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https://www.readbyqxmd.com/read/28240173/personalized-medicine-of-alcohol-addiction-pharmacogenomics-and-beyond
#1
Vangelis George Manolopoulos, Georgia Ragia
Alcohol addiction or alcoholism is the most severe form of problem drinking. A variety of treatment methods for alcoholism are currently available that combine medications, behavioral treatment and peer support. The drugs that are currently approved by the U.S. Food and Drug Administration (FDA) for treatment of alcohol dependence are disulfiram, naltrexone and acamprosate. For many patients, however, these treatments are not effective. Evidence from a number of different studies suggests that different factors, both psychosocial and economic, as well as genetic variation, are significant contributors to interindividual variation both of clinical presentation of alcohol problems and response to a given treatment...
February 23, 2017: Current Pharmaceutical Biotechnology
https://www.readbyqxmd.com/read/28239075/time-dependent-changes-in-psychosocial-distress-in-japanese-patients-with-implantable-cardioverter-defibrillators
#2
Nao Saito, Chiemi Taru, Ikuko Miyawaki
This prospective study clarified changes in the mood states of Japanese patients with implantable cardioverter defibrillators as well as factors related to the mood states. Using a longitudinal repeated-measure design, 29 patients with implantable cardioverter defibrillators completed the Profile of Mood States-Short Form Japanese Version questionnaire before discharge and 1, 4, 7, and 13 months after implantation. One month after discharge, the mood states of the patients with implantable cardioverter defibrillators improved...
December 2, 2016: Kobe Journal of Medical Sciences
https://www.readbyqxmd.com/read/28238090/general-health-status-in-army-personnel-relations-with-health-behaviors-and-psychosocial-variables
#3
Samuel Golenbock, Josh B Kazman, Stephen Krauss, Patricia A Deuster
PURPOSE: Poor self-rated health (SRH) is linked to an increased risk of injury, future healthcare services utilization, and morbidity and mortality. This study aimed to identify correlates of a single-item measure of health in 8070 US Army personnel. METHODS: Responses were collected from the Army's global assessment tool (GAT) 2.0, an online questionnaire that assesses physical and psychosocial health. SRH was measured by the item, "How do you consider your health?" (four response categories: "poor," "fair," "good," and "excellent")...
February 25, 2017: Quality of Life Research
https://www.readbyqxmd.com/read/28237955/advance-care-planning-uptake-among-patients-with-severe-lung-disease-a-randomised-patient-preference-trial-of-a-nurse-led-facilitated-advance-care-planning-intervention
#4
Craig Sinclair, Kirsten Anne Auret, Sharon Frances Evans, Fiona Williamson, Siobhan Dormer, Anne Wilkinson, Kim Greeve, Audrey Koay, Dot Price, Fraser Brims
OBJECTIVE: Advance care planning (ACP) clarifies goals for future care if a patient becomes unable to communicate their own preferences. However, ACP uptake is low, with discussions often occurring late. This study assessed whether a systematic nurse-led ACP intervention increases ACP in patients with advanced respiratory disease. DESIGN: A multicentre open-label randomised controlled trial with preference arm. SETTING: Metropolitan teaching hospital and a rural healthcare network...
February 24, 2017: BMJ Open
https://www.readbyqxmd.com/read/28236729/parental-stress-pediatric-quality-of-life-and-behavior-at-baseline-and-one-year-follow-up-results-from-the-febstat-study
#5
Ruth C Shinnar, Shlomo Shinnar, Dale C Hesdorffer, Kathryn O'Hara, Terrie Conklin, Karen Mohler Cornett, Diana Miazga, Shumei Sun
: Febrile status epilepticus is a serious and frightening event in the life of the child and parent. It is regarded as a medical emergency with potential long lasting consequences. The purpose of this study was to look at the immediate and long term effects of such an event on parental stress and parents' perception of their child's physical and psychosocial wellbeing. METHODS: From 2003 to 2010, 199 subjects, age 1 month to 5 years, were recruited as part of a prospective, multicenter study (FEBSTAT) of consequences of febrile status epilepticus (FSE)...
February 22, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28235963/fatigue-and-its-associated-factors-in-liver-transplant-recipients-in-beijing-a-cross-sectional-study
#6
Xiao-Hong Lin, Sha Teng, Lu Wang, Jing Zhang, Ya-Bin Shang, Hong-Xia Liu, Yun-Jin Zang
OBJECTIVES: Fatigue is a highly prevalent symptom experienced by patients who underwent the liver transplantation. However, the influencing factors of fatigue are poorly understood by healthcare professionals. The aim of this study was to examine the intensity, interference, duration and prevalence of fatigue in liver transplantation recipients and to explore the influencing factors of post-transplantation fatigue. DESIGN: A cross-sectional design was used in this study...
February 23, 2017: BMJ Open
https://www.readbyqxmd.com/read/28235542/identifying-demographic-and-psychosocial-factors-related-to-the-escalation-of-smoking-behavior-among-mexican-american-adolescents
#7
Sahil S Shete, Anna V Wilkinson
Cigarette smoking is the leading preventable cause of death in the United States; smoking in Mexican American adolescents, a rapidly growing population, remains a major concern. Factors associated with escalation or progression along the smoking trajectory have not been studied in adolescent Mexican Americans. A better understanding of escalation is needed for cancer prevention and overall health. N=1,328 Mexican American adolescents joined a cohort in 2005-06. At baseline participants provided demographic, acculturation and psychosocial data, and reported their smoking status using the Minnesota Smoking Index...
February 21, 2017: Preventive Medicine
https://www.readbyqxmd.com/read/28231685/unmet-psychosocial-needs-in-adolescents-with-inflammatory-bowel-disease
#8
(no author information available yet)
BACKGROUND: Inflammatory bowel diseases (IBD) are severe medical conditions with adverse impact on the quality of life of both children and their caregivers. IBD are associated with many limitations in personal and interpersonal functioning, and it also restricts the patients' ability to use the full potential (extent) of their capabilities. With the progress and humanization in society, the issue of patients' needs became an important topic; however, the psychosocial functioning and quality of life of adolescents suffering from IBD and their caregivers have been understudied...
October 24, 2016: Neuro Endocrinology Letters
https://www.readbyqxmd.com/read/28229345/predictors-and-prevalence-of-recovery-and-remission-for-consumers-discharged-from-mental-hospitals-in-a-chinese-society
#9
Daniel K W Young, Petrus Y N Ng, Jiayan Pan
This research study examines the 1 year rate of recovery and remissions for consumers recently discharging from mental hospitals and identifies factors predicting recovery and remissions in the Hong Kong context. By adopting a prospective longitudinal follow-up research design, a cohort of Chinese people discharged from the mental hospitals and participating in a community-based psychosocial program was followed for 1 year. These individuals were assessed by using standardized assessment scales at baseline, 6 months, and 12 months of follow-up...
February 23, 2017: Psychiatric Quarterly
https://www.readbyqxmd.com/read/28229112/chronic-psychosocial-stressors-in-adulthood-studies-in-mice-rats-and-tree-shrews
#10
REVIEW
Christopher R Pryce, Eberhard Fuchs
Human psychological stress is the major environmental risk factor for major depression and certain of the anxiety disorders. Psychological stressors often occur in the context of the adult social environment, and they or the memory formed of them impact on the individual across an extended period, thereby constituting chronic psychosocial stress (CPS). Psychosocial stressors often involve loss to the individual, such as the ending of a social relationship or the onset of interpersonal conflict leading to loss of social control and predictability...
February 2017: Neurobiology of Stress
https://www.readbyqxmd.com/read/28228453/impaired-health-status-psychological-distress-and-personality-in-women-and-men-with-nonobstructive-coronary-artery-disease-sex-and-gender-differences-the-twist-tweesteden-mild-stenosis-study
#11
Paula M C Mommersteeg, Lindy Arts, Wobbe Zijlstra, Jos W Widdershoven, Wilbert Aarnoudse, Johan Denollet
BACKGROUND: Patients with nonobstructive coronary artery disease (NOCAD; wall irregularities, stenosis <60%), and women with NOCAD in particular, remain underinvestigated. We examined sex and gender (S&G) differences in health status, psychological distress, and personality between patients with NOCAD and the general population, as well as S&G differences within the NOCAD population. METHODS AND RESULTS: In total, 523 patients with NOCAD (61±9 years, 52% women) were included via coronary angiography and computed tomography as part of the TWIST (Tweesteden Mild Stenosis) study...
February 2017: Circulation. Cardiovascular Quality and Outcomes
https://www.readbyqxmd.com/read/28225508/suicidal-ideation-vs-suicide-attempts-clinical-and-psychosocial-profile-differences-among-depressed-patients-a-study-on-personality-traits-psychopathological-variables-and-sociodemographic-factors-in-228-patients
#12
Ute Lewitzka, Sina Spirling, Dirk Ritter, Michael Smolka, Sarah Goodday, Michael Bauer, Werner Felber, Tom Bschor
This study investigated whether personality traits, psychopathological characteristics, and sociodemographic factors in depressed patients differentiate patients with only suicidal thoughts from those who have attempted suicide. We investigated two groups of patients with an affective disorder: 198 patients with a suicide attempt within the last 3 months (sex ratio male to female, 1:1.3; mean age male to female, 44.8/44.7 years) and 30 patients without a suicide attempt but with suicidal thoughts (sex ratio male to female, 1:2; mean age male to female, 39...
February 20, 2017: Journal of Nervous and Mental Disease
https://www.readbyqxmd.com/read/28224953/perceived-learning-needs-of-patients-with-abdominal-aortic-aneurysm
#13
Olga Nilsson, Rebecka Hultgren, Anna Letterstål
BACKGROUND: Patients undergoing surgical treatment of abdominal aortic aneurysm (AAA) should receive adequate information about the disease, treatment options, and self-care. Patients' learning needs should be acknowledged. The aim was to describe the perceived learning needs in patients with AAA. A secondary aim was to explore their experience of methods for patient education. METHODS: Three focus group interviews were conducted with 14 patients treated with open or endovascular repair of AAA...
March 2017: Journal of Vascular Nursing: Official Publication of the Society for Peripheral Vascular Nursing
https://www.readbyqxmd.com/read/28224414/does-the-length-of-disability-between-injury-and-functional-restoration-program-entry-affect-treatment-outcomes-for-patients-with-chronic-disabling-occupational-musculoskeletal-disorders
#14
Sali Asih, Randy Neblett, Tom G Mayer, Robert J Gatchel
Purpose Functional restoration programs (FRPs), for patients with chronic disabling occupational musculoskeletal disorders (CDOMDs), have consistently demonstrated positive socioeconomic treatment outcomes, including decreased psychosocial distress and increased work return. The pre-treatment length of disability (LOD), or time between injury and treatment admission, has been shown to influence FRP work outcomes. Some studies have found that shorter LOD is associated with better work outcomes. However, few studies have actually examined cohorts with LOD duration longer than 18 months...
February 21, 2017: Journal of Occupational Rehabilitation
https://www.readbyqxmd.com/read/28224404/video-gaming-and-children-s-psychosocial-wellbeing-a-longitudinal-study
#15
Adam Lobel, Rutger C M E Engels, Lisanne L Stone, William J Burk, Isabela Granic
The effects of video games on children's psychosocial development remain the focus of debate. At two timepoints, 1 year apart, 194 children (7.27-11.43 years old; male = 98) reported their gaming frequency, and their tendencies to play violent video games, and to game (a) cooperatively and (b) competitively; likewise, parents reported their children's psychosocial health. Gaming at time one was associated with increases in emotion problems. Violent gaming was not associated with psychosocial changes. Cooperative gaming was not associated with changes in prosocial behavior...
February 21, 2017: Journal of Youth and Adolescence
https://www.readbyqxmd.com/read/28224276/preparedness-and-cancer-related-symptom-management-among-cancer-survivors-in-the-first-year-post-treatment
#16
Corinne R Leach, Alyssa N Troeschel, Dawn Wiatrek, Annette L Stanton, Michael Diefenbach, Kevin D Stein, Katherine Sharpe, Kenneth Portier
BACKGROUND: Many cancer survivors feel unprepared for the physical and psychosocial challenges that accompany the post-treatment care transition (i.e., re-entry phase), including management of cancer-related symptoms. Few studies have investigated personal and contextual factors associated with the extent of preparedness for re-entry or how they are related to cancer-related symptom management. PURPOSE: Data from the American Cancer Society's Cancer Survivor Transition Study examined (1) characteristics of breast, prostate, and colorectal cancer survivors (n = 1188) within the first year of completing treatment who are most and least prepared for re-entry; and (2) how preparedness level and other characteristics are related to cancer-related symptom management...
February 21, 2017: Annals of Behavioral Medicine: a Publication of the Society of Behavioral Medicine
https://www.readbyqxmd.com/read/28223731/risk-of-alcohol-use-relapse-after-liver-transplantation-for-alcoholic-liver-disease
#17
Yasuharu Onishi, Hiroyuki Kimura, Tomohide Hori, Shinichi Kishi, Hideya Kamei, Nobuhiko Kurata, Chisato Tsuboi, Naoko Yamaguchi, Mayu Takahashi, Saki Sunada, Mitsuaki Hirano, Hiroshige Fujishiro, Takashi Okada, Masatoshi Ishigami, Hidemi Goto, Norio Ozaki, Yasuhiro Ogura
AIM: To investigate factors, including psychosocial factors, associated with alcoholic use relapse after liver transplantation (LT) for alcoholic liver disease (ALD). METHODS: The clinical records of 102 patients with ALD who were referred to Nagoya University Hospital for LT between May 2003 and March 2015 were retrospectively evaluated. History of alcohol intake was obtained from their clinical records and scored according to the High-Risk Alcoholism Relapse scale, which includes duration of heavy drinking, types and amount of alcohol usually consumed, and previous inpatient treatment history for alcoholism...
February 7, 2017: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/28223082/negative-emotions-and-suicidal-ideation-during-psychosocial-treatments-in-older-adults-with-major-depression-and-cognitive-impairment
#18
Dimitris N Kiosses, James J Gross, Samprit Banerjee, Paul R Duberstein, David Putrino, George S Alexopoulos
OBJECTIVE: To examine the relationship of negative emotions with suicidal ideation during 12 weeks of Problem Adaptation Therapy (PATH) versus Supportive Therapy of Cognitively Impaired Older Adults (ST-CI), hypothesizing that improved negative emotions are associated with reduced suicidal ideation, PATH improves negative emotions more than ST-CI, and improved negative emotions, rather than other depression symptoms, predict reduction in suicidal ideation. METHODS: In a randomized controlled trial of two home-delivered psychosocial interventions, 74 older participants (65-95 years old) with major depressive disorder and cognitive impairment were recruited in collaboration with community agencies...
January 19, 2017: American Journal of Geriatric Psychiatry
https://www.readbyqxmd.com/read/28222818/store-directed-price-promotions-and-communications-strategies-improve-healthier-food-supply-and-demand-impact-results-from-a-randomized-controlled-baltimore-city-store-intervention-trial
#19
Nadine Budd, Jayne K Jeffries, Jessica Jones-Smith, Anna Kharmats, Ann Yelmokas McDermott, Joel Gittelsohn
OBJECTIVE: Small food store interventions show promise to increase healthy food access in under-resourced areas. However, none have tested the impact of price discounts on healthy food supply and demand. We tested the impact of store-directed price discounts and communications strategies, separately and combined, on the stocking, sales and prices of healthier foods and on storeowner psychosocial factors. DESIGN: Factorial design randomized controlled trial. SETTING: Twenty-four corner stores in low-income neighbourhoods of Baltimore City, MD, USA...
February 22, 2017: Public Health Nutrition
https://www.readbyqxmd.com/read/28222781/the-complex-interplay-between-clinical-and-person-centered-diabetes-outcomes-in-the-two-genders
#20
Maria Chiara Rossi, Giuseppe Lucisano, Basilio Pintaudi, Angela Bulotta, Sandro Gentile, Marco Scardapane, Soren Eik Skovlund, Giacomo Vespasiani, Antonio Nicolucci
BACKGROUND: New approaches to cope with clinical and psychosocial aspects of type 2 diabetes (T2DM) are needed; gender influences the complex interplay between clinical and non-clinical factors. We used data from the BENCH-D study to assess gender-differences in terms of clinical and person-centered measures in T2DM. METHODS: Clinical quality of care indicators relative to control of HbA1c, lipid profile, blood pressure, and BMI were derived from electronic medical records...
February 21, 2017: Health and Quality of Life Outcomes
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