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Spleen anatomy

Modesta Makungu, Wencke M du Plessis, Michelle Barrows, Hermanus B Groenewald, Katja N Koeppel
The red panda ( Ailurus fulgens) is classified as an endangered species by the International Union for Conservation of Nature and Natural Resources. The aim of this study was to describe the normal radiographic abdominal anatomy in red pandas to provide guidance for clinical use. Radiography of the abdomen was performed in nine captive red pandas during their annual health examinations. Seven of nine animals had six lumbar vertebrae. The sacrum consisted mainly (8/9) of three fused segments. Hypaxial muscles were easily seen in animals weighing 5 kg and above...
March 2018: Journal of Zoo and Wildlife Medicine: Official Publication of the American Association of Zoo Veterinarians
Changming Huang, Mi Lin
According to Japanese gastric cancer treatment guidelines, the standard operation for locally advanced upper third gastric cancer is the total gastrectomy with D2 lymphadenectomy, which includes the dissection of the splenic hilar lymph nodes. With the development of minimally invasive ideas and surgical techniques, laparoscopic spleen-preserving splenic hilar lymph node dissection is gradually accepted. It needs high technical requirements and should be carried out by surgeons with rich experience of open operation and skilled laparoscopic techniques...
February 25, 2018: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
Ophélie Cojean, Claire Vergneau-Grosset, Isabelle Masseau
Captive leopard geckos (Eublepharis macularius) often present to the exotic clinic for gastrointestinal impactions, follicular stasis, or dystocia. To our knowledge, normal ultrasonographic anatomy of these lizards has not been described. The objectives of this prospective, anatomic, analytical study were to develop ultrasound techniques for this species and to describe the normal sonographic anatomy of the head, coelomic cavity, and tail. Eleven, healthy, female leopard geckos were included. A linear array 13-18 MHz transducer was used...
February 19, 2018: Veterinary Radiology & Ultrasound
Bruno Oliveira, Sandro Queirós, Pedro Morais, Helena R Torres, João Gomes-Fonseca, Jaime C Fonseca, João L Vilaça
Anatomical evaluation of multiple abdominal and thoracic organs is generally performed with computed tomography images. Owing to the large field-of-view of these images, automatic segmentation strategies are typically required, facilitating the clinical evaluation. Multi-atlas segmentation (MAS) strategies have been widely used with this process, requiring multiple alignments between the target image and the set of known datasets, and subsequently fusing the alignment results to obtain the final segmentation...
February 2, 2018: Medical Image Analysis
Sha-Sha Zhao, Li-Xun Guan, Zhe Gao, Fei-Yan Wang, Li-Li Wang, Chun-Ji Gao
OBJECTIVE: To establish the animal model of luciferase-transfected A20 murine B cell lymphoma, so as to provide experimental tools to explore the effect of graft versus tumor. METHODS: Luciferase- labeled A20 cells were cloned with puromycin selection. Transfected A20 cells and C57BL/6 bone marrow were inoculated into the irradiated BALB/c mice by injection in tailvein to establish the transplantation model. The bioluminescent imaging technique was used to monitor the tumor growth, and then the survival, body weight, tumor formation and pathological characteristics of target organs were observed...
February 2018: Zhongguo Shi Yan Xue Ye Xue za Zhi
Decheng Chen
Based on the sancai (literally three talents referring to "earth", "human" and "heaven") and wuti (literally five organs referring to skin, muscle, vessel, tendon and bone, which correspond to five internal organs: lungs, spleen, heart, liver and kidney respectively) in Neijing (Internal Classic), as well as the tissue structure theory of modern anatomy, and in combination with the clinical practice of acupuncture by the author in the past over 30 years, it is proposed that four layers are divided in needling depth of acupuncture...
November 12, 2017: Zhongguo Zhen Jiu, Chinese Acupuncture & Moxibustion
Qing He, Hua Gao, Meng Gao, Shengmei Qi, Kun Yang, Yingqi Zhang, Junzhi Wang
The objective of this study is to determine the immunogenicity and safety of our novel anti-gastrin vaccine that is composed of the common amino-terminal portions of human carboxy-amidated gastrin-17 (G17) and glycine-extended gastrin-17 (gly-G17) as well as the common carboxy-terminal portion of the gastrin precursor progastrin (in a 50:50 mixture) all covalently linked to tetanus toxoid (TT) via peptide spacers. The vaccine, or immunogen, was injected intramuscularly into the legs of BALB/c mice, which produced high serum titres of specific IgG antibodies and IFN-γ in their spleen cells, identifiable by enzyme-linked immunosorbent assay (ELISA) and enzyme-linked immunospot assay (ELISPOT), respectively...
January 3, 2018: Vaccine
Dzenan Jahic, Eldan Kapur, Edin Begic, Enver Zerem
Introduction: In this paper, we report our experience with a case of primary hydatid cyst involving only the spleen in a 27-year-old sportsman treated by PAIR technique. Case Report: Five years before, a 27-year-old handball player being admitted to our hospital, it was detected the cyst in his spleen which size was 35 x 30 mm in diameter, by abdominal ultrasound during a systematic examination. There was no pain or any other symptoms at that time. Tests on the presence of echinococcus cysts were negative...
December 2017: Acta Informatica Medica: AIM
Jishuai Cheng, Zheng Yuan, Wenjing Yang, Chang Xu, Wei Cong, Lifang Lin, Shanmin Zhao, Wei Sun, Xiaosong Bai, Shufang Cui
The domestic and foreign scholars have studied naked mole rats more focused on the respect such as its long life, resistant to low oxygen, little spontaneous tumor, but the study of the immune system is little. In this study, we compared the anatomy and tissue morphology of NMR and ICR mouse spleens and found that the gross appearance of the NNMR spleen differed from ICR. There were more macrophages in NNMR spleens than in ICR spleens. Furthermore, we focused on the differences of macrophages. We compared their phagocytic capabilities and the data showed that NNMR macrophages are more phagocytic than ICR mouse macrophages...
November 14, 2017: Oncotarget
Marco Pizzi, Felicia Chaviano, Massimo Rugge, Attilio Orazi
Marcello Malpighi (1628-1694) is one of the most important anatomists and physicians in the history of medicine. His contributions to the understanding of human anatomy and physiology span from the first description of capillary circulation to a thorough analysis of the structure and function of body glands. Malpighi believed that most organs consisted of glandular structures, whose distribution and microscopic features determine each organ-specific function. He also applied this view to the study of spleen anatomy, which he recognized as composed of 2 distinct anatomic compartments (ie, the red and the white pulp)...
February 2018: Human Pathology
S Gill, M Kavanagh, W Cherry, C Bourque, D Caldwell, G Wang, G Bondy
A 90-day gavage study was conducted with 0.0, 0.02, 0.075, 0.25, 1.0 and 4.0 mg/kg bw/day dose groups of 3-methylfuran to identify a no-observed adverse effect level for hepatotoxicity and to characterize non-neoplastic effects including changes in gross anatomy, histopathology, clinical biochemistry and hematology. There were significant changes in the serum clinical biochemistry markers related to liver injury where males were more affected than the females for most parameters analysed. The serum liver injury marker γ-glutamyltransferase, alanine and aspartate aminotransferases were significantly increased in males in the 4...
January 2018: Food and Chemical Toxicology
Naoki Matsumura, Hiromi Tokumura, Fumito Saijo, Yu Katayose
BACKGROUND: The splenic flexure (SF) anatomy is complex due to multiple vessels, surrounding organs, layers, and irregular adhesions [1-3]. METHODS: Our laparoscopic approach involves a lateral-to-medial approach to the left-sided transverse mesocolon (TM), a medial-to-lateral approach to the left mesocolon (LM), and take-down of the remnant SF. First, the omental bursa is opened and its posterior wall and the anterior layer of the TM are dissected along the pancreas, where a gauze is placed...
October 26, 2017: Surgical Endoscopy
Raquel Sartor, Thiago R Müller, Maria J Mamprim, Carlos R Teixeira, Livia P de Souza, Ricardo C Lehmkuhl, Marilia G Luciani
Abdominal ultrasonography was performed in six healthy adult brown howler monkeys Alouatta fusca and the normal ultrasonographic anatomy of the liver, gallbladder, stomach and urinary tract described for the first time. Findings were compared with post-mortem studies. The renal cortex was isoechoic to the spleen and isoechoic or hyperechoic to the liver. Kidney length and renal arterial resistive index, systolic and diastolic velocity were calculated. The liver showed a homogeneous hypoechogenic echotexture...
February 2017: Veterinary Medicine and Science
Kazuhiro Matsumoto, Akira Miyajima, Keishiro Fukumoto, Akari Komatsuda, Naoya Niwa, Seiya Hattori, Toshikazu Takeda, Eiji Kikuchi, Hiroshi Asanuma, Mototsugu Oya
Objective: It is considered that laparoscopic single-site surgery should be performed by specially trained surgeons because of the technical difficulty in using special instruments through limited access. We investigated suitable patients for single-port laparoscopic radical nephrectomy, focusing on the anatomy and distribution of the renal artery and vein. Methods: This retrospective study was conducted in 52 consecutive patients who underwent single-port radical nephrectomy by the transperitoneal approach...
October 1, 2017: Japanese Journal of Clinical Oncology
Federico Coccolini, Giulia Montori, Fausto Catena, Yoram Kluger, Walter Biffl, Ernest E Moore, Viktor Reva, Camilla Bing, Miklosh Bala, Paola Fugazzola, Hany Bahouth, Ingo Marzi, George Velmahos, Rao Ivatury, Kjetil Soreide, Tal Horer, Richard Ten Broek, Bruno M Pereira, Gustavo P Fraga, Kenji Inaba, Joseph Kashuk, Neil Parry, Peter T Masiakos, Konstantinos S Mylonas, Andrew Kirkpatrick, Fikri Abu-Zidan, Carlos Augusto Gomes, Simone Vasilij Benatti, Noel Naidoo, Francesco Salvetti, Stefano Maccatrozzo, Vanni Agnoletti, Emiliano Gamberini, Leonardo Solaini, Antonio Costanzo, Andrea Celotti, Matteo Tomasoni, Vladimir Khokha, Catherine Arvieux, Lena Napolitano, Lauri Handolin, Michele Pisano, Stefano Magnone, David A Spain, Marc de Moya, Kimberly A Davis, Nicola De Angelis, Ari Leppaniemi, Paula Ferrada, Rifat Latifi, David Costa Navarro, Yashuiro Otomo, Raul Coimbra, Ronald V Maier, Frederick Moore, Sandro Rizoli, Boris Sakakushev, Joseph M Galante, Osvaldo Chiara, Stefania Cimbanassi, Alain Chichom Mefire, Dieter Weber, Marco Ceresoli, Andrew B Peitzman, Liban Wehlie, Massimo Sartelli, Salomone Di Saverio, Luca Ansaloni
Spleen injuries are among the most frequent trauma-related injuries. At present, they are classified according to the anatomy of the injury. The optimal treatment strategy, however, should keep into consideration the hemodynamic status, the anatomic derangement, and the associated injuries. The management of splenic trauma patients aims to restore the homeostasis and the normal physiopathology especially considering the modern tools for bleeding management. Thus, the management of splenic trauma should be ultimately multidisciplinary and based on the physiology of the patient, the anatomy of the injury, and the associated lesions...
2017: World Journal of Emergency Surgery: WJES
Jishuai Cheng, Zheng Yuan, Wenjing Yang, Chang Xu, Wei Cong, Lifang Lin, Shanmin Zhao, Wei Sun, Xiaosong Bai, Shufang Cui
The domestic and foreign scholars have studied naked mole rats more focused on the respect such as its long life, resistant to low oxygen, little spontaneous tumor, but the study of the immune system is little. In this study, we compared the anatomy and tissue morphology of NMR and ICR mouse spleens and found that the gross appearance of the NNMR spleen differed from ICR. There were more macrophages in NNMR spleens than in ICR spleens. Furthermore, we focused on the differences of macrophages. We compared their phagocytic capabilities and the data showed that NNMR macrophages are more phagocytic than ICR mouse macrophages...
July 28, 2017: Oncotarget
Hideki Ujiie, Tatsuya Kato, Hsin-Pei Hu, Patrycja Bauer, Priya Patel, Hironobu Wada, Daiyoon Lee, Kosuke Fujino, Colin Schieman, Andrew Pierre, Thomas K Waddell, Shaf Keshavjee, Gail E Darling, Kazuhiro Yasufuku
BACKGROUND: Surgical trainees are required to develop competency in a variety of laparoscopic operations. Developing laparoscopic technical skills can be difficult as there has been a decrease in the number of procedures performed. This study aims to develop an inexpensive and anatomically relevant model for training in laparoscopic foregut procedures. METHODS: An ex vivo, anatomic model of the human upper abdomen was developed using intact porcine esophagus, stomach, diaphragm and spleen...
June 2017: Journal of Thoracic Disease
Kahkashan Rashid, Sayantani Chowdhury, Sumit Ghosh, Parames C Sil
The present study was aimed to determine the curative role of curcumin against diabetes induced oxidative stress and its associated splenic complications. Diabetes was induced in the experimental rats via the intraperitoneal administration of a single dose of STZ (65mgkg(-1)body weight). Increased blood glucose and intracellular ROS levels along with decreased body weight, the activity of cellular antioxidant enzymes and GSH/GSSG ratio were observed in the diabetic animals. Histological assessment showed white pulp depletion and damaged spleen anatomy in these animals...
November 1, 2017: Biochemical Pharmacology
David Bergeron, Stéphane Poulin, Robert Laforce
Niemann-Pick disease type C (NPC) is a rare lysosomal storage disorder causing an intracellular lipid trafficking defect and varying damage to the spleen, liver, and central nervous system. The adult form, representing approximately 20% of the cases, is associated with progressive cognitive decline. Intriguingly, brains of adult NPC patients exhibit neurofibrillary tangles, a characteristic hallmark of Alzheimer's disease (AD). However, the cognitive, psychiatric, and neuropathological features of adult NPC and their relation to AD have yet to be explored...
June 30, 2017: Cognitive Neuropsychology
Ivan Varga, Jozef Babala, David Kachlik
A thorough understanding of the anatomy, physiology, and development of the spleen is essential for determining the pathophysiological mechanisms underpinning splenic diseases and congenital variations. The aim of this review is to briefly summarize current knowledge regarding the normal development of the spleen, and to provide an overview of clinically relevant congenital splenic variations. These include such variations as asplenia, polysplenia, hyposplenia, lobulation of spleen, accessory spleens, accessory splenic nodules, wandering spleen, splenogonadal and splenopancreatic fusion, splenic cysts, and cavernous haemangioma of the spleen...
June 19, 2017: Surgical and Radiologic Anatomy: SRA
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