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Jill L Sondeen, Malcolm D Prince, Irene A Polykratis, Orlando Hernandez, Jaime Torres-Mendoza, Rodolfo De Guzman, James K Aden, Michael A Dubick
During the past several years, trauma resuscitation in human patients has evolved from decreased use of crystalloids to increased use of blood products. Of high interest is the role of platelets in trauma resuscitation. Because conducting prehos- pital resuscitation in human trauma patients is very difficult, swine are often the animal model of choice for such studies because their coagulation and hemodynamic systems are similar to those in humans. However, consistent production of sufficient swine platelets for such studies has not previously been achieved...
May 2014: Journal of the American Association for Laboratory Animal Science: JAALAS
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