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https://www.readbyqxmd.com/read/28727963/going-in-many-right-directions-all-at-once
#1
Susan T Fiske
When asked whether the field is going in the right direction, my answer is "yes, mostly." Policymakers' respect and the public's interest put us in the spotlight for our intrinsic strengths-but they also draw attention to our weaknesses as reflected by the replication crisis, about which reasonable opinions differ. Among other concerns, civility and mutual tolerance have sometimes been an issue in these debates. As an example of a constructive debate, our lab's recent experience with mutually respectful engagement has advanced solving one scientific puzzle...
July 2017: Perspectives on Psychological Science: a Journal of the Association for Psychological Science
https://www.readbyqxmd.com/read/28724750/disruption-of-a-structurally-important-extracellular-element-in-the-glycine-receptor-leads-to-decreased-synaptic-integration-and-signaling-resulting-in-severe-startle-disease
#2
Natascha Schaefer, Alexandra Berger, Johannes van Brederode, Fang Zheng, Yan Zhang, Sophie Leacock, Laura Littau, Sibylle Jablonka, Sony Malhotra, Maya Topf, Friederike Winter, Daria Davydova, Joseph W Lynch, Christopher J Paige, Christian Alzheimer, Robert J Harvey, Carmen Villmann
Functional impairments or trafficking defects of inhibitory glycine receptors (GlyRs) have been linked to human hyperekplexia/startle disease and autism spectrum disorder. We found that lack of synaptic integration of GlyRs, together with disrupted receptor function is responsible for a lethal startle phenotype in a novel spontaneous mouse mutant shaky, caused by a missense mutation Q177K located in the extracellular β8-β9 loop of the GlyR α1 subunit. Recently, structural data provided evidence that the flexibility of the β8-β9 loop is crucial for conformational transitions during opening and closing of the ion channel and represents a novel allosteric binding site in cys-loop receptors...
July 19, 2017: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/28723679/preparation-and-application-of-n-doped-carbon-nanotube-arrays-on-graphene-fibers
#3
Mochen Li, Xiaohong Zhang, Haibin Jiang, Xiang Wang, Yue Ru, Jinliang Qiao
A new kind of carbon hybrid material with unique structure, outstanding mechanical and functional properties is reported in this article. Nitrogen-doped carbon nanotube arrays with inside located Ni particles are in-situ grown on the surface of phenolic carbon modified graphene fibers during their conversion from graphene oxide fibers. The carbon hybrid fiber exhibits not only high tensile strength and elongation at break, but also excellent flexibility since the carbon nanotube arrays cover the all surface of highly strong graphene fiber...
July 19, 2017: Nanotechnology
https://www.readbyqxmd.com/read/28722593/the-benjamin-h-kean-travel-fellowship-in-tropical-medicine-assessment-of-impact-at-15-years
#4
Aubri S Carman, Chandy C John
The Benjamin H. Kean Fellowship in Tropical Medicine is an American Society of Tropical Medicine and Hygiene initiative that provides medical students with funding for international clinical or research experiences lasting at least 1 month. Of the 175 Kean fellows from 1998 to 2013, 140 had current available e-mails, and 70 of the 140 (50%) responded to a survey about their fellowship experience. Alumni indicated that the Kean Fellowship had a high impact on their career plans with regard to preparation for (N = 65, 94...
June 26, 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/28722465/overview-on-the-surface-functionalization-mechanism-and-determination-of-surface-functional-groups-of-plasma-treated-carbon-nanotubes
#5
Cafer Saka
The use of carbon materials for many applications is due to the unique diversity of structures and properties ranging from chemical bonds between the carbon atoms of the materials to nanostructures, crystallite alignment and microstructures. Carbon nanotubes and other nanoscale carbonaceous materials draw much attention due to their physical and chemical properties such as high strength, high resistance to corrosion, electrical and thermal conductivity, stability and a qualified adsorbent. Carbon-based nanomaterials, which have a relatively large specific area and layered structure, can be used as an adsorbent for efficient removal of organic and inorganic contaminants...
July 19, 2017: Critical Reviews in Analytical Chemistry
https://www.readbyqxmd.com/read/28722323/branched-aramid-nanofibers
#6
Jian Zhu, Ming Yang, Ahmet Emre, Joong Hwan Bahng, Lizhi Xu, Jihyeon Yeom, Bongjun Yeom, Yoonseob Kim, Kyle Johnson, Peter Green, Nicholas Alexander Kotov
Interconnectivity of molecular or nanoscale components in three-dimensional networks (3DNs) is essential for stress transfer in hydrogels, aerogels, and composites. Entanglement of nanoscale components in the network relies on weak short-range intermolecular interactions. The intrinsic stiffness and rod-like geometry of known nanofibers limits the cohesive energy of the physical crosslinks in 3DN materials. Nature realizes networked gels differently using components with extensive branching. Here, we show that branched aramid nanofibers (BANFs) readily produce 3DNs with high efficiency stress transfer...
July 18, 2017: Angewandte Chemie
https://www.readbyqxmd.com/read/28720907/top-down-fabrication-and-enhanced-active-area-electronic-characteristics-of-amorphous-oxide-nanoribbons-for-flexible-electronics
#7
Hyun-June Jang, Ki Joong Lee, Kwang-Won Jo, Howard E Katz, Won-Ju Cho, Yong-Beom Shin
Inorganic amorphous oxide semiconductor (AOS) materials such as amorphous InGaZnO (a-IGZO) possess mechanical flexibility and outstanding electrical properties, and have generated great interest for use in flexible and transparent electronic devices. In the past, however, AOS devices required higher activation energies, and hence higher processing temperatures, than organic ones to neutralize defects. It is well known that one-dimensional nanowires tend to have better carrier mobility and mechanical strength along with fewer defects than the corresponding two-dimensional films, but until now it has been difficult, costly, and impractical to fabricate such nanowires in proper alignments by either "bottom-up" growth techniques or by "top-down" e-beam lithography...
July 18, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28719990/radiographic-and-clinical-assessment-of-intramedullary-nail-fixation-for-the-treatment-of-unstable-metacarpal-fractures
#8
Ather Mirza, Justin Mirza, Chris Healy, Vishaaq Mathew, Brian Lee
BACKGROUND: The purpose of the article was to evaluate clinical and radiographic outcomes in a case series of unstable metacarpal fractures treated with flexible intramedullary nail (IMN) fixation. METHODS: A total of 55 patients with unstable metacarpal fractures between 2003 and 2010 were treated with IMN fixation and followed for a minimum of 1 year. The outcomes were assessed via a radiological study of longitudinal and angular collapse, Disabilities of the Arm, Shoulder, and Hand (DASH) score, total active range of motion (ROM) of the wrist, and grip strength testing...
March 1, 2017: Hand: Official Journal of the American Association for Hand Surgery
https://www.readbyqxmd.com/read/28716635/the-effects-of-strength-exercise-on-hippocampus-volume-and-functional-fitness-of-elderly-women
#9
Yun Sik Kim, Sang Keun Shin, Seung Baek Hong, Hak Jin Kim
BACKGROUND: Various positive effects of exercise on elderly women have been identified in many studies. Despite the importance of preserving the health of brain as well as body, few studies have investigated the effects of strength exercise on the brain health of elderly women to date. This study aimed to identify the effects of 24weeks of the Growing Stronger program on hippocampus volume and functional fitness of elderly women. METHODS: Twenty elderly women aged over 65 participated in this study...
July 14, 2017: Experimental Gerontology
https://www.readbyqxmd.com/read/28716108/esoteric-connective-tissue-therapy-for-chronic-low-back-pain-to-reduce-pain-and-improve-functionality-and-general-well-being-compared-with-physiotherapy-study-protocol-for-a-randomised-controlled-trial
#10
Christoph Schnelle, Steffen Messerschmidt, Eunice J Minford, Kate Greenaway-Twist, Maxine Szramka, Marianna Masiorski, Michelle Sheldrake, Mark Jones
BACKGROUND: Low back pain causes more global disability than any other condition. Once the acute pain becomes chronic, about two-thirds of sufferers will not fully recover after 1-2 years. There is a paucity of effective treatments for non-specific, chronic low back pain. It has been noted that low back pain is associated with changes in the connective tissue in the affected area, and a very low-impact treatment, Esoteric Connective Tissue Therapy (ECTT), has been developed to restore flexibility in connective tissue...
July 17, 2017: Trials
https://www.readbyqxmd.com/read/28715338/closed-loop-neurostimulators-a-survey-and-a-seizure-predicting-design-example-for-intractable-epilepsy-treatment
#11
Hossein Kassiri, Sana Tonekaboni, M Tariqus Salam, Nima Soltani, Karim Abdelhalim, Jose Luis Perez Velazquez, Roman Genov
First, existing commercially available open-loop and closed-loop implantable neurostimulators are reviewed and compared in terms of their targeted application, physical size, system-level features, and performance as a medical device. Next, signal processing algorithms as the primary strength point of the closed-loop neurostimulators are reviewed, and various design and implementation requirements and trade-offs are discussed in details along with quantitative examples. The review results in a set of guidelines for algorithm selection and evaluation...
July 17, 2017: IEEE Transactions on Biomedical Circuits and Systems
https://www.readbyqxmd.com/read/28714343/a-randomized-controlled-trial-of-a-combined-self-management-and-exercise-intervention-for-elderly-people-with-osteoarthritis-of-the-knee-the-ple-2-no-program
#12
Priscila Marconcin, Margarida Espanha, Júlia Teles, Paulo Bento, Pedro Campos, Rui André, Flávia Yázigi
OBJECTIVE: To assess the effectiveness of a 12-week self-management and exercise intervention (the PLE(2)NO program) in elderly individuals with knee osteoarthritis. DESIGN: Randomized controlled trial. SETTING: Four different community settings. SUBJECTS: Eighty individuals aged 60 years or older with clinical and radiographic knee osteoarthritis enrolled in the study. INTERVENTION: A combined self-management and exercise intervention (treatment group) and an educational intervention (control group)...
July 1, 2017: Clinical Rehabilitation
https://www.readbyqxmd.com/read/28702663/tuning-phase-and-aging-of-dna-hydrogels-through-molecular-design
#13
Dan T Nguyen, Omar A Saleh
The programmable, sequence-dependent hybridization of DNA has spurred the development of DNA hydrogels, polymer networks that swell in water and are comprised either entirely or partially of DNA. Specific applications require hydrogels of particular structure for optimal functionality. Here, we use self-assembling, multi-valent DNA nanostars to examine how hydrogel structure is influenced by the non-equilibrium dynamics of its interacting components. We show that hydrogel aging kinetics - from an arrested, solid-like percolated network to an equilibrium, phase-separated liquid analogous to coacervates - are modulated by DNA hybridization strength and ion-specific nanostar internal flexibility...
July 12, 2017: Soft Matter
https://www.readbyqxmd.com/read/28701981/language-mediated-concept-activation-in-bilingual-memory-facilitates-cognitive-flexibility
#14
Anatoliy V Kharkhurin
This is the first attempt of empirical investigation of language mediated concept activation (LMCA) in bilingual memory as a cognitive mechanism facilitating divergent thinking. Russian-English bilingual and Russian monolingual college students were tested on a battery of tests including among others Abbreviated Torrance Tests for Adults assessing divergent thinking traits and translingual priming (TLP) test assessing the LMCA. The latter was designed as a lexical decision priming test, in which a prime and a target were not related in Russian (language of testing), but were related through their translation equivalents in English (spoken only by bilinguals)...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28701449/the-change-program-exercise-intervention-in-primary-care
#15
Doug Klein, Khursheed Jeejeebhoy, Angelo Tremblay, Matthew Kallio, Caroline Rheaume, Serena Humphries, Dawna Royall, Paula Brauer, Daren Heyland, Rupinder Dhaliwal, David M Mutch
PROBLEM ADDRESSED: Primary care settings require a feasible program for integrating lifestyle interventions, which can reverse metabolic abnormalities, for patients in practice. OBJECTIVE OF PROGRAM: To integrate a lifestyle intervention program into existing primary care clinics with an interprofessional approach that includes dietitians and kinesiologists. PROGRAM DESCRIPTION: Canadian Health Advanced by Nutrition and Graded Exercise (CHANGE) provides a personalized approach to nutrition and exercise modification focusing on patients with metabolic syndrome...
July 2017: Canadian Family Physician Médecin de Famille Canadien
https://www.readbyqxmd.com/read/28696658/ultrasensitive-wearable-soft-strain-sensors-of-conductive-self-healing-and-elastic-hydrogels-with-synergistic-soft-and-hard-hybrid-networks
#16
Yan-Jun Liu, Wen-Tao Cao, Ming-Guo Ma, Pengbo Wan
Robust, stretchable and strain-sensitive hydrogels have recently attracted immense research interest due to their potential application in wearable strain sensors. The integration of the synergistic characteristics of decent mechanical properties, reliable self-healing capability, and high sensing sensitivity for fabricating conductive, elastic, self-healing, and strain-sensitive hydrogels is still a great challenge. Inspired by the mechanically excellent and self-healing biological soft tissues with hierarchical network structures, herein, functional network hydrogels are fabricated by the interconnection between a "soft" homogeneous polymer network and a "hard" dynamic ferric (Fe3+) cross-linked cellulose nanocrystals (CNCs-Fe(3+)) network...
July 11, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28693716/psychometric-properties-of-the-spanish-version-of-the-family-adaptability-and-cohesion-evaluation-scale-iv
#17
Ana Martínez-Pampliega, Laura Merino, Leire Iriarte, David H Olson
INTRODUCTION: Building on the expanding cross cultural interest in FACES, the Spanish version of the Family Adaptability and Cohesion Evaluation Scale (FACES IV), aimed at the assessment of the dimensions of cohesion and flexibility of the Circumplex Model, was validated following the author´s guidelines. METHOD: The sample was composed by 665 college students. Besides, FACES II was also used and family communication, satisfaction, stress and strengths were also measured...
August 2017: Psicothema
https://www.readbyqxmd.com/read/28689980/the-contribution-of-area-mt-to-visual-motion-perception-depends-on-training
#18
Liu D Liu, Christopher C Pack
Perceptual decisions require the transformation of raw sensory inputs into cortical representations suitable for stimulus discrimination. One of the best-known examples of this transformation involves the middle temporal area (MT) of the primate visual cortex. Area MT provides a robust representation of stimulus motion, and previous work has shown that it contributes causally to performance on motion discrimination tasks. Here we report that the strength of this contribution can be highly plastic: depending on the recent training history, pharmacological inactivation of MT can severely impair motion discrimination, or it can have little detectable influence...
July 19, 2017: Neuron
https://www.readbyqxmd.com/read/28689647/effectiveness-of-a-physical-activity-programme-based-on-the-pilates-method-in-pregnancy-and-labour
#19
Luciano Rodríguez-Díaz, Carlos Ruiz-Frutos, Juana María Vázquez-Lara, Jesús Ramírez-Rodrigo, Carmen Villaverde-Gutiérrez, Gema Torres-Luque
OBJECTIVE: To assess the effectiveness and safety of a physical activity programme based on use of the Pilates method, over eight weeks in pregnant women, on functional parameters, such as weight, blood pressure, strength, flexibility and spinal curvature, and on labour parameters, such as, type of delivery, episiotomy, analgesia and newborn weight. METHOD: A randomized clinical trial was carried out on pregnant women, applying a programme of physical activity using the Pilates method, designed specifically for this population...
July 6, 2017: Enfermería Clínica
https://www.readbyqxmd.com/read/28682591/robust-bioinspired-graphene-film-via-%C3%AF-%C3%AF-cross-linking
#20
Hong Ni, Feiyu Xu, Antoni P Tomsia, Eduardo Saiz, Lei Jiang, Qunfeng Cheng
Graphene composite films inspired by nacre are the subject of ongoing research efforts to optimize their properties for applications in flexible energy devices. Noncovalent interactions do not cause interruption of the delocalized conjugated π-electron system, thus preserving graphene's excellent properties. Herein, we synthesized a conjugated molecule with pyrene groups on both ends of a long linear chain (AP-DSS) from 1-aminopyrene (AP) and disuccinimidyl suberate (DSS). The AP-DSS molecules are used to cross-link adjacent graphene nanosheets via π-π interfacial interactions to improve properties of graphene films...
July 17, 2017: ACS Applied Materials & Interfaces
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