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https://www.readbyqxmd.com/read/28441542/reattachment-using-the-suture-bridge-augmentation-for-achilles-tendon-avulsion-fracture-with-osteoporotic-bony-fragment
#1
Byung-Ki Cho, Ji-Kang Park, Seung-Myung Choi
Although avulsion fractures of the calcaneal tuberosity are rare injuries, these can be a challenging problem with frequent complications, such as loss of reduction and soft tissue problem. Anatomical reduction and internal fixation are indicated to avoid these pitfalls and to restore function of the triceps surae. However, the best fixation device and operative technique are still controversial. A case that achieved satisfactory clinical outcome through a reattachment technique using the suture bridge augmentation for Achilles tendon avulsion fracture with osteoporotic bony fragment is presented...
April 15, 2017: Foot
https://www.readbyqxmd.com/read/28441120/prevalence-of-trachoma-in-northern-benin-results-from-11-population-based-prevalence-surveys-covering-26-districts
#2
Amadou Alfa Bio, Pelagie M Boko, Yannelle A Dossou, Jean-Jacques Tougoue, Achille Kabore, Ignace Sounouvou, Jean-Eudes Biaou, Lionel Nizigama, Paul Courtright, Anthony W Solomon, Lisa Rotondo, Wilfrid Batcho, Dorothée Kinde-Gazard
AIMS: We sought to evaluate trachoma prevalence in all suspected-endemic areas of Benin. METHODS: We conducted population-based surveys covering 26 districts grouped into 11 evaluation units (EUs), using a two-stage, systematic and random, cluster sampling design powered at EU level. In each EU, 23 villages were systematically selected with population proportional to size; 30 households were selected from each village using compact segment sampling. In selected households, we examined all consenting residents aged one year or above for trichiasis, trachomatous inflammation - follicular (TF), and trachomatous inflammation - intense...
April 25, 2017: Ophthalmic Epidemiology
https://www.readbyqxmd.com/read/28438861/vitamin-c-improves-therapeutic-effects-of-adipose-derived-stem-cell-transplantation-in-mouse-tendonitis-model
#3
Kyung-Ku Kang, Eun-Joo Lee, Youg-Deuk Kim, Myung-Jin Chung, Jun-Young Kim, Shin-Yoon Kim, Su-Kyeung Hwang, Kyu-Shik Jeong
BACKGROUND/AIM: We hypothesized that combined therapy using adipose-derived stem cells (ASCs) and vitamin C might improve tendon regeneration in tendonitis. To determine combined effects of ASC transplantation with vitamin C, we used senescence marker protein 30 (SMP30)-knockout (KO) mice that cannot biosynthesize vitamin C by themselves. MATERIALS AND METHODS: SMP30-KO were divided into four groups: Control, vitamin C, ASCs, and vitamin C plus ASCs. Tendonitis was induced in the achilles tendons via injection of collagenase type I...
May 2017: In Vivo
https://www.readbyqxmd.com/read/28436746/penetration-time-profiles-for-two-class-3b-lasers-in-in-situ-human-achilles-at-rest-and-stretched
#4
Daniel Huseby Bordvik, Sturla Haslerud, Ingvill Fjell Naterstad, Rodrigo Alvaro Brandão Lopes-Martins, Ernesto Cesar Pinto Leal Junior, Jan Magnus Bjordal, Jon Joensen
BACKGROUND AND OBJECTIVE: The majority of studies investigating penetration of laser light are performed in vitro on skin flaps, with measures of immediate penetration depth and energy loss. The aim of this study was to investigate the penetration time profiles for two different lasers used in low-level laser therapy, during 150 sec of exposure both in stretched and relaxed human Achilles in situ. MATERIALS AND METHODS: Thirty-four Achilles tendons from 17 healthy volunteers were irradiated by an 810 nm, 200 mW, continuous- and a 904 nm, 60 mW, super-pulsed laser...
April 21, 2017: Photomedicine and Laser Surgery
https://www.readbyqxmd.com/read/28434578/50-years-ago-in-the-journal-of-pediatrics-the-normal-achilles-tendon-reflex-time-in-children-as-measured-with-the-photomograph
#5
Paul Graham Fisher
No abstract text is available yet for this article.
May 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/28426920/dabigatran-enhances-platelet-reactivity-and-platelet-thrombin-receptor-expression-in-patients-with-atrial-fibrillation-comment
#6
Laurent Bonello, Marc Laine, Laurence Camoin-Jau, Corinne Frere
We read with interest the article by Achilles et al. [1] in a recent issue of the Journal of Thrombosis and Haemostasis, in which the authors raised a concern regarding the safety of the oral direct thrombin inhibitor (ODTI) dabigatran. The authors aimed to investigate a potential mechanism involved in the increased risk of myocardial infarction (MI) observed in several trials of patients treated with dabigatran when compared head-to-head with patients treated with indirectly acting therapeutic anticoagulants...
April 20, 2017: Journal of Thrombosis and Haemostasis: JTH
https://www.readbyqxmd.com/read/28426894/characteristics-and-course-of-enthesitis-in-a-juvenile-idiopathic-arthritis-inception-cohort
#7
Dax G Rumsey, Jaime Guzman, Alan M Rosenberg, Adam M Huber, Rosie Scuccimarri, Natalie J Shiff, Alessandra Bruns, Brian M Feldman, Dean T Eurich
Objective To describe the prevalence, associated characteristics, and course of enthesitis in a juvenile idiopathic arthritis (JIA) inception cohort. Methods Canadian children newly diagnosed with JIA between 2005 and 2010 were categorized using ILAR criteria at the 6-month visit and followed in the ReACCh-Out cohort for up to 5 years. The presence of entheseal tenderness on examination at 33 sites shown on a homunculus was recorded at 0, 6, 12, 18, 24, 36, 48 and 60 months after enrolment. Enthesitis was defined as entheseal tenderness at more than one site or on more than one occasion...
April 20, 2017: Arthritis Care & Research
https://www.readbyqxmd.com/read/28424882/effectiveness-of-dry-needling-and-high-volume-image-guided-injection-in-the-management-of-chronic-mid-portion-achilles-tendinopathy-in-adult-population-a-literature-review
#8
REVIEW
F A Chaudhry
Achilles tendinopathy is a common overuse condition affecting the adult population. The incidence is on the rise because of greater participation of people in recreational or competitive sporting activities. There are several treatment options available both non-operative and operative. Ultrasound-guided dry needling and high-volume image-guided injection is relatively a new procedure. The aim of this study was to find out the effectiveness of dry needling and HVIGI in the management of mid-portion chronic Achilles tendinopathy by performing a literature review...
April 19, 2017: European Journal of Orthopaedic Surgery & Traumatology: Orthopédie Traumatologie
https://www.readbyqxmd.com/read/28422132/haploinsufficiency-for-ankrd11-flanking-genes-makes-the-difference-between-kbg-and-16q24-3-microdeletion-syndromes-12-new-cases
#9
Francesca Novara, Berardo Rinaldi, Sanjay M Sisodiya, Antonietta Coppola, Sabrina Giglio, Franco Stanzial, Francesco Benedicenti, Alan Donaldson, Joris Andrieux, Rachel Stapleton, Astrid Weber, Paolo Reho, Conny van Ravenswaaij-Arts, Wilhelmina S Kerstjens-Frederikse, Joris Robert Vermeesch, Koenraad Devriendt, Carlos A Bacino, Andrée Delahaye, S M Maas, Achille Iolascon, Orsetta Zuffardi
16q24 deletion involving the ANKRD11 gene, ranging from 137 kb to 2 Mb, have been associated with a microdeletion syndrome characterized by variable cognitive impairment, autism spectrum disorder, facial dysmorphisms with dental anomalies, brain abnormalities essentially affecting the corpus callosum and short stature. On the other hand, patients carrying either deletions encompassing solely ANKRD11 or its loss-of-function variants were reported in association with the KBG syndrome, characterized by a very similar phenotype, including mild-to-moderate intellectual disability, short stature and macrodontia of upper incisors, with inter and intrafamilial variability...
April 19, 2017: European Journal of Human Genetics: EJHG
https://www.readbyqxmd.com/read/28419370/distinguishing-industrial-meat-from-that-of-indigenous-chickens-with-molecular-markers
#10
Dominga Soglia, Paola Sacchi, Stefano Sartore, Sandra Maione, Achille Schiavone, Michele De Marco, Maria Teresa Bottero, Alessandra Dalmasso, Daniele Pattono, Roberto Rasero
The aim of investigation was to evaluate a traceability system to detect industrial chicken meat among indigenous products, considering issues that could affect assignment accuracy. The dataset included 2 Italian indigenous meat breeds, namely Bionda Piemontese (2 ecotypes) and Bianca di Saluzzo, one broiler line, and 3 layer lines. Assignment tests were performed using a standard panel of 28 microsatellite loci. To evaluate effects of inbreeding and substructure on assignment accuracy, a simulated dataset was prepared...
April 17, 2017: Poultry Science
https://www.readbyqxmd.com/read/28419324/improving-data-workflow-systems-with-cloud-services-and-use-of-open-data-for-bioinformatics-research
#11
Md Rezaul Karim, Audrey Michel, Achille Zappa, Pavel Baranov, Ratnesh Sahay, Dietrich Rebholz-Schuhmann
Data workflow systems (DWFSs) enable bioinformatics researchers to combine components for data access and data analytics, and to share the final data analytics approach with their collaborators. Increasingly, such systems have to cope with large-scale data, such as full genomes (about 200 GB each), public fact repositories (about 100 TB of data) and 3D imaging data at even larger scales. As moving the data becomes cumbersome, the DWFS needs to embed its processes into a cloud infrastructure, where the data are already hosted...
April 16, 2017: Briefings in Bioinformatics
https://www.readbyqxmd.com/read/28418988/hiv-specific-cd8-t-cells-producing-ccl-4-are-associated-with-worse-immune-reconstitution-during-chronic-infection
#12
Rita Casetti, Carmela Pinnetti, Alessandra Sacchi, Gabriele De Simone, Veronica Bordoni, Eleonora Cimini, Nicola Tumino, Francesca Besi, Domenico Viola, Federica Turchi, Valentina Mazzotta, Andrea Antinori, Federico Martini, Adriana Ammassari, Chiara Agrati
BACKGROUND: Immunological non response represents the Achilles heel in the combination antiretroviral treatment (cART) effectiveness, and increases risk of clinical events and death. CD8 T cells play a crucial role in controlling HIV replication and polyfunctional HIV-specific CD8 T cells have been associated with non-progressive HIV infection. However, the possible role of polyfunctional CD8 T cells in predicting post-treatment immune reconstitution has not yet been explored. The aim of this study was to identify functional markers predictive of immunological response to cART in chronic HIV-infected patients...
April 7, 2017: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/28418825/science-to-practice-quantitative-us-elastography-can-be-used-to-quantify-mechanical-and-histologic-tendon-healing-in-a-rabbit-model-of-achilles-tendon-transection
#13
Kenneth S Lee, Jack Martin, Darryl Thelen
Compression-based ultrasonographic (US) elastography is associated with time-dependent mechanical and histologic changes of the healing tendon in a transected rabbit model of the Achilles tendon. This finding will lead to continued development of quantitative US, which can be used to objectively assess a diseased or healing tendon. With advances in the method used, clinical translation of tendon elastography may enable clinicians to diagnose tendon damage and track healing, which should improve both treatment and outcome...
May 2017: Radiology
https://www.readbyqxmd.com/read/28415688/inhibitor-sbfi26-suppresses-the-malignant-progression-of-castration-resistant-pc3-m-cells-by-competitively-binding-to-oncogenic-fabp5
#14
Waseem Al-Jameel, Xiaojun Gou, Shiva S Forootan, Majed Saad Al Fayi, Philip S Rudland, Farzad S Forootan, Jiacheng Zhang, Philip A Cornford, Syed A Hussain, Youqiang Ke
Castration resistant-prostate cancer is largely impervious to feather hormonal therapy and hence the outlook for patients is grim. Here we use an approach to attach the recently discovered Achilles heel. The experimental treatment established in this study is based on the recent discovery that it is the FABP5-PPARγ-VEGF signalling axis, rather than the androgen receptor pathway, played a dominant role in promoting the malignant progression of castration resistant prostate cancer cells. Treatments have been established in mice by suppressing the biological activity of FABP5 using a chemical inhibitor SBFI26...
March 9, 2017: Oncotarget
https://www.readbyqxmd.com/read/28413894/isolated-gastrocnemius-recession-for-the-treatment-of-achilles-tendinopathy
#15
Kenneth S Smith, Caleb Jones, Zachariah Pinter, Ashish Shah
BACKGROUND: Various treatment modalities have been described for Achilles tendinopathy with varying degrees of success. The rationale for the gastrocnemius recession procedure is to decrease the mechanical overload of the Achilles tendon arising from an equinus contracture. METHODS: We retrospectively reviewed 25 patients who underwent an isolated gastrocnemius recession procedure at our institution between May 2013 and April 2015 by a single surgeon. Clinical outcome was evaluated on the basis of pain, utilizing visual analog scale (VAS) scores and the Foot Function Index (FFI) by telephonic interview...
April 1, 2017: Foot & Ankle Specialist
https://www.readbyqxmd.com/read/28413884/incidence-and-risk-factors-of-venous-thromboembolism-after-orthopaedic-foot-and-ankle-surgery
#16
Jamal Ahmad, Mary-Katherine Lynch, Mitchell Maltenfort
BACKGROUND: This study examines the incidence and risk of postoperative symptomatic venous thromboembolism (VTE) after orthopaedic foot/ankle surgery. MATERIALS: Patients that received foot/ankle surgery between 2006 and 2016 were reviewed. Inclusion criteria were surgical patients that were without coagulopathy, previous VTE, and/or using anticoagulation medications including aspirin. Age, sex, body mass index, medical comorbidities, and surgical diagnosis and procedure(s) were noted...
April 1, 2017: Foot & Ankle Specialist
https://www.readbyqxmd.com/read/28412025/the-influence-of-chronic-il-6-exposure-in-vivo-on-rat-achilles-tendon-extracellular-matrix
#17
Mark S Katsma, Shivam H Patel, Erica Eldon, Kathryn A Corbell, Kevin L Shimkus, James D Fluckey, Chad C Carroll
When compared to placebo, acetaminophen (APAP) reduces tendon stiffness and collagen cross-linking. APAP also enhances the exercise-induced increase in peritendinous levels of IL-6. Elevated levels of IL-6 are associated with tendinopathy, thus we hypothesized that chronic, elevated peritendinous IL-6 would alter tendon extracellular matrix (ECM). IL-6 (∼3000pgml(-1)) was injected (3dwk(-1) for 8-wks) into the Achilles peritendinous region of male Wistar rats (n=16) with the opposite leg serving as a sham...
April 13, 2017: Cytokine
https://www.readbyqxmd.com/read/28411765/hepatic-artery-disease-and-anastomotic-bile-leaks-after-liver-transplantation-shining-the-light-on-the-true-achilles-heel
#18
EDITORIAL
Irene Peñas-Herrero, Manuel Perez-Miranda
No abstract text is available yet for this article.
May 2017: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/28410782/posterior-arthroscopic-tibiotalar-arthrodesis-anatomic-feasibility-study
#19
Louis Malekpour, Said Rahali, Damien Potage, Fabrice Duparc, Franck Dujardin, Xavier Roussignol
Anterior arthroscopic tibiotalar arthrodesis has been well codified. A posterior approach with the patient in prone position is indicated when the anterior approach is precluded by soft tissue issues or for a 1-step procedure associated with posterior subtalar fusion. In an anatomic study, we assessed the feasibility of posterior arthroscopic tibiotalar fusion and sought to determine the arthroscopy entry points, mortise cartilage freshening quality, and risk of osseous, tendinous, vascular, and neural complications...
April 11, 2017: Journal of Foot and Ankle Surgery: Official Publication of the American College of Foot and Ankle Surgeons
https://www.readbyqxmd.com/read/28409510/combined-osteopathy-and-exercise-management-of-achilles-tendinopathy-in-an-athlete-a-case-report
#20
Georgia Ross, Chris Macfarlane, Brett Vaughan
Mid-portion Achilles tendinopathy is a common injury in sporting populations. There is conflicting evidence about the best approach to conservative management. This report focuses on the rehabilitation of an Achilles tendinopathy utilising osteopathic manual therapy (OMT) and a structured exercise program in a semi-professional volleyballer. The patient presented with a 4-month history of right mid-portion Achilles tendon pain that begun after a lateral inversion sprain of the right ankle. The primary complaint was pain impacting the patients vertical jump performance...
April 13, 2017: Journal of Sports Medicine and Physical Fitness
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