keyword
MENU ▼
Read by QxMD icon Read
search

EVD

keyword
https://www.readbyqxmd.com/read/28520958/the-development-use-and-impact-of-a-global-laboratory-database-during-the-2014-ebola-outbreak-in-west-africa
#1
Kara N Durski, Shalini Singaravelu, Junxiong Teo, Dhamari Naidoo, Luke Bawo, Amara Jambai, Sakoba Keita, Ali Ahmed Yahaya, Beatrice Muraguri, Brice Ahounou, Victoria Katawera, Fredson Kuti-George, Yacouba Nebie, T Henry Kohar, Patrick Jowlehpah Hardy, Mamoudou Harouna Djingarey, David Kargbo, Nuha Mahmoud, Yewondwossen Assefa, Orla Condell, Magassouba N'Faly, Leon Van Gurp, Margaret Lamanu, Julia Ryan, Boubacar Diallo, Foday Daffae, Dikena Jackson, Fayyaz Ahmed Malik, Philomena Raftery, Pierre Formenty
Background: The international impact, rapid widespread transmission, and reporting delays during the 2014 Ebola virus disease (EVD) outbreak in West Africa highlighted the need for a global, centralized database to inform outbreak response. The World Health Organization and Emerging and Dangerous Pathogens Laboratory Network addressed this need by supporting the development of a global laboratory database. Methods: Specimens were collected in the affected countries from patients and dead bodies meeting the case definitions for EVD...
May 18, 2017: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28520805/identification-of-key-contributors-in-complex-population-structures
#2
Markus Neuditschko, Herman W Raadsma, Mehar S Khatkar, Elisabeth Jonas, Eike J Steinig, Christine Flury, Heidi Signer-Hasler, Mirjam Frischknecht, Ruedi von Niederhäusern, Tosso Leeb, Stefan Rieder
Evaluating the genetic contribution of individuals to population structure is essential to select informative individuals for genome sequencing, genotype imputation and to ascertain complex population structures. Existing methods for the selection of informative individuals for genomic imputation solely focus on the identification of key ancestors, which can lead to a loss of phasing accuracy of the reference population. Currently many methods are independently applied to investigate complex population structures...
2017: PloS One
https://www.readbyqxmd.com/read/28506274/contextual-and-psychosocial-factors-predicting-ebola-prevention-behaviours-using-the-ranas-approach-to-behaviour-change-in-guinea-bissau
#3
Anna E Gamma, Jurgita Slekiene, Gregor von Medeazza, Fredrik Asplund, Placido Cardoso, Hans-Joachim Mosler
BACKGROUND: The outbreak of the Ebola virus disease (EVD) in West Africa in December 2013 was the largest Ebola outbreak in history. This study aimed to measure the underlying contextual and psychosocial factors of intentions to perform Ebola prevention behaviours (not touching people who might be suffering from Ebola, reporting suspected cases to the National Ebola Hotline, NEH) in Guinea-Bissau. Geographical location, cross-border market activities, poor water, sanitation and hygiene (WASH) conditions, and burial practices in some communities pose a serious risk in terms of potential EVD outbreak and seriously hamper its prevention in Guinea-Bissau...
May 15, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28505171/rapid-deployment-of-a-mobile-biosafety-level-3-laboratory-in-sierra-leone-during-the-2014-ebola-virus-epidemic
#4
Yi Zhang, Yan Gong, Chengyu Wang, Wensen Liu, Zhongyi Wang, Zhiping Xia, Zhaoyang Bu, Huijun Lu, Yang Sun, Xiaoguang Zhang, Yuxi Cao, Fan Yang, Haoxiang Su, Yi Hu, Yongqiang Deng, Bo Zhou, Zongzheng Zhao, Yingying Fu, David Kargbo, Foday Dafae, Brima Kargbo, Alex Kanu, Linna Liu, Jun Qian, Zhendong Guo
BACKGROUND: Ebola virus emerged in West Africa in December 2013. The high population mobility and poor public health infrastructure in this region led to the development of the largest Ebola virus disease (EVD) outbreak to date. METHODOLOGY/PRINCIPAL FINDINGS: On September 26, 2014, China dispatched a Mobile Biosafety Level-3 Laboratory (MBSL-3 Lab) and a well-trained diagnostic team to Sierra Leone to assist in EVD diagnosis using quantitative real-time PCR, which allowed the diagnosis of suspected EVD cases in less than 4 hours from the time of sample receiving...
May 15, 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28493945/ebola-virus-rna-detection-on-fomites-in-close-proximity-to-confirmed-ebola-patients-n-zerekore-guinea-2015
#5
Romain Palich, Leonid M Irenge, Eric Barte de Sainte Fare, Augustin Augier, Denis Malvy, Jean-Luc Gala
OBJECTIVE: Health care workers (HCWs) in contact with patients with Ebola virus disease (EVD) are exposed to a risk of viral contamination. Fomites contaminated with the patient's blood or body fluids represents this risk. Our study aims to detect Ebola virus (EBOV) RNA within the high- and low-risk areas of an Ebola treatment unit (ETU) located in inland Guinea during the 2014-2015 West African Ebola epidemics. For samples from patients' immediate vicinity, we aim to seek an association between viral RNA detectability and level of plasma viral load of patients (intermediate to high, or very high)...
2017: PloS One
https://www.readbyqxmd.com/read/28484529/secondary-communicating-hydrocephalus-management-by-implantation-of-external-ventricular-shunt-and-minimal-gradual-increase-of-cerebrospinal-fluid-pressure
#6
Keyvan Mostofi, Madjid Samii
BACKGROUND: This paper presents a new management strategy explaining the process used by implantation of external ventricular drainage (EVD) and very gradual increase of intracranial pressure for treatment of acute hydrocephalus. During the last 30 years' experience in professional practice, the senior author (M.S.) discovered that there are some options of regulations between cerebral spinal fluid (CSF) production and resorption. This theory shows that minimal continuous increase of the CSF pressure as long as the patient general neurological condition is unchanged and appears as normal can lead to definitive treatment of hydrocephalus without needing to set a shunt...
April 2017: Asian Journal of Neurosurgery
https://www.readbyqxmd.com/read/28479523/lesion-optimization-for-laser-ablation-fluid-evacuation-prior-to-laser-induced-thermal-therapy
#7
Timothy Wong, Nitesh V Patel, Filipe Feiteiro, Shabbar F Danish, Simon Hanft
BACKGROUND: Magnetic Resonance Guided Laser-Induced Thermal Therapy (MRgLITT) is a minimally invasive surgical procedure for ablating intracranial lesions. However, the presence of a fluid body can sequester thermal energy generated by the laser catheter.1-5 This compromises the performance of MRgLITT, and results in suboptimal ablation of cystic lesions. The authors report their surgical approach, namely stereotactic fluid aspiration followed by MRgLITT, on two patients with cystic brain tumors...
May 4, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28461209/insights-from-clinical-research-completed-during-the-west-africa-ebola-virus-disease-epidemic
#8
REVIEW
Amanda Rojek, Peter Horby, Jake Dunning
The west Africa Ebola virus disease (EVD) epidemic was extraordinary in scale. Now that the epidemic has ended, it is a relevant time to examine published studies with direct relevance to clinical care and, more broadly, to examine the implications of the clinical research response mounted. Clinically relevant research includes literature detailing risk factors for and clinical manifestations of EVD, laboratory and other investigation findings in patients, experimental vaccine and therapeutic clinical trials, and analyses of survivor syndrome...
April 28, 2017: Lancet Infectious Diseases
https://www.readbyqxmd.com/read/28459838/ebola-management-centre-proximity-associated-with-reduced-delays-of-healthcare-of-ebola-virus-disease-evd-patients-tonkolili-sierra-leone-2014-15
#9
Georgios Theocharopoulos, Kostas Danis, Jane Greig, Alexandra Hoffmann, Henriette De Valk, Augustine Jimissa, Sumaila Tejan, Mohammed Sankoh, Karline Kleijer, Will Turner, Jay Achar, Jennifer Duncombe, Kamalini Lokuge, Ivan Gayton, Rob Broeder, Ronald Kremer, Grazia Caleo
Between August-December 2014, Ebola Virus Disease (EVD) patients from Tonkolili District were referred for care to two Médecins Sans Frontières (MSF) Ebola Management Centres (EMCs) outside the district (distant EMCs). In December 2014, MSF opened an EMC in Tonkolili District (district EMC). We examined the effect of opening a district-based EMC on time to admission and number of suspect cases dead on arrival (DOA), and identified factors associated with fatality in EVD patients, residents in Tonkolili District...
2017: PloS One
https://www.readbyqxmd.com/read/28457350/ebola-virus-disease-an-update-on-epidemiology-symptoms-laboratory-findings-diagnostic-issues-and-infection-prevention-and-control-issues-for-laboratory-professionals
#10
REVIEW
Colin S Brown, Stephen Mepham, Robert J Shorten
The 2014 to 2016 Ebola virus disease (EVD), through the sheer size of the outbreak and combined experience within both resource-rich and resource-poor settings, allowed for more information to be gained about the clinical and pathologic features of EVD. This review highlights the range of aspects of EVD that the authors find are relevant to laboratory medicine, including the need for robust prediagnostic and laboratory processing algorithms to inform sampling of suspect patients, the vast majority of whom, in resource-rich settings, will have another diagnosis...
June 2017: Clinics in Laboratory Medicine
https://www.readbyqxmd.com/read/28457226/commentary-restarting-ntd-programme-activities-after-the-ebola-outbreak-in-liberia
#11
Brent C Thomas, Karsor Kollie, Benjamin Koudou, Charles Mackenzie
It is widely known that the recent Ebola Virus Disease (EVD) in West Africa caused a serious disruption to the national health system, with many of ongoing disease focused programmes, such as mass drug administration (MDA) for onchocerciasis (ONC), lymphatic filariasis (LF) and schistosomiasis (SCH), being suspended or scaled-down. As these MDA programmes attempt to restart post-EVD it is important to understand the challenges that may be encountered. This commentary addresses the opinions of the major health sectors involved, as well as those of community members, regarding logistic needs and challenges faced as these important public health programmes consider restarting...
May 1, 2017: Infectious Diseases of Poverty
https://www.readbyqxmd.com/read/28446173/impact-of-the-ebola-outbreak-on-routine-immunization-in-western-area-sierra-leone-a-field-survey-from-an-ebola-epidemic-area
#12
Xiaojin Sun, T T Samba, Jianyi Yao, Wenwu Yin, Lin Xiao, Fuqiang Liu, Xiaoqiang Liu, Jikun Zhou, Zengqiang Kou, Hongwei Fan, Hao Zhang, Aqnes Williams, Paul M Lansana, Zundong Yin
BACKGROUND: Since March 2014, the Ebola Virus Disease (EVD) outbreak in West Africa disrupted health care systems - especially in Guinea, Liberia and Sierra Leone - with a consequential stress on the area's routine immunization programs. To address perceived decreased vaccination coverage, Sierra Leone conducted a catch-up vaccination campaign during 24-27 April 2015. We conducted a vaccination coverage survey and report coverage estimates surrounding the time of the EVD outbreak and the catch-up campaign...
April 26, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28444452/ebola-virus-disease-in-children-during-the-2014-2015-epidemic-in-guinea-a-nationwide-cohort-study
#13
Mahamoud Sama Chérif, Nut Koonrungsesomboon, Diénaba Kassé, Sékou Ditinn Cissé, Saliou Bella Diallo, Fatoumata Chérif, Facély Camara, Alpha Koné, Eleonor Fundan Avenido, Mandiou Diakité, Mamadou Pathé Diallo, Edouard Le Gall, Mohamed Cissé, Juntra Karbwang, Kenji Hirayama
The most recent epidemic of Ebola virus disease (EVD) has resulted in more than 11,000 deaths in West Africa. It has threatened child health in the affected countries, including Guinea. This nationwide retrospective cohort study included all children under 20 years of age with laboratory-confirmed EVD in Guinea during the 2014-2015 Ebola outbreak for analysis. Of 8,448 children with probable or suspected EVD, 695 cases were laboratory-confirmed EVD. The overall case fatality rate (CFR) was 62.9%. Pediatric patients with younger age had a significantly higher rate of death (adjusted OR = 0...
April 25, 2017: European Journal of Pediatrics
https://www.readbyqxmd.com/read/28440096/strategies-in-ebola-virus-disease-evd-diagnostics-at-the-point-of-care
#14
Chad T Coarsey, Nwadiuto Esiobu, Ramswamy Narayanan, Mirjana Pavlovic, Hadi Shafiee, Waseem Asghar
Ebola virus disease (EVD) is a devastating, highly infectious illness with a high mortality rate. The disease is endemic to regions of Central and West Africa, where there is limited laboratory infrastructure and trained staff. The recent 2014 West African EVD outbreak has been unprecedented in case numbers and fatalities, and has proven that such regional outbreaks can become a potential threat to global public health, as it became the source for the subsequent transmission events in Spain and the USA. The urgent need for rapid and affordable means of detecting Ebola is crucial to control the spread of EVD and prevent devastating fatalities...
April 25, 2017: Critical Reviews in Microbiology
https://www.readbyqxmd.com/read/28439448/spatial-determinants-of-ebola-virus-disease-risk-for-the-west-african-epidemic
#15
Kate Zinszer, Kathryn Morrison, Aman Verma, John S Brownstein
INTRODUCTION: Although many studies have investigated the probability of Ebola virus disease (EVD) outbreaks while other studies have simulated the size and speed of EVD outbreaks, few have investigated the environmental and population-level predictors of Ebola transmission once an outbreak is underway. Identifying strong predictors of transmission could help guide and target limited public health resources during an EVD outbreak. We examined several environmental and population-level demographic predictors of EVD risk from the West African epidemic...
March 31, 2017: PLoS Currents
https://www.readbyqxmd.com/read/28439390/nosocomial-pseudomonas-putida-meningitis-a-case-report-and-literature-review
#16
Fahmi Yousef Khan, Mohammed AbuKamar, Deshmukh Anand
We report a case of Pseudomonas putida meningitis in a 26-year-old Nepalese man who was admitted to Hamad General Hospital with epidermoid cyst for drainage. Ommaya reservoir was placed into the cyst for drainage and externalventricular drainage (EVD) was performed. After four days, the patient was transferred to the ward in stable condition. His weakness resolved partially and headache severity decreased. After three days, the patient developed fever and headache severity increased with deterioration of consciousness level...
March 2017: Oman Medical Journal
https://www.readbyqxmd.com/read/28437843/a-bayesian-belief-network-model-assessing-the-risk-to-wastewater-workers-of-contracting-ebola-virus-disease-during-an-outbreak
#17
Joseph W Zabinski, Kelsey J Pieper, Jacqueline MacDonald Gibson
During an outbreak of Ebola virus disease (EVD), hospitals' connections to municipal wastewater systems may provide a path for patient waste bearing infectious viral particles to pass from the hospital into the wastewater treatment system, potentially posing risks to sewer and wastewater workers. To quantify these risks, we developed a Bayesian belief network model incorporating data on virus behavior and survival along with structural characteristics of hospitals and wastewater treatment systems. We applied the model to assess risks under several different scenarios of workers' exposure to wastewater for a wastewater system typical of a mid-sized U...
April 24, 2017: Risk Analysis: An Official Publication of the Society for Risk Analysis
https://www.readbyqxmd.com/read/28434944/dose-dependent-t-cell-dynamics-and-cytokine-cascade-following-rvsv-zebov-immunization
#18
Christine Dahlke, Rahel Kasonta, Sebastian Lunemann, Verena Krähling, Madeleine E Zinser, Nadine Biedenkopf, Sarah K Fehling, My L Ly, Anne Rechtien, Hans C Stubbe, Flaminia Olearo, Saskia Borregaard, Alen Jambrecina, Felix Stahl, Thomas Strecker, Markus Eickmann, Marc Lütgehetmann, Michael Spohn, Stefan Schmiedel, Ansgar W Lohse, Stephan Becker, Marylyn M Addo
BACKGROUND: The recent West African Ebola epidemic led to accelerated efforts to test Ebola vaccine candidates. As part of the World Health Organisation-led VSV Ebola Consortium (VEBCON), we performed a phase I clinical trial investigating rVSV-ZEBOV (a recombinant vesicular stomatitis virus-vectored Ebola vaccine), which has recently demonstrated protection from Ebola virus disease (EVD) in phase III clinical trials and is currently in advanced stages of licensing. So far, correlates of immune protection are incompletely understood and the role of cell-mediated immune responses has not been comprehensively investigated to date...
April 5, 2017: EBioMedicine
https://www.readbyqxmd.com/read/28420487/personal-protective-equipment-solution-for-uk-military-medical-personnel-working-in-an-ebola-virus-disease-treatment-unit-in-sierra-leone
#19
P Reidy, T Fletcher, C Shieber, J Shallcross, H Towler, M Ping, L Kenworthy, N Silman, E Aarons
The combination of personal protective equipment (PPE) together with donning and doffing protocols was designed to protect British and Canadian military medical personnel in the Kerry Town Ebola Treatment Unit (ETU) in Sierra Leone. The PPE solution was selected to protect medical staff from infectious risks, notably Ebola virus, and chemical (hypochlorite) exposure. PPE maximized dexterity, enabled personnel to work in hot temperatures for periods of up to 2h, protected mucosal membranes when doffing outer layers, and minimized potential contamination of the doffing area with infectious material by reducing the requirement to spray PPE with hypochlorite...
March 18, 2017: Journal of Hospital Infection
https://www.readbyqxmd.com/read/28416172/epidemiology-of-ebolavirus-disease-evd-and-occupational-evd-in-health-care-workers-in-sub-saharan-africa-need-for-strengthened-public-health-preparedness
#20
REVIEW
Nlandu Roger Ngatu, Ntumba Jean-Marie Kayembe, Elayne Kornblatt Phillips, Joa Okech-Ojony, Masika Patou-Musumari, Mukunda Gaspard-Kibukusa, Ndona Madone-Mandina, Mabasi Godefroid-Mayala, Lubogo Mutaawe, Casimir Manzengo, Dimosi Roger-Wumba, Sayumi Nojima
Ebolavirus disease (EVD) is a severe contagious disease in humans, and health care workers (HCW) are at risk of infection when caring for EVD patients. This paper highlights the epidemiologic profile of EVD and its impact on the health care workforce in Africa. A documentary study was conducted which consisted of a review of available literature regarding the epidemiology of EVD, occupational EVD (OEVD), and work safety issues in Sub-Saharan Africa; the literature findings are enriched by field experiences from the authors...
April 13, 2017: Journal of Epidemiology
keyword
keyword
94058
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"