapidly growing amounts of acquired imaging data, there is an increased need for automated image processing and analysis solutions in biological studies. Each new application requires the design of a specific image analysis pipeline, by assembling a series of image processing operations. Many commercial or free bioimage analysis software are now available and several textbooks and reviews have presented the mathematical and computational fundamentals of image processing and analysis...
2017: Methods in Molecular Biology
https://www.readbyqxmd.com/read/28319753/the-impact-of-cannabis-and-cannabinoids-for-medical-conditions-on-health-related-quality-of-life-a-systematic-review-and-meta-analysis
#3
REVIEW
Matthew Goldenberg, Mark William Reid, Waguih William IsHak, Itai Danovitch
INTRODUCTION: The use of cannabis or cannabinoids to treat medical conditions and/or alleviate symptoms is increasingly common. However, the impact of this use on patient reported outcomes, such as health-related quality of life (HRQoL), remains unclear. METHODS: We conducted a systematic review and meta-analysis, employing guidelines from Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). We categorized studies based on design, targeted disease condition, and type of cannabis or cannabinoid used...
March 1, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/28319296/joint-effects-of-climate-variability-and-socio-ecological-factors-on-dengue-transmission-epidemiological-evidence
#4
REVIEW
Rokeya Akter, Wenbiao Hu, Suchithra Naish, Shahera Banu, Shilu Tong
OBJECTIVE: To assess the epidemiological evidence on the joint effects of climate variability and socio-ecological factors on dengue transmission. METHODS: Following PRISMA guidelines, a detailed literature search was conducted in PubMed, Web of Science and Scopus. Peer-reviewed, freely available and full text articles, considering both climate and socio-ecological factors in relation to dengue, published in English from January 1993 to October 2015 were included in this review...
March 20, 2017: Tropical Medicine & International Health: TM & IH
https://www.readbyqxmd.com/read/28319201/recommendations-for-patient-engagement-in-guideline-development-panels-a-qualitative-focus-group-study-of-guideline-na%C3%A3-ve-patients
#5
Melissa J Armstrong, C Daniel Mullins, Gary S Gronseth, Anna R Gagliardi
BACKGROUND: Patient and consumer engagement in clinical practice guideline development is internationally advocated, but limited research explores mechanisms for successful engagement. OBJECTIVE: To investigate the perspectives of potential patient/consumer guideline representatives on topics pertaining to engagement including guideline development group composition and barriers to and facilitators of engagement. SETTING AND PARTICIPANTS: Participants were guideline-naïve volunteers for programs designed to link community members to academic research with diverse ages, gender, race, and degrees of experience interacting with health care professionals...
2017: PloS One
https://www.readbyqxmd.com/read/28316912/intensity-of-commonly-reported-classroom-based-physical-activity-opportunities-in-public-schools
#6
Timothy K Behrens, Whitney M Holeva, Dick Carpenter, Elizabeth Tucker, Carmen Luna, John Donovan, Julaine Field, Cheryl Kelly
The purpose of this study was to examine the intensity levels of PA opportunities offered in public school classrooms. Schools (N = 101) in school districts (N = 25) reported PA opportunities offered in classrooms using an online data collection tool over a two-year period (2014-2016). Using a randomized sampling technique, 20-30% of teachers in each school were selected each week to report PA in their classroom. These responses resulted in N = 18,210 usable responses. A researcher determined the intensity of PA opportunities using the 2011 Compendium of Physical Activities as a guideline; two additional researchers confirmed the coded categories...
June 2017: Preventive Medicine Reports
https://www.readbyqxmd.com/read/28316140/descriptive-review-of-acute-cholecystitis-japan-taiwan-collaborative-epidemiological-study
#7
Masamichi Yokoe, Tadahiro Takada, Tsann-Long Hwang, Itaru Endo, Kohei Akazawa, Fumihiko Miura, Toshihiko Mayumi, Rintaro Mori, Miin-Fu Chen, Yi-Yin Jan, Chen-Guo Ker, Hsiu-Po Wang, Takao Itoi, Harumi Gomi, Seiki Kiriyama, Hiroki Yamaue, Masaru Miyazaki, Masakazu Yamamoto
BACKGROUND AND AIMS: Since the publication of the Tokyo Guidelines (TG13) for the management of acute cholecystitis (AC), multidirectional studies have been published. However epidemiological research about AC with big data was not projected. The aim of this study was to reveal the actual clinical conditions of AC. METHOD: The study was designed as an international multicenter retrospective study of AC in Japan and Taiwan from 2011 to 2013. The factors investigated comprised data related to demographic, history, physical examinations, laboratory and imaging findings...
March 18, 2017: Journal of Hepato-biliary-pancreatic Sciences
https://www.readbyqxmd.com/read/28315875/systematic-review-of-exocrine-pancreatic-insufficiency-after-gastrectomy-for-cancer
#8
Jennifer Straatman, Jim Wiegel, Nicole van der Wielen, E P Jansma, Miguel A Cuesta, Donald L van der Peet
BACKGROUND: Survival rates after a total gastrectomy with adequate lymphadenectomy are improving, leading to a shift in outcomes of interest from survival to postoperative outcomes and symptoms. In this systematic review, we investigate gastrointestinal symptoms that occur after a gastrectomy in relation to exocrine pancreatic insufficiency and the effect of pancreatic exocrine enzyme supplementation on these symptoms. METHODS: Online databases PubMed, Embase, and Cochrane Library were systematically searched in accordance with the PRISMA guidelines...
March 18, 2017: Digestive Surgery
https://www.readbyqxmd.com/read/28315118/the-reference-intervals-of-hair-trace-element-content-in-hereford-cows-and-heifers-bos-taurus
#9
Sergey A Miroshnikov, Oleg A Zavyalov, Alexey N Frolov, Irina P Bolodurina, Valery V Kalashnikov, Andrei R Grabeklis, Alexey A Tinkov, Anatoly V Skalny
The objective of the present study was to assess hair trace element content in Hereford heifers and cows (Bos taurus) living in South Ural region and calculate the site-specific reference intervals. Hair trace element content in 150 cows and heifers farmed in the Southern Urals of Russia was assessed using inductively coupled plasma mass-spectrometry. Dietary trace element content corresponded to the adequate values as estimated by recommendations of USSR State Agriculture Committee and U.S. National Research Council...
March 17, 2017: Biological Trace Element Research
https://www.readbyqxmd.com/read/28314797/effect-of-2013-acc-aha-blood-cholesterol-guidelines-on-statin-treatment-patterns-and-low-density-lipoprotein-cholesterol-in-atherosclerotic-cardiovascular-disease-patients
#10
Ted Okerson, Jeetvan Patel, Stefan DiMario, Tanya Burton, Jerald Seare, David J Harrison
BACKGROUND: Preceding release of the 2013 American College of Cardiology (ACC)/American Heart Association (AHA) cholesterol guidelines, prescribers aimed for specific low-density lipoprotein cholesterol (LDL-C) goals in patients with atherosclerotic cardiovascular disease (ASCVD). The 2013 guidelines changed this focus to treating patients with appropriate statin intensity given their ASCVD risk. We examined statin use and LDL-C levels before and after the 2013 ACC/AHA guidelines in patients with clinical ASCVD as defined in the guidelines...
March 17, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/28314075/expert-views-on-biological-threat-characterization-for-the-u-s-government-a-delphi-study
#11
Crystal R Watson, Matthew C Watson, Gary Ackerman, Gigi Kwik Gronvall
Biological threat characterization (BTC) involves laboratory research conducted for the purpose of biological defense. BTC research is important for improving biological risk assessment and informing resource prioritization. However, there are also risks involved in BTC work, including potential for escape from the laboratory or the misuse of research results. Using a modified Delphi study to gather opinions from U.S. experts in biosecurity and biodefense, this analysis explores what principles and safeguards can maximize the benefits of BTC research and ensure that it is conducted safely and securely...
March 17, 2017: Risk Analysis: An Official Publication of the Society for Risk Analysis
https://www.readbyqxmd.com/read/28306684/implementation-and-outcomes-of-a-community-based-pulmonary-rehabilitation-program-in-rural-appalachia
#12
Daniel Doyle, Chaffee Tommarello, Mike Broce, Mary Emmett, Cecil Pollard
PURPOSE: To report on the implementation and clinical outcomes of a community-based pulmonary rehabilitation program in rural Appalachia. METHODS: Three rural health centers and a large referral hospital worked together to establish pulmonary rehabilitation services based on AACVPR guidelines. Each site hired at least 1 respiratory therapist. To measure clinical outcomes, a retrospective medical record study compared pre- and post-program values for the modified Medical Research Council dyspnea level, 6-minute walk test (6MWT), negative inspiratory force (NIF), respiratory disease knowledge, St George Respiratory Questionnaire (SGRQ), BODE index (body mass index, airflow obstruction, dyspnea and exercise capacity), and smoking status...
March 16, 2017: Journal of Cardiopulmonary Rehabilitation and Prevention
https://www.readbyqxmd.com/read/28306489/evaluation-for-association-between-urolithiasis-and-chronic-kidney-disease-in-cats
#13
Andréanne Cléroux, Kate Alexander, Guy Beauchamp, Marilyn Dunn
OBJECTIVE To determine whether urolithiasis is associated with chronic kidney disease (CKD) in cats. DESIGN Retrospective case-control study. ANIMALS 126 cats (59 and 67 with and without urolithiasis, respectively). PROCEDURES Medical records from June 2006 to July 2013 were searched to identify cats that underwent abdominal or focal urinary tract ultrasonography and for which serum creatinine concentration and urine specific gravity data were obtained ≤ 14 days before or after the examination. In cats with (urolithiasis group) and without (control group) urolithiasis, the presence of CKD was determined according to International Renal Interest Society guidelines...
April 1, 2017: Journal of the American Veterinary Medical Association
https://www.readbyqxmd.com/read/28306359/spinal-cord-injuries-how-could-cell-therapy-help
#14
Anna Badner, Ahad M Siddiqui, Michael G Fehlings
Spinal cord injury (SCI) is a devastating condition, where regenerative failure and cell loss lead to paralysis. The heterogeneous and time-sensitive pathophysiology has made it difficult to target tissue repair. Despite many medical advances, there are no effective regenerative therapies. As stem cells offer multi-targeted and environmentally responsive benefits, cell therapy is a promising treatment approach. Areas covered: This review highlights the cell therapies being investigated for SCI, including Schwann cells, olfactory ensheathing cells, mensenchymal stem/stromal cells, neural precursors, oligodendrocyte progenitors, embryonic stem cells, and induced pluripotent stem cells...
March 17, 2017: Expert Opinion on Biological Therapy
https://www.readbyqxmd.com/read/28304251/using-hematology-data-from-malaria-vaccine-research-trials-in-humans-and-rhesus-macaques-macaca-mulatta-to-guide-volume-limits-for-blood-withdrawal
#15
Sara R Hegge, Bradley W Hickey, Shannon M Mcgrath, V Ann Stewart
Guidelines on safe volume limits for blood collection from research participants in both humans and laboratory animals vary widely between institutions. The main adverse event that may be encountered in large blood volume withdrawal is iron-deficiency anemia. Monitoring various parameters in a standard blood panel may help to prevent this outcome. To this end, we analyzed the Hgb and MCV values from 43 humans and 46 macaques in malaria vaccine research trials. Although the percentage of blood volume removed was greater for macaques than humans, macaques demonstrated an overall increase of MCV over time, indicating the ability to respond appropriately to frequent volume withdrawals...
December 1, 2016: Comparative Medicine
https://www.readbyqxmd.com/read/28303425/common-data-elements-for-clinical-research-in-mitochondrial-disease-a-national-institute-for-neurological-disorders-and-stroke-project
#16
Amel Karaa, Shamima Rahman, Anne Lombès, Patrick Yu-Wai-Man, Muniza K Sheikh, Sherita Alai-Hansen, Bruce H Cohen, David Dimmock, Lisa Emrick, Marni J Falk, Shana McCormack, David Mirsky, Tony Moore, Sumit Parikh, John Shoffner, Tanja Taivassalo, Mark Tarnopolsky, Ingrid Tein, Joanne C Odenkirchen, Amy Goldstein
OBJECTIVES: The common data elements (CDE) project was developed by the National Institute of Neurological Disorders and Stroke (NINDS) to provide clinical researchers with tools to improve data quality and allow for harmonization of data collected in different research studies. CDEs have been created for several neurological diseases; the aim of this project was to develop CDEs specifically curated for mitochondrial disease (Mito) to enhance clinical research. METHODS: Nine working groups (WGs), composed of international mitochondrial disease experts, provided recommendations for Mito clinical research...
March 16, 2017: Journal of Inherited Metabolic Disease
https://www.readbyqxmd.com/read/28303273/practice-patterns-of-speech-language-pathologists-in-pediatric-vocal-health
#17
Naomi A Hartley, Maia Braden, Susan L Thibeault
Purpose: The purpose of this study was to investigate current practices of speech-language pathologists (SLPs) in the management of pediatric vocal health, with specific analysis of the influence of clinical specialty and workplace setting on management approaches. Method: American Speech-Language-Hearing Association-certified clinicians providing services within the United States (1%-100% voice caseload) completed an anonymous online survey detailing clinician demographics; employment location and service delivery models; approaches to continuing professional development; and specifics of case management, including assessment, treatment, and discharge procedures...
March 16, 2017: American Journal of Speech-language Pathology
https://www.readbyqxmd.com/read/28302739/changing-landscape-of-congenital-heart-disease
#18
Berto J Bouma, Barbara J M Mulder
Congenital heart disease is the most frequently occurring congenital disorder affecting ≈0.8% of live births. Thanks to great efforts and technical improvements, including the development of cardiopulmonary bypass in the 1950s, large-scale repair in these patients became possible, with subsequent dramatic reduction in morbidity and mortality. The ongoing search for progress and the growing understanding of the cardiovascular system and its pathophysiology refined all aspects of care for these patients. As a consequence, survival further increased over the past decades, and a new group of patients, those who survived congenital heart disease into adulthood, emerged...
March 17, 2017: Circulation Research
https://www.readbyqxmd.com/read/28301800/indigenous-peoples-experiences-and-perceptions-of-hospitalisation-for-acute-care-a-metasynthesis-of-qualitative-studies
#19
REVIEW
Vainess Mbuzi, Paul Fulbrook, Melanie Jessup
OBJECTIVE: The objective of this study was to explore Indigenous people's experiences and perceptions of hospitalisation and acute care. METHODS: Systematic procedures were used for the literature search covering the period from 2000 to 2016. Final search was conducted in early September 2016. Quality of the selected studies was assessed using the Critical Appraisal Skills Program. Data extraction was conducted using the data extraction tool from the Joanna Briggs Institute...
March 6, 2017: International Journal of Nursing Studies
https://www.readbyqxmd.com/read/28301616/use-of-biologics-in-private-practice-nine-years-of-lessons-and-learning
#20
Lilia M Correa-Selm, Mahin Alamgir, Babar K Rao
<p>Over a decade ago, the FDA approved biologics for psoriasis, which changed how the disease is treated and, in most cases, has a significant positive impact on the lives of patients. Side effects primarily identified during the investigational and research phase led to the development of specific guidelines for treatment. The treatment guidelines have been amended to incorporate better understandings of side-effects over the years that the disease has been treated. In this study, we focused on a chart review that included assessing the current guidelines and their alignment with modern patient management and the recent side effects presented...
March 1, 2017: Journal of Drugs in Dermatology: JDD
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