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Prosthesis metal allergy

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https://www.readbyqxmd.com/read/27881114/hypersensitivity-reactions-to-metal-implants-laboratory-options
#1
Anna Maria Carossino, Christian Carulli, Simone Ciuffi, Roberto Carossino, Giorgia Donata Zappoli Thyrion, Roberto Zonefrati, Massimo Innocenti, Maria Luisa Brandi
BACKGROUND: All implant compounds undergo an electrochemical process when in contact with biological fluids, as well as mechanical corrosion due to abrasive wear, with production of metal debris that may inhibit repair processes. None of the commonly-used methods can diagnose implant allergies when used singly, therefore a panel of tests should be performed on allergic patients as pre-operative screening, or when a postoperative metal sensitisation is suspected. METHODS: We analysed patients with painful prostheses and subjects prone to allergies using the Patch Test in comparison with the Lymphocyte Transformation Test...
November 23, 2016: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/26573458/a-comparative-analysis-of-metal-allergens-associated-with-dental-alloy-prostheses-and-the-expression-of-hla-dr-in-gingival-tissue
#2
COMPARATIVE STUDY
Xin Zhang, Li-Cheng Wei, Bin Wu, Li-Ying Yu, Xiao-Ping Wang, Yue Liu
The present study aimed to provide guidance for the selection of prosthodontic materials and the management of patients with a suspected metal allergy. This included a comparison of the sensitivity of patients to alloys used in prescribed metal‑containing prostheses, and correlation analysis between metal allergy and accompanying clinical symptoms of sensitized patients using a patch test. The results from the patch test and metal component analyses were processed to reach a final diagnosis. In the present study, four dental alloys were assessed...
January 2016: Molecular Medicine Reports
https://www.readbyqxmd.com/read/25979449/cobalt-chromium-alloys-in-dentistry-an-evaluation-of-metal-ion-release
#3
Maria Claudia Lucchetti, Giovanni Fratto, Federica Valeriani, Elisabetta De Vittori, Saverio Giampaoli, Patrizia Papetti, Vincenzo Romano Spica, Licia Manzon
STATEMENT OF PROBLEM: Metal ions released into the oral cavity from dental prosthesis alloys may damage the cellular metabolism or proliferation and cause hypersensitivity or allergies. The oral cavity environment is particularly prone to corrosion due to saliva, microorganisms, and pH variations. PURPOSE: The purpose of this in vitro study was to evaluate the ion release of chromium, cobalt, and iron from the Co-Cr alloys used for traditionally cast and computer-aided design/computer-aided manufacturing dental devices after interaction with oral bacteria and different pH conditions...
October 2015: Journal of Prosthetic Dentistry
https://www.readbyqxmd.com/read/25874392/-bone-cement-adhesion-on-ceramic-surfaces-surface-activation-of-retention-surfaces-of-knee-prostheses-by-atmospheric-plasma-versus-thermal-surface-treatment
#4
B Marx, R Marx, U Reisgen, D Wirtz
AIM: CoCrMo alloys are contraindicated for allergy sufferers. For these patients, uncemented and cemented prostheses made of titanium alloy are indicated. Knee prostheses machined from that alloy, however, may have poor tribological behaviour, especially in relation to UHMWPE inlays. Therefore, for knee replacement cemented high-strength oxide ceramic prostheses are suitable for allergy sufferers and in cases of particle-induced aseptic loosening. For adhesion of bone cement, the ceramic surface, however, only exposes inefficient mechanical retention spots as compared with a textured metal surface...
April 2015: Zeitschrift Für Orthopädie und Unfallchirurgie
https://www.readbyqxmd.com/read/25820838/survivorship-and-clinical-outcome-of-birmingham-hip-resurfacing-a-minimum-ten-years-follow-up
#5
Md Quamar Azam, Stephen McMahon, Gabrielle Hawdon, Sukesh Rao Sankineani
INTRODUCTION: Resurfacing as a percentage of total hip arthroplasty rose from 5.6 % in 2001 to 8.9 % in 2005 in Australia. During the same period the resurfacing to conventional prosthesis rose from 19.6 % to 29 % in the younger age group (less than 55 years). Long term (more than ten years) functional results of BHR are sparingly documented. Among the literatures available, the patient selection criteria vary from osteoarthritis, avascular necrosis, and dysplastic hip to slipped capital femoral epiphysis...
January 2016: International Orthopaedics
https://www.readbyqxmd.com/read/25695869/diagnosis-and-management-of-patients-with-allergy-to-metal-implants
#6
REVIEW
Peter Thomas, Burkhard Summer
Cutaneous allergic reactions to implanted metal devices, for example, orthopedic, are well reported in the literature. Also, extracutaneous complications resulting from peri-implant inflammation have been observed in association with metal allergy. Nickel, cobalt, and chromium are the three most common triggers of both cutaneous and extracutaneous allergy-related complications. However, the diagnosis of metal implant allergy remains a challenge, that is, the synopsis of excluding differential diagnoses and the combination of different allergy diagnostic tools is needed...
April 2015: Expert Review of Clinical Immunology
https://www.readbyqxmd.com/read/25582229/the-association-between-metal-allergy-total-knee-arthroplasty-and-revision-study-based-on-the-danish-knee-arthroplasty-register
#7
COMPARATIVE STUDY
Henrik J Münch, Stig S Jacobsen, Jens T Olesen, Torkil Menné, Kjeld Søballe, Jeanne D Johansen, Jacob P Thyssen
BACKGROUND AND PURPOSE: It is unclear whether delayed-type hypersensitivity reactions against implanted metals play a role in the etiopathogenesis of malfunctioning total knee arthroplasties. We therefore evaluated the association between metal allergy, defined as a positive patch test reaction to common metal allergens, and revision surgery in patients who underwent knee arthroplasty. PATIENTS AND METHODS: The nationwide Danish Knee Arthroplasty Register, including all knee-implanted patients and revisions in Denmark after 1997 (n = 46,407), was crosslinked with a contact allergy patch test database from the greater Copenhagen area (n = 27,020)...
June 2015: Acta Orthopaedica
https://www.readbyqxmd.com/read/25230805/-the-spectrum-of-histomorphological-findings-related-to-joint-endoprosthetics
#8
REVIEW
L Morawietz, V Krenn
Approximately 230,000 total hip and 170,000 knee joint endoprostheses are implanted in Germany annually of which approximately 10% (i.e. 40,000 interventions per year) are cases of revision surgery. These interventions involve removal of a previously implanted prosthesis which has resulted in complaints and replacement with a new prosthesis. There are manifold reasons for revision surgery, the most common indication being so-called endoprosthesis loosening, which is subdivided into septic and aseptic loosening...
November 2014: Der Pathologe
https://www.readbyqxmd.com/read/25087797/metal-allergy-to-titanium-bars-after-the-nuss-procedure-for-pectus-excavatum
#9
Kazuhiro Sakamoto, Kohei Ando, Daisuke Noma
The Nuss procedure requires the placement of metal bars in the chest cage to repair pectus excavatum. Metal allergies are one of the complications associated with this procedure. Given that titanium is a biocompatible metal, it induces few allergic symptoms. Therefore, titanium bars are recommended for patients with metal sensitivity. We report the case of a 17-year-old boy with pectus excavatum who had a metal allergy to titanium bars, which occurred after the Nuss procedure. The administration of oral steroids is useful for treating metal allergies...
August 2014: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/25017027/a-new-volar-plate-made-of-carbon-fiber-reinforced-polyetheretherketon-for-distal-radius-fracture-analysis-of-40-cases
#10
Luigi Tarallo, Raffaele Mugnai, Roberto Adani, Francesco Zambianchi, Fabio Catani
BACKGROUND: Implants based on the polyetheretherketon (PEEK) polymer have been developed in the last decade as an alternative to conventional metallic devices. PEEK devices may provide several advantages over the use of conventional orthopedic materials, including the lack of metal allergies, radiolucency, low artifacts on magnetic resonance imaging scans and the possibility of tailoring mechanical properties. The purpose of this study was to evaluate the clinical results at 12-month follow-up using a new plate made of carbon-fiber-reinforced polyetheretherketon for the treatment of distal radius fractures...
December 2014: Journal of Orthopaedics and Traumatology: Official Journal of the Italian Society of Orthopaedics and Traumatology
https://www.readbyqxmd.com/read/24949984/prevalence-of-self-reported-metal-allergy-in-patients-undergoing-primary-total-knee-arthroplasty
#11
Adam D Bloemke, Henry D Clarke
No validated screening method exists to identify patients at risk for metal allergy complications following total knee arthroplasty (TKA). Select use of implants that do not contain nickel, cobalt, and chromium may be considered in patients at risk. This study was performed to determine the rate of self-reported cutaneous metal allergy, or sensitivity, in patients undergoing knee replacement, and to evaluate whether there is a higher prevalence in females. A retrospective chart review was performed on 194 consecutive patients who underwent primary knee arthroplasty with a single surgeon between 2010 and 2011...
June 2015: Journal of Knee Surgery
https://www.readbyqxmd.com/read/24941404/metal-sensitivities-among-tja-patients-with-post-operative-pain-indications-for-multi-metal-ltt-testing
#12
Marco S Caicedo, Edward Solver, Latasha Coleman, Nadim James Hallab
Metal sensitivity testing is generally the diagnosis method of last resort for aseptic painful implants with elevated inflammatory responses. However, the relationship between implant-related pain and implant-debris-related metal sensitization remains incompletely understood. Although a sensitivity to nickel alone has been used as a general measure of metal allergy, it may lack the specificity to correlate sensitivity to specific implant metals and thus to select a biologically appropriate implant material...
2014: Journal of Long-term Effects of Medical Implants
https://www.readbyqxmd.com/read/24941403/evaluation-and-management-of-metal-hypersensitivity-in-total-joint-arthroplasty-a-systematic-review
#13
REVIEW
Michael Amini, Wesley H Mayes, Alice Tzeng, Tony H Tzeng, Khaled J Saleh, William M Mihalko
Metal hypersensitivity has been an identified problem in orthopedics for nearly half a century, but its implications remain unclear. Establishing which total joint arthroplasty (TJA) candidates may do poorly with conventional implants and which patients would benefit from revision to an allergen-free implant remains challenging. Our systematic search of the MEDLINE database identified 52 articles for inclusion in our review. Case reports revealed that half of patients presented with pain and swelling, while only one-third presented with cutaneous symptoms...
2014: Journal of Long-term Effects of Medical Implants
https://www.readbyqxmd.com/read/24935833/-comparative-study-of-sensitivity-of-different-dental-metal-materials
#14
Yue Liu, Xiao-ping Wang, Bin Wu, Yue Hu, Xia Dou, Hong-ying Sun, Ya-tong Ding, Xin Zhang
PURPOSE: To compare the sensitivity of different dental metal materials, in order to provide references for choosing of dental metal materials. METHODS: Patch test was performed on 92 patients wearing dental metal prosthesis. Pearson Chi-square test, corrected Chi-square test and Fisher exact test were used for statistical analysis with SPSS17.0 software package. RESULTS: (1)The sensitivity rates of different metal materials were different...
April 2014: Shanghai Kou Qiang Yi Xue, Shanghai Journal of Stomatology
https://www.readbyqxmd.com/read/24930546/metal-release-and-metal-allergy-after-total-hip-replacement-with-resurfacing-versus-conventional-hybrid-prosthesis
#15
RANDOMIZED CONTROLLED TRIAL
Klas Gustafson, Stig S Jakobsen, Nina D Lorenzen, Jacob P Thyssen, Jeanne D Johansen, Charlotte M Bonefeld, Maiken Stilling, Thomas Baad-Hansen, Kjeld Søballe
BACKGROUND: Metal-on-metal (MOM) total hip arthroplasties were reintroduced because of the problems with osteolysis and aseptic loosening related to polyethylene wear of early metal-on-polyethylene (MOP) arthroplasties. The volumetric wear rate has been greatly reduced with MOM arthroplasties; however, because of nano-size wear particles, the absolute number has been greatly increased. Thus, a source of metal ion exposure with the potential to sensitize patients is present. We hypothesized that higher amounts of wear particles result in increased release of metal ions and ultimately lead to an increased incidence of metal allergy...
August 2014: Acta Orthopaedica
https://www.readbyqxmd.com/read/24711136/what-are-the-current-clinical-issues-in-wear-and-tribocorrosion
#16
REVIEW
Daniel J Berry, Matthew P Abdel, John J Callaghan
Wear and corrosion in joint arthroplasty are important causes of failure. From the standpoint of current clinical importance, there are four main categories of wear and tribocorrosion: polyethylene wear, ceramic-on-ceramic (CoC) bearing wear, metal-on-metal (MoM) bearing wear, and taper tribocorrosion. Recently, problems with wear in the knee have become less prominent as have many issues with hip polyethylene (PE) bearings resulting from the success of crosslinked PE. However, MoM articulations and taper tribocorrosion have been associated with soft tissue inflammatory responses, and as a result, they have become prominent clinical concerns...
December 2014: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/24685961/percutaneous-closure-of-patent-foramen-ovale-with-atriasept-ii-device-in-nickel-allergic-patients
#17
Valeria Cammalleri, Gian Paolo Ussia, Massimo Marchei, Saverio Muscoli, Domenico Sergi, Massimiliano Macrini, Francesco Romeo
There are concerns about percutaneous closure of patent foramen ovale (PFO) using nitinol-alloys devices in patients with nickel hypersensitivity. We describe our experience with Atriasept II (Cardia Eagan, Minnesota, USA) used in four patients with known nickel allergy. No intraprocedural or in-hospital adverse events occurred. The follow-up was negative for allergic manifestations, without complications, as assessed by echocardiography. Because of the risk of adverse outcomes in nickel-allergic patients, devices with higher biocompatibility, low-profile, and low nickel content should be preferred in cases of known hypersensitivity...
April 2014: Journal of Cardiovascular Medicine
https://www.readbyqxmd.com/read/24664194/internal-lengthening-device-for-congenital-femoral-deficiency-and-fibular-hemimelia
#18
Lior Shabtai, Stacy C Specht, Shawn C Standard, John E Herzenberg
BACKGROUND: Patients with congenital limb shortening can present with joint instability, soft tissue contractures, and significant leg length discrepancy. Classically, lengthening is done with external fixation, which can result in scarring, pin site infection, loss of motion, and pain. We therefore developed an alternative to this approach, a new, controllable, internal lengthening device for patients with congenital limb shortening. QUESTIONS/PURPOSES: We evaluated this device in terms of (1) healing index, (2) complications, (3) accuracy of the device's external controller, and (4) adjacent-joint ROM...
December 2014: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/24389947/total-knee-arthroplasty-in-patients-with-hypersensitivity-to-metals
#19
Massimo Innocenti, Christian Carulli, Fabrizio Matassi, Anna Maria Carossino, Maria Luisa Brandi, Roberto Civinini
PURPOSE: We evaluated the risk of hypersensitivity to metals in a population of consecutive subjects undergoing a total knee arthroplasty (TKA). We also proposed a diagnostic pathway to address any sensitivity to metals. We finally presented the mid-term outcomes of a full non allergenic knee implant. METHODS: We developed a protocol based on the medical history, patch testing, and on specific laboratory assays, in order to assess a sensitization to metals. Twenty-four patients (25 knees) with referred or suspected allergy to metals were found in more than 1,000 treated patients, with a mean age of 72...
February 2014: International Orthopaedics
https://www.readbyqxmd.com/read/24201465/metal-hypersensitivity-reactions-to-implants-opinions-and-practices-of-patch-testing-dermatologists
#20
Peter C Schalock, Jacob P Thyssen
BACKGROUND: Cutaneous metal hypersensitivity reactions (MHR) are common but rare with implanted devices. OBJECTIVES: This study aimed to characterize the opinions of dermatologists who are actively evaluating/advising patients with MHR. METHODS: A questionnaire was distributed to all individuals who attended the European Society of Contact Dermatitis (ESCD) 2012 and the American Contact Dermatitis Society 2013 meetings. RESULTS: A total of 119 individuals responded with a participation rates of 10% (ESCD) and 32% (American Contact Dermatitis Society)...
November 2013: Dermatitis
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