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Kidney anatomy

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https://www.readbyqxmd.com/read/28205351/functional-assessment-of-the-kidneys-in-a-10%C3%A2-month-old-child-with-renal-artery-stenosis-by-intravoxel-incoherent-motion
#1
Jochen Herrmann, Harald Ittrich, Michael Gerhard Kaul, Michael Groth, Magdalini Tozakidou, Martin Blohm, Jun Oh, Gerhard Adam
Renovascular stenosis is an important cause for arterial hypertension in childhood. We report a 10-month-old girl with arterial hypertension caused by right-sided renal artery stenosis detected by Doppler ultrasound. Magnetic resonance imaging (MRI) was performed before renal artery angioplasty to depict vascular anatomy in detail and to retrieve additional functional information of the kidneys by analysis of intravoxel incoherent motion (IVIM). The value of quantitative diffusion weighted imaging of the kidneys prior to percutaneous transluminal renal angioplasty (PTRA) is discussed...
March 2017: Nephrology
https://www.readbyqxmd.com/read/28197028/gross-morphological-study-of-the-renal-pelvicalyceal-patterns-in-human-cadaveric-kidneys
#2
T S R Anjana, Elangovan Muthian, Sivakami Thiagarajan, Sumathi Shanmugam
INTRODUCTION: The knowledge of detailed calyceal anatomy is essential for performing urologic procedures such as percutaneous nephrolithotomy, percutaneous nephrostomy, flexible ureterorenoscopy, endopyelotomy, and retrograde renal surgery. This study was performed to analyze the various patterns of pelvicalyceal system in the South Indian population, and compare these with previously published studies in different populations. METHODS: The study was conducted in 100 kidney specimens...
January 2017: Indian Journal of Urology: IJU: Journal of the Urological Society of India
https://www.readbyqxmd.com/read/28197027/comparison-of-computed-tomographic-angiography-and-noncontrast-magnetic-resonance-angiography-in-preoperative-evaluation-of-living-renal-donors
#3
Abhijit Dnyandeo Patil, K Shailage, Jeyaseelan Nadarajah, P Harigovind, R Krishna Mohan
INTRODUCTION: The computed tomographic angiography (CTA) renal donor protocol is an established method of preoperative renal vascular pedicle evaluation in prospective renal donors. However, CTA is associated with significant radiation exposure and intravenous contrast administration. The newer noncontrast-enhanced magnetic resonance angiography (NCE-MRA) techniques, especially arterial spin labeling (ASL) with steady-state free precession (SSFP) hold promise as an effective alternative...
January 2017: Indian Journal of Urology: IJU: Journal of the Urological Society of India
https://www.readbyqxmd.com/read/28196661/pediatric-medical-device-development-by-surgeons-via-capstone-engineering-design-programs
#4
Bryan S Sack, Rodolfo A Elizondo, Gene O Huang, Nicolette Janzen, Jimmy Espinoza, Magdalena Sanz-Cortes, Jennifer E Dietrich, Julie Hakim, Eric Richardson, Maria Oden, John Hanks, Balakrishna Haridas, James F Hury, Chester J Koh
BACKGROUND: There is a need for pediatric medical devices that accommodate the unique physiology and anatomy of pediatric patients that is increasingly receiving more attention. However, there is limited literature on the programs within children's hospitals and academia that can support pediatric device development. We describe our experience with pediatric device design utilizing collaborations between a children's hospital and two engineering schools. METHODS: Utilizing the academic year as a timeline, unmet pediatric device needs were identified by surgical faculty and matched with an engineering mentor and a team of students within the Capstone Engineering Design programs at two universities...
February 6, 2017: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/28117559/anatomic-study-of-renal-arterial-vasculature-and-its-potential-implication-on-partial-nephrectomy
#5
Veronica Macchi, Alessandro Crestani, Andrea Porzionato, Maria Martina Sfriso, Aldo Morra, Marta Rossanese, Giacomo Novara, Raffaele De Caro, Vincenzo Ficarra
BACKGROUND AND OBJECTIVES: A detailed understanding of surgical anatomy is an essential requisite to maximize perioperative and functional outcomes of partial nephrectomy. The objectives of this study were 1) to validate the Graves classification and 2) to verify the real absence of collateral arterial blood-supply between different renal segments. MATERIAL AND METHODS: The study was performed on 15 normal kidneys sampled from 8 un-embalmed cadavers. Kidneys with the surrounding perirenal fat tissue were removed en bloc with the abdominal segment of the aorta...
January 24, 2017: BJU International
https://www.readbyqxmd.com/read/28116780/r1-autonomic-nervous-system-in-acute-kidney-injury
#6
REVIEW
Dagmara Hering, Pawel J Winklewski
Acute kidney injury (AKI) is a rapid loss of kidney function resulting in accumulation of end metabolic products and associated abnormalities in fluid, electrolyte and acid-base homeostasis. The pathophysiology of AKI is complex and multifactorial involving numerous vascular, tubular and inflammatory pathways. Neurohumoral activation with heightened activity of the sympathetic nervous system and renin-angiotensin-aldosterone system play a critical role in this scenario. Inflammation and/or local renal ischaemia are underlying mechanisms triggering renal tissue hypoxia and resultant renal microcirculation dysfunction; a common feature of AKI occurring in numerous clinical conditions leading to a high morbidity and mortality rate...
February 2017: Clinical and Experimental Pharmacology & Physiology
https://www.readbyqxmd.com/read/28112399/estimating-organ-doses-from-tube-current-modulated-ct-examinations-using-a-generalized-linear-model
#7
Maryam Bostani, Kyle McMillan, Peiyun Lu, Grace Hyun J Kim, Dianna Cody, Gary Arbique, S Bruce Greenberg, John J DeMarco, Chris H Cagnon, Michael F McNitt-Gray
PURPOSE: Currently available Computed Tomography dose metrics are mostly based on fixed tube current Monte Carlo (MC) simulations and/or physical measurements such as the size specific dose estimate (SSDE). In addition to not being able to account for Tube Current Modulation (TCM), these dose metrics do not represent actual patient dose. The purpose of this study was to generate and evaluate a dose estimation model based on the Generalized Linear Model (GLM) which extends the ability to estimate organ dose from tube current modulated examinations by incorporating regional descriptors of patient size, scanner output and other scan-specific variables as needed...
January 23, 2017: Medical Physics
https://www.readbyqxmd.com/read/28077268/development-of-high-resolution-3d-hyperpolarized-carbon-13-mr-molecular-imaging-techniques
#8
Eugene Milshteyn, Cornelius von Morze, Galen D Reed, Hong Shang, Peter J Shin, Zihan Zhu, Hsin-Yu Chen, Robert Bok, Andrei Goga, John Kurhanewicz, Peder E Z Larson, Daniel B Vigneron
The goal of this project was to develop and apply techniques for T2 mapping and 3D high resolution (1.5mm isotropic; 0.003cm(3)) (13)C imaging of hyperpolarized (HP) probes [1-(13)C]lactate, [1-(13)C]pyruvate, [2-(13)C]pyruvate, and [(13)C,(15)N2]urea in vivo. A specialized 2D bSSFP sequence was implemented on a clinical 3T scanner and used to obtain the first high resolution T2 maps of these different hyperpolarized compounds in both rats and tumor-bearing mice. These maps were first used to optimize timings for highest SNR for single time-point 3D bSSFP acquisitions with a 1...
January 7, 2017: Magnetic Resonance Imaging
https://www.readbyqxmd.com/read/28048032/su-f-j-63-abdominal-diameter-changes-in-children-during-volumetric-modulated-arc-therapy-vmat-is-re-planning-needed
#9
F Guerreiro, G Janssens, E Seravalli, B Raaymakers
PURPOSE: To investigate the dosimetric impact of daily changes in patient's diameter, due to weight gain/loss and air in the bowel, based on CBCT information during radiotherapy treatment of pediatric abdominal tumors. METHODS: 10 pediatric patients with neuroblastoma (n=6) and Wilms' (n=4) tumors were included. Available CBCTs were affinely registered to the planning CT for daily set-up variations corrections. A density override approach assigning air-density to the random air pockets and water-density to the remaining anatomy was used to determine the CBCT and CT dose...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047839/th-cd-206-08-an-anthropopathic-deformable-phantom-for-geometric-and-dose-accumulation-accuracy-validation-of-deformable-image-registration
#10
Y Liao, H Chen, J Chen, X Gu, X Zhen, L Zhou
PURPOSE: To design and construct a three-dimensional (3D) anthropopathic abdominal phantom for evaluating deformable image registration (DIR) accuracy on images and dose deformation in adaptive radiation therapy (ART). METHOD: Organ moulds, including liver, kidney, spleen, stomach, vertebra and two metastasis tumors, are 3D printed using the contours from an ovarian cancer patient. The organ moulds are molded with deformable gels that made of different mixtures of polyvinyl chloride (PVC) and the softener dioctyl terephthalate...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047024/su-d-207a-07-the-effects-of-inter-cycle-respiratory-motion-variation-on-dose-accumulation-in-single-fraction-mr-guided-sbrt-treatment-of-renal-cell-carcinoma
#11
B Stemkens, M Glitzner, C Kontaxis, B Denis de Senneville, F Prins, Spm Crijns, L Kerkmeijer, J Lagendijk, Cat van den Berg, Rhn Tijssen
PURPOSE: To assess the dose deposition in simulated single-fraction MR-Linac treatments of renal cell carcinoma, when inter-cycle respiratory motion variation is taken into account using online MRI. METHODS: Three motion characterization methods, with increasing complexity, were compared to evaluate the effect of inter-cycle motion variation and drifts on the accumulated dose for an SBRT kidney MR-Linac treatment: 1) STATIC, in which static anatomy was assumed, 2) AVG-RESP, in which 4D-MRI phase-volumes were time-weighted, based on the respiratory phase and 3) PCA, in which 3D volumes were generated using a PCA-model, enabling the detection of inter-cycle variations and drifts...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28011754/logic-programming-to-infer-complex-rna-expression-patterns-from-rna-seq-data
#12
Tyler Weirick, Giuseppe Militello, Yuliya Ponomareva, David John, Claudia Döring, Stefanie Dimmeler, Shizuka Uchida
To meet the increasing demand in the field, numerous long noncoding RNA (lncRNA) databases are available. Given many lncRNAs are specifically expressed in certain cell types and/or time-dependent manners, most lncRNA databases fall short of providing such profiles. We developed a strategy using logic programming to handle the complex organization of organs, their tissues and cell types as well as gender and developmental time points. To showcase this strategy, we introduce 'RenalDB' (http://renaldb.uni-frankfurt...
December 22, 2016: Briefings in Bioinformatics
https://www.readbyqxmd.com/read/28000646/renal-cell-carcinoma-in-a-horseshoe-kidney-report-of-a-rare-disease
#13
Kehinde Habeeb Tijani, Rufus Wale Ojewola, Dubem E Orakwe, Abisola E Oliyide
A horseshoe kidney (HSK) is the most common congenital renal fusion anomaly. HSKs are more likely than normal kidneys to have associated problems of stones, ureteropelvic junction obstruction, stasis and infection. However, they do not have an increased incidence of renal cell carcinoma when compared to normal kidneys. Due to its rarity, accurate diagnosis may be difficult. Of similar significance is the fact that problems may arise during surgery on these kidneys due to altered anatomy and aberrant blood supply...
October 2016: Nigerian Postgraduate Medical Journal
https://www.readbyqxmd.com/read/27986484/a-comparison-of-brachial-artery-brachial-vein-arteriovenous-fistulas-with-arteriovenous-grafts-in-patients-with-poor-superficial-venous-anatomy
#14
Xuan-Binh D Pham, Jerry J Kim, Ezinne J Ihenachor, Aaron B Parrish, Jenny D Bleck, Amy H Kaji, Matthew C Koopmann, Christian de Virgilio
OBJECTIVE: The autogenous arteriovenous fistula (AVF) has been shown to be superior to the arteriovenous graft (AVG) with respect to cost, complications, and primary patency. Therefore, the National Kidney Foundation Disease Outcomes Quality Initiative guidelines recommend reserving AVGs for patients who do not have adequate superficial venous anatomy to support AVF placement. The brachial artery-brachial vein arteriovenous fistula (BVAVF) has emerged as an autologous last-effort alternative...
February 2017: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/27885585/the-conundrums-of-chronic-kidney-disease-and-aging
#15
REVIEW
Richard J Glassock, Aleksandar Denic, Andrew D Rule
Chronic kidney disease (CKD), as presently defined, is a common disorder. Aging is a nearly universal phenomenon that can affect renal anatomy and function, but at variable rates in individuals. Loss of nephrons and a decline in glomerular filtration rate (GFR) is a characteristic of normal aging, called renal senescence. Using fixed and absolute thresholds for defining CKD on the basis of GFR for all ages may lead to diagnostic uncertainty (a conundrum) in both young and older subjects. This brief review will consider the physiological and anatomical changes of the kidney occurring in the process of normal renal senescence focusing on GFR and will examine the relevance of these observation for the diagnosis of CKD using GFR as the distinguishing parameter...
November 25, 2016: Journal of Nephrology
https://www.readbyqxmd.com/read/27862866/utility-of-patient-specific-silicone-renal-models-for-planning-and-rehearsal-of-complex-tumour-resections-prior-to-robot-assisted-laparoscopic-partial-nephrectomy
#16
Friedrich-Carl von Rundstedt, Jason M Scovell, Smriti Agrawal, Jacques Zaneveld, Richard E Link
OBJECTIVE: To describe our experience using patient-specific tissue-like kidney models created with advanced three-dimensional (3D)-printing technology for preoperative planning and surgical rehearsal prior to robot-assisted laparoscopic partial nephrectomy (RALPN). PATIENTS AND METHODS: A feasibility study of 10 patients with solid renal masses who underwent RALPN after preoperative rehearsal using 3D-print kidney models. A single surgeon performed all surgical rehearsals and procedures...
November 10, 2016: BJU International
https://www.readbyqxmd.com/read/27847799/clinical-importance-of-congenital-anomalies-of-the-inferior-vena-cava-in-organ-procurement-surgery-from-a-deceased-donor-two-case-reports
#17
Mi-Hyeong Kim, Kang-Woong Jun, In-Sung Moon, Ji-Il Kim
Congenital anomalies of the inferior vena cava (IVC) are rare but important problems in living donors for kidney transplantation, especially in cases of a short left renal vein and accompanying vascular and urological anatomic variations. However, the clinical impacts of IVC anomalies in deceased donors have yet to be reported. The unexpected presence of an IVC in an unusual position poses challenges to surgeons and increases the risk of bleeding during organ removal. Accompanying vascular variations can cause unexpected bleeding and injury and therefore technical complications in procurement and subsequent implantation...
November 2016: Annals of Surgical Treatment and Research
https://www.readbyqxmd.com/read/27830490/soft-3d-printed-phantom-of-the-human-kidney-with-collecting-system
#18
Fabian Adams, Tian Qiu, Andrew Mark, Benjamin Fritz, Lena Kramer, Daniel Schlager, Ulrich Wetterauer, Arkadiusz Miernik, Peer Fischer
Organ models are used for planning and simulation of operations, developing new surgical instruments, and training purposes. There is a substantial demand for in vitro organ phantoms, especially in urological surgery. Animal models and existing simulator systems poorly mimic the detailed morphology and the physical properties of human organs. In this paper, we report a novel fabrication process to make a human kidney phantom with realistic anatomical structures and physical properties. The detailed anatomical structure was directly acquired from high resolution CT data sets of human cadaveric kidneys...
November 9, 2016: Annals of Biomedical Engineering
https://www.readbyqxmd.com/read/27829833/unusual-presentation-of-duplex-kidneys-ureteropelvic-junction-obstruction
#19
Cemile Başdaş, Süleyman Çelebi, Seyithan Özaydın, Birgül Karaaslan, Elmas Reyhan Alim, Ünal Güvenç, Serdar Sander
Aim. Ureteropelvic junction obstruction (UPJO) is rarely associated with a duplex collecting system. We review this unusual anomaly in terms of presentation, diagnostic evaluation, and surgical management. Method. We retrospectively reviewed the medical records of patients diagnosed with a duplex system with UPJO. Result. Sixteen patients (6 girls, 10 boys) with 18 moieties were treated surgically and four patients were treated conservatively. The median age at surgery was two years (range, 2 months to 7 years)...
2016: Advances in Urology
https://www.readbyqxmd.com/read/27811161/seventy-six-year-old-woman-with-an-unusual-anatomy-of-the-left-ureter
#20
George A Demetriou, Sohan Perera, Constantine Halkias, Shwan Ahmed
We present a case of a 76-year-old woman, who attended with features suggestive of renal colic; however on imaging, she was found to have a right pelvic kidney and a left-sided uretero-sciatic hernia (USH), identified on CT urography (CT urogram). She was managed conservatively as she had a normal renal function and reported no symptoms in follow-up appointments. USH are rare hernias, where the ureter herniates through the sciatic foramen. Patients might present with sepsis in which case they require emergency stenting either anterograde or retrograde or with pain in which a less urgent approach can be followed and plan for surgery...
November 3, 2016: BMJ Case Reports
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