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https://www.readbyqxmd.com/read/28529804/unilateral-discomfort-increases-the-use-of-contralateral-side-during-sit-to-stand-transfer
#1
Simisola O Oludare, Charlie C Ma, Alexander S Aruin
Individuals with unilateral impairment perform symmetrical movements asymmetrically. Restoring symmetry of movements is an important goal of rehabilitation. The aim of the study was to evaluate the effect of using discomfort-inducing devices on movement symmetry. Fifteen healthy individuals performed the sit-to-stand (STS) maneuver using devices inducing unilateral discomfort under the left sole and left thigh or right sole and right thigh and without them. 3D body kinematics, ground reaction forces, electrical activity of muscles, and the level of perceived discomfort were recorded...
2017: Rehabilitation Research and Practice
https://www.readbyqxmd.com/read/28522397/cellulose-acetate-poly-lactic-acid-coaxial-wet-electrospun-scaffold-containing-citalopram-loaded-gelatin-nanocarriers-for-neural-tissue-engineering-applications
#2
Mahdi Naseri-Nosar, Majid Salehi, Shahriar Hojjati-Emami
The current study aimed to develop a biodegradable three-dimensional drug-loaded scaffold with the core-shell structured fibrils using coaxial wet-electrospinning for neural tissue engineering application. Poly lactic acid was wet-electrospun as the core, whereas cellulose acetate was fabricated into the fibril's shell. The scaffold then was coated with citalopram-loaded gelatin nanocarriers (CGNs) produced by nanoprecipitation. Scanning electron microscope observation revealed that the fibrils formed a nonwoven structure with the average diameter of ∼950nm...
May 15, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/28520446/-diabetic-foot-syndrome-importance-of-calf-muscles-mr-spectroscopy-in-the-assessment-of-limb-ischemia-and-effect-of-revascularization
#3
Andrea Němcová, Michal Dubský, Alexandra Jirkovská, Petr Šedivý, Miloslav Drobný, Milan Hájek, Monika Dezortová, Robert Bém, Vladimíra Fejfarová, Anna Pyšná
AIM: The standard method for assessment of effect of revascularization in patients with diabetic foot (DF) and critical limb ischemia (CLI) is transcutaneous oxygen pressure (TcPO2). Phosphorus magnetic resonance spectroscopy (31P MRS) enables to evaluate oxidative muscle metabolism that could be impaired in patients with diabetes and its complications. The aim of our study was to compare MRS of calf muscle between patients with DF and CLI and healthy controls and to evaluate the contribution of MRS in the assessment of the effect of revascularization...
2017: Vnitr̆ní Lékar̆ství
https://www.readbyqxmd.com/read/28516387/a-diffusion-weighted-imaging-informed-continuum-model-of-the-rabbit-triceps-surae-complex
#4
M Alipour, K Mithraratne, J Fernandez
The NZ white rabbit is the animal of choice for much experimental work due to its muscular frame and similar response to human diseases, and is one of the few mammals that have had their genome sequenced. However, continuum-level computational models of rabbit muscle detailing fibre architecture are limited in the literature, especially the triceps surae complex (gastrocnemius, plantaris and soleus), which has similar biomechanics and translatable findings to the human. This study presents a geometrical model of the rabbit triceps surae informed with diffusion-weighted imaging (DWI)-based fibres...
May 18, 2017: Biomechanics and Modeling in Mechanobiology
https://www.readbyqxmd.com/read/28515978/variation-in-medial-and-lateral-gastrocnemius-muscle-activity-with-foot-position
#5
Michael Cibulka, April Wenthe, Zach Boyle, Dylan Callier, Adam Schwerdt, Deidra Jarman, Michael J Strube
BACKGROUND: The gastrocnemius has two heads, medial gastrocnemius (MG) and lateral gastrocnemius (LG); little is known how they contract with different foot positions. The MG is more frequently strained than the LG; and gastrocnemius activation pattern altered by foot position may play a role in injury. Leg exercises often use a toe-in versus toe-out foot position to isolate one gastrocnemius head over another. PURPOSE: The purpose of this study was to determine the electromyographic gastrocnemius muscle activity in the toe-out and toe-in foot positions during weight bearing and non-weight bearing activities...
April 2017: International Journal of Sports Physical Therapy
https://www.readbyqxmd.com/read/28515080/effect-of-resistance-exercise-under-conditions-of-reduced-blood-insulin-on-ampk%C3%AE-ser485-491-inhibitory-phosphorylation-and-ampk-pathway-activation
#6
Kohei Kido, Takumi Yokokawa, Satoru Ato, Koji Sato, Satoshi Fujita
Insulin stimulates skeletal muscle glucose uptake via activation of the protein kinase B/Akt (Akt) pathway. Recent studies suggest that insulin down-regulates AMP-activated protein kinase (AMPK) activity via Ser485/491 phosphorylation of the AMPK α-subunit. Thus, lower blood insulin concentrations may induce AMPK signal activation. Acute exercise is one method to stimulate AMPK activation; however, no study has examined the relationship between blood insulin levels and acute resistance exercise-induced AMPK pathway activation...
May 17, 2017: American Journal of Physiology. Regulatory, Integrative and Comparative Physiology
https://www.readbyqxmd.com/read/28513281/short-term-effects-of-kinesio-taping-on-muscle-recruitment-order-during-a-vertical-jump-a-pilot-study
#7
Guillermo Mendez-Rebolledo, Rodrigo Ramirez-Campillo, Eduardo Guzman-Muñoz, Valeska Gatica-Rojas, Alexis Dabanch-Santis, Francisco Diaz-Valenzuela
CONTEXT: Kinesio taping is commonly used in sports and rehabilitation settings with the aim of prevention and treatment of musculoskeletal injuries. However, limited evidence exists regarding the effects of 24 and 72 h of kinesio taping on trunk and lower limb neuromuscular and kinetic performance during a vertical jump. OBJECTIVE: The purpose of this study was to analyze the short-term effects of kinesio taping on the height and ground reaction force during a vertical jump, in addition to trunk and lower limb muscle latency and recruitment order...
May 17, 2017: Journal of Sport Rehabilitation
https://www.readbyqxmd.com/read/28513280/application-of-acoustic-radiation-force-impulse-arfi-elastography-in-imaging-of-delayed-onset-muscle-soreness-doms-a-comparative-analysis-with-3t-mri
#8
Thilo Hotfiel, Marion Kellermann, Bernd Swoboda, Dane Wildner, Tobias Golditz, Casper Grim, Martin Raithel, Michael Uder, Rafael Heiss
CONTEXT: DOMS is one of the most common reasons for impaired muscle performance in sports and is associated with reduced muscle strength and frequently observed both in professional and recreational athletes. OBJECTIVE: To emphasize the diagnostic value of Acoustic Radiation Force Impulse (ARFI) in imaging of Delayed Onset Muscle Soreness by comparing findings to high-resolution 3T MRI T2 weighted sequences. DESIGN: Case series. SETTING: Laboratory environment...
May 17, 2017: Journal of Sport Rehabilitation
https://www.readbyqxmd.com/read/28513277/effect-of-gastrocnemius-kinesio-taping-on-countermovement-jump-performance-and-vertical-stiffness-following-muscle-fatigue
#9
Sahar Boozari, Mohammad Ali Sanjari, Ali Amiri, Ismail Ebrahimi Takamjani
CONTEXT: Kinesio Tape (KT) is a widely used intervention in the fields of sports and rehabilitation. However, its effects on lower extremity behavior during functional activities are not entirely known. OBJECTIVE: To test the hypothesis that application of KT can change performance and vertical stiffness during the countermovement jump (CMJ) before and after a fatigue protocol. DESIGN: A pre and post design to study the effect of KT in two situations, pre- and post-fatigue...
May 17, 2017: Journal of Sport Rehabilitation
https://www.readbyqxmd.com/read/28507996/effects-of-pulsed-electromagnetic-field-with-predatory-stress-on-functional-and-histological-index-of-injured-sciatic-nerve-in-rat
#10
Maryam Tasbih-Forosh, Leila Zarei, Ehsan Saboory, Mehran Bahrami-Bukani
OBJECTIVE: To assess the effect of combination of pulsed electromagnetic fields (PEMF) with predatory stress on transected sciatic nerve regeneration in rats. METHODS: In sham- operated group (SOG) the nerve was manipulated and left intact. The 10-mm rat sciatic nerve gap was created in rats. In transected group (Transected) nerve stumps were sutured to adjacent muscle and in vein graft group (VG) the gap was bridged using an inside-out vein graft. In VG/PEMF group the transected nerve was bridged using vein graft, phosphate buffered saline was administered into the graft and the whole body was exposed to PEMF...
April 2017: Bulletin of Emergency and Trauma
https://www.readbyqxmd.com/read/28507191/lowering-metabolic-rate-mitigates-muscle-atrophy-in-western-fence-lizards
#11
J Balaban, E Azizi
Extended periods of skeletal muscle disuse can cause a significant loss of contractile proteins, which compromises the ability to generate force, mechanical work or power, thus compromising locomotor performance. Several hibernating organisms can resist muscle atrophy despite months of inactivity. This resistance has been attributed to a reduction in body temperature and metabolic rate and activation of physiological pathways that counteract pathways of protein degradation. However, in these systems such strategies are not mutually exclusive and the effects of these mechanisms can be difficult to separate...
May 15, 2017: Journal of Experimental Biology
https://www.readbyqxmd.com/read/28503705/mri-in-neutral-lipid-storage-disease-nlsd
#12
Matteo Garibaldi, Giorgio Tasca, Jordi Diaz-Manera, Pierfancesco Ottaviani, Francesco Laschena, Donatella Pantoli, Simonetta Gerevini, Chiara Fiorillo, Lorenzo Maggi, Elisabetta Tasca, Adele D'Amico, Olimpia Musumeci, Antonio Toscano, Claudio Bruno, Roberto Massa, Corrado Angelini, Enrico Bertini, Giovanni Antonini, Elena Maria Pennisi
Neutral lipid storage disease (NLSD) is a rare inherited disorder of lipid metabolism resulting in lipid droplets accumulation in different tissues. Skeletal muscle could be affected in both two different form of disease: NLSD with myopathy (NLSD-M) and NLSD with ichthyosis (NLSD-I). We present the muscle imaging data of 12 patients from the Italian Network for NLSD: ten patients presenting NLSD-M and two patients with NLSD-I. In NLSD-M gluteus minimus, semimembranosus, soleus and gastrocnemius medialis in the lower limbs and infraspinatus in the upper limbs were the most affected muscles...
May 13, 2017: Journal of Neurology
https://www.readbyqxmd.com/read/28497652/an-isoflavone-enriched-diet-increases-skeletal-muscle-adaptation-in-response-to-physical-activity-in-ovariectomized-rats
#13
Wenya Zheng, Jonas Hengevoß, Sebastian T Soukup, Sabine E Kulling, Mingyong Xie, Patrick Diel
SCOPE: This study was to investigate anabolic adaptation of skeletal muscle in response to an isoflavone (ISO) enriched diet, training and their combinations in ovariectomized (OVX) rats. METHODS AND RESULTS: Female Wistar rats were sedentary, performed treadmill uphill running, received ISOs, or a combination of ISOs and running after ovariectomy. Body weight was increased by OVX. Both ISO and training treatment antagonized this increase. The weights of soleus and gastrocnemius muscles were increased only when training and ISOs were combined...
May 12, 2017: Molecular Nutrition & Food Research
https://www.readbyqxmd.com/read/28497497/simultaneous-measurement-of-macro-and-microvascular-blood-flow-and-oxygen-saturation-for-quantification-of-muscle-oxygen-consumption
#14
Erin K Englund, Zachary B Rodgers, Michael C Langham, Emile R Mohler, Thomas F Floyd, Felix W Wehrli
PURPOSE: To investigate the relationship between blood flow and oxygen consumption in skeletal muscle, a technique called "Velocity and Perfusion, Intravascular Venous Oxygen saturation and T2*" (vPIVOT) is presented. vPIVOT allows the quantification of feeding artery blood flow velocity, perfusion, draining vein oxygen saturation, and muscle T2*, all at 4-s temporal resolution. Together, the measurement of blood flow and oxygen extraction can yield muscle oxygen consumption ( V˙O2) via the Fick principle...
May 11, 2017: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/28496411/calf-compression-sleeves-change-biomechanics-but-not-performance-and-physiological-responses-in-trail-running
#15
Hugo A Kerhervé, Pierre Samozino, Fabrice Descombe, Matthieu Pinay, Guillaume Y Millet, Marion Pasqualini, Thomas Rupp
Introduction: The aim of this study was to determine whether calf compression sleeves (CS) affects physiological and biomechanical parameters, exercise performance, and perceived sensations of muscle fatigue, pain and soreness during prolonged (~2 h 30 min) outdoor trail running. Methods: Fourteen healthy trained males took part in a randomized, cross-over study consisting in two identical 24-km trail running sessions (each including one bout of running at constant rate on moderately flat terrain, and one period of all-out running on hilly terrain) wearing either degressive CS (23 ± 2 mmHg) or control sleeves (CON, <4 mmHg)...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28496106/neuregulin-1-improves-complex-2-mediated-mitochondrial-respiration-in-skeletal-muscle-of-healthy-and-diabetic-mice
#16
Gaël Ennequin, Frederic Capel, Kevin Caillaud, Vivien Chavanelle, Monique Etienne, Allison Teixeira, Xinyan Li, Nathalie Boisseau, Pascal Sirvent
It has been reported that neuregulin1 (NRG1) improves glucose tolerance in healthy and diabetic rodents. In vitro studies also suggest that NRG1 regulates myocyte oxidative capacity. To confirm this observation in vivo, we evaluated the effect on mitochondrial function of an 8-week treatment with NRG1 in db/db diabetic mice and C57BL/6JRJ healthy controls. NRG1 treatment improved complex 2-mediated mitochondrial respiration in the gastrocnemius of both control and diabetic mice and increased mitochondrial complex 2 subunit content by 2-fold...
May 11, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28495045/deterioration-in-gait-and-functional-ambulation-in-children-and-adolescents-with-charcot-marie-tooth-disease-over-12-months
#17
Rachel Kennedy, Kate Carroll, Kade L Paterson, Monique M Ryan, Jennifer L McGinley
Children and adolescents with Charcot-Marie-Tooth disease (CMT) report problems with gait. Little is known about gait changes over time in children with this degenerative disease. This prospective longitudinal study investigated change in spatio-temporal gait parameters and functional ambulation. Two assessments were conducted 12 months apart. Assessments included: barefoot gait on an electronic walkway; functional ambulation with a six minute walk test and the Functional Mobility Scale; and disease severity with the CMT Pediatric Scale...
April 19, 2017: Neuromuscular Disorders: NMD
https://www.readbyqxmd.com/read/28490645/evidence-of-adaptations-of-locomotor-neural-drive-in-response-to-enhanced-intermuscular-connectivity-between-the-triceps-surae-muscles-of-the-rat
#18
Michel Bernabei, Jaap H van Dieën, Huub Maas
The aims of this study were to investigate changes (i) in the coordination of activation of the triceps surae muscle group and (ii) in muscle belly length of soleus (SO) and lateral gastrocnemius (LG) during locomotion (trotting) in response to increased stiffness of intermuscular connective tissues in the rat. We measured muscle activation and muscle belly lengths, as well as hindlimb kinematics, before and after an artificial enhancement of the connectivity between SO and LG muscles obtained by implanting a tissue-integrating surgical mesh at the muscles' interface...
May 10, 2017: Journal of Neurophysiology
https://www.readbyqxmd.com/read/28489606/pantoprazole-blocks-the-jak2-stat3-pathway-to-alleviate-skeletal-muscle-wasting-in-cancer-cachexia-by-inhibiting-inflammatory-response
#19
Dunwei Guo, Chaoyi Wang, Qiang Wang, Zhongpeng Qiao, Hua Tang
OBJECTIVE: Cancer cachexia is often present in patients with advanced malignant tumors, and the subsequent body weight reduction results in poor quality of life. However, there has been no progress in developing effective clinical therapeutic strategies for skeletal muscle wasting in cancer cachexia. Herein, we explored the functions of pantoprazole on cancer cachexia skeletal muscle wasting. METHODS: The mouse colon adenocarcinoma cell line C26 was inoculated in the right forelimb of male BALB/C mice to establish a cancer cachexia model...
April 24, 2017: Oncotarget
https://www.readbyqxmd.com/read/28488836/effects-of-low-load-resistance-exercise-with-blood-flow-restriction-on-intramuscular-hemodynamics-oxygenation-level-and-water-content
#20
Osamu Yanagisawa, Atsuki Fukutani
BACKGROUND: Muscle metabolism during and after low-load blood flow restriction (BFR) exercise should be further investigated to clarify the mechanism by which the exercise leads to muscle hypertrophy, and increases strength and endurance. We aimed to investigate the effects of low-load resistance exercise with BFR on intramuscular hemodynamics, oxygenation level, and water content. METHODS: Seven men performed ankle plantar flexion exercise (120 repetitions, 30% one repetition maximum) using a custom-made device with and without BFR inside a magnetic resonance scanner...
May 9, 2017: Journal of Sports Medicine and Physical Fitness
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