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https://www.readbyqxmd.com/read/27921216/neural-correlates-of-rumination-in-adolescents-with-remitted-major-depressive-disorder-and-healthy-controls
#1
Katie L Burkhouse, Rachel H Jacobs, Amy T Peters, Olu Ajilore, Edward R Watkins, Scott A Langenecker
The aim of the present study was to use fMRI to examine the neural correlates of engaging in rumination among a sample of remitted depressed adolescents, a population at high risk for future depressive relapse. A rumination induction task was used to assess differences in the patterns of neural activation during rumination versus a distraction condition among 26 adolescents in remission from major depressive disorder (rMDD) and in 15 healthy control adolescents. Self-report depression and rumination, as well as clinician-rated depression, were also assessed among all participants...
December 5, 2016: Cognitive, Affective & Behavioral Neuroscience
https://www.readbyqxmd.com/read/27917000/emotional-working-memory-training-as-an-online-intervention-for-adolescent-anxiety-and-depression-a-randomised-controlled-trial
#2
E Leone de Voogd, Reinout W Wiers, Robert J Zwitser, Elske Salemink
OBJECTIVE: Anxiety and depression are highly prevalent disorders in adolescence. They are associated with deficits in working memory (WM), which also appears to increase rumination, worry, and negative mood. WM training, especially in an emotional context, might help in reducing or preventing these disorders. The current study investigated the direct effects of online emotional WM training on WM capacity, and short- and long-term effects on symptoms of anxiety and depression, and secondary measures of emotional functioning...
September 2016: Australian Journal of Psychology
https://www.readbyqxmd.com/read/27913990/sirukumab-a-potential-treatment-for-mood-disorders
#3
REVIEW
Aileen J Zhou, Yena Lee, Giacomo Salvadore, Benjamin Hsu, Trehani M Fonseka, Sidney H Kennedy, Roger S McIntyre
Convergent evidence indicates that abnormalities in the innate immune system may be pertinent to the pathogenesis, phenomenology, and possible treatment of several mental disorders. In keeping with this view, the targeting of interleukin-6 with the human monoclonal antibody sirukumab may represent a possible treatment and disease modification approach, for adults with brain-based disorders (e.g., major depressive disorder). A PubMed/Medline database search was performed using the following search terms: sirukumab; anti-IL-6; IL-6; major depressive disorder; inflammation...
December 2, 2016: Advances in Therapy
https://www.readbyqxmd.com/read/27898709/individual-differences-in-emotion-regulation-childhood-trauma-and-proneness-to-shame-and-guilt-in-adolescence
#4
Aurora Szentágotai-Tătar, Andrei C Miu
Dispositional shame and guilt have been associated with psychopathology and an increasing number of studies have traced this relation back to adolescence. This developmental period is thought to be characterized by maturational changes in emotion regulation, which also play an important role in vulnerability to psychopathology, but little is known about the links between emotion regulation and dispositional shame and guilt. The current study investigated the relations between individual differences in the habitual use of a wide range of emotion regulation strategies and proneness to shame and guilt in a large sample of adolescents (N = 706), aged 13 to 17 years...
2016: PloS One
https://www.readbyqxmd.com/read/27894469/the-association-of-perseverative-negative-thinking-with-depression-anxiety-and-emotional-distress-in-people-with-long-term-conditions-a-systematic-review
#5
Leanne Trick, Edward Watkins, Stacey Windeatt, Chris Dickens
OBJECTIVE: Depression is common in people with long term conditions, and is associated with worse medical outcomes. Previous research shows perseverative negative thinking (e.g. worry, rumination) predicts subsequent depression and worse medical outcomes, suggesting interventions targeting perseverative negative thinking could improve depression and medical outcomes. Previous studies recruited healthy individuals, however. This review aimed to determine the temporal relationship and strength of prospective association of perseverative negative thinking with depression, anxiety and emotional distress in people with long term conditions...
December 2016: Journal of Psychosomatic Research
https://www.readbyqxmd.com/read/27880789/targeting-ruminative-thinking-in-adolescents-at-risk-for-depressive-relapse-rumination-focused-cognitive-behavior-therapy-in-a-pilot-randomized-controlled-trial-with-resting-state-fmri
#6
Rachel H Jacobs, Edward R Watkins, Amy T Peters, Claudia G Feldhaus, Alyssa Barba, Julie Carbray, Scott A Langenecker
: This pilot randomized control trial was designed to examine whether Rumination-Focused Cognitive Behavior Therapy (RFCBT) reduces rumination and residual depressive symptoms among adolescents with a history of Major Depressive Disorder (MDD) who are at risk for relapse. We also examined whether these changes in symptoms were associated with changes in functional connectivity of the posterior cingulate cortex (PCC), a key node in the default mode network (DMN). Thirty-three adolescents (ages 12-18) were randomized to eight weeks of RFCBT or an assessment only (AO) control...
2016: PloS One
https://www.readbyqxmd.com/read/27870434/do-sex-differences-in-rumination-explain-sex-differences-in-depression
#7
REVIEW
Tracey J Shors, Emma M Millon, Han Yan M Chang, Ryan L Olson, Brandon L Alderman
It is generally accepted that women tend to ruminate more than men do and these thought patterns are often associated with depressive symptoms (Nolen-Hoeksema et al., ). Based on these findings, we considered whether the relationship between rumination and depression is stronger in women than in men and if so, whether this might explain the higher prevalence of major depressive disorder (MDD) in women and finally, whether the association can be disrupted through a mind/body intervention. Adult men and women, most of whom were clinically depressed, participated in an intervention known as MAP Training, which combines "mental" training with silent meditation and "physical" training with aerobic exercise (Shors et al...
January 2, 2017: Journal of Neuroscience Research
https://www.readbyqxmd.com/read/27862615/the-reciprocal-relationship-between-bipolar-disorder-and-social-interaction-a-qualitative-investigation
#8
Rebecca Owen, Patricia Gooding, Robert Dempsey, Steven Jones
BACKGROUND: Evidence suggests that social support can influence relapse rates, functioning and various clinical outcomes in people with bipolar disorder. Yet 'social support' is a poorly defined construct, and the mechanisms by which it affects illness course in bipolar disorder remain largely unknown. Key aims of this study were to ascertain which facets of social interaction affect mood management in bipolar disorder, and how symptoms of bipolar disorder can influence the level of support received...
November 13, 2016: Clinical Psychology & Psychotherapy
https://www.readbyqxmd.com/read/27858293/cognitive-vulnerabilities-to-depression-for-adolescents-in-single-mother-and-two-parent-families
#9
Issar Daryanani, Jessica L Hamilton, Brae Anne McArthur, Laurence Steinberg, Lyn Y Abramson, Lauren B Alloy
Although research consistently suggests that adolescents in single-mother families are at increased risk for depression, the mechanisms that explain this relationship are unclear. In a community sample of adolescents (N = 368; ages 12-16; 50 % female; 50 % White) and their mothers (42 % single), adolescents completed measures of depressive symptoms, rumination, and depressogenic inferential style at baseline and two yearly follow-ups. Mothers reported on stressful events that occurred in the child's life from birth until baseline...
November 17, 2016: Journal of Youth and Adolescence
https://www.readbyqxmd.com/read/27853428/goal-directed-worry-rules-are-associated-with-distinct-patterns-of-amygdala-functional-connectivity-and-vagal-modulation-during-perseverative-cognition
#10
Frances Meeten, Graham C L Davey, Elena Makovac, David R Watson, Sarah N Garfinkel, Hugo D Critchley, Cristina Ottaviani
Excessive and uncontrollable worry is a defining feature of Generalized Anxiety Disorder (GAD). An important endeavor in the treatment of pathological worry is to understand why some people are unable to stop worrying once they have started. Worry perseveration is associated with a tendency to deploy goal-directed worry rules (known as "as many as can" worry rules; AMA). These require attention to the goal of the worry task and continuation of worry until the aims of the "worry bout" are achieved. This study examined the association between the tendency to use AMA worry rules and neural and autonomic responses to a perseverative cognition induction...
2016: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/27832698/the-association-between-attention-control-anxiety-and-depression-the-indirect-effects-of-repetitive-negative-thinking-and-mood-recovery
#11
Sarah J Kertz, Kimberly T Stevens, Keith P Klein
BACKGROUND AND OBJECTIVES: Attention control deficits and repetitive negative thinking (RNT; i.e., rumination) may be key factors in the development and persistence of depression and anxiety, although their role in symptom development remains poorly understood. This represents a gap in the literature, as interventions targeting attention control and associated RNT may enhance interventions and prevent costly relapse. The current study was designed to examine the serial indirect effects of transdiagnostic RNT and negative affect recovery following a lab-induced stressor on the association between attention control deficits and trait anxiety and depression...
November 19, 2016: Anxiety, Stress, and Coping
https://www.readbyqxmd.com/read/27829693/practicing-emotionally-biased-retrieval-affects-mood-and-establishes-biased-recall-a-week-later
#12
Janna N Vrijsen, Paula T Hertel, Eni S Becker
Cognitive Bias Modification (CBM) can yield clinically relevant results. Only few studies have directly manipulated memory bias, which is prominent in depression. In a new approach to CBM, we sought to simulate or oppose ruminative processes by training the retrieval of negative or positive words. Participants studied positive and negative word pairs (Swahili cues with Dutch translations). In the positive and negative conditions, each of the three study trials was followed by a cued-recall test of training-congruent translations; a no-practice condition merely studied the pairs...
2016: Cognitive Therapy and Research
https://www.readbyqxmd.com/read/27809880/investigating-the-cost-effectiveness-of-attention-bias-modification-abm-for-outpatients-with-major-depressive-disorder-mdd-a-randomized-controlled-trial-protocol
#13
Gina R A Ferrari, Eni S Becker, Filip Smit, Mike Rinck, Jan Spijker
BACKGROUND: Despite the range of available, evidence-based treatment options for Major Depressive Disorder (MDD), the rather low response and remission rates suggest that treatment is not optimal, yet. Computerized attention bias modification (ABM) trainings may have the potential to be provided as cost-effective intervention as adjunct to usual care (UC), by speeding up recovery and bringing more patients into remission. Research suggests, that a selective attention for negative information contributes to development and maintenance of depression and that reducing this negative bias might be of therapeutic value...
November 3, 2016: BMC Psychiatry
https://www.readbyqxmd.com/read/27794448/testing-the-attentional-scope-model-of-rumination-an-eye-tracking-study-using-the-moving-window-paradigm
#14
Lin Fang, Alvaro Sanchez, Ernst H W Koster
The attentional scope model of rumination predicts that rumination is associated with a narrowed attentional scope which magnifies emotional responding and reduces problem-solving. This study examined this prediction by using a moving window paradigm, allowing for a more direct measurement of attentional scope at a perceptual level. High and low trait ruminators were asked to read self-related and other-related sentences under small, medium, large, and no moving window conditions while their visual fixations during reading were recorded...
October 26, 2016: Biological Psychology
https://www.readbyqxmd.com/read/27790863/identity-processes-and-statuses-in-patients-with-and-without-eating-disorders
#15
Margaux Verschueren, Koen Luyckx, Erin A Kaufman, Maarten Vansteenkiste, Philip Moons, Ellen Sleuwaegen, Ann Berens, Katrien Schoevaerts, Laurence Claes
Problems with identity formation are associated with a range of psychiatric disorders. Yet, the mechanisms underlying such problems and how they are refined into specific diagnostic presentations require further investigation. The present study investigated identity processes among 123 women with eating disorders (ED) and age-matched community controls via a newly developed identity model. Several clinical outcome variables were assessed. Patients with ED scored lower on committing to and identifying with identity-related choices and scored higher on maladaptive or ruminative exploration, identity diffusion and identity disorder...
October 27, 2016: European Eating Disorders Review: the Journal of the Eating Disorders Association
https://www.readbyqxmd.com/read/27747141/pubertal-development-emotion-regulatory-styles-and-the-emergence-of-sex-differences-in-internalizing-disorders-and-symptoms-in-adolescence
#16
Lauren B Alloy, Jessica L Hamilton, Elissa J Hamlat, Lyn Y Abramson
Adolescence marks the emergence of sex differences in internalizing symptoms and disorders, with girls at increased risk for depression and anxiety during the pubertal transition. However, the mechanisms through which puberty confers risk for internalizing psychopathology for girls, but not boys, remain unclear. We examined two pubertal indicators (pubertal status and timing) as predictors of the development of emotion regulation styles (rumination and emotional clarity) and depressive and anxiety symptoms and disorders in a three-wave study of 314 adolescents...
September 2016: Clinical Psychological Science
https://www.readbyqxmd.com/read/27743536/the-future-oriented-repetitive-thought-fort-scale-a-measure-of-repetitive-thinking-about-the-future
#17
Regina Miranda, Alyssa Wheeler, Lillian Polanco-Roman, Brett Marroquín
BACKGROUND AND OBJECTIVES: Repetitive thinking about the future has been suggested as one way in which individuals may become hopeless about the future. We report on a new scale assessing future-oriented repetitive thinking, termed the Future-Oriented Repetitive Thought (FoRT) Scale. METHODS: In Study 1, an exploratory factor analysis was conducted with data from 1071 individuals who completed the scale. Study 2 describes a confirmatory factor analysis with a revised version of the scale on a sample of 612 individuals, a subsample of whom (N=99) also completed measures of repetitive thought (rumination, worry), hopelessness-related cognitions, and symptoms of depression and generalized anxiety disorder in order to examine evidence for the measure's convergent, discriminant, and concurrent validity...
October 1, 2016: Journal of Affective Disorders
https://www.readbyqxmd.com/read/27736737/sleep-quality-predicts-positive-and-negative-affect-but-not-vice-versa-an-electronic-diary-study-in-depressed-and-healthy-individuals
#18
Mara E J Bouwmans, Elisabeth H Bos, H J Rogier Hoenders, Albertine J Oldehinkel, Peter de Jonge
BACKGROUND: The exact nature of the complex relationship between sleep and affect has remained unclear. This study investigated the temporal order of change in sleep and affect in participants with and without depression. METHODS: 27 depressed patients and 27 pair-matched healthy controls assessed their sleep in the morning and their affect 3 times a day for 30 consecutive days in their natural environment. Daily sleep quality and average positive affect (PA) and negative affect (NA) were used to examine whether changes in sleep quality preceded or followed changes in PA and NA, and whether this was different for patients and healthy controls...
September 29, 2016: Journal of Affective Disorders
https://www.readbyqxmd.com/read/27734198/emotion-regulation-strategies-in-depressive-and-anxiety-symptoms-in-youth-a-meta-analytic-review
#19
Johanna Özlem Schäfer, Eva Naumann, Emily Alexandra Holmes, Brunna Tuschen-Caffier, Andrea Christiane Samson
The role of emotion regulation in subclinical symptoms of mental disorders in adolescence is not yet well understood. This meta-analytic review examines the relationship between the habitual use of prominent adaptive emotion regulation strategies (cognitive reappraisal, problem solving, and acceptance) and maladaptive emotion regulation strategies (avoidance, suppression, and rumination) with depressive and anxiety symptoms in adolescence. Analyzing 68 effect sizes from 35 studies, we calculated overall outcomes across depressive and anxiety symptoms as well as psychopathology-specific outcomes...
October 12, 2016: Journal of Youth and Adolescence
https://www.readbyqxmd.com/read/27712107/light-therapy-with-scheduled-rise-times-in-young-adults-with-delayed-sleep-phase-disorder-therapeutic-outcomes-and-possible-predictors
#20
Katarina Danielsson, Markus Jansson-Fröjmark, Jan-Erik Broman, Agneta Markström
Clinical trials with light therapy (LT) for delayed sleep phase disorder (DSPD) are sparse and little is known about factors that are favorable for improvements. In this study, LT with scheduled rise times was conducted at home for 14 days by 44 participants with DSPD aged 16-26 years. Primary outcomes were sleep onset and sleep offset. Potential predictors were demographic characteristics, chronotype, dim light melatonin onset, the number of days the LT lamp was used, the daily duration of LT, daytime sleepiness, anxiety, depression, worry, and rumination...
August 11, 2016: Behavioral Sleep Medicine
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