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Yuichi Mukai, Toshihiko Agatsuma, Gen Ideura
Idiopathic pulmonary haemosiderosis (IPH) is a diagnosis of exclusion, which is characterized by persistent or recurrent episodes of alveolar haemorrhage. Early diagnosis of IPH, especially in the case of first-time manifestation, is challenging because previous episodes of alveolar haemorrhage are often difficult to prove. Repeated episodes of alveolar haemorrhage can result in chronic iron-deficient anaemia and irreversible interstitial fibrosis; thus, early recognition and intervention are desirable in terms of clinical outcome...
April 2018: Respirology Case Reports
Yasuhiro Fujiwara, Hirotoshi Maruyama, Kanako Toyomaru, Yuri Nishizaka, Masahiro Fukamatsu
Magnetic resonance imaging (MRI) is widely used to detect carotid atherosclerotic plaques. Although it is important to evaluate vulnerable carotid plaques containing lipids and intra-plaque hemorrhages (IPHs) using T1 -weighted images, the image contrast changes depending on the imaging settings. Moreover, to distinguish between a thrombus and a hemorrhage, it is useful to evaluate the iron content of the plaque using both T1 -weighted and T2 *-weighted images. Therefore, a quantitative evaluation of carotid atherosclerotic plaques using T1 and T2 * values may be necessary for the accurate evaluation of plaque components...
March 6, 2018: Radiological Physics and Technology
Waleed Brinjikji, J Kevin DeMarco, Robert Shih, Giuseppe Lanzino, Alejandro A Rabinstein, Christopher A Hilditch, Patrick J Nicholson, John Huston
BACKGROUND: Carotid plaque imaging with MRI is becoming more commonplace, but practical challenges exist in performing plaque imaging with surface coils. PURPOSE: To compare the diagnostic performance of a carotid plaque MRI protocol using a standard neurovascular coil (Neurovascular Coil Protocol) to a higher-resolution carotid plaque MRI using carotid surface coils (Surface Coil Protocol) in characterizing carotid plaque. STUDY TYPE: Prospective study comparing two MR techniques in plaque characterization...
February 25, 2018: Journal of Magnetic Resonance Imaging: JMRI
Luis C Ascanio, Georgios A Maragkos, Brett C Young, Myles D Boone, Ekkehard M Kasper
Stroke in pregnant women has a mortality rate of 1.4 deaths per 100,000 deliveries. Vascular malformations are the most common cause of hemorrhagic stroke in this population; preeclampsia and other risk factors have been identified. However, nearly a quarter of strokes have an undeterminable cause. Spontaneous intracranial hemorrhage (ICH) is less frequent but results in significant morbidity. The main objective of this study is to review the literature on pregnant patients who had a spontaneous ICH. A systematic review of the literature was conducted on PubMed and the Cochrane library from January 1992 to September 2016 following the PRISMA guidelines...
February 23, 2018: Neurocritical Care
Etsu Suzuki, Hiroyuki Imuta, Daishi Fujita, Masao Takahashi, Shigeyoshi Oba, Arihiro Kiyosue, Hiroaki Nishimatsu
BACKGROUND: Intraplaque hemorrhage (IPH) has been implicated in plaque instability and rupture in atherosclerotic lesions, although the mechanisms by which IPH progresses remain largely unknown. In this study, apolipoprotein E-deficient mice with carotid artery ligation and cuff placement around the artery were used, and pro-inflammatory cytokines that are implicated in IPH were analyzed.Methods and Results:The expression of interleukin-1β (IL-1β) increased significantly following cuff placement compared with mice with carotid artery ligation alone...
February 22, 2018: Circulation Journal: Official Journal of the Japanese Circulation Society
Rajeev Khanna, Shiv Kumar Sarin
BACKGROUND: Idiopathic portal hypertension (IPH) and extrahepatic portal venous obstruction (EHPVO) are non-cirrhotic vascular causes of portal hypertension (PHT). Variceal bleed and splenomegaly are the commonest presentations. AIM: The present review is intended to provide the existing literature on etiopathogenesis, clinical profile, diagnosis, natural history and management of IPH and EHPVO. RESULTS: IPH and EHPVO are both characterized by normal hepatic venous pressure gradient, moderate to massive splenomegaly with preserved liver synthetic functions...
February 20, 2018: Hepatology International
Jai Jai Shiva Shankar, Namita Sinha
BACKGROUND: The imaging appearance of neoplastic hematoma can be complicated by the presence of a large hematoma, even on magnetic resonance imaging (MRI). We describe the role of MR perfusion (MRP) in detecting neoplastic hematomas in patients with intraparenchymal hematoma (IPH). MATERIAL AND METHODS: A retrospective review was performed for consecutive patients with IPH, where MRP was performed. Routine, post-gadolinium MRI and MRP were analyzed. All patients were either operated on for evacuation of IPH or followed up on imaging...
February 7, 2018: Clinical Neuroradiology
V Montiel, M Alfonso, C Villas, A Valentí
BACKGROUND: Exostoses at the base of the distal phalanx of the great toe are usually asymptomatic. The literature has not generally considered them as the origin of a possible problem resulting from a pressure conflict between hallux and shoe (medial aspect) or second toe (lateral aspect) nor a potential complication of surgical correction of hallux valgus deformity. No studies, to our knowledge, have evaluated its possible correlation with other foot disorders. When one of these neglected exostoses became painful after surgical correction of hallux valgus, we decided to start a study to determine their possible origin, prevalence in daily practice and histo-pathological morphology...
November 13, 2017: Foot and Ankle Surgery: Official Journal of the European Society of Foot and Ankle Surgeons
Mengxing Sun, Qiyi Fang, Zhepeng Zhang, Dan Xie, Yilin Sun, Jian-Long Xu, Weiwei Li, Tianling Ren, Yanfeng Zhang
Inorganic cesium lead halide perovskites have attracted intense interest in optoelectronic applica-tions due to the relatively stable performance in air. However, most reported inorganic perov-skite-based optoelectronic devices exhibit low photosensitivity which greatly hinders their further applications. Here, we firstly demonstrate a hybrid optical structure which combines the n-type thin film InGaZnO and the all-inorganic perovskite nanowires of CsPbBr3 together. By this way, excellent optical and electrical properties such as a low dark current of 10-10 A (at -5V), a high Iph/Idark of 1...
February 5, 2018: ACS Applied Materials & Interfaces
Thomas J Cusack, J Ricardo Carhuapoma, Wendy C Ziai
PURPOSE OF REVIEW: Spontaneous intraparenchymal hemorrhage (IPH) is a prominent challenge faced globally by neurosurgeons, neurologists, and intensivists. Over the past few decades, basic and clinical research efforts have been undertaken with the goal of delineating biologically and evidence-based practices aimed at decreasing mortality and optimizing the likelihood of meaningful functional outcome for patients afflicted with this devastating condition. Here, the authors review the medical and surgical approaches available for the treatment of spontaneous intraparenchymal hemorrhage, identifying areas of recent progress and ongoing research to delineate the scope and scale of IPH as it is currently understood and treated...
February 3, 2018: Current Treatment Options in Neurology
Jinseong Lee, Jinsang Kil, Dae-Won Kim, Sung-Don Kang
Objective: Measurement of the degree of stenosis is not enough to decide on the treatment strategy for patients with carotid stenosis. Plaque morphology examination is needed for such a decision-making. Thus, we evaluated the usefulness of plaque magnetic resonance imaging (MRI) to decide on the modality of treatment for patients with carotid atherosclerotic plaques. Materials and Methods: Fifteen patients presenting with carotid stenosis between 2014 and 2016 were included...
December 2017: Journal of Cerebrovascular and Endovascular Neurosurgery
Yuvasree Purusothaman, Nagamalleswara Rao Alluri, Arunkumar Chandrasekhar, Venkateswaran Vivekananthan, Sang-Jae Kim
A feasible, morphological influence on photoresponse behavior of ZnO microarchitectures such as microwire (MW), coral-like microstrip (CMS), fibril-like clustered microwire (F-MW) grown by one-step carrier gas/metal catalyst "free" vapor transport technique is reported. Among them, ZnO F-MW exhibits higher photocurrent (IPh ) response, i.e., IPh/ZnO F-MW > IPh/ZnO CMS > IPh/ZnO MW . The unique structural alignment of ZnO F-MW has enhanced the IPh from 14.2 to 186, 221, 290 µA upon various light intensities such as 0 to 6, 11, 17 mW cm-2 at λ405 nm ...
January 29, 2018: Small
Xing Zhou, Xiaozong Hu, Shasha Zhou, Hongyue Song, Qi Zhang, Lejing Pi, Liang Li, Huiqiao Li, Jingtao Lü, Tianyou Zhai
van der Waals (vdW) heterostructures based on atomically thin 2D materials have led to a new era in next-generation optoelectronics due to their tailored energy band alignments and ultrathin morphological features, especially in photodetectors. However, these photodetectors often show an inevitable compromise between photodetectivity and photoresponsivity with one high and the other low. Herein, a highly sensitive WSe2 /SnS2 photodiode is constructed on BN thin film by exfoliating each material and manually stacking them...
January 8, 2018: Advanced Materials
M A Bashar, Sonu Goel
Background: A Sub-Centre (SC) is most peripheral and first point of contact between the primary healthcare system and the community in the rural areas. The success of any nationwide program largely depends on well-functioning SCs providing services of acceptable standards to people. Indian Public Health Standards (IPHS) for SCs was prepared keeping in view the minimum standards required to provide quality and need sensitive health care to the community. Materials and Methods: A cross-sectional study was conducted in Ambala District of Haryana to assess the availability of physical infrastructure, manpower, drugs and equipment in the SCs...
April 2017: Journal of Family Medicine and Primary Care
Simon Duff, Mirjam Nampweya, Jeremy Tree
Intimate partner violence (IPV) is a global social problem, which may result in intimate partner homicide (IPH). Much of the research concerned with IPH is based in developed nations and as such this study explored men's explanations for IPH (known locally as "passion killing") in the Namibian context by interviewing 10 individuals who were convicted and sentenced for the murder of their female intimate partners. A semi-structured interview was conducted with the offenders and the resulting transcripts were analyzed by Interpretative Phenomenological Analysis...
July 1, 2017: Journal of Interpersonal Violence
Aidin Parnia, Nikoo Yamani, Ahmadreza Zamani, Shervin Badihian, Navid Manouchehri, Maryam Fakhri
Background: A serious challenge to educate health staff for public health is to appear encouraging enough to persuade them for learning issues on this field and implementing new educational methods and innovative ways. Iran International Public Health Summer School (IPHS) made an effort to provide medical sciences students with a fortune to get familiar with and involved in public health. This study intended to evaluate the efficacy of this event. Materials and Methods: This cross-sectional study was performed in March-April 2015 by the help of an electronic self-administered questionnaire filled out by 49 Iranian participants 6 months after IPHS2014...
2017: Advanced Biomedical Research
Yi-Chun Lin, Harn-Shen Chen
INTRODUCTION: The pattern of glucose levels during an oral glucose tolerance test (OGTT) may be useful for predicting diabetes or cardiovascular disease (CVD). Our aim was to determine whether the time to peak glucose during the OGTT is associated with CVD risk scores and diabetes. METHODS: Individuals with impaired fasting glucose (IFG) were enrolled in this observational study. Participants were grouped by the measured time to peak glucose (30, 60, 90 and 120 min) during the 75g OGTT...
2017: PloS One
Wataru Suzuki, Hiroaki Kotani, Tomoya Ishizuka, Yoshihito Shiota, Kazunari Yoshizawa, Takahiko Kojima
The two-electron reduction of a diprotonated dodecaphenylporphyrin derivative by Na2 S2 O4 gave a corresponding isophlorin (Iph) selectively. Formation of Iph was confirmed by spectroscopic measurements and the isolation of tetramethylated Iph. Further reduction of Iph proceeded to form an unprecedented four-electron-reduced porphyrin (IphH2 ), which was fully characterized by spectroscopic and X-ray crystallographic analysis. IphH2 , with a unique conformation, could be oxidized to reproduce the starting porphyrin, resulting in a proton-coupled four-electron reversible redox system...
February 12, 2018: Angewandte Chemie
A Birke, M Aluja
The preference-performance hypothesis (PPH) has widely been used to explain host exploitation patterns by phytophagous insects. However, this hypothesis often fails in the case of polyphagous species when compared with specialists. One explanation, validated by the information-processing hypothesis (IPH), considers that polyphagous insects are unable to process a large array of cues, which hinders females from distinguishing between high- and low- quality hosts. Here we analyzed Anastrepha ludens female host preference and offspring performance, and tested if neuronal limitations could possibly play a role in the incapacity of the polyphagous A...
December 4, 2017: Bulletin of Entomological Research
April M Zeoli, Alexander McCourt, Shani Buggs, Shannon Frattaroli, David Lilley, Daniel W Webster
In this research, we estimate the association of firearm restrictions for domestic violence offenders with intimate partner homicides (IPHs), based on the strength of the policies. We posit that the association of firearm laws with IPHs depends on the laws': 1) breadth of coverage of high-risk individuals and situations restricted; 2) power to compel firearm surrender or removal from prohibited persons; and 3) systems of accountability that prevent prohibited persons from obtaining guns. We conducted a quantitative policy evaluation using annual state-level data from 1980 through 2013 for 45 US states...
November 29, 2017: American Journal of Epidemiology
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