keyword
MENU ▼
Read by QxMD icon Read
search

Endocrine disruption chemical

keyword
https://www.readbyqxmd.com/read/28341988/unexpected-differences-between-planar-and-column-liquid-chromatographic-retention-of-1-acenaphthenol-enantiomers-controlled-by-supramolecular-interactions-involving-%C3%AE-cyclodextrin-at-subambient-temperatures
#1
Hatsuichi Ohta, Elżbieta Włodarczyk, Krzysztof Piaskowski, Aleksandra Kaleniecka, Lucyna Lewandowska, Michał J Baran, Mariusz Wojnicz, Kiyokatsu Jinno, Yoshihiro Saito, Paweł K Zarzycki
We report the results of experimental work focusing on host-guest supramolecular complex creation between macrocyclic compound (β-cyclodextrin) and 1-acenaphthenol enantiomers (racemic mixture) in liquid phase composed of 35% acetonitrile in water (v/v) at different temperatures ranging from 0 to 90 °C. Experimental setup involved several analytical protocols based on classical non-forced flow planar chromatography (RP-18 TLC plates), micro-TLC (RP-18 W HPTLC plates), column chromatography (HPLC with C-18 and C-30 stationary phases), as well as UV-Vis spectrophotometry and optical microscopy...
March 24, 2017: Analytical and Bioanalytical Chemistry
https://www.readbyqxmd.com/read/28341464/reproductive-effects-of-oestrogenic-endocrine-disrupting-chemicals-in-astyanax-rivularis-inhabiting-headwaters-of-the-velhas-river-brazil
#2
André Alberto Weber, Davidson Peruci Moreira, Rafael Magno Costa Melo, Augusto Bicalho Cruz Vieira, Paula Suzanna Prado, Mirra Angelina Neres da Silva, Nilo Bazzoli, Elizete Rizzo
The Velhas River is the most polluted river in the state of Minas Gerais, south-eastern Brazil. Due to its historical and environmental relevance, the aim of this study was to evaluate the effects of oestrogenic endocrine disruptors on the reproduction of the lambari Astyanax rivularis, a small-sized species found in headwaters of the São Francisco River basin. Quarterly field samplings were carried out during a reproductive cycle in three streams of the upper Velhas River: S1 (reference site) and S2 and S3 (sites contaminated by untreated sewage)...
March 21, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28340460/interactions-between-three-typical-endocrine-disrupting-chemicals-edcs-in-binary-mixtures-exposure-on-myocardial-differentiation-of-mouse-embryonic-stem-cell
#3
Ren Zhou, Wei Cheng, Yan Feng, Hongying Wei, Fan Liang, Yan Wang
In recent years, various kinds of endocrine-disrupting chemicals (EDCs) have been detected in human blood and urine. Thus, it was important to investigate the combined toxicity effect of EDCs. In the present study, we evaluated the individual and combined developmental toxicities of three classic EDCs: perfluorooctane sulfonate (PFOS), perfluorooctanoic acid (PFOA), and bisphenol A (BPA) by embryonic stem cell test (EST). The similarities and differences between combination of same chemical group as well as different chemical groups were investigated in this research...
March 16, 2017: Chemosphere
https://www.readbyqxmd.com/read/28329833/thy1-cd90-expression-is-reduced-by-the-environmental-chemical-tetrabromobisphenol-a-to-promote-adipogenesis-through-induction-of-microrna-103
#4
Collynn F Woeller, E'Lissa Flores, Stephen J Pollock, Richard P Phipps
Environmental chemicals termed "obesogens" disrupt the endocrine system to promote adipogenesis and obesity. Tetrabromobisphenol-A (TBBPA) has been reported to increase adipogenesis, however, the mechanism(s) of action are unclear. Thy1 (CD90) is a glycophosphatidylinositol (GPI) -anchored membrane protein that serves as a marker for stem cells and also plays an important role in regulating adipogenesis and obesity. We investigated whether or not TBBPA promotes adipogenesis in human and mouse cells by reducing Thy1 levels...
February 22, 2017: Toxicological Sciences: An Official Journal of the Society of Toxicology
https://www.readbyqxmd.com/read/28327540/endocrine-disrupting-chemicals-and-endometrial-cancer-an-overview-of-recent-laboratory-evidence-and-epidemiological-studies
#5
REVIEW
Maddalena Mallozzi, Chiara Leone, Francesca Manurita, Filippo Bellati, Donatella Caserta
Background: Although exposure to endocrine disruptor compounds (EDCs) has been suggested as a contributing factor to a range of women's health disorders including infertility, polycystic ovaries and the early onset of puberty, considerable challenges remain in attributing cause and effect on gynaecological cancer. Until recently, there were relatively few epidemiological studies examining the relationship between EDCs and endometrial cancer, however, in the last years the number of these studies has increased...
March 22, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28325592/intersexuality-in-aquatic-invertebrates-prevalence-and-causes
#6
REVIEW
Tiago F Grilo, Rui Rosa
This review is the first assembling information on intersexuality in aquatic invertebrates, from freshwater to estuarine and marine environments. Intersex is a condition whereby an individual of a gonochorist (separate sexes) species has oocytes or distinct stages of spermatogonia, at varying degrees of development, within the normal gonad of the opposite gender (i.e. spermatocytes in the ovary or oocytes in the testis), often involving alterations in the gonadal structure, reproductive tract or external genitalia...
March 18, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28324061/progesterone-protects-against-bpa-induced-arrhythmias-in-female-rat-cardiac-myocytes-via-rapid-signaling
#7
Jianyong Ma, Kui Hong, Hong-Sheng Wang
Bisphenol A (BPA) is an estrogenic endocrine disrupting chemical (EDC) that has a range of potential adverse health effects. Previously we showed that acute exposure to BPA promoted arrhythmias in female rat hearts through estrogen receptor rapid signaling. Progesterone (P4) and estrogen have antagonistic or complementary actions in a number of tissues and systems. In the current study, we examined the influence, and possible protective effect, of P4 on the rapid cardiac actions of BPA in female rat cardiac myocytes...
January 25, 2017: Endocrinology
https://www.readbyqxmd.com/read/28319747/integration-of-in-silico-methods-and-computational-systems-biology-to-explore-endocrine-disrupting-chemical-binding-with-nuclear-hormone-receptors
#8
P Ruiz, A Sack, M Wampole, S Bobst, M Vracko
Thousands of potential endocrine-disrupting chemicals present difficult regulatory challenges. Endocrine-disrupting chemicals can interfere with several nuclear hormone receptors associated with a variety of adverse health effects. The U.S. Environmental Protection Agency (U.S. EPA) has released its reviews of Tier 1 screening assay results for a set of pesticides in the Endocrine Disruptor Screening Program (EDSP), and recently, the Collaborative Estrogen Receptor Activity Prediction Project (CERAPP) data...
March 9, 2017: Chemosphere
https://www.readbyqxmd.com/read/28318786/modulation-of-the-stress-response-in-wild-fish-is-associated-with-variation-in-dissolved-nitrate-and-nitrite
#9
Tom G Pottinger
Disruption of non-reproductive endocrine systems in wildlife by chemicals has received little attention but represents a potentially significant problem. Nitrate is a major anthropogenic contaminant in the freshwater aquatic environment and has been identified as a potential disrupter of endocrine function in aquatic animals. This study was conducted to investigate the relationship between the function of the neuroendocrine stress axis in fish and inorganic N loading along reaches of rivers receiving cumulative point source and diffuse chemical inputs...
March 15, 2017: Environmental Pollution
https://www.readbyqxmd.com/read/28300666/curcumin-attenuates-bpa-induced-insulin-resistance-in-hepg2-cells-through-suppression-of-jnk-p38-pathways
#10
Shanshan Geng, Shijia Wang, Weiwei Zhu, Chunfeng Xie, Xiaoting Li, Jieshu Wu, Jianyun Zhu, Ye Jiang, Xue Yang, Yuan Li, Yue Chen, Xiaoqian Wang, Yu Meng, Mingming Zhu, Rui Wu, Cong Huang, Caiyun Zhong
Bisphenol A (BPA) is an artificial environmental endocrine disrupting chemicals. Accumulating evidence indicates that exposure to BPA contributes to insulin resistance through diverse mechanism including inflammation and oxidative stress. Previous studies have suggested curcumin as a safe phytochemical which can improve obesity-related insulin resistance, inflammation and oxidative stress. The present study aimed to investigate the ability of curcumin to prevent BPA-induced insulin resistance in vitro and the underlying mechanism...
March 11, 2017: Toxicology Letters
https://www.readbyqxmd.com/read/28298639/benzyl-butyl-phthalate-decreases-myogenic-differentiation-of-endometrial-mesenchymal-stem-stromal-cells-through-mir-137-mediated-regulation-of-pitx2
#11
Hung-Sheng Chen, Chia-Yi Hsu, Yu-Chia Chang, Hui-Yu Chuang, Cheng-Yu Long, Tsung-Hua Hsieh, Eing-Mei Tsai
Phthalate, an environmental toxin, has been considered as an endocrine-disrupting chemical. Growing evidence has demonstrated links between endocrine-disrupting chemicals, tissue development, and reproductive physiology, but the mechanisms of gene expression regulation by environmental factors that affect cell differentiation are unclear. Herein, we investigated the effects of butyl benzyl phthalate (BBP) on human endometrial mesenchymal stem/stromal cell (EN-MSC) differentiation and identified a novel signaling pathway...
March 15, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28292651/human-exposure-to-endocrine-disrupting-chemicals-effects-on-the-male-and-female-reproductive-systems
#12
REVIEW
Stavros Sifakis, Vasilis P Androutsopoulos, Aristeidis M Tsatsakis, Demetrios A Spandidos
Endocrine disrupting chemicals (EDCs) comprise a group of chemical compounds that have been examined extensively due to the potential harmful effects in the health of human populations. During the past decades, particular focus has been given to the harmful effects of EDCs to the reproductive system. The estimation of human exposure to EDCs can be broadly categorized into occupational and environmental exposure, and has been a major challenge due to the structural diversity of the chemicals that are derived by many different sources at doses below the limit of detection used by conventional methodologies...
March 6, 2017: Environmental Toxicology and Pharmacology
https://www.readbyqxmd.com/read/28288144/thyroid-stimulating-hormone-levels-in-newborns-and-early-life-exposure-to-endocrine-disrupting-chemicals-analysis-of-three-european-mother-child-cohorts
#13
Marijke de Cock, Michiel R de Boer, Eva Govarts, Nina Iszatt, Lubica Palkovicova, Marja H Lamoree, Greet Schoeters, Merete Eggesbø, Tomas Trnovec, Juliette Legler, Margot van de Bor
BACKGROUND: Various studies report interactions between thyroid hormones and early life chemical exposure. Our objective was to analyse associations between markers of endocrine disrupting chemical exposure and thyroid function in newborns, determined in heel prick blood spots. METHODS: Three European mother-child cohorts (FLEHSI - Belgium, HUMIS - Norway, and the PCB cohort - Slovakia. Total n=1784) were pooled for the purpose of this study. Data on Thyroid Stimulating Hormone (TSH) was obtained from national neonatal screening registries, and cord plasma and/or breast milk was collected to determine exposure to various chemicals...
March 13, 2017: Pediatric Research
https://www.readbyqxmd.com/read/28286539/potential-exposure-to-endocrine-disrupting-chemicals-and-selected-adverse-pregnancy-outcomes-a-follow-up-study-of-pregnant-women-referred-for-occupational-counselling
#14
Jessica Bengtsson, Pernille Søgaard Thygesen, Linda Kaerlev, Lisbeth E Knudsen, Jens Peter Bonde
BACKGROUND: Experimental evidence indicates that fetal exposure to xenobiotics with the potential to interfere with the endogenous steroid hormone regulation of fetal development may reduce birth weight. However, epidemiological studies are limited. The aim of the study was to investigate whether potential occupational exposure to endocrine disrupting chemicals (EDC) of the mother during pregnancy is associated with preterm birth and low birth weight. METHODS: Pregnant women referred to an Occupational Health Clinic (OHC) in two Danish regions (Copenhagen or Aarhus) between 1984 and 2010, suspected of being exposed to occupational reproductive hazards were included in the study...
2017: Journal of Occupational Medicine and Toxicology
https://www.readbyqxmd.com/read/28286207/virtual-screening-applications-in-short-chain-dehydrogenase-reductase-research
#15
REVIEW
Katharina R Beck, Teresa Kaserer, Daniela Schuster, Alex Odermatt
Several members of the short-chain dehydrogenase/reductase (SDR) enzyme family play fundamental roles in adrenal and gonadal steroidogenesis as well as in the metabolism of steroids, oxysterols, bile acids, and retinoids in peripheral tissues, thereby controlling the local activation of their cognate receptors. Some of these SDRs are considered as promising therapeutic targets, for example to treat estrogen-/androgen-dependent and corticosteroid-related diseases, whereas others are considered as anti-targets as their inhibition may lead to disturbances of endocrine functions, thereby contributing to the development and progression of diseases...
March 9, 2017: Journal of Steroid Biochemistry and Molecular Biology
https://www.readbyqxmd.com/read/28285737/lung-injury-induced-by-bisphenol-a-a-food-contaminant-is-ameliorated-by-selenium-supplementation
#16
Azza S Abedelhaffez, Ebtihal A Abd El-Aziz, Mohamed A Abdel Aziz, Asmaa M Ahmed
Bisphenol A (BPA), a widely used industrial chemical, is known to disrupt endocrine function. This study aimed to investigate the impact of chronic exposure to BPA on the lung tissue of adult male rats as well as any possible alleviating effects resulting from selenium (Se) treatment. Chronic exposure to BPA resulted in prominent inflammation and oxidative stress responses as evidenced by an increase in levels of malondialdehyde (MDA), reduced concentrations of superoxide dismutase (SOD), and upregulation of Interleukin-18 (IL-18) expression in lung tissue...
February 12, 2017: Pathophysiology: the Official Journal of the International Society for Pathophysiology
https://www.readbyqxmd.com/read/28285354/endocrine-disruption-oxidative-stress-and-testicular-damage-induced-by-4-nonylphenol-in-clarias-gariepinus-the-protective-role-of-cydonia-oblonga
#17
Alaa El-Din H Sayed, Rania F K Ismail
Exposure to xenoestrogens like 4-nonylphenol (NP) is recognized by disrupting endocrine functions and causes reproductive dysfunction in male fish. The present study aimed at investigating the 4-nonylphenol propensity to induce oxidative stress and hormonal disturbances in male catfish and at studying the protective role of quince (Cydonia oblonga). To fulfill this aim, catfish Clarias gariepinus were exposed to pure 100 μg/L 4-NP and to quince the leaf extract added to 4-NP, both for 15 days. The 4-NP exposure induced a marked increase in 17ß-estradiol (E2), LH, and cortisol, while thyroid hormone (TSH, T3), testosterone (T), and FSH levels noticeably decreased; however, 4-NP had no effect on T4 level...
March 11, 2017: Fish Physiology and Biochemistry
https://www.readbyqxmd.com/read/28285191/polychlorinated-biphenyls-153-induces-metabolic-dysfunction-through-activation-of-ros-nf-%C3%AE%C2%BAb-signaling-via-downregulation-of-hnf1b
#18
Hao Wu, Weihua Yu, Fansen Meng, Jie Mi, Jie Peng, Jiangzheng Liu, Xiaodi Zhang, Chunxu Hai, Xin Wang
Polychlorinated biphenyls (PCB) is a major type of persistent organic pollutants (POPs) that act as endocrine-disrupting chemicals. In the current study, we examined the mechanism underlying the effect of PCB-153 on glucose and lipid metabolism in vivo and in vitro. We found that PCB-153 induced per se and worsened high fat diet (HFD)-resulted increase of blood glucose level and glucose and insulin intolerance. In addition, PCB-153 induced per se and worsened HFD-resulted increase of triglyceride content and adipose mass...
March 7, 2017: Redox Biology
https://www.readbyqxmd.com/read/28284648/the-relative-risk-and-its-distribution-of-endocrine-disrupting-chemicals-pharmaceuticals-and-personal-care-products-to-freshwater-organisms-in-the-bohai-rim-china
#19
Meng Zhang, Yajuan Shi, Yonglong Lu, Andrew C Johnson, Suriyanarayanan Sarvajayakesavalu, Zhaoyang Liu, Chao Su, Yueqing Zhang, Monika D Juergens, Xiaowei Jin
In this study, the risks to aquatic organisms posed by 12 commonly detected pharmaceuticals and personal care products (PPCPs) and endocrine disrupting chemicals (EDCs) that are extensively used in Bohai coastal region of China were examined. These were linear alkylbenzene sulfonate (LAS), nonylphenol (NP), diethylhexyl phthalate (DEHP), norfloxacin (NOR), sulfamethoxazole (SMX), erythromycin (ERY), bisphenol A (BPA), ofloxacin (OFL), carbamazepine (CBZ), naproxen (NPX), atenolol (ATL) and metoprolol (MET)...
March 8, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28283302/perfluoroalkyl-substances-and-endometriosis-related-infertility-in-chinese-women
#20
Bin Wang, Rongrong Zhang, Fan Jin, Hangying Lou, Yuchan Mao, Wenting Zhu, Wei Zhou, Ping Zhang, Jun Zhang
Endometriosis is one of the main causes for female infertility. Previous studies suggested that perfluoroalkyl substances (PFASs), a group of ubiquitous environmental chemicals with properties of endocrine disruption and reproductive toxicity, were risk factors for endometriosis but there lacks direct evidence on the possible role of PFASs in endometriosis-related infertility. To fill this gap, we examined the association between PFASs and endometriosis-related infertility among Chinese reproductive-age women in a case-control study, which comprised 157 surgically confirmed endometriosis cases and 178 controls seeking infertility treatment because of male reproductive dysfunction in 2014 and 2015...
March 7, 2017: Environment International
keyword
keyword
94083
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"