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Kidney anatomy

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https://www.readbyqxmd.com/read/29149982/marrow-mesenchymal-stem-cells-effectively-reduce-histologic-changes-in-a-rat-model-of-chronic-renal-allograft-rejection
#1
P Yu, Z Wang, Y Liu, Z Xiao, Y Guo, M Li, M Zhao
BACKGROUND: Chronic allograft rejection remains as the leading cause of the chronic renal grafts loss post-transplantation. No therapy has been found really effective to prevent and treat chronic allograft rejection. Mesenchymal stem cells (MSCs) have characteristics of immunomodulation and are expected to be used for inducing graft immune tolerance in organ transplantation. We investigated the efficacy and safety of early infusion of donor-derived marrow MSCs in a rat model of chronic renal allograft rejection...
November 2017: Transplantation Proceedings
https://www.readbyqxmd.com/read/29149952/financial-impact-of-incidental-radiologic-findings-during-living-kidney-donor-evaluation
#2
A Mutneja, L Saling, M Yano, A Vijayan
Living kidney donor (LKD) transplantation is an important alternative for the end-stage renal disease population and is preferred due to superior outcomes when compared with dialysis or deceased donor transplantation. LKD evaluation includes a computed tomography angiogram (CTA) for assessment of renal and renovascular anatomy. Incidental nonrenal findings are frequently noted during the CTAs, and these may have variable clinical significance. These incidental findings lead to further testing, procedures, and referrals, which incur additional cost...
November 2017: Transplantation Proceedings
https://www.readbyqxmd.com/read/29145401/anatomically-specific-intratubular-and-interstitial-biominerals-in-the-human-renal-medullo-papillary-complex
#3
Ling Chen, Ryan S Hsi, Feifei Yang, Benjamin A Sherer, Marshall L Stoller, Sunita P Ho
Limited information exists on the anatomically-specific early stage events leading to clinically detectable mineral aggregates in the renal papilla. In this study, quantitative multiscale correlative maps of structural, elemental and biochemical properties of whole medullo-papillary complexes from human kidneys were developed. Correlative maps of properties specific to the uriniferous and vascular tubules using high-resolution X-ray computed tomography, scanning and transmission electron microscopy, energy dispersive X-ray spectroscopy, and immunolocalization of noncollagenous proteins (NCPs) along with their association with anatomy specific biominerals were obtained...
2017: PloS One
https://www.readbyqxmd.com/read/29119295/treatment-of-hip-fracture-of-pope-innocent-xii-by-marcello-malpighi-with-bed-rest
#4
REVIEW
Marco Bigoni, Giovanni Zatti, Nicolò Zanchi, Filippo Maria Anghilieri, Michele A Riva
Marcello Malpighi (1628-1694), who is referred to as the father of microscopical anatomy, histology, physiology and embryology was an Italian biologist and physician, well known for his discoveries on microscopical anatomy of kidney, circulating and lymphatic systems. As well as being a brilliant anatomist, Malpighi was also a valued physician so far as to became the personal physician of Pope Innocent XII (1615-1700). On 23 August 1691, one month after his election, the Pope fell to the ground hitting his left hip...
November 8, 2017: International Orthopaedics
https://www.readbyqxmd.com/read/29118534/pure-retroperitoneoscopic-donor-nephrectomy-in-duplication-of-inferior-vena-cava-a-series-of-four-cases
#5
Bipin Chandra Pal, Pranjal R Modi, Syed Jamal Rizvi, Rohit Chauhan, Suresh Kumar, Shruti P Gandhi, Vivek B Kute, Hargovind L Trivedi
Aim: Complex vascular anatomy poses a major challenge to the donor surgeon. Here, we have described the technical nuances in retroperitoneoscopic living donor nephrectomy for the left kidney in the situations of a rare vascular anomaly of duplication of inferior vena. Materials and Methods: Between September 2005 and June 2016, 1460 retroperitoneoscopic living donor nephrectomy were carried out in single surgical unit of our institution. Out of these four donors were found to have duplication of inferior vena cava (IVC)...
October 2017: Urology Annals
https://www.readbyqxmd.com/read/29114109/frequency-of-acccessory-renal-arteries-diagnosed-by-computerized-tomography
#6
Sabina Prevljak, Edin Prelevic, Salih Mesic, Odey Ali Abud, Spomenka Kristic, Sandra Vegar-Zubovic
Introduction: Accessory renal arteries play a significant role in kidney and abdominal aorta surgery, and renovascular hypertension. In the published literature, the frequency varies considerably, depending on the size of the sample, the method of examination and the ethnic group. Materials and Methods: The aim of this study is to determine the general frequency of accessory renal arteries, their frequency in relation to gender, the origin and the vascularization area, and to determine the differences in left-right and bilateral distribution...
September 2017: Acta Informatica Medica: AIM
https://www.readbyqxmd.com/read/29106471/kidney-function-modifies-the-selection-of-treatment-strategies-and-long-term-survival-in-stable-ischemic-heart-disease-insights-from-the-alberta-provincial-project-for-outcomes-assessment-in-coronary-heart-disease-approach-registry
#7
Jay S Shavadia, Danielle A Southern, Matthew T James, Robert C Welsh, Kevin R Bainey
Aims: Patients with chronic kidney disease (CKD) have been under-represented in stable ischemic heart disease (SIHD) trials despite their heightened risk of cardiovascular mortality. We examine associations between kidney disease, treatment selection, and long-term survival in patients with SIHD. Methods and Results: SIHD patients with angiographically significant stenosis (≥70%) were categorized by renal function (dialysis-dependent, severe CKD [eGFR<30], mild-moderate CKD [eGFR30-59] and no CKD [eGFR≥60]), and by treatment groups (revascularization ≤ 3 months of angiogram [CABG or PCI] versus medical therapy)...
November 2, 2017: European Heart Journal. Quality of Care & Clinical Outcomes
https://www.readbyqxmd.com/read/29102666/a-90-day-subchronic-gavage-toxicity-study-in-fischer-344-rats-with-3-methylfuran
#8
S Gill, M Kavanagh, W Cherry, C Bourque, D Caldwell, G Wang, G Bondy
A 90-day gavage study was conducted with 0.0, 0.02, 0.075, 0.25, 1.0 and 4.0 mg/kg bw/day dose groups of 3-methylfuran to identify a no-observed adverse effect level for hepatotoxicity and to characterize non-neoplastic effects including changes in gross anatomy, histopathology, clinical biochemistry and hematology. There were significant changes in the serum clinical biochemistry markers related to liver injury where males were more affected than the females for most parameters analysed. The serum liver injury marker γ-glutamyltransferase, alanine and aspartate aminotransferases were significantly increased in males in the 4...
November 1, 2017: Food and Chemical Toxicology
https://www.readbyqxmd.com/read/29078159/challenging-case-of-horseshoe-kidney-double-fracture
#9
Francesco Cortese, Pietro Fransvea, Roberto Marcello, Alessandra Saputelli, Luca Lepre, Aldo Gioffrè, Gabriele Sganga
INTRODUCTION: Renal injuries occur in 10% of blunt abdominal traumas, 7% of these occur in kidneys with congenital or acquired disorders. Trauma of horseshoe kidney is an uncommon finding. PRESENTATION OF A CASE: We present the case of 31 year-old caucasian man with no remarkable personal records, who was brought to our Trauma Unit soon after being involved in a motorcycle collision. A Contrast Enhanced - Multi Detector Computed Tomography (ce-MDCT) revealed a double disconnection of a horseshoe kidney...
October 10, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/29077866/are-there-any-relations-among-transplant-centre-volume-surgical-technique-and-anatomy-for-donor-graft-selection-ten-year-multicentric-italian-experience-on-mini-invasive-living-donor-nephrectomy
#10
Matteo Ravaioli, Enzo Capocasale, Lucrezia Furian, Vanessa De Pace, Maurizio Iaria, Gionata Spagnoletti, Maria Paola Salerno, Alessandro Giacomoni, Luciano De Carlis, Caterina Di Bella, Nguefouet Momo Rostand, Luigino Boschiero, Giovanni Pasquale, Andrea Bosio, Andrea Collini, Mario Carmellini, Andrea Airoldi, Gianmarco Bondonno, Pasquale Ditonno, Stefano Vittorio Impedovo, Claudio Beretta, Antenore Giussani, Carlo Socci, Danilo Carlo Parolini, Massimo Abelli, Elena Ticozzelli, Umberto Baccarani, Gian Luigi Adani, Flavia Caputo, Barbara Buscemi, Mauro Frongia, Andrea Solinas, Salvatore Gruttadauria, Marco Spada, Antonio Daniele Pinna, Jacopo Romagnoli
Background: Selection of the right or left living donor kidney for transplantation is influenced by many variables. In the present multi centric study including 21 Italian transplant centres, we evaluated whether centre volume or surgical technique may influence the selection process. Methods: Intra- and perioperative donor data, donor kidney function, and recipient and graft survival were collected among 693 mini-invasive living donor nephrectomies performed from 2002 to 2014...
October 25, 2017: Nephrology, Dialysis, Transplantation
https://www.readbyqxmd.com/read/29068584/hydronephrosis-in-the-course-of-ureteropelvic-junction-obstruction-an-underestimated-problem-current-opinions-on-the-pathogenesis-diagnosis-and-treatment
#11
REVIEW
Wojciech Krajewski, Joanna Wojciechowska, Janusz Dembowski, Romuald Zdrojowy, Tomasz Szydełko
Ureteropelvic junction obstruction (UPJO) causes a reduction in the urine flow from the renal pelvis into the ureter. Untreated UPJO may cause hydronephrosis, chronic infection or urolithiasis and will often result in progressive deterioration of renal function. Most cases of UPJO are congenital; however, the disease can be clinically silent until adulthood. Other causes, both intrinsic and extrinsic, are acquired and include urolithiasis, post-operative/inflammatory/ischemic stricture, fibroepithelial polyps, adhesions and malignancy...
August 2017: Advances in Clinical and Experimental Medicine: Official Organ Wroclaw Medical University
https://www.readbyqxmd.com/read/29067207/abdominal-ultrasonography-of-the-healthy-howler-monkey-alouatta-fusca
#12
Raquel Sartor, Thiago R Müller, Maria J Mamprim, Carlos R Teixeira, Livia P de Souza, Ricardo C Lehmkuhl, Marilia G Luciani
Abdominal ultrasonography was performed in six healthy adult brown howler monkeys Alouatta fusca and the normal ultrasonographic anatomy of the liver, gallbladder, stomach and urinary tract described for the first time. Findings were compared with post-mortem studies. The renal cortex was isoechoic to the spleen and isoechoic or hyperechoic to the liver. Kidney length and renal arterial resistive index, systolic and diastolic velocity were calculated. The liver showed a homogeneous hypoechogenic echotexture...
February 2017: Veterinary Medicine and Science
https://www.readbyqxmd.com/read/29040332/the-developmental-programme-for-genesis-of-the-entire-kidney-is-recapitulated-in-wilms-tumour
#13
Ryuji Fukuzawa, Matthew R Anaka, Ian M Morison, Anthony E Reeve
Wilms tumour (WT) is an embryonal tumour that recapitulates kidney development. The normal kidney is formed from two distinct embryological origins: the metanephric mesenchyme (MM) and the ureteric bud (UB). It is generally accepted that WT arises from precursor cells in the MM; however whether UB-equivalent structures participate in tumorigenesis is uncertain. To address the question of the involvement of UB, we assessed 55 Wilms tumours for the molecular features of MM and UB using gene expression profiling, immunohistochemsitry and immunofluorescence...
2017: PloS One
https://www.readbyqxmd.com/read/29024453/the-histopathologic-reliability-of-tissue-taken-from-cadavers-within-the-gross-anatomy-laboratory
#14
Guenevere Rae, William P Newman, Robin McGoey, Supriya Donthamsetty, Aryn C Karpinski, Jeffrey Green
The purpose of this study was to examine the histopathologic reliability of embalmed cadaveric tissue taken from the gross anatomy laboratory. Tissue samples from hearts, livers, lungs, and kidneys were collected after the medical students' dissection course was completed. All of the cadavers were embalmed in a formalin-based fixative solution. The tissue was processed, embedded in paraffin, sectioned at six micrometers, and stained with H&E. The microscope slides were evaluated by a board certified pathologist to determine whether the cellular components of the tissues were preserved at a high enough quality to allow for histopathologic diagnosis...
October 10, 2017: Anatomical Sciences Education
https://www.readbyqxmd.com/read/29017666/protective-effects-of-nigella-sativaon-acetylsalicylic-acid-induced-nephrotoxicity-in-albino-rats
#15
Sania Asif, Lubna Malik
OBJECTIVE: To see the effects of Nigella sativaon acetylsalicylic acid-induced nephrotoxicity in albino rats. STUDY DESIGN: An experimental study. PLACE AND DURATION OF STUDY: The Anatomy Department of University of Health Sciences, Lahore, from January 2014 to December 2015. METHODOLOGY: Thirty-two female albino rats were divided into four groups. Group A(control) was given single dose of 10 mg/100 gm body weight of 1% methylcellulose, orally...
September 2017: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
https://www.readbyqxmd.com/read/28980056/does-the-type-of-renal-artery-anatomic-variant-determine-the-diameter-of-the-main-vessel-supplying-a-kidney-a-study-based-on-ct-data-with-a-particular-focus-on-the-presence-of-multiple-renal-arteries
#16
Marcin Majos, Ludomir Stefańczyk, Zofia Szemraj-Rogucka, Marcin Elgalal, Raffaele De Caro, Veronica Macchi, Michał Polguj
BACKGROUND: An in-depth knowledge of renal vascular anatomy is essential when planning many surgical procedures; however, a few data exists regarding renal artery diameter. The aim of this study was to assess this morphological feature and to investigate whether a correlation exists between renal artery diameter and the type of arterial supply, with a particular emphasis on variant anatomy and the presence of multiple renal arteries. MATERIALS AND METHODS: Computed tomography angiography (CTA) studies of 248 patients, i...
October 5, 2017: Surgical and Radiologic Anatomy: SRA
https://www.readbyqxmd.com/read/28968659/type-iii-cells-in-anterior-taste-fields-are-more-immunohistochemically-diverse-than-those-of-posterior-taste-fields-in-mice
#17
Courtney E Wilson, Thomas E Finger, Sue C Kinnamon
Activation of Type III cells in mammalian taste buds is implicated in the transduction of acids (sour) and salty stimuli. Several lines of evidence suggest that function of Type III cells in the anterior taste fields may differ from that of Type III cells in posterior taste fields. Underlying anatomy to support this observation is, however, scant. Most existing immunohistochemical data characterizing this cell type focus on circumvallate taste buds in the posterior tongue. Equivalent data from anterior taste fields-fungiform papillae and soft palate-are lacking...
October 31, 2017: Chemical Senses
https://www.readbyqxmd.com/read/28960296/comparative-anatomy-of-neonates-of-the-three-major-mammalian-groups-monotremes-marsupials-placentals-and-implications-for-the-ancestral-mammalian-neonate-morphotype
#18
Kirsten Ferner, Julia A Schultz, Ulrich Zeller
The existing different modes of reproduction in monotremes, marsupials and placentals are the main source for our current understanding of the origin and evolution of the mammalian reproduction. The reproductive strategies and, in particular, the maturity states of the neonates differ remarkably between the three groups. Monotremes, for example, are the only extant mammals that lay eggs and incubate them for the last third of their embryonic development. In contrast, marsupials and placentals are viviparous and rely on intra-uterine development of the neonates via choriovitelline (mainly marsupials) and chorioallantoic (mainly placentals) placentae...
September 28, 2017: Journal of Anatomy
https://www.readbyqxmd.com/read/28912007/adventitial-adipogenic-degeneration-is-an-unidentified-contributor-to-aortic-wall-weakening-in-the-abdominal-aortic-aneurysm
#19
Stefan A Doderer, Gabor Gäbel, Vivianne B C Kokje, Bernd H Northoff, Lesca M Holdt, Jaap F Hamming, Jan H N Lindeman
OBJECTIVE: The processes driving human abdominal aortic aneurysm (AAA) progression are not fully understood. Although antiinflammatory and proteolytic strategies effectively quench aneurysm progression in preclinical models, so far all clinical interventions failed. These observations hint at an incomplete understanding of the processes involved in AAA progression and rupture. Interestingly, strong clinical and molecular associations exist between popliteal artery aneurysms (PAAs) and AAAs; however, PAAs have an extremely low propensity to rupture...
September 11, 2017: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/28879095/unilateral-complete-agenesis-of-mesonephric-duct-derivatives-in-an-82-year-old-male-cadaver-embryology-anatomy-and-clinical-considerations
#20
David G Darcy, Morgen Yao-Cohen, Todd R Olson, Sherry A Downie
Development of urogenital anatomy in the human fetus is the result of a complex interplay between multiple different tissues. The time course of development is well documented and the morphologic outcomes of insults at various time points during development are predictable. We present a cadaveric case of unilateral agenesis of the left kidney, ureter, bladder hemitrigone, ureteric opening, seminal vesicle, vas deferens, and epididymis. Failure of development of the mesonephric duct early during embryogenesis, likely between the third and fifth week, caused ipsilateral urogenital organ agenesis...
November 2017: Urology Case Reports
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