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https://www.readbyqxmd.com/read/29139316/association-of-gastrocnemius-muscle-stiffness-with-passive-ankle-joint-stiffness-and-sex-related-difference-in-the-joint-stiffness
#1
Kintaro Chino, Hideyuki Takashi
Passive ankle joint stiffness is affected by all structures located within and over the joint, and is greater in men than in women. Localized muscle stiffness can be assessed by ultrasound shear wave elastography, and muscle architecture such as fascicle length and pennation angle can be measured by B-mode ultrasonography. Thus, we assessed localized muscle stiffness of the medial gastrocnemius (MG) with consideration of individual variability in the muscle architecture, and examined the association of the muscle stiffness with passive ankle joint stiffness and the sex-related difference in the joint stiffness...
November 15, 2017: Journal of Applied Biomechanics
https://www.readbyqxmd.com/read/29118191/effects-of-muscle-action-type-on-corticospinal-excitability-and-triceps-surae-muscle-tendon-mechanics
#2
Pedro Valadao, Sadao Kurokawa, Taija Finni, Janne Avela
This study investigated if the specific motor control strategy reported for eccentric muscle actions is dependent of muscle mechanical behavior. Motor-evoked potentials (MEP), Hoffman reflex (H-reflex), fascicle length (FL), pennation angle (PA) and fascicle velocity (FV) of soleus (SOL) muscle were compared between isometric and two eccentric conditions. Ten volunteers performed maximal plantarflexion trials in isometric, slow eccentric (25º/s) and fast eccentric (100º/s) conditions, each on a different randomized testing session...
November 8, 2017: Journal of Neurophysiology
https://www.readbyqxmd.com/read/29116573/an-evidence-based-framework-for-strengthening-exercises-to-prevent-hamstring-injury
#3
REVIEW
Matthew N Bourne, Ryan G Timmins, David A Opar, Tania Pizzari, Joshua D Ruddy, Casey Sims, Morgan D Williams, Anthony J Shield
Strength training is a valuable component of hamstring strain injury prevention programmes; however, in recent years a significant body of work has emerged to suggest that the acute responses and chronic adaptations to training with different exercises are heterogeneous. Unfortunately, these research findings do not appear to have uniformly influenced clinical guidelines for exercise selection in hamstring injury prevention or rehabilitation programmes. The purpose of this review was to provide the practitioner with an evidence-base from which to prescribe strengthening exercises to mitigate the risk of hamstring injury...
November 7, 2017: Sports Medicine
https://www.readbyqxmd.com/read/29107592/generation-of-a-motor-nerve-organoid-with-human-stem-cell-derived-neurons
#4
Jiro Kawada, Shohei Kaneda, Takaaki Kirihara, Asif Maroof, Timothée Levi, Kevin Eggan, Teruo Fujii, Yoshiho Ikeuchi
During development, axons spontaneously assemble into a fascicle to form nerves and tracts in the nervous system as they extend within a spatially constrained path. However, understanding of the axonal fascicle has been hampered by lack of an in vitro model system. Here, we report generation of a nerve organoid composed of a robust fascicle of axons extended from a spheroid of human stem cell-derived motor neurons within our custom-designed microdevice. The device is equipped with a narrow channel providing a microenvironment that facilitates the growing axons to spontaneously assemble into a unidirectional fascicle...
November 14, 2017: Stem Cell Reports
https://www.readbyqxmd.com/read/29104116/putative-roles-of-soluble-trophic-factors-in-facial-nerve-regeneration-target-reinnervation-and-recovery-of-vibrissal-whisking
#5
REVIEW
Habib Bendella, Svenja Rink, Maria Grosheva, Levent Sarikcioglu, Tessa Gordon, Doychin N Angelov
It is well-known that, after nerve transection and surgical repair, misdirected regrowth of regenerating motor axons may occur in three ways. The first way is that the axons enter into endoneurial tubes that they did not previously occupy, regenerate through incorrect fascicles and reinnervate muscles that they did not formerly supply. Consequently the activation of these muscles results in inappropriate movements. The second way is that, in contrast with the precise target-directed pathfinding by elongating motor nerves during embryonic development, several axons rather than a single axon grow out from each transected nerve fiber...
November 8, 2017: Experimental Neurology
https://www.readbyqxmd.com/read/29104072/immediate-elimination-of-injured-white-matter-tissue-achieves-a-rapid-axonal-growth-across-the-severed-spinal-cord-in-adult-rats
#6
Takeshi Nishio, Hiroshi Fujiwara, Isaku Kanno
In general, axonal regeneration is very limited after transection of adult rat spinal cord. We previously demonstrated that regenerative axons reached the lesion site within 6hours of sharp transection with a thin scalpel. However, they failed to grow across the lesion site, where injured axon fragments (axon-glial complex, AGC) were accumulated. Considering a possible role of these axon fragments as physicochemical barriers, we examined the effects of prompt elimination of the barriers on axonal growth beyond the lesion site...
November 2, 2017: Neuroscience Research
https://www.readbyqxmd.com/read/29081586/histological-and-functional-characterizations-of-the-digital-cushion-in-quarter-horses
#7
Babak Faramarzi, Linnea Lantz, Dongbin Lee, Wael Khamas
The digital cushion (DC) plays a role in absorbing and dampening forces applied to the foot and therefore supports internal structures such as navicular bone; yet, its architecture is not well-known. The goal of this study was to characterize the microanatomical structure of the DC in horses with clinically sound hooves. Both forefeet from the cadavers of 12 adult Quarter horses were cut and sectioned and samples of the following 4 regions of the DC were obtained: axial proximal (AxProx), axial distal (AxDis), abaxial lateral (AbxLat), and abaxial medial (AbxMed)...
October 2017: Canadian Journal of Veterinary Research, Revue Canadienne de Recherche Vétérinaire
https://www.readbyqxmd.com/read/29070765/morphometric-analysis-of-growing-tenocytes-in-the-superficial-digital-flexor-tendon-of-piglets
#8
Naoki Takahashi, Prasarn Tangkawattana, Yoshiki Ootomo, Takuya Hirose, Jun Minaguchi, Hiromi Ueda, Michi Yamada, Kazushige Takehana
The fine structures of different tendons in various animals at different ages have been studied extensively to reveal their arrangement and growth patterns. However, knowledge of the microstructures of the growing tenocytes in the tendons of piglets is still lacking. Thus, we performed the first morphometric analysis to describe the characteristics of tenocytes in the metacarpal superficial digital flexor tendon of 0-, 10-, and 20-day-old piglets. In the present study, hydrochloric acid/collagenase digestion was applied to remove the interstitial connective tissue and obtain clear visualization of intact tenocytes and their cytoplasmic processes (Cp)...
October 25, 2017: Journal of Veterinary Medical Science
https://www.readbyqxmd.com/read/29068534/freezing-does-not-alter-multiscale-tendon-mechanics-and-damage-mechanisms-in-tension
#9
Andrea H Lee, Dawn M Elliott
It is common in biomechanics to use previously frozen tissues, where it is assumed that the freeze-thaw process does not cause consequential mechanical or structural changes. We have recently quantified multiscale tendon mechanics and damage mechanisms using previously frozen tissue, where damage was defined as an irreversible change in the microstructure that alters the macroscopic mechanical parameters. Because freezing has been shown to alter tendon microstructures, the objective of this study was to determine if freezing alters tendon multiscale mechanics and damage mechanisms...
October 25, 2017: Annals of the New York Academy of Sciences
https://www.readbyqxmd.com/read/29067911/syncope-in-a-young-man-role-of-purkinje-fibres-in-idiopathic-ventricular-fibrillation
#10
Claire A Martin, Laurence Nunn, Pier D Lambiase
A young man suffered cardiac arrests with polymorphic ventricular tachycardia (PVT) and ventricular fibrillation (VF) triggered by ventricular premature contractions (PVCs). The arrhythmia was resistant to anti-arrhythmics, so after ICD implantation he underwent successful ablation of the triggering VE beat, which was pace-mapped to the left posterior hemi-fascicle. We review the evidence for the role of the Purkinje network in the initiation and maintenance of PVT and VF, postulating a channelopathy as a possible underlying cause, and provide recommendations for PVC ablation...
July 2017: Indian Pacing and Electrophysiology Journal
https://www.readbyqxmd.com/read/29050821/chiral-behavior-in-rat-tail-tendon-fascicles
#11
Kimberly A Buchanan, Roderic S Lakes, Ray Vanderby
Ex vivo tendon mechanical behavior has been well described under rotationally constrained uniaxial tensile testing. During standard loading of rat tail tendon (RTT) fascicles, apparent axial twist has been observed. To quantify this behavior, we designed a custom testing setup, utilizing magnetic suspension, to allow unconstrained axial rotation during tensile loading. We characterized the rotational behavior of single and paired RTT fascicles under cyclic loading. We also measured stress relaxation across loading cycles as well as "rotational relaxation"...
October 7, 2017: Journal of Biomechanics
https://www.readbyqxmd.com/read/29049892/velocity-of-the-muscle-tendon-unit-is-sex-dependent-and-not-altered-with-acute-static-stretch
#12
Carey L Simpson, Rowan R Smart, Dylan Ee Melady, Jennifer M Jakobi
Contraction velocity of a muscle tendon unit (MTU) is dependent upon the interrelationship between fascicles shortening and the tendon lengthening. Altering the mechanical properties of these tissues through a perturbation such as static stretching slows force generation. Females, who have inherently greater compliance compared with males have slower velocity of MTU components. The addition of a static stretch might further exacerbate this sex difference. The purpose of this study was to investigate the velocity of fascicle shortening and tendon lengthening in males and females during isometric maximal voluntary contraction (MVC) of the plantar flexors prior to and following an acute static stretch...
October 19, 2017: Applied Physiology, Nutrition, and Metabolism, Physiologie Appliquée, Nutrition et Métabolisme
https://www.readbyqxmd.com/read/29046788/a-rare-case-of-dedifferentiated-liposarcoma-of-the-sinonasal-cavity-a-case-report
#13
Masaru Miyazaki, Mikiko Aoki, Satoru Oba, Toshifumi Sakata, Takashi Nakagawa, Kazuki Nabeshima
Sarcoma is an uncommon histopathological presentation of sinonasal tumors, comprising ~15% of all cases; liposarcoma is particularly uncommon. An analysis of the available medical literature revealed no prior reports of dedifferentiated liposarcoma (DDLPS) of the sinonasal cavity. This case report presents a rare case of DDLPS of the sinonasal cavity. A 40-year old six-week pregnant female was admitted with a left nasal obstruction. Endoscopic evaluation of the left nasal cavity revealed a polypoid lesion. A computed tomography scan indicated a mass invading the left nasal cavity, maxillary sinus and anterior ethmoid sinus with focal destruction of the surrounding bone...
October 2017: Molecular and Clinical Oncology
https://www.readbyqxmd.com/read/29042331/the-first-experience-of-triple-nerve-transfer-in-proximal-radial-nerve-palsy
#14
Mohammadreza Emamhadi, Sasan Andalib
BACKGROUND: Injury to distal of posterior cord of brachial plexus leads to palsy of the radial and axillary nerves. The symptoms are usually motor deficits of the deltoid muscle, triceps brachii muscle, and the extensor muscles of the wrist, thumb and fingers. Tendon transfers, nerve grafts, and nerve transfers are options of surgical treatment of proximal radial nerve palsy to restore some motor functions. Tendon transfer is painful, requires a long immobilization, and decreases donor muscle strength; nevertheless, nerve transfer produces promising outcome...
October 14, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/29031739/neural-correlates-of-visuospatial-bias-in-patients-with-left-hemisphere-stroke-a-causal-functional-contribution-analysis-based-on-game-theory
#15
C Malherbe, R M Umarova, M Zavaglia, C P Kaller, L Beume, G Thomalla, C Weiller, C C Hilgetag
Stroke patients frequently display spatial neglect, an inability to report, or respond to, relevant stimuli in the contralesional space. Although this syndrome is widely considered to result from the dysfunction of a large-scale attention network, the individual contributions of damaged grey and white matter regions to neglect are still being disputed. Moreover, while the neuroanatomy of neglect in right hemispheric lesions is well studied, the contributions of left hemispheric brain regions to visuospatial processing are less well understood...
October 12, 2017: Neuropsychologia
https://www.readbyqxmd.com/read/29030643/three-dimensional-myoarchitecture-of-the-lower-esophageal-sphincter-and-esophageal-hiatus-using-optical-sectioning-microscopy
#16
Ali Zifan, Dushyant Kumar, Leo K Cheng, Ravinder K Mittal
Studies to date have failed to reveal the anatomical counterpart of the lower esophageal sphincter (LES). We assessed the LES and esophageal hiatus morphology using a block containing the human LES and crural diaphragm, serially sectioned at 50 μm intervals and imaged at 8.2 μm/pixel resolution. A 3D reconstruction of the tissue block was reconstructed in which each of the 652 cross sectional images were also segmented to identify the boundaries of longitudinal (LM) and circular muscle (CM) layers. The CM fascicles on the ventral surface of LES are arranged in a helical/spiral fashion...
October 13, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29027683/ultrasonographic-measurement-of-the-biceps-femoris-long-head-muscle-architecture
#17
Sandro R Freitas, João Marmeleira, Maria João Valamatos, Anthony Blazevich, Pedro Mil-Homens
OBJECTIVES: Biceps femoris long-head architectural assessment using ultrasonography (US) has not been previously described in detail for both acquisition (image capture) and digitization (image measurement) processes, and the effect of the US window width is unknown. This study aimed to describe the reliability and test-retest minimum detectable difference of US-based biceps femoris architectural measurements. METHODS: Muscle length was determined by marking the muscle-tendon junction distances...
October 13, 2017: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
https://www.readbyqxmd.com/read/29026362/inflammatory-myofibroblastic-tumor-of-the-breast-mimicking-malignancy-in-an-elderly-male
#18
Fouzia Siraj, Manveen Kaur, Varsha Dalal, Jain Sonam
BACKGROUND: Inflammatory myofibroblastic tumor (IMT) is a rare, distinctive lesion composed of a proliferation of myofibroblastic spindle cells accompanied by an inflammatory infiltrate. It was first described in the lung, but its occurrence at various extrapulmonary sites has also been reported. The literature mentions only a handful of cases of IMT in the breast and only 1 case in the male breast. We report the second case of IMT in the male breast. CASE REPORT: A 60-year-old male presented with a large, lobulated lump in the left breast that had progressively increased in size during the past year...
2017: Ochsner Journal
https://www.readbyqxmd.com/read/29023914/melanocytic-naevi-with-perineurial-differentiation-a-distinctive-variant-of-neurotised-naevi-and-a-diagnostic-pitfall-with-desmoplastic-melanoma
#19
Ingrid Ferreira, Peter Kind, Ivo Van Den Berghe, Lucy Melly, Felix Offner, Jason L Hornick, Thomas Brenn
AIMS: Spindle cell differentiation is not an uncommon finding in common acquired naevi and may represent a form of neurotisation with Schwannian differentiation of melanocytes. Perineurial differentiation in this context appears to be distinctly rare and is only poorly documented in the literature. METHODS AND RESULTS: We have identified six melanocytic tumours showing spindle cell morphology and perineurial differentiation from routine and referral material. Clinical data and follow-up were obtained, and the histological and immunohistochemical features were analysed...
October 11, 2017: Histopathology
https://www.readbyqxmd.com/read/29018508/gait-improvements-after-peroneal-or-tibial-nerve-transfer-in-patients-with-foot-drop-a-retrospective-study
#20
Rahul K Nath, Chandra Somasundaram
Background: Injury to the common peroneal nerve disrupts the motor control pathway to ankle dorsiflexors and evertors, as well as toe extensors, resulting in pathological gait and foot drop. Direct external compression on the fibular head is the most frequent cause of peroneal nerve impairment and has poor prognosis. Methods and Patients: Here, we report the surgical outcome of 21 patients with foot drop (9 males and 12 females) who underwent nerve transfer procedure of either the superficial peroneal nerve or the tibial nerve fascicles to the motor branch of the tibialis anterior and to the deep peroneal nerve...
2017: Eplasty
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