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https://www.readbyqxmd.com/read/28223143/comparison-of-photoinactivation-of-t-rubrum-by-new-methylene-blue-nmb-and-indocyanine-green-emundo-%C3%A2
#1
Reza Fekrazad, Arash Poorsattar Bejeh Mir, Mina Kahyaie Aghdam, Vadood Ghasemi Barghi
BACKGROUND: Superficial mycotic skin infections which are predominantly caused by Trichophyton rubrum, poorly responses to conventional therapies. A great amount of attention has focused on to find more effective treatments. The current work is aimed to compare the effectiveness of phoinactivation of Trichophyton rubrum by two relatively new photosensitizers: a phenothiazinium dye(New methylene blue) and Indocyanine green (EmunDo(®)). MATERIALS AND METHODS: A Final inoculum of T...
February 18, 2017: Photodiagnosis and Photodynamic Therapy
https://www.readbyqxmd.com/read/28215890/effect-of-oral-calcium-administration-on-the-cure-and-reproductive-performance-of-holstein-cows-diagnosed-with-puerperal-metritis
#2
Pablo Pinedo, Juan Velez, Gilberto Solano, Nelson Rodriguez, Julianne Naves, Gustavo M Schuenemann, Carlos Risco
Our objective was to evaluate the effect of oral calcium administration on clinical cure, survival, subsequent presentation of peripartal health disorders, and reproductive performance of Holstein cows diagnosed with puerperal metritis (PM) under certified organic management. A second objective was to evaluate the metabolic status at calving and at the time of PM diagnosis (d 0) in affected and matched healthy cows. Cows diagnosed with PM (n = 200) were assigned randomly to receive 1 of 2 treatments: (1) control received 3...
February 16, 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/28215169/bioactive-constituents-from-an-endophytic-fungus-penicillium-polonicum-nfw9-associated-with-taxus-fauna
#3
Nighat Fatima, Tawanun Sripisut, Ui Joung Youn, Safia Ahmed, Ihsan Ul-Haq, Ulyana Muñoz-Acuña, Charles J Simmons, Muneer Ahmed Qazi, Muniba Jadoon, Ghee Teng Tan, Esperanza J Carcache de Blanco, Leng Chee Chang
BACKGROUND: Endophytic fungi are being recognized as vital and untapped sources of a variety of structurally novel and unique bioactive secondary metabolites in the field of natural products drug discovery. Herein, this study reports the isolation and characterization of secondary metabolites from an endophytic fungus Penicillium polonicum (NFW9) associated with Taxus fuana. METHODS: Extracts of the endophytic fungus cultured on potato dextrose agar were purified using several chromatographic techniques...
February 16, 2017: Medicinal Chemistry
https://www.readbyqxmd.com/read/28205208/skin-to-skin-care-for-procedural-pain-in-neonates
#4
REVIEW
Celeste Johnston, Marsha Campbell-Yeo, Timothy Disher, Britney Benoit, Ananda Fernandes, David Streiner, Darlene Inglis, Rebekah Zee
BACKGROUND: Skin-to-skin care (SSC), often referred to as 'kangaroo care' (KC) due to its similarity with marsupial behaviour of ventral maternal-infant contact, is one non-pharmacological intervention for pain control in infants. OBJECTIVES: The primary objectives were to determine the effect of SSC alone on pain from medical or nursing procedures in neonates compared to no intervention, sucrose or other analgesics, or additions to simple SSC such as rocking; and to determine the effects of the amount of SSC (duration in minutes), method of administration (e...
February 16, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28164647/ethylenediaminetetraacetic-acid-sodium-citrate-heparin-and-citrate-phosphate-dextrose-adenine-anticoagulants-differentially-affect-cytokine-mrna-expression-in-blood-leukocytes
#5
Eva Herzogova, Pavlina Dankova
BACKGROUND: The aim of this study is to determine whether and how the anticoagulant agents EDTA, sodium citrate, and heparin present in vacutainers and CPDA located in transfusion bags modify peripheral blood cell behavior. METHODS: We compared the effect of four anticoagulants within an expression study quantifying mRNA by realtime PCR in 60 blood samples. RESULTS: We observed a significant increase of TNFα and CCL2 mRNA expression in leukocytes placed in EDTA anticoagulant compared to leukocytes collected with citrate or heparin (p ≤ 0...
July 1, 2016: Clinical Laboratory
https://www.readbyqxmd.com/read/28141899/intravenous-midazolam-infusion-for-sedation-of-infants-in-the-neonatal-intensive-care-unit
#6
REVIEW
Eugene Ng, Anna Taddio, Arne Ohlsson
BACKGROUND: Proper sedation for neonates undergoing uncomfortable procedures may reduce stress and avoid complications. Midazolam is a short-acting benzodiazepine that is used increasingly in neonatal intensive care units (NICUs). However, its effectiveness as a sedative in neonates has not been systematically evaluated. OBJECTIVES: Primary objeciveTo assess the effectiveness of intravenous midazolam infusion for sedation, as evaluated by behavioural and/or physiological measurements of sedation levels, in critically ill neonates in the NICU...
January 31, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28121797/the-effect-of-postexercise-carbohydrate-and-protein-ingestion-on-bone-metabolism
#7
Rebecca Townsend, Kirsty J Elliott-Sale, Kevin Currell, Jonathan Tang, William D Fraser, Craig Sale
PURPOSE: To investigate the effect of feeding carbohydrate and protein (CHO+PRO), immediately or 2 h after an exhaustive run, on the bone turnover response in endurance runners. METHODS: 10 men (age 28±5 y, height 1.74±0.05 m, body mass 69.7±6.3 kg) performed treadmill running at 75%VO2max, until exhaustion, on three occasions. Blood was collected before and immediately, 1, 2, 3, 4 and 24 h post-exercise, for measurement of β-CTX, P1NP, PTH, PO4, ACa and Ca...
January 24, 2017: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/28080896/traumatic-foreign-body-pericarditis-in-a-toco-toucan-ramphastos-toco
#8
Mireia Máinez, Jorge Rosell, Roger Such, Teresa Cardona, Carles Juan-Sallés
An approximately 10-yr-old, captive-born female toco toucan ( Ramphastos toco ) was presented due to an acute onset of depression and apathy. On visual and physical examination, it showed an abnormal posture and dehydration, respectively. Serum biochemistry revealed hyperuricemia (39.4 mg/dl) and elevated glutamic oxaloacetic transaminase (GOT; 1,050 U/L). Radiographs demonstrated an enlargement of the cardiac silhouette. The bird died 7 days after presentation, despite treatment with enrofloxacin, allopurinol, a preparation of hepatorenal protectors, and complex B vitamins with dextrose...
December 2016: Journal of Zoo and Wildlife Medicine: Official Publication of the American Association of Zoo Veterinarians
https://www.readbyqxmd.com/read/28044994/influence-of-l-carnitine-on-stored-rat-blood-a-study-on-plasma
#9
Carl Hsieh, Vani Rajashekharaiah
OBJECTIVE: Plasma acts as a good indicator of oxidative stress in blood. L-carnitine is an antioxidant that reduces metabolic stress in cells, thereby providing a protective effect against oxidative stress. L-carnitine as an additive in storage has not been explored. Thus, this study attempts to analyze the role of L-carnitine in blood storage solution, Citrate Phosphate Dextrose Adenine (CPDA)-1 through oxidative stress (OS) markers - antioxidant enzymes, lipid peroxidation and protein oxidation...
December 30, 2016: Turkish Journal of Haematology: Official Journal of Turkish Society of Haematology
https://www.readbyqxmd.com/read/28043554/pathological-bacteriological-and-molecular-characteristics-of-natural-outbreaks-of-johne-s-disease-in-goats-of-fars-province-iran
#10
F Zarei Kordshouli, A Khodakaram Tafti, M Haghkhah
OBJECTIVE/BACKGROUND: Johne's disease, also called paratuberculosis, is a very important chronic infectious disease of ruminants worldwide. The causative agent is an acid-fast bacterium, Mycobacterium avium paratuberculosis (MAP). Finding a precise method for detecting MAP is essential for the control and eradication of this disease in small ruminant herds. METHODS: In this study, appropriate samples were obtained from the ileum, cecum, colon, and mesenteric lymph nodes of 10 suspected naturally infected goats...
December 2016: International Journal of Mycobacteriology
https://www.readbyqxmd.com/read/28017745/negative-pressure-hydrocephalus-a-case-report-on-successful-treatment-under-intracranial-pressure-monitoring-with-bilateral-ventriculoperitoneal-shunts
#11
Sajan Pandey, Yi Jin, Liang Gao, Cheng Cheng Zhou, Da Ming Cui
BACKGROUND: Negative-pressure hydrocephalus (NegPH), a very rare condition of unknown etiology and optimal treatment, usually presents postneurosurgery with clinical and imaging features of hydrocephalus, but with negative cerebrospinal fluid pressure. CASE DESCRIPTION: We describe a NegPH case of -3 mm Hg intracranial pressure that was successfully treated to achieve 5 mm Hg under continuous intracranial pressure monitoring with horizontal positioning, head down and legs elevated to 10°-15°, neck wrapping for controlled venous drainage, chest and abdomen bandages, infusion of 5% dextrose fluid to lower plasma osmolarity (Na(+), 130-135 mmol/L), daily cerebrospinal fluid drainage >200 mL, and arterial blood gas partial pressure of carbon dioxide >40 mm Hg...
December 23, 2016: World Neurosurgery
https://www.readbyqxmd.com/read/28012568/improved-survival-after-induction-of-sepsis-by-cecal-slurry-in-pd-1-knockout-murine-neonates
#12
Whitney A Young, Eleanor A Fallon, Daithi S Heffernan, Philip A Efron, William G Cioffi, Alfred Ayala
BACKGROUND: Sepsis and the ensuing immune dysfunction continue to be major contributors to neonatal morbidity and mortality. Neonatal sepsis also is associated with profound immune dysfunction. We have recently identified a role for a family of coinhibitory molecules that are altered in murine sepsis and in critically ill adult patients, which may be a target for development of novel therapies. There is, however, a paucity of data pertaining to the role of coinhibitory checkpoint proteins in the control and modulation of neonatal sepsis...
December 21, 2016: Surgery
https://www.readbyqxmd.com/read/28007721/physical-compatibility-of-ceftolozane-tazobactam-with-selected-i-v-drugs-during-simulated-y-site-administration
#13
Abrar K Thabit, Yukihiro Hamada, David P Nicolau
PURPOSE: Results of a study to examine the physical compatibility of ceftolozane-tazobactam with common i.v. medications during simulated Y-site administration are presented. METHODS: Ceftolozane-tazobactam was reconstituted according to manufacturer recommendations and diluted with 0.9% sodium chloride or 5% dextrose to solutions containing 15 mg (10 mg of ceftolozane and 5 mg of tazobactam)/mL. All other i.v. drugs were prepared according to manufacturer recommendations and diluted with 0...
January 1, 2017: American Journal of Health-system Pharmacy: AJHP
https://www.readbyqxmd.com/read/28006007/improving-the-diet-for-the-rearing-of-glossina-brevipalpis-newstead-and-glossina-austeni-newstead-blood-source-and-collection-processing-feeding-procedures
#14
Chantel J De Beer, Gert J Venter, Marc J B Vreysen
One of the challenges to maintain tsetse fly (Diptera: Glossinidae) colonies is the sustainable supply of high quality blood meals. The effect of using anticoagulants during collection of the blood, the addition of phagostimulants to the blood meals as well as using mixtures of bovine and porcine blood in different proportions for feeding on colony productivity was assessed. Defibrinated bovine blood was found to be suitable to maintain both the Glossina brevipalpis Newstead and Glossina austeni Newstead colonies...
2016: PloS One
https://www.readbyqxmd.com/read/28002935/growth-performance-nutrients-digestibility-and-blood-metabolites-of-lambs-fed-diets-supplemented-with-probiotics-during-pre-and-post-weaning-period
#15
Atef M Saleem
Objective: Two experiments were conducted to evaluate the effects of inclusion of a commercial probiotic (PRO) contains a mixture of two strains of Pediococcus, Pediococcus acidilactici (1 x 106 cfu/g) and Pediococcus pentosaceus (1.3 x 106 cfu/g), with a dextrose as the carrier compound to a diet based on concentrate mixture and wheat straw on growth performance, digestibility, and blood metabolites of lambs during pre- and post-weaning period. Methods: In exp...
December 17, 2016: Asian-Australasian Journal of Animal Sciences
https://www.readbyqxmd.com/read/28001016/effect-of-dapagliflozin-administration-on-metabolic-syndrome-insulin-sensitivity-and-insulin-secretion
#16
Manuel González-Ortiz, Miriam Méndez-Del Villar, Esperanza Martínez-Abundis, Alejandra M Ramírez-Rodríguez
AIM: To evaluate the effect of dapagliflozin on metabolic syndrome (MetS), insulin sensitivity and insulin secretion. METHODS: A randomized, double blind, placebo-controlled clinical trial was carried out in 24 patients with MetS. Glucose and insulin levels were measured every 30 min for 2-h after a 75-g dextrose load. Metabolic profile was also evaluated before and after the pharmacological intervention. Twelve patients received dapagliflozin (10 mg) before breakfast for 90 days...
December 20, 2016: Minerva Endocrinologica
https://www.readbyqxmd.com/read/27994924/correlation-between-amitriptyline-induced-cardiotoxic-effects-and-cardiac-s100b-protein-in-isolated-rat-hearts
#17
Nil Hocaoğlu, Nergis Murat, Serap Cilaker Mıcılı, Burç Aydın, Bekir Uğur Ergür, Şule Kalkan
BACKGROUND: Amitriptyline is an important cause of mortality due to its cardiovascular toxicity. AIMS: To investigate the changes in levels of cardiac S100b protein on amitriptyline-induced cardiotoxicity and also to examine the correlation between amitriptyline-induced cardiotoxic effects and cardiac S100b protein in an isolated rat heart model. STUDY DESIGN: Animal experimentation, isolated heart model. METHODS: After a stabilization period, isolated hearts were randomized to two groups (n=5 and n=7)...
November 2016: Balkan Medical Journal
https://www.readbyqxmd.com/read/27994804/microbial-profile-of-corneal-ulcers-in-a-tertiary-care-hospital-in-south-india
#18
Chittur Y Ranjini, Vishnu V Waddepally
PURPOSE: To identify the prevalence and microbial profile of infectious keratitis in a tertiary eye care hospital, and to test for the in vitro antimicrobial resistance of the bacterial isolates. METHODS: A total of 312 patients presenting to a tertiary eye care hospital with infected corneal ulcer were enrolled in this study. Their socio-demographic data and risk factors were recorded. Corneal scrapings collected from the edge of the ulcer were processed for direct gram stain and KOH mount...
October 2016: Journal of Ophthalmic & Vision Research
https://www.readbyqxmd.com/read/27931081/presence-and-distribution-of-yeasts-in-the-reproductive-tract-of-healthy-female-horses
#19
A Azarvandi, A R Khosravi, H Shokri, M Talebkhan Garoussi, F Gharahgouzlou, G Vahedi, A Sharifzadeh
BACKGROUND: Yeasts are commensal organisms found in the reproductive and gastrointestinal tracts, and on the skin and other mucosa in mammals. OBJECTIVES: The purpose of this study was to isolate and identify the yeast flora in the caudal reproductive tract of healthy female horses. STUDY DESIGN: Longitudinal study. METHODS: A total of 453 samples were collected using double guarded swabs from the vestibule, clitoral fossa and vagina of 151 horses...
December 8, 2016: Equine Veterinary Journal
https://www.readbyqxmd.com/read/27930743/effects-of-four-weeks-of-%C3%AE-alanine-supplementation-on-repeated-sprint-ability-in-water-polo-players
#20
Gabriel Motta Pinheiro Brisola, Guilherme Giannini Artioli, Marcelo Papoti, Alessandro Moura Zagatto
The purpose of this study was to investigate the effect of four weeks of β-alanine supplementation on repeated sprint ability in water polo players. Twenty-two male water polo players participated in the study, divided randomly into two homogeneous groups (placebo and β-alanine groups). The study design was double-blind, parallel and placebo controlled. Before and after the supplementation period (28 days), the athletes performed two specific repeated sprint ability tests interspaced by a 30-minute swimming test...
2016: PloS One
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