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Kidney anatomy

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https://www.readbyqxmd.com/read/28912007/adventitial-adipogenic-degeneration-is-an-unidentified-contributor-to-aortic-wall-weakening-in-the-abdominal-aortic-aneurysm
#1
Stefan A Doderer, Gabor Gäbel, Vivianne B C Kokje, Bernd H Northoff, Lesca M Holdt, Jaap F Hamming, Jan H N Lindeman
OBJECTIVE: The processes driving human abdominal aortic aneurysm (AAA) progression are not fully understood. Although antiinflammatory and proteolytic strategies effectively quench aneurysm progression in preclinical models, so far all clinical interventions failed. These observations hint at an incomplete understanding of the processes involved in AAA progression and rupture. Interestingly, strong clinical and molecular associations exist between popliteal artery aneurysms (PAAs) and AAAs; however, PAAs have an extremely low propensity to rupture...
September 11, 2017: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/28879095/unilateral-complete-agenesis-of-mesonephric-duct-derivatives-in-an-82-year-old-male-cadaver-embryology-anatomy-and-clinical-considerations
#2
David G Darcy, Morgen Yao-Cohen, Todd R Olson, Sherry A Downie
Development of urogenital anatomy in the human fetus is the result of a complex interplay between multiple different tissues. The time course of development is well documented and the morphologic outcomes of insults at various time points during development are predictable. We present a cadaveric case of unilateral agenesis of the left kidney, ureter, bladder hemitrigone, ureteric opening, seminal vesicle, vas deferens, and epididymis. Failure of development of the mesonephric duct early during embryogenesis, likely between the third and fifth week, caused ipsilateral urogenital organ agenesis...
November 2017: Urology Case Reports
https://www.readbyqxmd.com/read/28869203/nephron-sparing-suture-of-renal-parenchyma-after-partial-nephrectomy-which-technique-to-go-for-some-best-practices
#3
Francesco Porpiglia, Riccardo Bertolo, Daniele Amparore, Cristian Fiori
The quantity of the preserved parenchyma after partial nephrectomy is the result of interplay among various factors: the unmodifiable preoperative quality of the renal parenchyma and some technical modifiable aspects. Among the modifiable factors able to influence the quantity, the suture technique has gained paramount importance. Indeed, nowadays there is a consensus suggesting that one of the main predictors of the ultimate renal function is the minimal parenchymal volume loss: this is the sum of the healthy parenchyma excised with the tumour and the portion of the parenchyma devascularised by the renorrhaphy...
August 28, 2017: European Urology Focus
https://www.readbyqxmd.com/read/28816298/-multiple-endoscopy-for-the-treatment-of-upper-urinary-tract-calculi-following-ileal-conduit-a-case-report-and-literature-review
#4
B Wang, J F Ye, L Zhao, H Bi, J Lu, L L Ma
Upper urinary tract calculi with infection is a quite difficult acute urologic emergency. And what is more, upper urinary tract obstruction after radical cystectomy following urinary diversion may be fatal in the vulnerable patients with this kind of situation. Postoperative anatomy and other factors affect the upper urinary tract calculi, and urinary tract infection greatly increased the risk. But it is particularly difficult to handle with patients with poor general condition and septic shock treatment, so how to optimize the selection program is worth further studying...
August 18, 2017: Beijing da Xue Xue Bao. Yi Xue Ban, Journal of Peking University. Health Sciences
https://www.readbyqxmd.com/read/28768757/optimized-screening-of-coronary-artery-disease-with-invasive-coronary-angiography-and-ad-hoc-percutaneous-coronary-intervention-during-transcatheter-aortic-valve-replacement
#5
Marco Barbanti, Denise Todaro, Giuliano Costa, Gerlando Pilato, Andrea Picci, Simona Gulino, Piera Capranzano, Ketty La Spina, Emanuela Di Simone, Paolo D'Arrigo, Wanda Deste, Antonino Indelicato, Stefano Cannata, Daniela Giannazzo, Sebastiano Immè, Claudia Tamburino, Martina Patanè, Sergio Buccheri, Davide Capodanno, Carmelo Sgroi, Corrado Tamburino
BACKGROUND: We sought to describe an optimized approach to coronary artery disease (CAD) screening and management in patients undergoing transcatheter aortic valve replacement (TAVR). METHODS AND RESULTS: When invasive coronary angiography showed CAD, the treatment strategy and completeness of revascularization was determined based on coronary anatomy. TAVR was performed in the same setting if percutaneous coronary intervention (PCI) was uncomplicated; otherwise TAVR was postponed...
August 2017: Circulation. Cardiovascular Interventions
https://www.readbyqxmd.com/read/28744072/multimodality-imaging-spectrum-of-complications-of-horseshoe-kidney
#6
Hardik U Shah, Vijayanadh Ojili
Horseshoe kidney is the most common congenital renal fusion anomaly with an incidence of 1 in 400-600 individuals. The most common type is fusion at the lower poles seen in greater than 90% of the cases, with the rest depicting fusion at the upper poles, resulting in an inverted horseshoe kidney. Embryologically, there are two theories hypothesizing the genesis of horseshoe kidney - mechanical fusion theory and teratogenic event theory. As an entity, horseshoe kidney is an association of two anatomic anomalies, namely, ectopia and malrotation...
April 2017: Indian Journal of Radiology & Imaging
https://www.readbyqxmd.com/read/28706756/impact-of-vital-dyes-on-cell-viability-and-transduction-efficiency-of-aav-vectors-used-in-retinal-gene-therapy-surgery-an-in-vitro-and-in-vivo-analysis
#7
Anna P Salvetti, Maria I Patrício, Alun R Barnard, Harry O Orlans, Doron G Hickey, Robert E MacLaren
PURPOSE: Treatment of inherited retinal degenerations using adeno-associated viral (AAV) vectors involves delivery by subretinal injection. In the latter stages, alteration of normal anatomy may cause difficulty in visualizing the retinotomy, retinal detachment extension, and vector diffusion. Vital dyes may be useful surgical adjuncts, but their safety and impact on AAV transduction are largely unknown. METHODS: The effects of Sodium Fluorescein (SF), Membrane Blue (MB), and Membrane Blue Dual (DB) at a range of dilutions were assessed on human embryonic kidney cells in vitro using an AAV2-green fluorescent protein (GFP) reporter at different multiplicities of infection...
July 2017: Translational Vision Science & Technology
https://www.readbyqxmd.com/read/28696514/modulation-of-lateral-positions-of-bragg-peaks-via-magnetic-fields-inside-cancer-patients-towards-magnetic-field-modulated-proton-therapy
#8
Wencheng Shao, Xiaobin Tang, Yanling Bai, Changran Geng, Diyun Shu, Chunhui Gong, Da Chen
PURPOSE: This work investigated whether the Bragg peak (BP) positions of proton beams can be modulated to produce uniform doses and cover a tumor under the magnetic fields inside cancer patients, and whether magnetic field modulated proton therapy (MMPT) is effective in vital organ protection. METHODS: The authors initially constructed an ideal water phantom comprising a central tumor surrounded by cuboid organ regions using GEANT4. Second, we designed the proton beams passing through the gap between two adjacent organ regions during beam configuration...
July 11, 2017: Medical Physics
https://www.readbyqxmd.com/read/28664233/endovascular-treatment-of-wide-necked-visceral-artery-aneurysms-using-the-neurovascular-comaneci-neck-bridging-device-a-technical-report
#9
Julian Maingard, Hong Kuan Kok, Emma Phelan, Caitriona Logan, Dinesh Ranatunga, Duncan Mark Brooks, Ronil V Chandra, Michael J Lee, Hamed Asadi
INTRODUCTION: Visceral and renal artery aneurysms (VRAAs) are an uncommon clinical entity but carry a risk of rupture with associated morbidity and mortality. The rupture risk is particularly high when the aneurysms are large, of unfavourable morphology or in the setting of pregnancy and perioperative period. Endovascular approaches are now first line in the treatment of VRAA, but conventional techniques may be ineffective in excluding aneurysms with unfavourable anatomy such as those with wide necks or at arterial bifurcation points...
June 29, 2017: Cardiovascular and Interventional Radiology
https://www.readbyqxmd.com/read/28660086/successful-use-of-ectopic-pelvic-kidney-for-living-related-donation-technical-aspects-and-literature-review
#10
R C Minnee, H J A N Kimenai, J van de Wetering, J N M Ijzermans
Ectopic pelvic kidneys can provide an additional source of organs for transplantation. They are often excluded from donation in living donation programs mainly due to aberrant vascular and urinary anatomies. We present a donor with an ectopic left kidney, who successfully donated his kidney. The use of ectopic pelvic kidney for living kidney transplantation is a highly demanding surgical procedure but after extensive preoperative investigation in high volume centers with surgical expertise in vascular reconstruction and access surgery, ectopic pelvic kidneys should not be a contraindication for donation and should be considered as a viable option...
2017: Case Reports in Transplantation
https://www.readbyqxmd.com/read/28659992/analysis-of-urine-flow-in-three-different-ureter-models
#11
Kyung-Wuk Kim, Young Ho Choi, Seung Bae Lee, Yasutaka Baba, Hyoung-Ho Kim, Sang-Ho Suh
The ureter provides a way for urine to flow from the kidney to the bladder. Peristalsis in the ureter partially forces the urine flow, along with hydrostatic pressure. Ureteral diseases and a double J stent, which is commonly inserted in a ureteral stenosis or occlusion, disturb normal peristalsis. Ineffective or no peristalsis could make the contour of the ureter a tube, a funnel, or a combination of the two. In this study, we investigated urine flow in the abnormal situation. We made three different, curved tubular, funnel-shaped, and undulated ureter models that were based on human anatomy...
2017: Computational and Mathematical Methods in Medicine
https://www.readbyqxmd.com/read/28653304/the-impact-of-pelvicalyceal-anatomy-on-the-stone-formation-in-patients-with-lower-pole-renal-stones
#12
Krzysztof Balawender, Stanisław Orkisz
BACKGROUND: The aim of our study was to determine whether various anatomic factors constitute a predisposition to a lower pole renal stones. METHODS: We analysed the computed tomography (CT) urography of 75 patients with a single lower pole stone. Measurements were taken of the infundibulopelvic angle (IPA),infundibular width (IW), infundibular length (IL) and calyceopelvic height (CPH). RESULTS: The mean patient age was 50 years (range 17-79)...
June 27, 2017: Folia Morphologica (Warsz)
https://www.readbyqxmd.com/read/28648650/planning-execution-and-follow-up-for-endovascular-aortic-aneurysm-repair-using-a-highly-restrictive-iodinated-contrast-protocol-in-patients-with-severe-renal-disease
#13
E Gallitto, G L Faggioli, M Gargiulo, A Freyrie, R Pini, C Mascoli, S Ancetti, V Vento, A Stella
BACKGROUND: The cumulative amount of iodinated-contrast-medium necessary for EVAR planning, operative procedure and subsequent follow-up is a threat for the onset of end stage renal disease in patients with pre-operative impaired kidney function. Purpose of this study is to describe a mini-invasive approach aimed to minimize the exposure of these patients to iodinated-contrast-medium and the subsequent risk of renal function worsening. METHODS: From 2012 to 2015, all patients with abdominal aortic aneurysm (AAA) at high-surgical risk and fit for standard endovascular repair (simple aortic-iliac anatomy: proximal and distal neck length ≥15mm, no severe angulation), underwent EVAR through the following "near-zero contrast" approach, if their glomerular filtration rate (GFR) was <30 mL/min: pre-operative planning was performed by non-contrast enhanced computed tomography (CT) and duplex-ultrasound (DU); the origin of renal/hypogastric arteries and aortic bifurcation was evaluated and matched with vertebral bone landmarks and the endograft deployed accordingly, using < 20cc of isotonic iodinate-contrast-medium and contrast-enhancement-DU (CEUS)...
June 22, 2017: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/28648301/associations-of-early-kidney-disease-with-brain-magnetic-resonance-imaging-and-cognitive-function-in-african-americans-with-type-2-diabetes-mellitus
#14
Barry I Freedman, Kaycee M Sink, Christina E Hugenschmidt, Timothy M Hughes, Jeff D Williamson, Christopher T Whitlow, Nicholette D Palmer, Michael E Miller, Laura C Lovato, Jianzhao Xu, S Carrie Smith, Lenore J Launer, Joshua I Barzilay, Robert M Cohen, Mark D Sullivan, R Nick Bryan, Benjamin C Wagner, Donald W Bowden, Joseph A Maldjian, Jasmin Divers
BACKGROUND: Relationships between early kidney disease, neurocognitive function, and brain anatomy are poorly defined in African Americans with type 2 diabetes mellitus (T2DM). STUDY DESIGN: Cross-sectional associations were assessed between cerebral anatomy and cognitive performance with estimated glomerular filtration rate (eGFR) and urine albumin-creatinine ratio (UACR) in African Americans with T2DM. SETTING & PARTICIPANTS: African Americans with cognitive testing and cerebral magnetic resonance imaging (MRI) in the African American-Diabetes Heart Study Memory in Diabetes (AA-DHS MIND; n=512; 480 with MRI) and Action to Control Cardiovascular Risk in Diabetes (ACCORD) MIND (n=484; 104 with MRI) studies...
June 22, 2017: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/28632265/3d-printed-conformal-microfluidics-for-isolation-and-profiling-of-biomarkers-from-whole-organs
#15
Manjot Singh, Yuxin Tong, Kelly Webster, Ellen Cesewski, Alexander P Haring, Sahil Laheri, Bill Carswell, Timothy J O'Brien, Charles H Aardema, Ryan S Senger, John L Robertson, Blake N Johnson
The ability to interface microfluidic devices with native complex biological architectures, such as whole organs, has the potential to shift the paradigm for the study and analysis of biological tissue. Here, we show 3D printing can be used to fabricate bio-inspired conformal microfluidic devices that directly interface with the surface of whole organs. Structured-light scanning techniques enabled the 3D topographical matching of microfluidic device geometry to porcine kidney anatomy. Our studies show molecular species are spontaneously transferred from the organ cortex to the conformal microfluidic device in the presence of fluid flow through the organ-conforming microchannel...
July 25, 2017: Lab on a Chip
https://www.readbyqxmd.com/read/28592391/long-term-fate-of-the-upper-tracts-following-complete-primary-repair-of-bladder-exstrophy
#16
Jonathan S Ellison, Jennifer Ahn, Margarett Shnorhavorian, Richard Grady, Paul A Merguerian
INTRODUCTION: Complete primary repair of bladder exstrophy (CPRE) is widely used for classic bladder exstrophy (CBE) closure. Long-term renal function with or without dilation in these patients is poorly characterized and may be impacted by bladder storage parameters or recurrent urinary tract infections (UTIs). OBJECTIVE: We sought to assess our long-term experience with CPRE and investigate factors that may influence upper-tract deterioration. STUDY DESIGN: A retrospective review of patients at our institution with CBE undergoing CPRE from 1990 to 2015 was performed...
May 17, 2017: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/28559176/results-from-multiple-prospective-single-center-clinical-trials-of-the-off-the-shelf-p-branch-fenestrated-stent-graft
#17
Mark A Farber, Matthew J Eagleton, Tara M Mastracci, James F McKinsey, Raghuveer Vallabhaneni, Björn Sonesson, Nuno Dias, Timothy Resch
OBJECTIVE: The purpose of this study was to report prospective data of an off-the-shelf fenestrated endograft (Zenith p-Branch; Cook Medical, Bloomington, Ind) from four centers for the treatment of patients with pararenal abdominal aortic aneurysms. METHODS: Data were combined from four single-center investigational studies conducted in the United States and Europe. The p-Branch endograft consists of a proximal off-the-shelf component incorporating a scallop for the celiac artery, a superior mesenteric artery fenestration, and two conical pivot fenestrations to preserve flow to the renal vessels...
May 27, 2017: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/28557332/impact-of-contrast-exposure-from-computed-tomography-angiography-on-acute-kidney-injury-after-neonatal-cardiopulmonary-bypass-surgery
#18
Waldemar F Carlo, Steven T Clark, Santiago Borasino, Jeffrey A Alten
OBJECTIVE: Acute kidney injury (AKI) is a frequent complication after cardiopulmonary bypass (CBP) for cardiac surgery in neonates. It is unclear if exposure to computed tomography angiography (CTA) in the preoperative period increases the risk of AKI. We hypothesized a short interval between CTA and CPB surgery would be associated with higher rates of AKI in infants. DESIGN: In this single center retrospective review of patients between 2012 and 2015, neonates less than one month old were analyzed if they had CTA prior to cardiac surgery with CPB...
May 30, 2017: Congenital Heart Disease
https://www.readbyqxmd.com/read/28544435/solid-renal-masses-in-transplanted-allograft-kidneys-a-closer-look-at-the-epidemiology-and-management
#19
REVIEW
J J Griffith, K A Amin, N Waingankar, S M Lerner, V Delaney, S A Ames, K Badani, M A Palese, R Mehrazin
The objective of this review is to explore the available literature on solid renal masses (SRMs) in transplant allograft kidneys to better understand the epidemiology and management of these tumors. A literature review using PubMed was performed according to the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) methodology. Fifty-six relevant studies were identified from 1988 to 2015. A total of 174 SRMs in 163 patients were identified, with a mean tumor size of 2.75 cm (range 0.5-9...
May 19, 2017: American Journal of Transplantation
https://www.readbyqxmd.com/read/28540840/living-donor-kidney-transplant-in-a-patient-with-type-b-mayer-rokitansky-k%C3%A3-ster-hauser-syndrome-reconstructed-vagina-and-abnormal-pelvic-vessels-a-case-report
#20
Mariarosaria Campise, Mariano Ferraresso, Evaldo Favi, Claudio Beretta, Caterina Colico, Piergiorgio Messa
Mayer-Rokitansky-Küster-Hauser syndrome is a rare disorder consisting of vaginal aplasia and other müllerian duct abnormalities. Urinary tract malfor-mations possibly leading to renal failure are also common. For these patients, kidney transplant remains the best option. However, aberrant anatomy and scarring from previous operations may actually preclude successful implantation of the graft. In this setting, careful pretransplant evaluation with high-resolution imaging studies and multidisciplinary planning are mandatory...
May 22, 2017: Experimental and Clinical Transplantation
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