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https://www.readbyqxmd.com/read/28936435/impact-of-enhanced-recovery-after-surgery-protocols-on-postoperative-morbidity-and-mortality-in-patients-undergoing-routine-hepatectomy-review-of-the-current-evidence
#1
Rahul Damania, Andrei Cocieru
BACKGROUND: Enhanced recovery protocols are widely used in many areas of general surgery but had a limited penetration in perioperative management of patients undergoing liver resection. Recently, multiple publications described application of enhanced recovery after surgery (ERAS) program to hepatectomy patients but their definitive role is not established or accepted by hepatobiliary surgeons. METHODS: A comprehensive literature review of published series in English language medical sources detailing ERAS program application for hepatectomy for the period of 2006-2016 is performed...
September 2017: Annals of Translational Medicine
https://www.readbyqxmd.com/read/28900996/-clinicopathologic-characteristics-and-prognosis-of-gastric-hepatoid-adenocarcinoma
#2
Rongfei Zhao, Xinxin Wang, Xin Lan, Mingsen Li
OBJECTIVE: To investigate the clinicopathological characteristics, diagnosis, treatment and prognosis of gastric hepatoid adenocarcinoma(HAS). METHODS: Retrospective analysis of clinicopathological data of 24 cases with gastric HAS diagnosed by surgery and pathology in Chinese PLA General Hospital from January 2013 to May 2016 were carried out. All the patients underwent preoperative serum alpha fetoprotein (AFP), carcinoembryonic antigen (CEA), endoscopy and imaging examination (CT or B-mode ultrasonography), and those with elevated AFP were excluded from liver cancer, cirrhosis, endodermal sinus tumor and other diseases...
September 25, 2017: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/28900442/impact-of-preoperative-three-dimensional-computed-tomography-cholangiography-on-postoperative-resection-margin-status-in-patients-operated-due-to-hilar-cholangiocarcinoma
#3
A Andert, P Bruners, C Heidenhain, F Ulmer, C D Klink, P H Alizai, C Kuhl, U P Neumann, M Binnebösel
INTRODUCTION: The purpose of this study was to analyse the value of 3-dimensional computed tomography cholangiography (3D-ERC) compared to conventional retrograde cholangiography in the preoperative diagnosis of hilar cholangiocarcinoma (HC) with special regard to the resection margin status (R0/R1). PATIENTS AND METHODS: All hepatic resections performed between January 2011 and November 2013 in patients with HC at the Department of General, Visceral and Transplant Surgery of the RWTH Aachen University Hospital were analysed...
2017: Gastroenterology Research and Practice
https://www.readbyqxmd.com/read/28895097/combination-therapies-for-primary-hepatic-neuroendocrine-carcinoma-a-case-report
#4
Richi Nakatake, Morihiko Ishizaki, Kosuke Matui, Hiroaki Yanagimoto, Kentaro Inoue, Masaki Kaibori, Yusai Kawaguchi, Masanori Kon
BACKGROUND: Primary hepatic neuroendocrine carcinomas are extremely rare. Because of the rarity of PHNEC, its clinical features and treatment outcomes are not well understood. A proper diagnosis and the correct therapeutic approach therefore remain clinically challenging. CASE PRESENTATION: A 67-year-old man was admitted to our department because of a liver tumor. Computed tomography revealed a single liver tumor 50 mm in diameter and located in the S3 region. Biopsy and imaging findings resulted in a diagnosis of primary hepatic neuroendocrine carcinoma...
September 11, 2017: Surgical Case Reports
https://www.readbyqxmd.com/read/28892958/correlation-of-serum-prolactin-level-to-child-pugh-scoring-system-in-cirrhosis-of-liver
#5
Chaitanya H Balakrishnan, H Rajeev
INTRODUCTION: With the growing incidence of liver cirrhosis among Asians, the use of a biomarker such as prolactin, indicates the severity of the disease, its complications and serves as a tool for early intervention. AIM: To compare the efficacy of serum prolactin to the Child Pugh scoring system in cirrhosis of the liver and establish that serum prolactin is an early marker for complications of cirrhosis of the liver. MATERIALS AND METHODS: This was a comparative study on 60 patients admitted to the Department of General Medicine, KIMS from June 2014 to November 2015...
July 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28881379/trends-in-major-upper-abdominal-surgery-for-cancer-in-octogenarians-has-there-been-a-change-in-patient-selection
#6
Madalyn G Neuwirth, Christine Bierema, Andrew J Sinnamon, Douglas L Fraker, Rachel R Kelz, Robert E Roses, Giorgos C Karakousis
BACKGROUND: Although there is a general perception that, as the older population grows in number, more are undergoing surgery, there are few data on trends in major resections for cancer and short-term outcomes in this group. METHODS: The Nationwide Inpatient Sample was (NIS) used to estimate the national trends of major upper abdominal resections (esophagus, stomach, liver, pancreas) for cancer in octogenarians (aged ≥80 years) from 2001 to 2011. Resection rates performed per year were incidence-adjusted within this age group for each cancer type as determined by the NIS database...
September 7, 2017: Cancer
https://www.readbyqxmd.com/read/28865456/the-effect-of-preoperative-liver-dysfunction-on-cardiac-surgery-outcomes
#7
Luiz Araujo, Viktor Dombrovskiy, Wali Kamran, Ashleigh Lemaire, Antonio Chiricolo, Leonard Y Lee, Anthony Lemaire
BACKGROUND: To determine the impact of preoperative Liver Dysfunction (LD) on outcomes after elective Coronary Artery Bypass Grafting (CABG) and Valvular surgery (VS). METHODS: The Nationwide Inpatient Sample (2002-2010) was queried to identify patients with LD who had elective CABG or VS utilizing ICD-9-CM diagnosis and procedure codes. These patients were matched with the similar patients without LD (controls) by propensity score matching. Chi-square and Wilcoxon rank sum tests were used for analysis...
September 2, 2017: Journal of Cardiothoracic Surgery
https://www.readbyqxmd.com/read/28861314/new-surgical-technique-applied-with-urological-instruments-in-bilobar-multiple-hepatolithiasis-ultra-mini-percutaneous-hepatolithotomy
#8
Ahmet Öztürk, Mehmet Giray Sönmez, Süleyman Bakdık, Yunus Emre Göger, Mehmet Serkan Özkent, Faruk Aksoy, Metin Belviranlı
Intrahepatic bile duct stones may emerge with manifestations as chronic stomach ache, cholestasis, cholangitis, abscess, post-obstructive atrophy and liver cirrhosis presentation may occur. Thus the treatment of symptomatic hepatolithiasis patients should be provided. Different methods such as biliary decompression, endoscopic, percutaneous or open surgery are recommended for the treatment of patients with intrahepatic gallstones. The aim of the treatment is to extract the stones and regain biliary drainage...
September 2017: Turkish Journal of Urology
https://www.readbyqxmd.com/read/28858385/pathological-factors-impacting-prognosis-of-resected-liver-metastases-of-colorectal-carcinoma-implications-and-proposal-for-a-pathological-reporting-protocol
#9
REVIEW
Gilton Marques Fonseca, Paulo Herman, Sheila Friedrich Faraj, Jaime Arthur Pirola Kruger, Fabricio Ferreira Coelho, Vagner Birk Jeismann, Ivan Cecconello, Venancio Avancini Ferreira Alves, Timothy M Pawlik, Evandro Sobroza de Mello
Colorectal cancer is a leading cause of death worldwide. The liver is the most common site of distant metastases and surgery is the only potentially curative treatment, although recurrence following surgery is high. In order to define prognosis after surgery, many histopathological features have been identified in the primary tumor. In turn, pathologists routinely report specific findings to guide oncologists about the decision to recommend adjuvant therapy. In general, the pathological report of resected colorectal liver metastases is limited to confirmation of the malignancy and details regarding the margins status...
August 31, 2017: Histopathology
https://www.readbyqxmd.com/read/28858130/effect-of-bispectral-index-guided-anesthesia-on-consumption-of-anesthetics-and-early-postoperative-cognitive-dysfunction-after-liver-transplantation-an-observational-study
#10
Ying-Hao Cao, Ping Chi, Yan-Xing Zhao, Xi-Chen Dong
The objective of this study was to summarize the incidence of postoperative cognitive dysfunction (POCD) after 7days following liver transplantation (LT), and to evaluate the effectiveness of bispectral index (BIS) guided anesthetic intervention in reducing POCD. Additional serum concentrations of S100β and neuron-specific enolase (NSE) were detected during surgery to determine whether they were reliable predictors of POCD.Patients who underwent LT at Beijing YouAn Hospital Affiliated to Capital University of Medical Science from January 2014 to December 2015 were enrolled...
September 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28845130/anaesthetic-challenges-in-cancer-patients-current-therapies-and-pain-management
#11
Jūratė Gudaitytė, Dominykas Dvylys, Indrė Šimeliūnaitė
THE OBJECTIVE: The aim is to present the major effects of cancer treatment (chemotherapy, radiotherapy, surgery) that the anaesthesiologist should consider preoperatively, and to review techniques of the analgesic management of the disease. MATERIALS AND METHODS: To summarize the major challenges that cancer patients present for the anaesthesiologists, a literature review was conducted. Articles presenting evidence or reviewing the possible effects of anaesthetics on cancer cells were also included...
2017: Acta medica Lituanica
https://www.readbyqxmd.com/read/28840497/defining-long-term-survivors-following-resection-of-intrahepatic-cholangiocarcinoma
#12
Fabio Bagante, Gaya Spolverato, Matthew Weiss, Sorin Alexandrescu, Hugo P Marques, Luca Aldrighetti, Shishir K Maithel, Carlo Pulitano, Todd W Bauer, Feng Shen, George A Poultsides, Oliver Soubrane, Guillaume Martel, B Groot Koerkamp, Alfredo Guglielmi, Endo Itaru, Timothy M Pawlik
BACKGROUND: Intrahepatic cholangiocarcinoma (ICC) is an aggressive primary tumor of the liver. While surgery remains the cornerstone of therapy, long-term survival following curative-intent resection is generally poor. The aim of the current study was to define the incidence of actual long-term survivors, as well as identify clinicopathological factors associated with long-term survival. METHODS: Patients who underwent a curative-intent liver resection for ICC between 1990 and 2015 were identified using a multi-institutional database...
August 24, 2017: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
https://www.readbyqxmd.com/read/28835248/long-term-survival-following-hepatectomy-radiation-and-chemotherapy-for-recurrent-pancreatic-carcinoma-a-case-report
#13
Shigeru Fujisaki, Motoi Takashina, Ryouichi Tomita, Kenichi Sakurai, Tadatoshi Takayama
BACKGROUND: Recurrent pancreatic carcinoma (PC) is generally well known to have a poor prognosis. Cases in which multidisciplinary treatments have been remarkably effective are rare. CASE PRESENTATION: Herein, we reported a case of long-term survival following a combination of hepatectomy for a liver metastasis and radiation and chemotherapy for abdominal lymph node metastases after a curative pancreaticoduodenectomy for PC. A 51-year-old Japanese man underwent a pancreaticoduodenectomy following a PC diagnosis in December 2011...
August 23, 2017: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28822820/utility-of-3d-reconstruction-of-2d-liver-computed-tomography-magnetic-resonance-images-as-a-surgical-planning-tool-for-residents-in-liver-resection-surgery
#14
Caitlin T Yeo, Andrew MacDonald, Tamas Ungi, Andras Lasso, Diederick Jalink, Boris Zevin, Gabor Fichtinger, Sulaiman Nanji
OBJECTIVE: A fundamental aspect of surgical planning in liver resections is the identification of key vessel tributaries to preserve healthy liver tissue while fully resecting the tumor(s). Current surgical planning relies primarily on the surgeon's ability to mentally reconstruct 2D computed tomography/magnetic resonance (CT/MR) images into 3D and plan resection margins. This creates significant cognitive load, especially for trainees, as it relies on image interpretation, anatomical and surgical knowledge, experience, and spatial sense...
August 16, 2017: Journal of Surgical Education
https://www.readbyqxmd.com/read/28799151/contrast-enhanced-ultrasound-features-of-hepatocellular-carcinoma-not-detected-during-the-screening-procedure
#15
Yi Dong, Wen-Ping Wang, Feng Mao, Christoph Dietrich
Aim The aim of this retrospective study is to report on the characteristics of contrast-enhanced ultrasound (CEUS) of primarily not detected hepatocellular carcinoma (HCC) during the screening procedure of patients at risk. Methods Sixty-four patients with a finally solitary and histologically proven HCC not detected HCC during the screening procedure were retrospectively analyzed. Most of HCC lesions (90.6 %, 58/64) measured < 20 mm in diameter. All HCC lesions were not detected during the initial screening procedure but suspected using contrast-enhanced magnetic resonance imaging...
August 2017: Zeitschrift Für Gastroenterologie
https://www.readbyqxmd.com/read/28793278/mixed-adenoneuroendocrine-carcinoma-derived-from-the-cystic-duct-a-case-report
#16
Yu-Ki Takemoto, Tomoyuki Abe, Hironobu Amano, Keiji Hanada, Akihito Okazaki, Tomoyuki Minami, Tsuyoshi Kobayashi, Masahiro Nakahara, Shuji Yonehara, Hideki Ohdan, Toshio Noriyuki
INTRODUCTION: Mixed adenoneuroendocrine carcinomas (MANECs) derived from cystic duct are extremely rare. PRESENTATION OF CASE: An 80-year-old woman was admitted to the department of surgery, Onomichi general hospital with abnormal liver function and jaundice. Enhanced abdominal computed tomography (CT) detected a well-enhanced papillary tumor in the cystic duct, which protruded into the common bile duct. The intrahepatic bile duct was dilated due to tumor obstruction...
July 13, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/28767807/model-of-a-training-program-in-robotic-surgery-and-its-initial-results
#17
Fernando Athayde Veloso Madureira, José Luís Souza Varela, Delta Madureira, Luis Alfredo Vieira D'Almeida, Fábio Athayde Veloso Madureira, Alexandre Miranda Duarte, Otávio Pires Vaz, José Reinan Ramos
Objective: to describe the implementation of a training program in robotic surgery and to point the General Surgery procedures that can be performed with advantages using the robotic platform. Methods: we conducted a retrospective analysis of data collected prospectively from the robotic surgery group in General and Colo-Retal Surgery at the Samaritan Hospital (Rio de Janeiro, Brazil), from October 2012 to December 2015. We describe the training stages and particularities...
May 2017: Revista do Colégio Brasileiro de Cirurgiões
https://www.readbyqxmd.com/read/28763918/-the-association-between-single-nucleotide-polymorphisms-in-il6-il10-genes-and-the-susceptibility-to-primary-hepatic-carcinoma-in-shunde-district-of-foshan-city
#18
X L Wang, X Ye, X F Yu, H Ding, Q Liu, L Liu, S D Chen
Objective: To investigate the association between single nucleotide polymorphisms (SNP) in cytokine IL6, IL10 genes and the susceptibility to primary hepatic carcinoma(PHC) of Shunde district in Guangdong Province. Methods: Patients from two hospitals in Shunde District of Foshan City were selected from October 2010 to October 2012. Case group inclusion criteria includedprimary liver cancer; local residents of Shunde or living in Shunde for more than 10 years. The control group inclusion criteria included: patients visited ENT, general surgery and physical examination department in the same hospital during the same period; Local residents or living in Shunde for 10 years and above...
August 6, 2017: Zhonghua Yu Fang Yi Xue za Zhi [Chinese Journal of Preventive Medicine]
https://www.readbyqxmd.com/read/28758562/thromboelastrography-teg-is-still-relevant-in-the-21st-century-as-a-point-of-care-test-for-monitoring-coagulation-status-in-the-cardiac-surgical-suite
#19
Antonio Hernandez Conte, Deena Perotti, Lauren Farac
Since their introduction into clinical practice in the early 1960s, viscoelastic point-of-care (POC) testing-thromboelastrography (TEG) and thromboelastrometry (ROTEM)-has become increasingly popular in intensive care units, operating rooms, and emergency room settings. As TEG has been an established POC viscoelastic testing modality for many years, there has been more research and analysis of its utility and ability to reduce transfusions in the general, cardiac, and liver surgical sectors compared with ROTEM...
September 2017: Seminars in Cardiothoracic and Vascular Anesthesia
https://www.readbyqxmd.com/read/28757837/hypoxic-hepatitis-during-the-perioperative-period-in-patients-with-severe-pulmonary-disease-and-cor-pulmonale
#20
Hyuckgoo Kim, Sang-Jin Park, Deokhee Lee
Hypoxic hepatitis (HH) is characterized by marked and transient elevations in liver enzyme levels in the absence of other potential causes of liver injury. Although rare, it can occur in the presence of hemodynamic instability and hypoxemia in patients with cor pulmonale. We report two cases of perioperative HH in patients with severe pulmonary disease and cor pulmonale. The first case is of a patient with cor pulmonale who underwent hemiarthroplasty for a femur fracture. Transient hypotension developed during spinal anesthesia and severe hypoxemia were observed in the postoperative period...
July 2017: Saudi Journal of Anaesthesia
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