Shicong Tang, Qing Wang, Ke Sun, Ying Song, Rui Liu, Xin Tan, Huimeng Li, Yafeng Lv, Fuying Yang, Jiawen Zhao, Sijia Li, Pingping Bi, Jiali Yang, Zhengna Zhu, Dong Chen, Zhirui Chuan, Xiaomao Luo, Zaoxiu Hu, Ying Liu, Zhenhui Li, Tengfei Ke, Dewei Jiang, Kai Zheng, Rirong Yang, Kai Chen, Rong Guo
BACKGROUND: Breast cancer (BC) exhibits remarkable heterogeneity. However, the transcriptomic heterogeneity of BC at the single-cell level has not been fully elucidated. METHODS: We acquired BC samples from 14 patients. Single-cell RNA sequencing (scRNA-seq), bioinformatic analyses, along with immunohistochemistry (IHC) and immunofluorescence (IF) assays were carried out. RESULTS: According to the scRNA-seq results, 10 different cell types were identified...
April 5, 2024: Apoptosis: An International Journal on Programmed Cell Death