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nephrology kidney transplantation peritoneal dialysis renal

Janice Crespo-Salgado, V Matti Vehaskari, Tyrus Stewart, Michael Ferris, Qiang Zhang, Guangdi Wang, Eugene E Blanchard, Christopher M Taylor, Mahmoud Kallash, Larry A Greenbaum, Diego H Aviles
BACKGROUND: End-stage renal disease (ESRD) is associated with uremia and increased systemic inflammation. Alteration of the intestinal microbiota may facilitate translocation of endotoxins into the systemic circulation leading to inflammation. We hypothesized that children with ESRD have an altered intestinal microbiota and increased serum levels of bacterially derived uremic toxins. METHODS: Four groups of subjects were recruited: peritoneal dialysis (PD), hemodialysis (HD), post-kidney transplant and healthy controls...
2016: Microbiome
Ebun Ladipo Bamgboye
Chronic kidney disease (CKD) is a significant cause of morbidity and mortality in sub-Saharan Africa. This, along with other noncommunicable diseases like hypertension, diabetes, and heart diseases, poses a double burden on a region that is still struggling to cope with the scourge of communicable diseases like malaria, tuberculosis, HIV, and more recently Ebola. Causes of CKD in the region are predominantly glomerulonephritis and hypertension, although type 2 diabetes is also becoming a significant cause as is the retroviral disease...
August 10, 2016: Clinical Nephrology
Ramón García-Trabanino, Zulma Trujillo, Ana Verónica Colorado, Salvador Magaña Mercado, Carlos Atilio Henríquez
: El Salvador has the highest renal failure mortality rate in the Americas. Five healthcare providers offer renal replacement therapy (RRT) in the country. The national RRT prevalence has never been reported. AIMS: To determine the RRT prevalence in El Salvador and some basic characteristics. METHODS: The association of nephrology coordinated a nationwide cross-sectional survey during the third quarter of 2014. 31 renal centres participated in the survey, covering 99...
June 3, 2016: Nefrología: Publicación Oficial de la Sociedad Española Nefrologia
Aynur Gulcan, Erim Gulcan, Mustafa Keles, Esin Aktas
We aimed to investigate the frequency of oral yeast colonization (OYC) and the risk factors for patients who received continuous ambulatory peritoneal dialysis (CAPD) or hemodialysis (HD) or were renal transplant recipients (RTRs). The patients admitted to the Nephrology Clinic at Ataturk University Medical School from January through April 2013 were included in the study. A questionnaire about risk factors was filled out, and swab cultures were taken from the tongue surface of each participant. OYC was detected in 32...
June 2016: Comparative Immunology, Microbiology and Infectious Diseases
Niraj Desai, Mahboob Rahman
End-stage renal disease (ESRD) is associated with high rates of morbidity and mortality, and increased health care use. Optimal management of patients with ESRD requires close collaboration among primary care physicians, nephrology subspecialists, and other subspecialists. Critical issues for the family physician include helping patients transition from chronic kidney disease to ESRD, recognizing and managing common issues in patients receiving dialysis or after kidney transplantation, and understanding palliative care for patients with ESRD...
May 2016: FP Essentials
Ricardo Cintra Sesso, Antonio Alberto Lopes, Fernando Saldanha Thomé, Jocemir Ronaldo Lugon, Carmen Tzanno Martins
INTRODUCTION: National chronic dialysis data have had impact in the treatment planning. OBJECTIVE: To report data of the annual survey of the Brazilian Society of Nephrology about chronic kidney disease patients on dialysis in July 2014. METHODS: A survey based on data of dialysis units from the whole country. The data collection was performed by using a questionnaire filled out on-line by the dialysis units. RESULTS: Three hundred twelve (44%) of the dialysis units in the country answered the questionnaire...
March 2016: Jornal Brasileiro de Nefrologia: ʹorgão Oficial de Sociedades Brasileira e Latino-Americana de Nefrologia
Dong Chan Jin, Il Soo Ha, Nam Ho Kim, Seoung Woo Lee, Jong Soo Lee, Sung Ro Yoon, Byung Su Kim
The Korean Society of Nephrology (KSN) launched the official End-Stage Renal Disease (ESRD) Patient Registry in 1985 and the Internet online registry program was opened in 2001. The ESRD Registry Committee of KSN has collected data on dialysis therapy in Korea through the online registry program in the KSN Internet website. The increasing number of elderly people and diabetic patients in Korea has resulted in a very rapid increase in the number of ESRD patients. The total number of ESRD patients was 58,860 (hemodialysis [HD], 39,509; peritoneal dialysis [PD], 7309; and functioning kidney transplant [KT], 12,042)...
March 2012: Kidney Research and Clinical Practice
Dong Chan Jin, Jin Suk Han
The Korean Society of Nephrology (KSN) launched the official end-stage renal disease (ESRD) patient registry in 1985, and an Internet online registry program was opened in 2001 and revised in 2013. The ESRD Registry Committee of KSN has collected data on dialysis therapy in Korea through the online registry program in the KSN Internet website. The status of renal replacement therapy in Korea at the end of 2012 is described in the following. The total number of ESRD patients was 70,211 at the end of 2012, which included 48,531 hemodialysis (HD) patients, 7,552 peritoneal dialysis (PD) patients, and 14,128 functioning kidney transplant (KT) patients...
March 2014: Kidney Research and Clinical Practice
Brenda W Gillespie, Hal Morgenstern, Elizabeth Hedgeman, Anca Tilea, Natalie Scholz, Tempie Shearon, Nilka Rios Burrows, Vahakn B Shahinian, Jerry Yee, Laura Plantinga, Neil R Powe, William McClellan, Bruce Robinson, Desmond E Williams, Rajiv Saran
BACKGROUND: Longer nephrology care before end-stage renal disease (ESRD) has been linked with better outcomes. METHODS: We investigated whether longer pre-end-stage renal disease (ESRD) nephrology care was associated with lower mortality at both the patient and state levels among 443 761 incident ESRD patients identified in the USA between 2006 and 2010. RESULTS: Overall, 33% of new ESRD patients had received no prior nephrology care, while 28% had received care for >12 months...
December 2015: Clinical Kidney Journal
José Luis Teruel, Víctor Burguera Vion, Antonio Gomis Couto, Maite Rivera Gorrín, Milagros Fernández-Lucas, Nuria Rodríguez Mendiola, Carlos Quereda
INTRODUCTION: Incidence of use for various renal replacement therapies is well-known, but no data are available on conservative treatment use. OBJECTIVE: To assess the proportion of patients with chronic kidney failure receiving a conservative treatment. RESULTS: From July 1, 2013 to June 30, 2014, 232 patients with stage 5 CKD were seen in the Nephrology Department. After having received information on existing therapeutic options and having known the opinion of their treating physicians, 81 patients (35%) selected hemodialysis, 56 (24%) preferred peritoneal dialysis, 5 (2%) selected a preemptive transplant from a living donor, and in 90 (39%) a conservative treatment option was selected...
2015: Nefrología: Publicación Oficial de la Sociedad Española Nefrologia
Raymond Vanholder, Norbert Lameire, Lieven Annemans, Wim Van Biesen
The treatment of kidney diseases consumes a substantial amount of the health budget for a relatively small fraction of the overall population. If the nephrological community and society do not develop mechanisms to contain those costs, it will become impossible to continue assuring optimal outcomes and quality of life while treating all patients who need it. In this article, we describe several mechanisms to maintain sustainability of renal replacement therapy. These include (i) encouragement of transplantation after both living and deceased donation; (ii) stimulation of alternative dialysis strategies besides classical hospital haemodialysis, such as home haemodialysis, peritoneal dialysis or self-care and necessitating less reimbursement; (iii) promotion of educational activities guiding the patients towards therapies that are most suited for them; (iv) consideration of one or more of cost containment incentives such as bundling of reimbursement (if not affecting quality of the treatment), timely patient referral, green dialysis, start of dialysis based on clinical necessity rather than renal function parameters and/or prevention of CKD or its progression; (v) strategically planned adaptations to the expected growth of the ageing population in need of renal replacement; (vi) the necessity for support of research in the direction of helping as large as possible patient populations for acceptable costs; and (vii) the need for more patient-centred approaches...
August 2016: Nephrology, Dialysis, Transplantation
Mehmet Sukru Sever, Norbert Lameire, Wim Van Biesen, Raymond Vanholder
Natural and man-made mass disasters directly or indirectly affect huge populations, who need basic infrastructural help and support to survive. However, despite the potentially negative impact on survival chances, these health care issues are often neglected by the authorities. Treatment of both acute and chronic kidney diseases (CKDs) is especially problematic after disasters, because they almost always require complex technology and equipment, whereas specific drugs may be difficult to acquire for the treatment of the chronic kidney patients...
June 2015: Clinical Kidney Journal
Raúl Bohorques, Yanet Álvarez, Atilano Martínez, Yuliet Ballard, Sucel Pérez, Francisco Gutiérrez
INTRODUCTION: Peritoneal dialysis is a maintenance therapy option for patients with end-stage renal disease. Continuous ambulatory peritoneal dialysis in Cuba was introduced in December 2007, and automated peritoneal dialysis one year later. This paper presents the outcomes attained with this blood purification technique, enabling an assessment to decide on scaling up its use in Cuba. OBJECTIVE: Describe the clinical course of patients in the first five years of the Home Peritoneal Dialysis Program at Havana's Nephrology Institute...
April 2015: MEDICC Review
Mark R Marshall, Kevan R Polkinghorne, Peter G Kerr, John W M Agar, Carmel M Hawley, Stephen P McDonald
BACKGROUND: In most studies, home dialysis associates with greater survival than facility hemodialysis (HD). However, the relationship between mortality risk and modality can vary by era. We describe and compare changes in survival with facility HD, peritoneal dialysis, and home HD over a 15-year period using data from The Australia and New Zealand Dialysis and Transplant Registry (ANZDATA). STUDY DESIGN: An observational inception cohort study, using Cox proportional hazards and competing-risks regression...
September 2015: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
Hikmet Ismayilov, Shahin Qadimov, Kamil Muslumov, Khanbaba Huseynov, Fariz Babayev
OBJECTIVES: There is a saying that, to evaluate the level of medicine in a country, one should pay attention to its level of uronephrology service - specifically, the level of renal replacement therapy, hemodialysis, peritoneal dialysis, and transplant. With the increasing number of patients requiring renal replacement therapy, it is the utmost duty of modern medicine to structure and organize it. Since its establishment in 2000, MedServis Private Medical Centre has dedicated its main services to hemodialysis, renal replacement therapy, health care in other branches of medicine, follow-ups, and preparing patients for transplant...
April 2015: Experimental and Clinical Transplantation
Laura Sola, Raúl Plata-Cornejo, Juan Fernández-Cean
Uruguay and Bolivia are two countries that show heterogenicity of the Latin American region, including the national income, the expenditure on health and the services for renal care. In Bolivia, there is manpower shortage for renal care with only 5 nephrologists per million people (pmp) and the prevalence of patients on dialysis is only 200 pmp. This is much lower than the mean prevalence rate of renal replacement therapy for Latin America as a whole. Uruguay on the other hand has more dedicated renal resources with 50 nephrologists pmp, and renal replacement therapy is provided to ~ 1,000 dialysis patients pmp...
2015: Clinical Nephrology
Aziz El Matri
AIMS: This study was initiated under the auspices of the African Association of Nephrology to evaluate end-stage renal disease (ESRD) development by using data collected in 3 successive surveys performed during the last decade. MATERIALS AND METHODS: Questionnaires were sent in 2004, 2006, and 2012 to national renal societies and to leading nephrologists. Data were also collected from dialysis supply companies, personal communication, and by using research on Medline, Pubmed, etc...
2015: Clinical Nephrology
Ramón Alberto Tamayo-Isla, Mauro Cuba de la Cruz
INTRODUCTION: Calciphylaxis is a rare medical condition that is usually diagnosed in patients suffering from end-stage renal disease who are already receiving renal replacement therapy and in those post-transplantation. The pathogenesis still remains to be fully elucidated; hence, the treatment is not uniform. The prognosis is generally poor. The ulcerative stage exhibits a worse prognosis than the nonulcerative one. Calciphylaxis presenting in terminal kidney disease prior to dialytic treatment has only rarely been reported...
2015: International Journal of Nephrology and Renovascular Disease
Alexander J Hamilton, Rishi Pruthi, Heather Maxwell, Anna Casula, Fiona Braddon, Carol Inward, Malcolm Lewis, Catherine O'Brien, Jelena Stojanovic, Yincent Tse, Manish D Sinha
BACKGROUND: The Paediatric Registry analyses renal replacement therapy (RRT) data in children. All 13 UK paediatric nephrology centres submit electronic data. AIMS: To provide centre specific data and to determine adherence to relevant audit standards. METHODS: Data analysis to calculate summary statistics and achievement of an audit standard. RESULTS: The median height z-score for children on dialysis was -2.0 and for children with a functioning transplant -1...
2015: Nephron
Motoshi Hattori, Mayumi Sako, Tetsuji Kaneko, Akira Ashida, Akira Matsunaga, Tohru Igarashi, Noritomo Itami, Toshiyuki Ohta, Yoshimitsu Gotoh, Kenichi Satomura, Masataka Honda, Takashi Igarashi
BACKGROUND: End-stage renal disease (ESRD) in children is considered a rare, but serious condition. Epidemiological and demographic information on pediatric ESRD patients around the world is important to better understand this disease and to improve patient care. The Japanese Society for Pediatric Nephrology (JSPN) reported epidemiological and demographic data in 1998. Since then, however, there has been no nationwide survey on Japanese children with ESRD. METHODS: The JSPN conducted a cross-sectional nationwide survey in 2012 to update information on the incidence, primary renal disease, initial treatment modalities, and survival in pediatric Japanese patients with ESRD aged less than 20 years during the period 2006-2011...
October 2015: Clinical and Experimental Nephrology
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