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musculoskeletal disorders

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https://www.readbyqxmd.com/read/29330560/altered-bone-remodeling-in-psoriatic-disease-new-insights-and-future-directions
#1
REVIEW
Ananta Paine, Christopher Ritchlin
Psoriatic arthritis (PsA) is an inflammatory rheumatic disorder that occurs in patients with psoriasis and predominantly affects musculoskeletal structures, skin, and nails. The etiology of PsA is not well understood but evidence supports an interplay of genetic, immunologic, and environmental factors which promote pathological bone remodeling and joint damage in PsA. Localized and systemic bone loss due to increased activity of osteoclasts is well established in PsA based on animal models and translational studies...
January 12, 2018: Calcified Tissue International
https://www.readbyqxmd.com/read/29328683/fatigue-and-related-comorbidities-active-component-u-s-armed-forces-2007-2016
#2
Robert M Guido, Shauna Stahlman, Saixia Ying
Fatigue is a common complaint in the civilian population and may be a presenting symptom of more serious physical and mental disorders. Data from the Defense Medical Surveillance System (DMSS) were utilized to characterize the incidence and burden of fatigue in active component military members from 1 January 2007 through 31 December 2016. A subanalysis of 3 years within this surveillance period (2012-2014) was also conducted to assess the burden of comorbidities related to incident fatigue and the strength of the association between fatigue and selected comorbidities...
December 2017: MSMR
https://www.readbyqxmd.com/read/29326058/sleep-architecture-is-altered-in-the-reserpine-induced-fibromyalgia-model-in-ovariectomized-rats
#3
Alberto Hernandez-Leon, Alonso Fernández-Guasti, Adrián Martínez, Francisco Pellicer, María Eva González-Trujano
Fibromyalgia (FM) is a musculoskeletal chronic pain syndrome with various concomitant symptoms like sleep disorders. FM patients are mainly women and menopause might play an important role in the altered processing of somatosensory information. Adverse effects and moderated efficacy of drugs promote treatment discontinuation by patients. Animal models of FM report pain and depression-like behaviors, but none of them have explored sleep disturbance as possible marker in the preclinic diagnostic. The aim of this study was to investigate alterations of the sleep architecture in the reserpine (RES)-induced FM model in ovarectomized (OVX) rats...
January 8, 2018: Behavioural Brain Research
https://www.readbyqxmd.com/read/29325902/which-data-should-be-tracked-in-forward-dynamic-optimisation-to-best-predict-muscle-forces-in-a-pathological-co-contraction-case
#4
Colombe Bélaise, Benjamin Michaud, Fabien Dal Maso, Katja Mombaur, Mickaël Begon
The choice of the cost-function for predicting muscle forces during a movement remains a challenge, especially in patients with neuromuscular disorders. Forward dynamics-based optimisations mainly track joint kinematics or torques, combined with a least-excitation criterion. Tracking marker trajectories and/or electromyography (EMG) has rarely been proposed. Our objective was to determine the best tracking objective-function to accurately predict the upper-limb muscle forces. A musculoskeletal model was created and EMG was simulated to obtain a reference movement - a shoulder abduction...
January 4, 2018: Journal of Biomechanics
https://www.readbyqxmd.com/read/29325537/factors-associated-with-the-prevalence-of-back-pain-and-work-absence-in-shipyard-workers
#5
Seiji Watanabe, Toshiaki Takahashi, Jun Takeba, Hiromasa Miura
BACKGROUND: We conducted a questionnaire survey of shipyard workers to identify difficulties experienced due to orthopedic or musculoskeletal disorders. METHODS: The subjects were 375 workers (male, 361; female, 14) who worked for a single shipbuilding company. Questionnaire items covered the working environment, including work environment, working posture, and the weight of objects that the subject dealt with, as well as physical and lifestyle characteristics, namely smoking habits, drinking habits, sleeping hours, medications, exercise habits, and any weight gain of 20 kg or more since the age of 20...
January 11, 2018: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/29324727/frequent-exertion-and-frequent-standing-at-work-by-industry-and-occupation-group-united-states-2015
#6
Taylor M Shockey, Sara E Luckhaupt, Matthew R Groenewold, Ming-Lun Lu
Repeated exposure to occupational ergonomic hazards, such as frequent exertion (repetitive bending or twisting) and frequent standing, can lead to injuries, most commonly musculoskeletal disorders (1). Work-related musculoskeletal disorders have been estimated to cost the United States approximately $2.6 billion in annual direct and indirect costs (2). A recent literature review provided evidence that prolonged standing at work also leads to adverse health outcomes, such as back pain, physical fatigue, and muscle pain (3)...
January 12, 2018: MMWR. Morbidity and Mortality Weekly Report
https://www.readbyqxmd.com/read/29324693/inhibiting-the-physiological-stress-effects-of-a-sustained-attention-task-on-shoulder-muscle-activity
#7
Fiona Wixted, Cliona O'Riordan, Leonard O'Sullivan
OBJECTIVE: The objective of this study was to investigate if a breathing technique could counteract the effects of hyperventilation due to a sustained attention task on shoulder muscle activity. BACKGROUND: The trend towards higher levels of automation in industry is increasing. Consequently, manufacturing operators often monitor automated process for long periods of their work shift. Prolonged monitoring work requires sustained attention, which is a cognitive process that humans are typically poor at and find stressful...
January 11, 2018: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29324458/ultrasound-imaging-and-guided-injection-for-the-lateral-and-posterior-hip
#8
Ke-Vin Chang, Wei-Ting Wu, Henry L Lew, Levent Özçakar
Ultrasound has emerged as one of the most utilized tools to diagnose musculoskeletal disorders and to assist in interventions. Traditionally, sonographic examination of the hip joint has been challenging because most of the major structures are deeply situated, thus requiring the use of curvilinear transducer for better penetrance. The posterior lateral hip is a frequent area for musculoskeletal pain and nerve entrapments. Common disorders include greater trochanteric pain syndrome, gluteus medius tendinopathy, piriformis syndrome, pudendal neuralgia and proximal hamstring tendinopathy...
January 11, 2018: American Journal of Physical Medicine & Rehabilitation
https://www.readbyqxmd.com/read/29320842/carpal-tunnel-syndrome-in-hiv-positive-patients-coinfected-with-hcv
#9
A Mastroianni, F Allegrini, S Nardi, D Donatucci, F Girelli, C Guidi
A wide range of rheumatic and peripheral nervous system disorders may develop in patients with HIV infection, leading to pain, sensory symptoms, and muscle weakness. Over the past three decades, the progress in management of HIV disease with anti-retroviral therapy (ART) has resulted in increased life expectancy for people living with HIV disease. With this new chronicity of the disease has a constellation of chronic musculoskeletal, orthopaedic and rheumatic manifestations has emerged, as potential complications of the disease itself and/or the results of ART treatment regimen and/or because of expected age-related symptoms/manifestations...
December 21, 2017: Reumatismo
https://www.readbyqxmd.com/read/29319178/glucose-enhances-aggrecan-expression-in-chondrocytes-via-the-pkc%C3%AE-p38-mir141-3p-signaling-pathway
#10
REVIEW
Tsung-Ju Wu, Yi-Chin Fong, Chih-Yang Lin, Yuan-Li Huang, Chih-Hsin Tang
Aggrecan is a high molecular weight proteoglycan that plays a critical role in cartilage structure and the function of joints, providing intervertebral disc and cartilage with the ability to resist compressive loads. Aggrecan degradation in articular cartilage is a significant event in early-stage osteoarthritis (OA). Currently, no effective treatment exists for OA other than pain relief. Dextrose (D-glucose) prolotherapy has shown promising activity in the treatment of different musculoskeletal disorders, including OA...
January 10, 2018: Journal of Cellular Physiology
https://www.readbyqxmd.com/read/29319149/pr%C3%A3-valence-et-d%C3%A3-terminants-des-troubles-musculosquelettiques-des-membres-sup%C3%A3-rieurs-chez-les-artisans-tunisiens
#11
Amira Omrane, Imene Kacem, Meriem Heni, Adnene Henchi, Sana Elmhami, Irtyah Merchaoui, Awatef Kraiem, Taoufik Khalfallah, Lamia Bouzgarrou
Musculoskeletal disorders (MSDs) of the upper limbs are a major occupational health problem. We report the results of a cross-sectional survey of 334 craftsmen from the governorate of Monastir in Tunisia. The objectives of this study were to assess the prevalence of MSDs among these workers and determine their risk factors. A pre-established questionnaire based on the Nordic MSD questionnaires, Karassik and the one developed by Malchaire in 2000 was used. In the 12 months prior to the survey, the prevalence of MSDs was 92...
January 2, 2018: Eastern Mediterranean Health Journal, la Revue de Santé de la Méditerranée Orientale
https://www.readbyqxmd.com/read/29318741/the-role-of-ergonomic-saddle-seats-and-magnification-loupes-in-the-prevention-of-musculoskeletal-disorders-a-systematic-review
#12
REVIEW
A Plessas, M Bernardes Delgado
OBJECTIVES: Musculoskeletal disorders affect a high percentage of dentists, dental hygienists and therapists. Static and awkward working postures are considered as major risk factors. Proper seat selection and use of magnification loupes are promoted for their ergonomic benefits. The aim of this review was to evaluate the existing empirical evidence on the effect of the above interventions on (i) correction of poor posture and (ii) reduction in musculoskeletal pain. METHODS: The review was conducted according to the PRISMA guidelines...
January 10, 2018: International Journal of Dental Hygiene
https://www.readbyqxmd.com/read/29317553/safety-profile-of-biosimilar-filgrastim-zarzio-zarxio-a-combined-analysis-of-phase-iii-studies
#13
Nadia Harbeck, Pere Gascón, Andriy Krendyukov, Nadja Hoebel, Sreekanth Gattu, Kimberly Blackwell
BACKGROUND: Evaluation of adverse events (AEs) in pivotal registration trials and ongoing postmarketing surveillance is important for all biologics, including biosimilars. A combined analysis of two pivotal registration studies was performed to strengthen evidence on safety for biosimilar filgrastim EP2006 in patients with breast cancer receiving myelosuppressive chemotherapy, a sensitive clinical setting to confirm biosimilarity of filgrastim. MATERIALS AND METHODS: Data were combined from two phase III studies of biosimilar filgrastim EP2006...
January 9, 2018: Oncologist
https://www.readbyqxmd.com/read/29317055/scapholunate-interosseous-ligament-dysfunction-as-a-source-of-elbow-pain-syndromes-possible-mechanisms-and-implications-for-hand-surgeons-and-therapists
#14
Cigdem Ayhan, Seval Tanrıkulu, Gursel Leblebicioglu
Elbow pain syndromes are common upper extremity musculoskeletal disorders, and they are usually associated with repetitive occupational exposure. Ligaments are often one of the sources of musculoskeletal disorders because of their mechanical and neurological properties. The wrist ligaments are some of the ligaments most vulnerable to occupational exposure. Since most occupational tasks require wrist extension for handling tools and loading, the scapholunate interosseous ligament (SLIL) bears greater strain during loading, which results in creep deformation and hysteresis...
January 2018: Medical Hypotheses
https://www.readbyqxmd.com/read/29311438/validity-and-responsiveness-of-the-work-functioning-impairment-scale-wfun-in-workers-with-pain-due-to-musculoskeletal-disorders
#15
Misako Makishima, Yoshihisa Fujino, Tatsuhiko Kubo, Hiroyuki Izumi, Masamichi Uehara, Ichiro Oyama, Shinya Matsuda
OBJECTIVE: To determine the convergent validity and responsiveness of the work functioning impairment scale (WFun) in workers with musculoskeletal disorder-related pain. METHODS: Participants were extracted from an internet user study and prospectively examined using the pain intensity numerical rating scale (pain-NRS), the work ability numerical rating scale (productivity-NRS), and the WFun at baseline, 2 weeks, 6 weeks, and 3 months. The convergent validity and responsiveness of the WFun were examined by multilevel regression analysis...
December 28, 2017: Journal of Occupational Health
https://www.readbyqxmd.com/read/29306961/prediction-models-to-identify-workers-at-risk-of-sick-leave-due-to-low-back-pain-in-the-dutch-construction-industry
#16
Lisa C Bosman, Lyan Dijkstra, Catelijne I Oling, Martijn W Heymans, Jos Wr Twisk, Corné Am Roelen
Objective The aim of this study was to develop a prediction model based on variables measured in occupational health checks to identify non-sick listed workers at risk of sick leave due to non-specific low-back pain (LBP). Methods This cohort study comprised manual (N=22 648) and non-manual (N=9735) construction workers who participated in occupational health checks between 2010 and 2013. Occupational health check variables were used as potential predictors and LBP sick leave was recorded during 1-year follow-up...
January 7, 2018: Scandinavian Journal of Work, Environment & Health
https://www.readbyqxmd.com/read/29302798/cone-beam-ct-of-the-musculoskeletal-system-clinical-applications
#17
REVIEW
Magdalena Posadzy, Julie Desimpel, Filip Vanhoenacker
OBJECTIVES: The aim of this pictorial review is to illustrate the use of CBCT in a broad spectrum of musculoskeletal disorders and to compare its diagnostic merit with other imaging modalities, such as conventional radiography (CR), Multidetector Computed Tomography (MDCT) and Magnetic Resonance Imaging. BACKGROUND: Cone Beam Computed Tomography (CBCT) has been widely used for dental imaging for over two decades. DISCUSSION: Current CBCT equipment allows use for imaging of various musculoskeletal applications...
January 4, 2018: Insights Into Imaging
https://www.readbyqxmd.com/read/29301760/trends-in-diagnosis-specific-work-disability-before-and-after-stroke-a-longitudinal-population-based-study-in-sweden
#18
Tea Lallukka, Jenni Ervasti, Erik Lundström, Ellenor Mittendorfer-Rutz, Emilie Friberg, Marianna Virtanen, Kristina Alexanderson
BACKGROUND: Although a stroke event often leads to work disability, diagnoses behind work disability before and after stroke are largely unknown. We examined the pre-event and postevent trends in diagnosis-specific work disability among patients of working age. METHODS AND RESULTS: We included all new nonfatal stroke events in 2006-2008 from population-based hospital registers in Sweden among women and men aged 25 to 60 years (n=12 972). Annual days of diagnosis-specific work disability were followed for 4 years before and after stroke...
January 4, 2018: Journal of the American Heart Association
https://www.readbyqxmd.com/read/29300819/labour-market-segregation-and-gender-differences-in-sickness-absence-trends-in-2005-2013-in-finland
#19
Taina Leinonen, Eira Viikari-Juntura, Kirsti Husgafvel-Pursiainen, Lauri J Virta, Mikko Laaksonen, Ilona Autti-Rämö, Svetlana Solovieva
Objectives: Women have higher sickness absence rate than men, but less is known of changes in this difference over time. We examined gender differences in sickness absence trends focusing on gender segregation in the labour market. Methods: We used large nationwide register data on Finnish wage earners aged 25-59 and generalized estimation equations based on repeated logistic regression to estimate the annual risk of sickness absence lasting at least 2 weeks. Results: Between 2005 and 2013, the age-adjusted proportion (%) of employees with all-cause sickness absence decreased from the initial levels of 10...
December 29, 2017: Annals of Work Exposures and Health
https://www.readbyqxmd.com/read/29298650/potential-application-of-centrifuges-to-protect-the-cns-in-space-and-on-earth
#20
Yoshiki Takamatsu, Gilbert Ho, Yuki Shimizu, Shuei Sugama, Takato Takenouchi, Masaaki Waragai, Jianshe Wei, Makoto Hashimoto
BACKGROUND: Centrifuges are the principal means of generating physiological hypergravity and have been used for many medical purposes, including the therapy of psychiatric diseases and evaluation of vestibular system in the pilots. In particular, modern centrifuges have evolved into mechanically sophisticated precision instruments compared to primitive ones in old times, indicating that centrifuges might possess great potential in modern medicine. Indeed, studies are in progress to apply centrifuges to musculoskeletal degenerative diseases, such as osteoporosis and sarcopenia...
December 29, 2017: Current Alzheimer Research
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