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salivary glands ultrasound

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https://www.readbyqxmd.com/read/28530128/in-vivo-endocrine-secretion-of-prostacyclin-following-expression-of-a-cox-1-pgis-fusion-protein-in-the-salivary-glands-of-rats-via-non-viral-gene-therapy
#1
Zhimin Wang, Raymond L Benza, Lee Zourelias, Angela Sanguino, Ramaz Geguchadze, Kelly J Shields, Changgong Wu, Kristin B Highland, Michael J Passineau
Pulmonary arterial hypertension is a progressive disease that culminates in right heart failure and death. Prostacyclin(PGI2) and its derivatives are effective treatments for PAH when administered as continuous parenteral infusions. This treatment paradigm requires medical sophistication, and patients are at risk for complications from an indewelling catheter; drug interruptions may result in rebound pulmonary hypertension and death. We hypothesized that the salivary gland can be repurposed into an endogenous production site for circulating PGI2 through the expression of a fusion protein embodying cyclooxygenase-1(Cox1) and prostacyclin synthase(PGIS) domains...
May 20, 2017: Human Gene Therapy
https://www.readbyqxmd.com/read/28516976/salivary-duct-stenosis-diagnosis-and-treatment
#2
M Koch, H Iro
The management of stenoses of the major salivary glands had undergone a significant change during the last 15-20 years. Accurate diagnosis forms the basis of adapted minimal invasive therapy. Conventional sialography and MR-sialography are useful examination tools, and ultrasound seems to be a first-line investigational tool if salivary duct stenosis is suspected as cause of gland obstruction. Sialendoscopy is the best choice to establish final diagnosis and characterise the stenosis in order to plan accurate treatment...
April 2017: Acta Otorhinolaryngologica Italica
https://www.readbyqxmd.com/read/28516970/diagnostic-work-up-in-obstructive-and-inflammatory-salivary-gland-disorders
#3
L Ugga, M Ravanelli, A A Pallottino, D Farina, R Maroldi
Inflammatory and obstructive disorders of the salivary glands are caused by very different pathological conditions affecting the gland tissue and/or the excretory system. The clinical setting is essential to address the appropriate diagnostic imaging work-up. According to history and physical examination, four main clinical scenarios can be recognised: (1) acute generalised swelling of major salivary glands; (2) acute swelling of a single major salivary gland; (3) chronic generalised swelling of major salivary glands, associated or not with "dry mouth"; (4) chronic or prolonged swelling of a single major salivary gland...
April 2017: Acta Otorhinolaryngologica Italica
https://www.readbyqxmd.com/read/28493480/sonographic-findings-of-igg4-related-disease-of-the-salivary-glands-case-report-and-review-of-the-literature
#4
Anand K Narayan, Alan Baer, Joel Fradin
IgG4-related disease is a relatively newly described entity with findings that historically have been confused with a variety of other diseases with markedly different treatments and prognoses, including Sjogren's syndrome and MALT lymphoma. We present a case of IgG4-related disease of the salivary glands and review the literature on sonographic findings of IgG4-related disease. By connecting sonographic features of IgG4 disease with common ancillary features of IgG4 disease in other sites (pancreas, hilar lymph nodes, biliary tree, thyroid, and retroperitoneum), radiologists can play a pivotal role in the early diagnosis and identification of IgG4-related disease...
May 11, 2017: Journal of Clinical Ultrasound: JCU
https://www.readbyqxmd.com/read/28492904/screening-for-thyroid-cancer-updated-evidence-report-and-systematic-review-for-the-us-preventive-services-task-force
#5
Jennifer S Lin, Erin J Aiello Bowles, Selvi B Williams, Caitlin C Morrison
Importance: The incidence of detected thyroid cancer cases has been increasing in the United States since 1975. The majority of thyroid cancers are differentiated cancers with excellent prognosis and long-term survival. Objective: To systematically review the benefits and harms associated with thyroid cancer screening and treatment of early thyroid cancer in asymptomatic adults to inform the US Preventive Services Task Force. Data Sources: Searches of MEDLINE, PubMed, and the Cochrane Central Register of Controlled Trials for relevant studies published from January 1966 through January 2016, with active surveillance through December 2016...
May 9, 2017: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/28457107/congenital-absence-of-salivary-glands-in-fetuses-with-trisomy-21
#6
Marwan Odeh, Moshe Bronshtein, Jacob Bornstein
BACKGROUND: The congenital absence of salivary glands has been reported in children but never in fetuses with trisomy 21. OBJECTIVES: To determine whether the congenital absence of salivary glands can be detected prenatally between 13 and 16 weeks of gestation in normal and trisomy 21 fetuses using transvaginal ultrasound. METHODS: We performed a retrospective analysis of recordings of normal and trisomy 21 fetuses. Inclusion criteria were a single viable fetus and good visualization of the anatomic area of the salivary glands on both sides of the fetal face...
January 2017: Israel Medical Association Journal: IMAJ
https://www.readbyqxmd.com/read/28447158/-ultrasound-diagnostics-in-sj%C3%A3-gren-s-syndrome
#7
REVIEW
V S Schäfer, W A Schmidt
Ultrasound of the salivary glands is a specific examination for detecting pathology of salivary glands in the diagnosis of Sjögren's syndrome. It is easy to learn, rapidly performed, non-invasive and inexpensive. Other imaging techniques, such as sialography and scintigraphy, are currently only rarely performed. For the examination, linear ultrasound probes with frequencies between 7 and 12 MHz are recommended. Such probes are already widely available to the rheumatologist performing musculoskeletal ultrasound...
April 26, 2017: Zeitschrift Für Rheumatologie
https://www.readbyqxmd.com/read/28348790/streptococcus-pneumoniae-bacteraemia-due-to-parotitis-in-a-patient-with-systemic-sclerosis-and-secondary-sj%C3%A3-gren-s-syndrome
#8
Irene Yuen Lin Yii, Jamie Bee Xian Tan, Warren Weng Seng Fong
INTRODUCTION: Invasive pneumococcal disease is an uncommon and notifiable disease in Singapore. It is often associated with significant morbidity and mortality. We report a rare case of invasive pneumococcal bacteraemia due to parotitis in a patient with systemic sclerosis and secondary Sjögren's syndrome. We also present a retrospective review of Streptococcus pneumoniae bacteraemia cases in Singapore General Hospital from January 2011 to April 2016. CASE PRESENTATION: A 59-year-old Malay lady with a history of systemic sclerosis with secondary Sjögren's syndrome presented with fever and left parotid gland swelling...
October 2016: JMM Case Reports
https://www.readbyqxmd.com/read/28330576/-interests-of-the-ultrasound-guidance-in-the-treatment-of-drooling-through-botulinum-toxin-injections-our-experience-over-10%C3%A2-years
#9
M Mailly, C Rebours, P Koskas, P Klap, D Ayache, M Cohen
OBJECTIVES: To report about our 10 years' experience about the treatment of drooling by ultrasound guided botulinum toxin injections. MATERIAL AND METHODS: Retrospective monocentric study including all the patients suffering from drooling and treated by ultrasound-guided botulinum toxin injections into the salivary glands between 2004 and 2015. The etiology of r drooling, the doses of toxin, the injected glands, the size of the glands measured by ultrasonography, the effectiveness of the treatment and the side effects were assessed...
February 2017: Journal of Stomatology, Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28289635/accuracy-of-ultrasound-guided-and-non-ultrasound-guided-botulinum-toxin-injection-into-cadaver-salivary-glands
#10
Jae In So, Dae Heon Song, Joo Hyun Park, Eunseok Choi, Jung Yoon Yoon, Yeonji Yoo, Myung Eun Chung
OBJECTIVE: To compare the accuracy of ultrasound (US)-guided and non-US-guided botulinum toxin (BTX) injection into the salivary glands (parotid and submandibular glands) of cadavers. METHODS: Two rehabilitation physician injected dye into three sites in the salivary glands (two sites in the parotid gland and one site in the submandibular gland) on one side of each cadaver (one was injected on the right side, while the other was injected on the left side), using either a non-US-guided injection procedure based on superficial landmarks or a US-guided procedure...
February 2017: Annals of Rehabilitation Medicine
https://www.readbyqxmd.com/read/28277296/botox-a-injection-of-salivary-glands-for-drooling
#11
Ana Alvarenga, Miguel Campos, Mariana Dias, Lina Melão, José Estevão-Costa
BACKGROUND AND PURPOSE: Drooling is a challenging entity to manage. Botulinum toxin A (BOTOX-A) infiltration of salivary glands is a promising alternative to surgical treatment. This study aims to assess the outcome of BOTOX-A salivary glands infiltration in children with drooling. METHODS: Patients treated between January 2012 and March 2015 were enrolled. BOTOX-A was injected in the parotid and submandibular glands under ultrasound control and general inhalational anesthesia...
October 14, 2016: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/28270226/first-in-man-mesenchymal-stem-cells-for-radiation-induced-xerostomia-mesrix-study-protocol-for-a-randomized-controlled-trial
#12
Christian Grønhøj, David H Jensen, Peter V Glovinski, Siri Beier Jensen, Allan Bardow, Roberto S Oliveri, Lena Specht, Carsten Thomsen, Sune Darkner, Katalin Kiss, Anne Fischer-Nielsen, Christian von Buchwald
BACKGROUND: Salivary gland hypofunction and xerostomia are major complications following radiotherapy for head and neck cancer and may lead to debilitating oral disorders and impaired quality of life. Currently, only symptomatic treatment is available. However, mesenchymal stem cell (MSC) therapy has shown promising results in preclinical studies. Objectives are to assess safety and efficacy in a first-in-man trial on adipose-derived MSC therapy (ASC) for radiation-induced xerostomia...
March 7, 2017: Trials
https://www.readbyqxmd.com/read/28249724/time-course-of-ultrasound-abnormalities-of-major-salivary-glands-in-suspected-sj%C3%A3-gren-s-syndrome
#13
Pierre Gazeau, Divi Cornec, Sandrine Jousse-Joulin, Dewi Guellec, Alain Saraux, Valérie Devauchelle-Pensec
OBJECTIVE: To evaluate whether major salivary-gland ultrasonography (SGUS) abnormalities change over time in patients with suspected primary Sjögren's syndrome (pSS) during the natural course of the disease. METHODS: We studied patients with suspected pSS who were included in the Brittany cohort of suspected pSS and underwent SGUS at least twice, as part of the routine diagnostic workup done at baseline then at least 1 year later as an additional investigation deemed appropriate by the physician...
February 27, 2017: Joint, Bone, Spine: Revue du Rhumatisme
https://www.readbyqxmd.com/read/28191301/plunging-ranula-in-children-case-report-and-literature-review
#14
Veronica Carlini, Valeria Calcaterra, Noemi Pasqua, Marinella Guazzotti, Mario Fusillo, Gloria Pelizzo
Few cases of plunging ranulas (PRs) occur during childhood and the lesions are frequently misdiagnosed. Here, a PR in a child is reported along with a literature review. A seven-year-old female complaining of swelling in the midline neck, left-submandibular region, was evaluated. No oral cavity or major salivary glands abnormalities were detected. On palpation, a soft, painless, and fluid-containing mass was observed. The suspicion PR was performed by ultrasound. The diagnosis was confirmed with a histopathological examination...
November 17, 2016: Pediatric Reports
https://www.readbyqxmd.com/read/28180194/prospective-evaluation-of-quasistatic-ultrasound-elastography-use-compared-with-baseline-us-for-parotid-gland-lesions-preliminary-results-of-elasticity-contrast-index-eci-evaluation
#15
Vito Cantisani, Emanuele David, Armando De Virgilio, Paul S Sidhu, Hektor Grazhdani, Antonio Greco, Marco De Vincentiis, Alessandro Corsi, Flaminia De Cristofaro, Luca Brunese, Fabrizio Calliada, Alfredo Blandino, Mario Tombolini, Giorgio Ascenti, Roberto Stramare, Marcello Caratozzolo, Ferdinando D'Ambrosio
AIMS: To assess the diagnostic value of elasticity contrast index (ECI) elastography, in comparison with conventional ultrasound for the differentiation of benign and malignant parotid lesions. MATERIAL AND METHODS: Sixty-three consecutive patients with parotid gland tumors, treated surgically at a single tertiary center were enrolled. Ultrasound evaluation consisted of B-mode, color-Doppler and quasistatic ultrasound elastography (USE), conducted with the ECI technique...
January 31, 2017: Medical Ultrasonography
https://www.readbyqxmd.com/read/28103850/acupuncture-for-primary-sj%C3%A3-gren-syndrome-pss-on-symptomatic-improvements-study-protocol-for-a-randomized-controlled-trial
#16
RANDOMIZED CONTROLLED TRIAL
Quan Jiang, Huadong Zhang, Ran Pang, Jinzhou Chen, Zhishun Liu, Xinyao Zhou
BACKGROUND: Currently, feasible medical treatments are hitherto not satisfying to relieve pSS symptoms, which concerns numbers of clinical doctors. Acupuncture seems to be an alternative to treat pSS and conduces to good symptomatic results. However further research is necessary. This trial is to investigate the efficacy of acupuncture on improving the key symptoms of pSS, which are dryness, pain and fatigue (DPF). METHODS & DESIGN: The study is designed as a randomized controlled trial of two arms with a single centre...
January 19, 2017: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/27986264/imaging-of-palatal-lumps
#17
REVIEW
C von Stempel, S Morley, T Beale, S Otero
Palatal tumours are relatively rare and of variable aetiology, rendering radiological evaluation a daunting process for many. A systematic approach to the imaging of a palatal lump is therefore essential. The hard and soft palates are oral cavity and oropharyngeal structures, respectively. They have different tissue compositions, and therefore, lesions occur with different frequencies at each site. The hard palate has the highest concentration of minor salivary glands in the upper aerodigestive tract and most tumours here are salivary in origin, whereas most tumours at the soft palate are epithelial in origin, i...
February 2017: Clinical Radiology
https://www.readbyqxmd.com/read/27942480/diagnostic-imaging-of-benign-and-malignant-neck-masses-in-children-a-pictorial-review
#18
REVIEW
Ruth Elizabeth Brown, Srikrishna Harave
Neck masses are frequently encountered in pediatric medicine, and can present a diagnostic dilemma for the clinicians involved. There are several means by which neck masses in children can be subdivided, for example by age at presentation, anatomical location including compartments and fascia of the neck, their classical appearance when imaged, or by etiology. When imaging children the clinicians must be mindful of radiation exposure and as such ultrasound (US) is often attempted first. Cross sectional imaging can be helpful for problem solving with CT being particularly useful for assessing the patient in more acute scenarios, for example when there is airway compromise...
October 2016: Quantitative Imaging in Medicine and Surgery
https://www.readbyqxmd.com/read/27941210/-contemporary-diagnostics-of-the-primary-sj%C3%A3-gren-s-syndrome
#19
Jolanta Parada-Turska
Primary Sjögren's syndrome is one of the most common systemic autoimmune disorders, whose diagnosis is very often delayed. In most cases it is a mild disease with symptoms such as dryness and musculoskeletal pain and fatigue but 20-40% of patients suffer from severe systemic manifestations. Extraglandular manifestations can be the first sign of the disease, therefore it is very important to diagnose them as early as possible. Classification criteria established by the American-European Consensus Group (AECG) have been applied in primary Sjögren's syndrome diagnosis since 2002...
2016: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/27931961/imaging-of-connective-tissue-diseases-beyond-visceral-organ-imaging
#20
REVIEW
Maurizio Cutolo, Nemanja Damjanov, Barbara Ruaro, Ana Zekovic, Vanessa Smith
Connective tissues diseases (CTDs) can also be diagnosed early by "external" and safe imaging methods beyond the visceral organ analysis. This study aims to explore various imaging techniques used in diagnosing CTDs. Skin impairment in systemic sclerosis (SSc) may be recognized and studied by the modified Rodnan skin score (mRSS), which has some drawbacks, whereas high-frequency ultrasound (US) seems advantageous for the early identification of skin involvement. Salivary gland involvement in Sjögren syndrome (SS) can be assessed using standard tests such as unstimulated salivary flow test, salivary gland scintigraphy or contrast sialography...
August 2016: Best Practice & Research. Clinical Rheumatology
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