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https://www.readbyqxmd.com/read/28097678/aberrant-tyrosinase-expression-in-an-atypical-fibroxanthoma-a-case-report
#1
Amy Weiss, Vijay Vanchinathan, Eun Ji Kwon
Atypical fibroxanthoma (AFX) is a histologic mimicker of a variety of spindle cell neoplasms and careful microscopic and immunohistochemical evaluation is critical in establishing the correct diagnosis. Here we report the histologic and immunohistochemical work-up of a 1 cm nodule involving the left dorsal hand of a 66-year-old patient. Light microscopy revealed fascicles of spindled and pleomorphic cells within the dermis demonstrating increased mitotic activity occurring in the background of sun-damaged skin...
January 18, 2017: Journal of Cutaneous Pathology
https://www.readbyqxmd.com/read/28095747/effects-of-roller-massager-on-muscle-recovery-after-exercise-induced-muscle-damage
#2
Nuno Casanova, Joana F Reis, João R Vaz, Rita Machado, Bruno Mendes, Duane C Button, Pedro Pezarat-Correia, Sandro R Freitas
Two experiments (n = 10) were conducted to determine the effects of roller massager (RM) on ankle plantar flexor muscle recovery after exercise-induced muscle damage (EIMD). Experiment 1 examined both functional [i.e., ankle plantar flexion maximal isometric contraction and submaximal (30%) sustained force; ankle dorsiflexion maximal range of motion and resistance to stretch; and medial gastrocnemius pain pressure threshold] and morphological [cross-sectional area, thickness, fascicle length, and fascicle angle] variables, before and immediately, 1, 24, 48, and 72 h after an EIMD stimulus...
January 18, 2017: Journal of Sports Sciences
https://www.readbyqxmd.com/read/28077660/muscle-spindles-in-human-tibialis-anterior-encode-muscle-fascicle-length-changes
#3
James Thomas Day, Leah R Bent, Ingvars Birznieks, Vaughan G Macefield, Andrew G Cresswell
Muscle spindles provide exquisitely sensitive proprioceptive information regarding joint position and movement. Through passively driven length changes in the muscle-tendon unit (MTU), muscle spindles detect joint rotations because of their in-parallel mechanical linkage to muscle fascicles. In human microneurography studies, muscle fascicles are assumed to follow the MTU and, as such, fascicle length is not measured in such studies. However, under certain mechanical conditions compliant structures can act to decouple the fascicles, and therefore the spindles, from the MTU...
January 11, 2017: Journal of Neurophysiology
https://www.readbyqxmd.com/read/28076294/simulation-of-effects-of-the-electrode-structure-and-material-in-the-density-measuring-system-of-the-peripheral-nerve-based-on-micro-electrical-impedance-tomography
#4
Saber Behkami, Javad Frounchi, Firouz Ghaderi Pakdel, Thomas Stieglitz
The electrode structure in micro-electrical impedance tomography (MEIT) highly influences the measurement sensitivity and therefore the reconstructed image quality. Hence, optimizing the electrode structure leads to the improvement of image quality in the reconstruction procedure. Although there have been many investigations on electrical impedance tomography (EIT) electrodes, there is no comprehensive study on their influence on images of the peripheral nerve. In this paper, we present a simulation method to study the effects of the electrode structure in the density measurement system of the peripheral nerve based on MEIT...
January 11, 2017: Biomedizinische Technik. Biomedical Engineering
https://www.readbyqxmd.com/read/28073652/tarsal-tunnel-syndrome-due-to-three-different-types-of-ganglion-during-a-12-year-period-a-case-report
#5
Motohisa Kawakatsu, Toshihiro Ishiko, Masafumi Sumiya
A 52-year-old male complained of numbness and radiating pain affecting the plantar region of his left foot. He was found to have recurrent tarsal tunnel syndrome due to posterior tibial nerve compression by 3 different types of ganglion during a 12-year period. To the best of our knowledge, a similar case has not been documented. At the first operation, flexor retinaculum release and simple excision of an epineural ganglion were performed without injuring the nerve fascicles; however, an intrafascicular ganglion developed approximately 2 years later...
January 7, 2017: Journal of Foot and Ankle Surgery: Official Publication of the American College of Foot and Ankle Surgeons
https://www.readbyqxmd.com/read/28071819/evidence-that-interfibrillar-load-transfer-in-tendon-is-supported-by-small-diameter-fibrils-and-not-extrafibrillar-tissue-components
#6
Spencer E Szczesny, Kristen L Fetchko, George R Dodge, Dawn M Elliott
Collagen fibrils in tendon are believed to be discontinuous and transfer tensile loads through shear forces generated during interfibrillar sliding. However, the structures that transmit these interfibrillar forces are unknown. Various extrafibrillar tissue components (e.g., glycosaminoglycans, collagens XII and XIV) have been suggested to transmit interfibrillar loads by bridging collagen fibrils. Alternatively, collagen fibrils may interact directly through physical fusions and interfibrillar branching. The objective of this study was to test whether extrafibrillar proteins are necessary to transmit load between collagen fibrils or if interfibrillar load transfer is accomplished directly by the fibrils themselves...
January 10, 2017: Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society
https://www.readbyqxmd.com/read/28067672/evolution-of-fibroblastic-connective-tissue-nevus-in-an-infant
#7
Michael C Lynch, Thomas D Samson, Andrea L Zaenglein, Catherine G Chung
Fibroblastic connective tissue nevus (FCTN) is a rare and recently described neoplasm of fibroblastic/myofibroblastic lineage. We report a case of a 1-month-old healthy male infant who presented with a dermal plaque on the upper chest since birth. A punch biopsy demonstrated a dermal spindle-cell neoplasm with variable smooth muscle actin positivity and negative staining for CD34, consistent with myofibroma. Over the course of the next year, the remaining lesional tissue exhibited clinical softening and a surgical excisional specimen revealed histologic findings distinct from the original biopsy...
January 5, 2017: American Journal of Dermatopathology
https://www.readbyqxmd.com/read/28063610/ultrasound-measurements-of-skeletal-muscle-architecture-are-associated-with-strength-and-functional-capacity-in-older-adults
#8
Isaac Selva Raj, Stephen R Bird, Anthony J Shield
The goal of this study was to determine whether ultrasound measures of muscle architecture can be used to infer strength and functional capacity in older adults. Thirty-six healthy older adults (aged 68.2 ± 5.3 y) undertook isokinetic dynamometry for isometric and isokinetic concentric knee extensor strength, the 6-m fast walk, timed up and go, stair climb and descent and vertical jump tests. Longitudinal brightness-mode ultrasound scans (probe frequency, 10 MHz) of the vastus lateralis, vastus intermedius, rectus femoris and gastrocnemius medialis were obtained, and muscle architecture measures (thickness, fascicle pennation angle and fascicle length) were correlated with the aforementioned strength and functional measures...
January 4, 2017: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/28063145/solitary-fibrous-tumor-of-the-lung-a-case-report
#9
Yoshinobu Ichiki, Keisei Kakizoe, Takayuki Hamatsu, Atsuji Matsuyama, Taketoshi Suehiro, Fumihiro Tanaka, Masanori Hisaoka, Keizo Sugimachi
Solitary fibrous tumors (SFTs) are relatively rare neoplasms that commonly occur in the pleura. The pathological feature of SFTs is a proliferation of spindle-shaped cells in interlacing or storiform fascicles. SFTs appear to derived from pluripotential submesothelial cells, but not the covering mesothelium. SFTs distinctively show diffuse staining for CD34 but lack staining for smooth muscle markers. We herein report a relatively rare case of a 68-year-old male patient without symptoms, who underwent resection for what was considered to be SFT...
December 2017: Surgical Case Reports
https://www.readbyqxmd.com/read/28060689/-schwannoma-of-the-upper-extremity-retrospective-analysis-of-17-cases
#10
Ângelo Sá, Leandro Nobre Azevedo, Luísa Cunha
INTRODUCTION: Schwannoma or neurilemmoma is a benign peripheric nerve tumor that usually presents as a slow growing single lesion; it has origin in Schwann cells proliferation. Although it represents a small percentage of the benign tumors of the upper arm, it is the most frequent of neural origin. We present a retrospective study of upper limb schwannomas; our aim is establish the appropriate preoperative approach, to recognise the efficiency of the treatment and the pos-operative follow-up...
September 2016: Acta Médica Portuguesa
https://www.readbyqxmd.com/read/28059097/fibrous-hamartoma-of-infancy-a-clinicopathologic-study-of-145-cases-including-2-with-sarcomatous-features
#11
Alyaa Al-Ibraheemi, Anthony Martinez, Sharon W Weiss, Harry P Kozakewich, Antonio R Perez-Atayde, Henry Tran, David M Parham, William R Sukov, Karen J Fritchie, Andrew L Folpe
Fibrous hamartoma of infancy is a rare soft tissue lesion of infants and young children with characteristic triphasic morphology, which typically occurs in the axilla and less commonly in other locations. We reviewed 145 cases of fibrous hamartoma of infancy from our consultation archives. Cases occurred in 106 males and 39 females (mean age-15 months; range-birth to 14 years), and involved both typical sites (eg, axilla/back/upper arm) (n=69) and unusual locations (n=76). Six were congenital. The tumors presented as subcutaneous masses and ranged from 0...
January 6, 2017: Modern Pathology: An Official Journal of the United States and Canadian Academy of Pathology, Inc
https://www.readbyqxmd.com/read/28057689/comparative-inflorescence-development-in-selected-andean-santalales
#12
Vanessa Suaza-Gaviria, Favio González, Natalia Pabón-Mora
PREMISE OF THE STUDY: Loranthaceae, Santalaceae, and Viscaceae are the most diversified hemiparasitic families of Santalales in the Andes. Their partial inflorescences (PIs) vary from solitary flowers, or dichasia in most Santalales, to congested floral groups along articles in most Viscaceae. The atypical articled inflorescences in Phoradendreae (Viscaceae), a phylogenetic novelty restricted to this tribe, have been variously described as racemes, spikes, fascicles, or as intercalary inflorescences, but no developmental studies have been performed to compare them with the construction of PIs across Santalales...
January 5, 2017: American Journal of Botany
https://www.readbyqxmd.com/read/28049266/does-vitamin-d-affect-muscle-strength-and-architecture-an-isokinetic-and-ultrasonographic-study
#13
Murat Kara, Timur Ekiz, Özgür Kara, Tülay Tiftik, Fevziye Ünsal Malas, Sibel Özbudak Demir, Neşe Özgirgin
BACKGROUND AND OBJECTIVES: The objective of this study was to explore the association between 25- hydroxyvitamin D (25(OH)D) and muscle strength/architecture. METHODS AND STUDY DESIGN: Thirty patients (27 women, 3 men) were allocated into Group I (n=15, mean age; 44.4±9.4 years) and Group II (n=15, mean age; 39.0±9.9 years) according to the median of 25(OH)D (<13.7 ng/mL vs >13.7 ng/mL, respectively). Peak torque/body weight of the knee flexor/extensor muscles at 60°/sec and 180°/sec and those of ankle flexor/ extensor muscles at 30°/sec and 90°/sec were evaluated by using a Biodex System 3 Pro Multijoint System isokinetic dynamometer...
January 2017: Asia Pacific Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28044199/muscle-fascicle-shortening-behaviour-of-vastus-lateralis-during-a-maximal-force-velocity-test
#14
Hugo Hauraix, Sylvain Dorel, Giuseppe Rabita, Gaël Guilhem, Antoine Nordez
PURPOSE: Muscle fascicles-tendon interactions are the main determinant in production of high joint velocity. Currently, no study has investigated the muscle fascicles behaviour of knee extensor muscles until the highest reachable velocity (e.g., unloaded knee extension). We aimed to track the changes in vastus lateralis fascicles length during knee extensions to quantify muscle fascicles and tendinous tissues contributions to muscle-tendon unit shortening and to determine maximal muscle fascicles shortening velocity...
January 3, 2017: European Journal of Applied Physiology
https://www.readbyqxmd.com/read/28035702/refinements-of-nerve-repair-with-connector-assisted-coaptation
#15
REVIEW
Ivica Ducic, Bauback Safa, Erick DeVinney
Peripheral nerve repair can be very rewarding for both surgeon and patient when expected outcomes are achieved. In many cases, however, the results are suboptimal due to number of possible objective and technical reasons. Although we cannot influence patent's comorbidities, the extent or mechanism of the nerve injury, we may help optimize technical details when aiming towards improved outcomes. While the suture coaptation for primary nerve repair or nerve reconstruction with grafting served as the reconstructive standard for many decades, technical imperfections remain threats to reconstructive goals...
December 30, 2016: Microsurgery
https://www.readbyqxmd.com/read/28028870/neuromuscular-performance-of-maximal-voluntary-explosive-concentric-contractions-is-influenced-by-angular-acceleration
#16
D Hahn, P Bakenecker, F Zinke
Torque production during maximal voluntary explosive contractions is considered to be a functionally more relevant neuromuscular measure than steady-state torque, but little is known about accelerated concentric contractions. This study investigated torque, muscle activity, and fascicle behavior during isometric and fast concentric contractions of quadriceps femoris. Ten participants performed maximal voluntary explosive isometric, isovelocity, and additional concentric knee extensions at angular accelerations ranging from 700 to 4000° s(-2) that resulted in an angular velocity of 300° s(-1) at 40° knee flexion...
December 28, 2016: Scandinavian Journal of Medicine & Science in Sports
https://www.readbyqxmd.com/read/28009608/fosb-is-a-useful-diagnostic-marker-for-pseudomyogenic-hemangioendothelioma
#17
Yin P Hung, Christopher D M Fletcher, Jason L Hornick
Pseudomyogenic (epithelioid sarcoma-like) hemangioendothelioma is a distinctive vascular neoplasm of intermediate biological potential with a predilection for young adults and frequent multifocal presentation. Pseudomyogenic hemangioendothelioma is characterized by loose fascicles of plump spindled and epithelioid cells with abundant eosinophilic cytoplasm and coexpression of keratins and endothelial markers. Recently, a SERPINE1-FOSB fusion has been identified as a consistent genetic alteration in pseudomyogenic hemangioendothelioma...
December 22, 2016: American Journal of Surgical Pathology
https://www.readbyqxmd.com/read/28006854/quantification-of-human-upper-extremity-nerves-and-fascicular-anatomy
#18
Natalie A Brill, Dustin J Tyler
INTRODUCTION: This paper provides detailed quantification of upper extremity nerve and fascicular anatomy. The purpose is to provide values and trends in neural features useful for clinical applications and neural interface device design. METHODS: Nerve cross sections were taken from 4 ulnar, 4 median, and 3 radial nerves from 5 arms of 3 human cadavers. Quantified nerve features included cross sectional area, minor diameter, and major diameter. Fascicular features analyzed included count, perimeter, area, and position...
December 22, 2016: Muscle & Nerve
https://www.readbyqxmd.com/read/28005643/fibromatosis-associated-with-neuromuscular-choristoma-evaluation-by-fdg-pet-ct
#19
Stephen M Broski, Benjamin M Howe, Robert J Spinner, Kimberly K Amrami
Neuromuscular choristoma (NMC) is a rare benign peripheral nerve lesion consisting of mature skeletal muscle fibers admixed with nerve fascicles. Aggressive fibromatosis frequently develops in association with NMC, often after surgery or biopsy, but the exact pathogenesis is not known. We present a case of NMC complicated by aggressive fibromatosis evaluated by F-FDG PET/CT and examine the relationship of metabolic activity and MRI signal characteristics.
December 21, 2016: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/28004174/altered-patterns-of-displacement-within-the-achilles-tendon-following-surgical-repair
#20
Åsa Fröberg, Ann-Sophie Cissé, Matilda Larsson, Mattias Mårtensson, Michael Peolsson, Tomas Movin, Anton Arndt
PURPOSE: Ultrasound speckle tracking was used to compare tendon deformation patterns between uninjured and surgically repaired Achilles tendons at 14-27-month follow-up. The hypothesis was that the non-homogenous displacement pattern previously described in uninjured tendons, where displacement within deep layers of the tendons exceeds that of superficial layers, is altered following tendon rupture and subsequent surgical repair. METHODS: In the first part of this study, an in-house-developed block-matching speckle tracking algorithm was evaluated for assessment of displacement on porcine flexor digitorum tendons...
December 21, 2016: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
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