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JOURNAL ARTICLE
Lohuwa Mamudu, Jinyi Li, Archana J McEligot, Michele Wood, Pimbucha Rusmevichientong, Erasmus Tetteh-Bator, Abdul-Nasah Soale, James D Fortenberry, Faustine Williams
OBJECTIVE: With cancer the second deadliest disease in the world, worry about cancer can have mental health or psychiatric implications. This study examines the prevalence, differences, and influence of cancer worry (CW), its interaction effect with age, and other confounders on self-reported depressive symptoms (SRDS) among adult males and females in the US. METHODS: We utilized a nationally representative sample data of 2,950 individuals (males = 1,276; females = 1,674) from Cycle 4 of the Health Information National Trends Survey 5 (HINTS 5) 2020...
January 8, 2024: BMC Psychiatry
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JOURNAL ARTICLE
Anastase Dzudie, Patrice Tchendjou, Eveline Mboh Khan, Rogers Ajeh, Friedrich Thienemann, Appolinaire Tiam, Boris Tchounga, Joseph Fokam, Clement Ndongmo, Peter Vanes Ebasone, Gabriel Mabou, Andre Pascal Goura, Emile Nforbih Shu, Tshimwanga Katayi, Pascal Atanga Nji, Marc Lionel Ngamani, Clarisse Lengouh, Felicite Naah Tabala, Ebako Ndip Takem, Albert Bakor, Lorraine Guedem Nekame, Tatiana Djikeussi, Ezechiel Ngoufack Jagni Semengue, Kandel Tebong Fon, Collins Chenwi, Judith Lainsi Nasah, George Njie Ngeke, Masha Roland Tasha, Nicoline Ndiforkwah, Grace Nyemb, Emmanuel Nshom, Clovis N Draman, Charlotte Ayima Wenze, Leonie Simo, Gilles Ndayisaba, Walters Kum Kang, Alex Durand Nka, Boris Youngui Tchakounte, Simplice Lekeumo, Esther Neba, Nyenty Agbornkwai, Therese Abong Bwemba, Pius Tih Muffih, Anne Cecile Zoung-Kany Bisseck, Louis Richard Njock
Cameroon is committed to reaching HIV epidemic control through coordinated efforts by the Ministry of Public Health, the National AIDS Control Committee, bilateral/multilateral institutions and implementing partners. The third edition of the Cameroon HIV Research Forum (CAM-HERO) was held in Kribi from December 1st to 3rd , 2022, with the theme "Research for Health Care and Policy on HIV/AIDS." The conference brought together local and international scientists and clinicians, policymakers, and regulatory authorities to 1) disseminate HIV research findings and HIV policy; 2) foster operational research collaboration; 3) build research capacity through training on basics of research methods and CAM-HERO young investigator Awards; and 4) initiate a guideline for promoting HIV/AIDS research in Cameroon...
2023: Pan African Medical Journal
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JOURNAL ARTICLE
Daniel Santana, Alejandra Mosteiro, Laura Llull, Miquel Massons, Luigi Zattera, Gabriel Pujol-Fontrodona, Mariano Werner, Ramón Torné, Sergio Amaro, Angel Chamorro
INTRODUCTION: Stroke Units (SU) have been suggested as an alternative to Intensive Care units (ICU) for initial admission of low-grade non-aneurysmal spontaneous subarachnoid haemorrhage (naSAH). We hypothesised that the incidence of in-hospital complications and long-term clinical outcomes in low-grade naSAH patients would be comparable in both settings, and that a cost-minimisation analysis would favour the use of SU. PATIENTS AND METHODS: Retrospective, single-centre study at a third-level stroke-referral hospital, including low-grade spontaneous naSAH patients with WFNS 1-2...
September 25, 2023: European Stroke Journal
#4
JOURNAL ARTICLE
Chiara Ragaglini, Matteo Foschi, Federico De Santis, Anna Laura Molliconi, Francesco Conversi, Enrico Colangeli, Raffaele Ornello, Simona Sacco
INTRODUCTION: Incidence of atraumatic subarachnoid hemorrhage (SAH) is decreasing over time and its treatment is changing. We reported epidemiologic data on aneurysmal (a-) and non-aneurysmal (na-) SAH over 10 years. PATIENTS AND METHODS: Our prospective population-based registry included patients with first-ever SAH occurring from January 2011 to December 2020. Clinical and neuroimaging records were screened to evaluate the presence and location of intracranial aneurysms, to identify naSAH subtypes and to retrieve information on surgical treatments...
September 4, 2023: European Stroke Journal
#5
JOURNAL ARTICLE
Christina Wolfert, Christoph J Maurer, Björn Sommer, Kathrin Steininger, Stefan Motov, Maximilian-Niklas Bonk, Philipp Krauss, Ansgar Berlis, Ehab Shiban
Perimesencephalic nonaneurysmal subarachnoid hemorrhage (NASAH) is a rare type of subarachnoid hemorrhage (SAH), usually associated with minor complications compared to aneurysmal SAH. Up to date, data is scarce and consensus on therapeutic management and follow-up diagnostics of NASAH is often missing. This survey aims to evaluate the clinical management among neurosurgical departments in Germany. 135 neurosurgical departments in Germany received a hardcopy questionnaire. Encompassing three case vignettes with minor, moderate and severe NASAH on CT-scans and questions including the in-hospital treatment with initial observation, blood pressure (BP) management, cerebral vasospasm (CV) prophylaxis and the need for digital subtraction angiography (DSA)...
August 7, 2023: Scientific Reports
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JOURNAL ARTICLE
Zahra Sadat Mortazavi, Alireza Zandifar, Jorge Du Ub Kim, Luis Octavio Tierradentro-García, Mehrnaz Shakarami, Farzam Dashti Zamharir, Maryam Hadipour, Marjan Oustad, Elham Shafiei, Seyedeh Zahra Tara, Peyman Shirani, Hamed Asadi, Arastoo Vossough, Mohammad Saadatnia
INTRODUCTION: Subarachnoid hemorrhage (SAH) is one of the world's most life-threatening types of stroke. SAH can be classified into two main categories, aneurysmal (aSAH) and non-aneurysmal SAH (naSAH). In the present study, we aimed to prospectively evaluate SAH and its subcategories incidences, risk factors (RF), complications and outcomes in central Iran. METHODS: All SAH patients diagnosed between 2016-2020 were included in Isfahan SAH Registry (ISR). Demographic, clinical characteristics, incidence rates (based on age categories), and laboratory/imaging findings were collected and compared between aSAH and naSAH subgroups...
April 4, 2023: World Neurosurgery
#7
JOURNAL ARTICLE
Christina Wolfert, Christoph J Maurer, Ansgar Berlis, Hauke Schneider, Kathrin Steininger, Stefan Motov, Philipp Krauss, Björn Sommer, Ehab Shiban
Non-aneurysmal subarachnoid hemorrhage (NASAH) is rare and mostly benign. However, complications such as cerebral vasospasm (CV), delayed cerebral ischemia (DCI), or post-hemorrhagic hydrocephalus (HC) may worsen the prognosis. The aim of this study was to evaluate the rate of these complications comparing perimesencephalic (PM) and non-perimesencephalic (NPM) SAH. Monocentric, retrospective analysis of patients diagnosed with NASAH from 01/2010 to 01/2021. Diagnosis was set only if vascular pathologies were excluded in at least one digital subtraction angiography, and NASAH was confirmed by cranial computed tomography (cCT) or lumbar puncture (LP)...
December 22, 2022: Neurosurgical Review
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JOURNAL ARTICLE
Abdul-Nasah Soale
Many existing sufficient dimension reduction methods are designed for regression with predictors that are elliptically distributed, which limits their application in real data analyses. Projection expectile regression (PER) is proposed as a new linear sufficient dimension reduction method for handling complex predictor structures, which includes continuous, discrete, and mixed predictor variables. PER requires the link function between the response and the predictor to be monotone, but not necessarily smooth, which makes it suitable for handling stratified response surfaces...
April 2023: Computational Statistics & Data Analysis
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JOURNAL ARTICLE
Tingting Yu, Zhengyang Wang
BACKGROUND: Patients who suffer from non-traumatic non-aneurysmal subarachnoid hemorrhage (naSAH) episodes still face a risk of clinical complications and poor outcome. As the systemic inflammatory response index (SIRI) has recently been shown to offer value as a tool capable of predicting aneurysmal SAH (aSAH) patient outcomes, this study was designed to gauge SIRI prognostic utility in naSAH patients. METHODS: Clinical findings and outcome data for 111 naSAH patients were analyzed, with patients being separated into high- and low-SIRI groups...
December 2022: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
#10
JOURNAL ARTICLE
Dan Laukka, Juri Kivelev, Riitta Rautio, Johanna Kuhmonen, Matias Sinisalo, Jaakko Rinne, Melissa Rahi
BACKGROUND: Perimesencephalic and nonperimesencephalic nonaneurysmal subarachnoid hemorrhage (PM-naSAH and NPM-naSAH) have a different bleeding pattern and clinical course. The etiology and risk factors for PM-naSAH and NPM-naSAH are unclear. The objective of this study was to compare risk factors and triggering events between PM-naSAH and NPM-naSAH. METHODS: We reviewed retrospectively all patients (n = 3475) who had undergone cerebral digital subtraction angiography between 2003 and 2020 at our tertiary hospital...
September 1, 2022: Brain and Behavior
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JOURNAL ARTICLE
The relationship between non-aneurysmal spontaneous subarachnoid hemorrhage and basilar tip anatomy.
Hangeul Park, Young-Je Son, Noah Hong, Seung Bin Kim
OBJECTIVE: Non-aneurysmal spontaneous subarachnoid hemorrhage (NASAH) has a good prognosis, but its cause has not been clearly identified. In this study, we assessed the clinical and radiological features of NASAH and suggested an anatomical relationship between the basilar tip anatomy and NASAH. METHODS: From August 2013 to May 2020, 21 patients were diagnosed with NASAH at our institution. We evaluated the clinical features of NASAH. NASAH was classified into a perimesencephalic pattern and aneurysmal pattern according to the distribution of hemorrhage based on initial brain computed tomography...
September 2022: Journal of Cerebrovascular and Endovascular Neurosurgery
#12
JOURNAL ARTICLE
Yuan Yuan, Jingjiong Chen, Yaxuan Zhang, Fei Zhao, Yanyu Zhai, Xiaofeng Xu, Lixia Xue, Yuwu Zhao, Hongmei Wang
BACKGROUND: Subarachnoid hemorrhage (SAH) is a devastating neurological disease associated with high rates of mortality and disability. Aneurysms are the main cause of non-traumatic subarachnoid hemorrhages. However, non-traumatic non-aneurysmal subarachnoid hemorrhage (naSAH), another clinical type of SAH, has been poorly studied for its prognosis and risk factors. METHOD AND RESULT: We collected demographic and clinical variables for 126 naSAH and 89 aneurysmal subarachnoid hemorrhage (aSAH) patients, including age and gender; hospitalization days; hematological indicators; clinical score scales; past medical history; and personal history...
July 6, 2022: Biomolecules
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JOURNAL ARTICLE
Manuel Angermann, Fidaa Jablawi, Maike Angermann, Catharina Conzen-Dilger, Gerrit A Schubert, Anke Höllig, Michael Veldeman, Arno Reich, Dimah Hasan, Hani Ridwan, Hans Clusmann, Martin Wiesmann, Omid Nikoubashman
OBJECTIVE: To demonstrate the clinical outcome of patients with nonperimesencephalic subarachnoid hemorrhage (npSAH) compared with patients with aneurysmal SAH (aSAH) and perimesencephalic SAH (pSAH) and to evaluate predictive value of various clinical and radiological findings in patients with npSAH. METHODS: We retrospectively identified patients with SAH who presented at our institution between 2009 and 2018. We analyzed demographic and clinical data and outcomes...
September 2022: World Neurosurgery
#14
Shyle Mehta, Abhijith Bathini, Anwesha Dubey, Awinita Barpujari, Ahmad Kassem, Mohanad Sulaiman, Mandy Binning
We present a case series of two patients who developed unilateral cranial nerve III (CNIII) palsy following non-aneurysmal SAH (NASAH). Subarachnoid hemorrhage (SAH) can present with various signs and symptoms. Early diagnosis is paramount to determine treatment course. Thus, clinicians must be aware of the variable clinical presentations of this condition. Two patients were admitted to a single institution for SAH. Patient 1, 52-year-old male, presented with headache, left eye ptosis, and painless diplopia...
September 2022: Journal of Cerebrovascular and Endovascular Neurosurgery
#15
JOURNAL ARTICLE
Pui Man Rosalind Lai, Isaac Ng, William B Gormley, Nirav Patel, Kai U Frerichs, M Ali Aziz-Sultan, Rose Du
OBJECTIVE: Spontaneous subarachnoid hemorrhage is often due to rupture of an intracranial aneurysm, but some patients present with no identifiable source. Increased incidence of nonaneurysmal subarachnoid hemorrhage (naSAH) has been reported over time. METHODS: We performed a retrospective analysis of naSAH from 2008-2017 to determine the rate of naSAH change over time and its association with cannabis use. Univariable and multivariable regression analyses were performed to study the trend over time, radiographic patterns of hemorrhage, and clinical outcome at the time of discharge...
October 2021: World Neurosurgery
#16
JOURNAL ARTICLE
Giacomo Bertolini, Alessia Fratianni, Alberto Luca Messina, Enrico Epifani, Matteo Fantoni, Pellegrino Crafa, Diego Mazzatenta, Roberto Menozzi, Ermanno Giombelli
Spontaneous non-aneurysmal subarachnoid haemorrhage (naSAH) is an unusual finding that could be burdened by significant mortality and morbidity rates. Rare pathologies and delayed diagnosis could be advocated as responsible of unfavourable outcomes. Herein, we describe an exceedingly rare giant lumbar spinal hemangioblastoma (80 × 23 mm) presenting as an intracranial naSAH. Based on our radiological and clinical findings a pathophysiological hypothesis linking intracranial naSAH to venous hypertension was discussed for the first time even among lumbar spinal tumors...
June 18, 2021: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
#17
Sepide Kashefiolasl, Marlies Wagner, Nina Brawanski, Volker Seifert, Stefan Wanderer, Lukas Andereggen, Juergen Konczalla
The efficacy of statin-treatment in aneurysmal subarachnoid hemorrhage (SAH) remains controversial. We aimed to investigate the effects of statin-treatment in non-aneurysmal (na)SAH in accordance with animal research data illustrating the pathophysiology of naSAH. We systematically searched PubMed using PRISMA-guidelines and selected experimental studies assessing the statin-effect on SAH. Detecting the accordance of the applied experimental models with the pathophysiology of naSAH, we analyzed our institutional database of naSAH patients between 1999 and 2018, regarding the effect of statin treatment in these patients and creating a translational concept...
2021: Frontiers in Neurology
#18
JOURNAL ARTICLE
Pui Man Rosalind Lai, Isaac Ng, William B Gormley, Nirav J Patel, Kai U Frerichs, M Ali Aziz-Sultan, Rose Du
BACKGROUND: Subarachnoid hemorrhage (SAH) from an intracranial aneurysmal rupture is the most common nontraumatic etiology for SAH, but up to 15% of patients with SAH have no identifiable source. OBJECTIVE: To assess familial predisposition to spontaneous nonaneurysmal SAH (naSAH) and to evaluate whether family history affects the severity of presentation and prognosis of this condition. METHODS: We conducted a retrospective analysis of all spontaneous SAH with negative digital subtraction angiography from 2004 to 2018...
October 5, 2020: Neurosurgery
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JOURNAL ARTICLE
Kamila Janmohamed, Abdul-Nasah Soale, Laura Forastiere, Weiming Tang, Yongjie Sha, Jakob Demant, Edoardo Airoldi, Navin Kumar
BACKGROUND: The COVID-19 outbreak was designated a global pandemic on March 11, 2020. The relationship between vaping and contracting COVID-19 is unclear, and information on the internet is conflicting. There is some scientific evidence that vaping cannabidiol (CBD), an active ingredient in cannabis that is obtained from the hemp plant, or other substances is associated with more severe manifestations of COVID-19. However, there is also inaccurate information that vaping can aid COVID-19 treatment, as well as expert opinion that CBD, possibly administered through vaping, can mitigate COVID-19 symptoms...
October 30, 2020: Journal of Medical Internet Research
#20
JOURNAL ARTICLE
Midhun Mohan, Abdurrahman I Islim, Fahid T Rasul, Ola Rominiyi, Ruth-Mary deSouza, Michael T C Poon, Aimun A B Jamjoom, Angelos G Kolias, Julie Woodfield, Krunal Patel, Aswin Chari, Ramez Kirollos
BACKGROUND: In patients with spontaneous subarachnoid haemorrhage (SAH), a vascular cause for the bleed is not always found on initial investigations. This study aimed to systematically evaluate the delayed investigation strategies and clinical outcomes in these cases, often described as "non-aneurysmal" SAH (naSAH). METHODS: A systematic review was performed in concordance with the PRISMA checklist. Pooled proportions of primary outcome measures were estimated using a random-effects model...
October 2019: Acta Neurochirurgica
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