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Kidney anatomy

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https://www.readbyqxmd.com/read/28077268/development-of-high-resolution-3d-hyperpolarized-carbon-13-mr-molecular-imaging-techniques
#1
Eugene Milshteyn, Cornelius von Morze, Galen D Reed, Hong Shang, Peter J Shin, Zihan Zhu, Hsin-Yu Chen, Robert Bok, Andrei Goga, John Kurhanewicz, Peder E Z Larson, Daniel B Vigneron
The goal of this project was to develop and apply techniques for T2 mapping and 3D high resolution (1.5mm isotropic; 0.003cm(3)) (13)C imaging of hyperpolarized (HP) probes [1-(13)C]lactate, [1-(13)C]pyruvate, [2-(13)C]pyruvate, and [(13)C,(15)N2]urea in vivo. A specialized 2D bSSFP sequence was implemented on a clinical 3T scanner and used to obtain the first high resolution T2 maps of these different hyperpolarized compounds in both rats and tumor-bearing mice. These maps were first used to optimize timings for highest SNR for single time-point 3D bSSFP acquisitions with a 1...
January 7, 2017: Magnetic Resonance Imaging
https://www.readbyqxmd.com/read/28048032/su-f-j-63-abdominal-diameter-changes-in-children-during-volumetric-modulated-arc-therapy-vmat-is-re-planning-needed
#2
F Guerreiro, G Janssens, E Seravalli, B Raaymakers
PURPOSE: To investigate the dosimetric impact of daily changes in patient's diameter, due to weight gain/loss and air in the bowel, based on CBCT information during radiotherapy treatment of pediatric abdominal tumors. METHODS: 10 pediatric patients with neuroblastoma (n=6) and Wilms' (n=4) tumors were included. Available CBCTs were affinely registered to the planning CT for daily set-up variations corrections. A density override approach assigning air-density to the random air pockets and water-density to the remaining anatomy was used to determine the CBCT and CT dose...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047839/th-cd-206-08-an-anthropopathic-deformable-phantom-for-geometric-and-dose-accumulation-accuracy-validation-of-deformable-image-registration
#3
Y Liao, H Chen, J Chen, X Gu, X Zhen, L Zhou
PURPOSE: To design and construct a three-dimensional (3D) anthropopathic abdominal phantom for evaluating deformable image registration (DIR) accuracy on images and dose deformation in adaptive radiation therapy (ART). METHOD: Organ moulds, including liver, kidney, spleen, stomach, vertebra and two metastasis tumors, are 3D printed using the contours from an ovarian cancer patient. The organ moulds are molded with deformable gels that made of different mixtures of polyvinyl chloride (PVC) and the softener dioctyl terephthalate...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047024/su-d-207a-07-the-effects-of-inter-cycle-respiratory-motion-variation-on-dose-accumulation-in-single-fraction-mr-guided-sbrt-treatment-of-renal-cell-carcinoma
#4
B Stemkens, M Glitzner, C Kontaxis, B Denis de Senneville, F Prins, Spm Crijns, L Kerkmeijer, J Lagendijk, Cat van den Berg, Rhn Tijssen
PURPOSE: To assess the dose deposition in simulated single-fraction MR-Linac treatments of renal cell carcinoma, when inter-cycle respiratory motion variation is taken into account using online MRI. METHODS: Three motion characterization methods, with increasing complexity, were compared to evaluate the effect of inter-cycle motion variation and drifts on the accumulated dose for an SBRT kidney MR-Linac treatment: 1) STATIC, in which static anatomy was assumed, 2) AVG-RESP, in which 4D-MRI phase-volumes were time-weighted, based on the respiratory phase and 3) PCA, in which 3D volumes were generated using a PCA-model, enabling the detection of inter-cycle variations and drifts...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28011754/logic-programming-to-infer-complex-rna-expression-patterns-from-rna-seq-data
#5
Tyler Weirick, Giuseppe Militello, Yuliya Ponomareva, David John, Claudia Döring, Stefanie Dimmeler, Shizuka Uchida
To meet the increasing demand in the field, numerous long noncoding RNA (lncRNA) databases are available. Given many lncRNAs are specifically expressed in certain cell types and/or time-dependent manners, most lncRNA databases fall short of providing such profiles. We developed a strategy using logic programming to handle the complex organization of organs, their tissues and cell types as well as gender and developmental time points. To showcase this strategy, we introduce 'RenalDB' (http://renaldb.uni-frankfurt...
December 22, 2016: Briefings in Bioinformatics
https://www.readbyqxmd.com/read/28000646/renal-cell-carcinoma-in-a-horseshoe-kidney-report-of-a-rare-disease
#6
Kehinde Habeeb Tijani, Rufus Wale Ojewola, Dubem E Orakwe, Abisola E Oliyide
A horseshoe kidney (HSK) is the most common congenital renal fusion anomaly. HSKs are more likely than normal kidneys to have associated problems of stones, ureteropelvic junction obstruction, stasis and infection. However, they do not have an increased incidence of renal cell carcinoma when compared to normal kidneys. Due to its rarity, accurate diagnosis may be difficult. Of similar significance is the fact that problems may arise during surgery on these kidneys due to altered anatomy and aberrant blood supply...
October 2016: Nigerian Postgraduate Medical Journal
https://www.readbyqxmd.com/read/27986484/a-comparison-of-brachial-artery-brachial-vein-arteriovenous-fistulas-with-arteriovenous-grafts-in-patients-with-poor-superficial-venous-anatomy
#7
Xuan-Binh D Pham, Jerry J Kim, Ezinne J Ihenachor, Aaron B Parrish, Jenny D Bleck, Amy H Kaji, Matthew C Koopmann, Christian de Virgilio
OBJECTIVE: The autogenous arteriovenous fistula (AVF) has been shown to be superior to the arteriovenous graft (AVG) with respect to cost, complications, and primary patency. Therefore, the National Kidney Foundation Disease Outcomes Quality Initiative guidelines recommend reserving AVGs for patients who do not have adequate superficial venous anatomy to support AVF placement. The brachial artery-brachial vein arteriovenous fistula (BVAVF) has emerged as an autologous last-effort alternative...
December 13, 2016: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/27885585/the-conundrums-of-chronic-kidney-disease-and-aging
#8
REVIEW
Richard J Glassock, Aleksandar Denic, Andrew D Rule
Chronic kidney disease (CKD), as presently defined, is a common disorder. Aging is a nearly universal phenomenon that can affect renal anatomy and function, but at variable rates in individuals. Loss of nephrons and a decline in glomerular filtration rate (GFR) is a characteristic of normal aging, called renal senescence. Using fixed and absolute thresholds for defining CKD on the basis of GFR for all ages may lead to diagnostic uncertainty (a conundrum) in both young and older subjects. This brief review will consider the physiological and anatomical changes of the kidney occurring in the process of normal renal senescence focusing on GFR and will examine the relevance of these observation for the diagnosis of CKD using GFR as the distinguishing parameter...
November 25, 2016: Journal of Nephrology
https://www.readbyqxmd.com/read/27862866/utility-of-patient-specific-silicone-renal-models-for-planning-and-rehearsal-of-complex-tumour-resections-prior-to-robot-assisted-laparoscopic-partial-nephrectomy
#9
Friedrich-Carl von Rundstedt, Jason M Scovell, Smriti Agrawal, Jacques Zaneveld, Richard E Link
OBJECTIVE: To describe our experience using patient-specific tissue-like kidney models created with advanced three-dimensional (3D)-printing technology for preoperative planning and surgical rehearsal prior to robot-assisted laparoscopic partial nephrectomy (RALPN). PATIENTS AND METHODS: A feasibility study of 10 patients with solid renal masses who underwent RALPN after preoperative rehearsal using 3D-print kidney models. A single surgeon performed all surgical rehearsals and procedures...
November 10, 2016: BJU International
https://www.readbyqxmd.com/read/27847799/clinical-importance-of-congenital-anomalies-of-the-inferior-vena-cava-in-organ-procurement-surgery-from-a-deceased-donor-two-case-reports
#10
Mi-Hyeong Kim, Kang-Woong Jun, In-Sung Moon, Ji-Il Kim
Congenital anomalies of the inferior vena cava (IVC) are rare but important problems in living donors for kidney transplantation, especially in cases of a short left renal vein and accompanying vascular and urological anatomic variations. However, the clinical impacts of IVC anomalies in deceased donors have yet to be reported. The unexpected presence of an IVC in an unusual position poses challenges to surgeons and increases the risk of bleeding during organ removal. Accompanying vascular variations can cause unexpected bleeding and injury and therefore technical complications in procurement and subsequent implantation...
November 2016: Annals of Surgical Treatment and Research
https://www.readbyqxmd.com/read/27830490/soft-3d-printed-phantom-of-the-human-kidney-with-collecting-system
#11
Fabian Adams, Tian Qiu, Andrew Mark, Benjamin Fritz, Lena Kramer, Daniel Schlager, Ulrich Wetterauer, Arkadiusz Miernik, Peer Fischer
Organ models are used for planning and simulation of operations, developing new surgical instruments, and training purposes. There is a substantial demand for in vitro organ phantoms, especially in urological surgery. Animal models and existing simulator systems poorly mimic the detailed morphology and the physical properties of human organs. In this paper, we report a novel fabrication process to make a human kidney phantom with realistic anatomical structures and physical properties. The detailed anatomical structure was directly acquired from high resolution CT data sets of human cadaveric kidneys...
November 9, 2016: Annals of Biomedical Engineering
https://www.readbyqxmd.com/read/27829833/unusual-presentation-of-duplex-kidneys-ureteropelvic-junction-obstruction
#12
Cemile Başdaş, Süleyman Çelebi, Seyithan Özaydın, Birgül Karaaslan, Elmas Reyhan Alim, Ünal Güvenç, Serdar Sander
Aim. Ureteropelvic junction obstruction (UPJO) is rarely associated with a duplex collecting system. We review this unusual anomaly in terms of presentation, diagnostic evaluation, and surgical management. Method. We retrospectively reviewed the medical records of patients diagnosed with a duplex system with UPJO. Result. Sixteen patients (6 girls, 10 boys) with 18 moieties were treated surgically and four patients were treated conservatively. The median age at surgery was two years (range, 2 months to 7 years)...
2016: Advances in Urology
https://www.readbyqxmd.com/read/27811161/seventy-six-year-old-woman-with-an-unusual-anatomy-of-the-left-ureter
#13
George A Demetriou, Sohan Perera, Constantine Halkias, Shwan Ahmed
We present a case of a 76-year-old woman, who attended with features suggestive of renal colic; however on imaging, she was found to have a right pelvic kidney and a left-sided uretero-sciatic hernia (USH), identified on CT urography (CT urogram). She was managed conservatively as she had a normal renal function and reported no symptoms in follow-up appointments. USH are rare hernias, where the ureter herniates through the sciatic foramen. Patients might present with sepsis in which case they require emergency stenting either anterograde or retrograde or with pain in which a less urgent approach can be followed and plan for surgery...
November 3, 2016: BMJ Case Reports
https://www.readbyqxmd.com/read/27796600/robust-augmented-reality-registration-method-for-localization-of-solid-organs-tumors-using-ct-derived-virtual-biomechanical-model-and-fluorescent-fiducials
#14
Seong-Ho Kong, Nazim Haouchine, Renato Soares, Andrey Klymchenko, Bohdan Andreiuk, Bruno Marques, Galyna Shabat, Thierry Piechaud, Michele Diana, Stéphane Cotin, Jacques Marescaux
BACKGROUND: Augmented reality (AR) is the fusion of computer-generated and real-time images. AR can be used in surgery as a navigation tool, by creating a patient-specific virtual model through 3D software manipulation of DICOM imaging (e.g., CT scan). The virtual model can be superimposed to real-time images enabling transparency visualization of internal anatomy and accurate localization of tumors. However, the 3D model is rigid and does not take into account inner structures' deformations...
October 27, 2016: Surgical Endoscopy
https://www.readbyqxmd.com/read/27795549/nanomedicines-for-renal-disease-current-status-and-future-applications
#15
REVIEW
Nazila Kamaly, John C He, Dennis A Ausiello, Omid C Farokhzad
Treatment and management of kidney disease currently presents an enormous global burden, and the application of nanotechnology principles to renal disease therapy, although still at an early stage, has profound transformative potential. The increasing translation of nanomedicines to the clinic, alongside research efforts in tissue regeneration and organ-on-a-chip investigations, are likely to provide novel solutions to treat kidney diseases. Our understanding of renal anatomy and of how the biological and physico-chemical properties of nanomedicines (the combination of a nanocarrier and a drug) influence their interactions with renal tissues has improved dramatically...
December 2016: Nature Reviews. Nephrology
https://www.readbyqxmd.com/read/27778490/robotic-pyelolithotomy-in-a-congenital-pelvic-kidney-side-docking-and-robotic-prostatectomy-port-site-approach
#16
Rawan Al-Yousef, Ahmad Almarzouq, Saad Aldousari
INTRODUCTION AND OBJECTIVES: Ectopic pelvic kidneys with renal stones are challenging to treat. We report our experience in managing a case of ectopic pelvic kidney with a pelvic stone by robotic pyelolithotomy after failure of flexible ure¬teroscopy. MATERIALS AND METHODS: A 46-year old male with 2 months history of vague lower abdominal pain was found to have on Computed Tomography scan a left ectopic pelvic kidney with a 12mm stone in an anomalous renal pelvis...
October 20, 2016: International Braz J Urol: Official Journal of the Brazilian Society of Urology
https://www.readbyqxmd.com/read/27770469/toward-imaging-the-body-at-10-5-tesla
#17
M Arcan Ertürk, Xiaoping Wu, Yiğitcan Eryaman, Pierre-François Van de Moortele, Edward J Auerbach, Russell L Lagore, Lance DelaBarre, J Thomas Vaughan, Kâmil Uğurbil, Gregor Adriany, Gregory J Metzger
PURPOSE: To explore the potential of performing body imaging at 10.5 Tesla (T) compared with 7.0T through evaluating the transmit/receive performance of similarly configured dipole antenna arrays. METHODS: Fractionated dipole antenna elements for 10.5T body imaging were designed and evaluated using numerical simulations. Transmit performance of antenna arrays inside the prostate, kidneys and heart were investigated and compared with those at 7.0T using both phase-only radiofrequency (RF) shimming and multi-spoke pulses...
January 2017: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/27770429/radiation-dosimetry-of-the-%C3%AE-4%C3%AE-2-nicotinic-receptor-ligand-18-f-flubatine-comparing-preclinical-pet-mri-and-pet-ct-to-first-in-human-pet-ct-results
#18
Mathias Kranz, Bernhard Sattler, Solveig Tiepolt, Stephan Wilke, Winnie Deuther-Conrad, Cornelius K Donat, Steffen Fischer, Marianne Patt, Andreas Schildan, Jörg Patt, René Smits, Alexander Hoepping, Jörg Steinbach, Osama Sabri, Peter Brust
BACKGROUND: Both enantiomers of [(18)F]flubatine are new radioligands for neuroimaging of α4β2 nicotinic acetylcholine receptors with positron emission tomography (PET) exhibiting promising pharmacokinetics which makes them attractive for different clinical questions. In a previous preclinical study, the main advantage of (+)-[(18)F]flubatine compared to (-)-[(18)F]flubatine was its higher binding affinity suggesting that (+)-[(18)F]flubatine might be able to detect also slight reductions of α4β2 nAChRs and could be more sensitive than (-)-[(18)F]flubatine in early stages of Alzheimer's disease...
December 2016: EJNMMI Physics
https://www.readbyqxmd.com/read/27751879/can-preeclampsia-be-considered-a-renal-compartment-syndrome-a-hypothesis-and-analysis-of-the-literature
#19
David G Reuter, Yuk Law, Wayne C Levy, Stephen P Seslar, R Eugene Zierler, Mark Ferguson, James Chattra, Tim McQuinn, Lenna L Liu, Mark Terry, Patricia S Coffey, Jane A Dimer, Coral Hanevold, Joseph T Flynn, F Bruder Stapleton
The morbidity and mortality associated with preeclampsia is staggering. The physiology of the Page kidney, a condition in which increased intrarenal pressure causes hypertension, appears to provide a unifying framework to explain the complex pathophysiology. Page kidney hypertension is renin-mediated acutely and ischemia-mediated chronically. Renal venous outflow obstruction also causes a Page kidney phenomenon, providing a hypothesis for the increased vulnerability of a subset of women who have what we are hypothesizing is a "renal compartment syndrome" due to inadequate ipsilateral collateral renal venous circulation consistent with well-known variation in normal venous anatomy...
September 15, 2016: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/27731512/retroperitoneal-laparoscopy-in-dogs-access-technique-working-space-and-surgical-anatomy
#20
Junemoe Jeong, Jonghyeok Ko, Hyunjoo Lim, Oh-Kyeong Kweon, Wan Hee Kim
OBJECTIVE: To develop and describe a laparoscopic retroperitoneal access technique, investigate working space establishment, and describe the surgical anatomy in the retroperitoneal space as an initial step for clinical application of retroperitoneal laparoscopy in dogs. STUDY DESIGN: Cadaveric and experimental study. ANIMALS: Cadaveric (n=8) and healthy (n=6) adult dogs. METHODS: The retroperitoneal access technique was developed in 3 cadavers based on the human technique and transperitoneal observation...
November 2016: Veterinary Surgery: VS
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