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vestibulodynia

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https://www.readbyqxmd.com/read/28979166/provoked-vestibulodynia-current-perspectives
#1
REVIEW
Helen Henzell, Karen Berzins, Jennifer P Langford
Provoked vestibulodynia (PVD) refers to vulvar pain of at least 3 months duration, localized to the vestibule, provoked by touch and sexual activity and occurring in the absence of a clear identifiable cause. The clinical spectrum ranges from mild with distressing discomfort through to severe and disabling pain. Current understanding is that PVD is one of many chronic pain conditions characterized by sensitization of peripheral and central nociceptive pathways, with pain arising due to dysfunctional neuronal activity in the absence of painful stimuli...
2017: International Journal of Women's Health
https://www.readbyqxmd.com/read/28970071/low-level-laser-therapy-for-the-treatment-of-provoked-vestibulodynia-a-randomized-placebo-controlled-pilot-trial
#2
Ahinoam Lev-Sagie, Asia Kopitman, Amnon Brzezinski
BACKGROUND: Low-level laser therapy (LLLT) is an emerging medical technology in which non-thermal laser irradiation is applied to treat pain. Because LLLT has been found effective in treating various pain syndromes without known side effects, we conducted a study evaluating the effect of LLLT on provoked vestibulodynia (PVD), a complex sexual pain disorder characterized by pain confined to the vulvar vestibule in response to contact or pressure. AIM: To investigate the effectiveness of LLLT for PVD in a randomized, placebo-controlled, double-blinded trial...
September 29, 2017: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/28964711/a-comparison-of-approach-and-avoidance-sexual-goals-in-couples-with-vulvodynia-and-community-controls
#3
Justin P Dubé, Sophie Bergeron, Amy Muise, Emily A Impett, Natalie O Rosen
BACKGROUND: Provoked vestibulodynia (PVD) is a prevalent form of vulvodynia that interferes with the sexual and relational functioning of affected couples. Approach and avoidance sexual goals are associated with the sexual and relationship well-being of women with PVD and their partners. However, whether sexual goals differ in couples coping with PVD compared with community couples is unknown. AIMS: To compare the approach and avoidance sexual goals of women with PVD and their partners with a control sample of community women and their partners to build on an established motivational model and to compare the sexual goals of women with PVD with those of their partners...
September 27, 2017: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/28764581/skin-diseases-of-the-vulva-inflammatory-erosive-ulcerating-and-apocrine-gland-diseases-zinc-and-vitamin-deficiency-vulvodynia-and-vestibulodynia
#4
Freja Lærke Sand, Simon Francis Thomsen
Chronic, inflammatory and ulcerating mucocutaneous diseases that can affect the vulvar area are reviewed: lichen sclerosus, lichen planus, plasma cell vulvitis, complex aphthosis, Behcet's disease, pyoderma gangrenosum, metastatic Crohn's disease, dyskeratotic skin diseases (Hailey-Hailey disease and Darier's disease), autoimmune bullous diseases (mucous membrane pemphigoid and pemphigus vulgaris) and hidradenitis suppurativa. Also, vulvodynia and vestibulodynia, zinc and vitamin B deficiency are described.
August 1, 2017: Journal of Obstetrics and Gynaecology: the Journal of the Institute of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28364981/heightened-pelvic-floor-muscle-tone-and-altered-contractility-in-women-with-provoked-vestibulodynia
#5
COMPARATIVE STUDY
Mélanie Morin, Yitzchak M Binik, Daniel Bourbonnais, Samir Khalifé, Stéphane Ouellet, Sophie Bergeron
BACKGROUND: Pelvic floor muscle (PFM) dysfunctions are reported to be involved in provoked vestibulodynia (PVD). Although heightened PFM tone has been suggested, the relative contribution of active and passive components of tone remains misunderstood. Likewise, alterations in PFM contractility have been scarcely studied. AIMS: To compare PFM tone, including the relative contribution of its active and passive components, and muscular contractility in women with PVD and asymptomatic controls...
April 2017: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/28363763/systematic-review-of-the-effectiveness-of-physical-therapy-modalities-in-women-with-provoked-vestibulodynia
#6
REVIEW
Mélanie Morin, Marie-Soleil Carroll, Sophie Bergeron
INTRODUCTION: Pelvic floor muscle physical therapy is recommended in clinical guidelines for women with provoked vestibulodynia (PVD). Including isolated or combined treatment modalities, physical therapy is viewed as an effective first-line intervention, yet no systematic review concerning the effectiveness of physical therapy has been conducted. AIM: To systematically appraise the current literature on the effectiveness of physical therapy modalities for decreasing pain during intercourse and improving sexual function in women with PVD...
March 28, 2017: Sexual Medicine Reviews
https://www.readbyqxmd.com/read/28343555/provoked-vestibulodynia-diagnosis-self-reported-pain-and-presentation-during-gynaecological-examinations
#7
Emma E Dargie, Susan M Chamberlain, Caroline F Pukall
OBJECTIVE: To explore factors associated with the diagnosis of provoked vestibulodynia (PVD) through (1) self-reported pain characteristics and (2) Friedrich's criteria (vestibular pain during sexual activity/gynaecological examination). We also identified cases in which incorrect diagnoses were assigned and explored group differences in gynaecological examination presentation and associations with self-reported pain. METHODS: Data were extracted from nine studies conducted in our research laboratory...
March 2017: Journal of Obstetrics and Gynaecology Canada: JOGC, Journal D'obstétrique et Gynécologie du Canada: JOGC
https://www.readbyqxmd.com/read/28343553/alpha-lipoic-acid-plus-omega-3-fatty-acids-for-vestibulodynia-associated-with-painful-bladder-syndrome
#8
RANDOMIZED CONTROLLED TRIAL
Filippo Murina, Alessandra Graziottin, Raffaele Felice, Dania Gambini
OBJECTIVE: This study assessed the effectiveness of alpha lipoic acid (ALA) plus omega-3 polyunsaturated fatty acids (n-3 PUFAs) in combination with amitriptyline therapy in patients with vestibulodynia/painful bladder syndrome (VBD/PBS). METHODS: Women with VBD/PBS were randomly assigned to receive amitriptyline or amitriptyline plus a commercially available preparation (ALAnerv Age; Alfa Wassermann, Bologna, Italy) containing, in 2 capsules, ALA 600 mg plus docosahexaenoic acid 250 mg and eicosapentaenoic acid 16...
March 2017: Journal of Obstetrics and Gynaecology Canada: JOGC, Journal D'obstétrique et Gynécologie du Canada: JOGC
https://www.readbyqxmd.com/read/28342741/treatment-of-secondary-vestibulodynia-with%C3%A2-conjugated-estrogen-cream-a-pilot-double-blind-randomized-placebo-controlled-trial
#9
Eve-Lyne Langlais, Jessica Lefebvre, Sarah Maheux-Lacroix, Emmanuel Bujold, Michel Fortier, Céline Bouchard
OBJECTIVE: To assess the efficacy of conjugated equine estrogen cream in reducing dyspareunia associated with secondary provoked vestibulodynia. METHODS: We conducted a randomized, double-blind, placebo-controlled trial that included women with secondary provoked vestibulodynia. Participants were randomly allocated to daily application of conjugated equine estrogen cream on the vulvar vestibule (estrogen group) or daily application of a similar placebo cream (placebo group)...
June 2017: Journal of Obstetrics and Gynaecology Canada: JOGC, Journal D'obstétrique et Gynécologie du Canada: JOGC
https://www.readbyqxmd.com/read/28325536/self-reported-neuropathic-pain-characteristics-of-women-with-provoked-vulvar-pain-a-preliminary-investigation
#10
Emma Dargie, Ian Gilron, Caroline F Pukall
BACKGROUND: Provoked vestibulodynia (PVD) is a common chronic genital pain condition affecting approximately 12% of premenopausal women. Although parallels have been drawn between PVD and neuropathic pain (NP), no studies have examined self-reported NP characteristics in PVD. AIM: To explore pain symptoms that resemble NP reported by those with PVD and compare responses with those with an established NP condition. METHODS: Women with provoked vulvar pain (PVP; n = 65) completed online questionnaires designed to assess characteristics of NP...
April 2017: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/28302387/efficacy-of-transcranial-direct-current-stimulation-in-women-with-provoked-vestibulodynia
#11
RANDOMIZED CONTROLLED TRIAL
Annie Morin, Guillaume Léonard, Véronique Gougeon, Marie-Pierre Cyr, Guy Waddell, Yves-André Bureau, Isabelle Girard, Mélanie Morin
BACKGROUND: Provoked vestibulodynia is a highly prevalent condition characterized by acute recurrent pain located at the vaginal entrance in response to pressure application or attempted vaginal penetration. Despite a wide variety of treatments offered to women with provoked vestibulodynia, a high proportion of women are refractory to conventional treatment. Transcranial direct-current stimulation is a noninvasive brain stimulation technique that has been shown effective for improving various chronic pain conditions...
June 2017: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28238679/how-does-paying-attention-improve-sexual-functioning-in-women-a%C3%A2-review-of-mechanisms
#12
REVIEW
Nikita Arora, Lori A Brotto
INTRODUCTION: Female sexual dysfunction (FSD), consisting of a constellation of distressing sexual symptoms, is highly prevalent worldwide. Given the central role played by psychological factors in the development of FSD, psychologically and in particular mindfulness-based interventions have arisen as potential treatment options for women. Although mindfulness-based interventions have been evaluated in samples of women with gynecologic cancer; a history of sexual abuse; multiple sclerosis; and spinal cord injury; and provoked vestibulodynia, the mechanisms by which mindfulness leads to improvements in sexual functioning are largely unstudied...
February 23, 2017: Sexual Medicine Reviews
https://www.readbyqxmd.com/read/28178074/a-common-pronociceptive-pain-modulation-profile-typifying-subgroups-of-chronic-pelvic-pain-syndromes-is-interrelated-with-enhanced-clinical-pain
#13
Keren Grinberg, Michal Granot, Lior Lowenstein, Liora Abramov, Irit Weissman-Fogel
Provoked vestibulodynia (PVD) and painful bladder syndrome (PBS), subgroups of chronic pelvic pain syndromes (CPPS), are considered to share common biophysiological peripheral mechanisms. In addition, indications of a pronociceptive pain profile coexisting with psychological vulnerability suggest common dysfunctional pain processing and pain modulation in these 2 subgroups of CPPS. We therefore aimed at comparing the pain profile and psychological traits of patients with PVD and PBS to see whether the pain profile contributes to intersubject variability of clinical pain symptoms...
June 2017: Pain
https://www.readbyqxmd.com/read/28118257/provoked-vestibulodynia-a-comparative-examination-of-mental-health-sleep-sexual-functioning-and-relationship-adjustment
#14
Emma Dargie, Ian Gilron, Caroline Pukall
OBJECTIVES: Provoked vestibulodynia (PVD) is an idiopathic vulvar pain condition characterized by burning pain at the vaginal opening in response to contact or pressure. Previous research has established some of the psychosocial difficulties experienced by these patients, but direct comparisons with other pain conditions are needed. The purpose of this study was to compare women with PVD to those with post-herpetic neuralgia and pain-free control participants. METHODS: Participants were invited to complete an anonymous online survey consisting of sociodemographic questions and a range of validated measures...
January 21, 2017: Clinical Journal of Pain
https://www.readbyqxmd.com/read/28062309/a-local-inflammatory-renin-angiotensin-system-drives-sensory-axon-sprouting-in-provoked-vestibulodynia
#15
Zhaohui Liao, Anuradha Chakrabarty, Ying Mu, Aritra Bhattacherjee, Martha Goestch, Catherine M Leclair, Peter G Smith
Vestibulodynia is a form of provoked vulvodynia characterized by profound tenderness, hyperinnervation, and frequently inflammation within well-defined areas of the human vestibule. Previous experiments in animal models show that inflammatory hypersensitivity and hyperinnervation occur in concert with establishment of a local renin-angiotensin system (RAS). Moreover, mechanical hypersensitivity and sensory axon sprouting are prevented by blocking effects of angiotensin II on angiotensin II receptor type 2 (AT2) receptors...
January 3, 2017: Journal of Pain: Official Journal of the American Pain Society
https://www.readbyqxmd.com/read/28028667/interpersonal-goals-and-well-being-in-couples-coping-with-genito-pelvic-pain
#16
Natalie O Rosen, Marieke Dewitte, Kathleen Merwin, Sophie Bergeron
In the context of genito-pelvic pain, consideration of interpersonal goals is particularly relevant given that couples' distress is often predicated upon the relational setting. However, relationship goals have not been examined in this population. We investigated (1) the associations between relationship goals and women's pain during intercourse as well as the sexual, relational, and psychological well-being of women with provoked vestibulodynia (PVD) and their partners and (2) the moderating role of sexual goals in these associations...
December 27, 2016: Archives of Sexual Behavior
https://www.readbyqxmd.com/read/27984345/vulvodynia-what-we-know-and-where-we-should-be-going
#17
REVIEW
Logan M Havemann, David R Cool, Pascal Gagneux, Michael P Markey, Jerome L Yaklic, Rose A Maxwell, Ashvin Iyer, Steven R Lindheim
OBJECTIVE: The aim of the study was to review the current nomenclature and literature examining microbiome cytokine, genomic, proteomic, and glycomic molecular biomarkers in identifying markers related to the understanding of the pathophysiology and diagnosis of vulvodynia (VVD). MATERIALS AND METHODS: Computerized searches of MEDLINE and PubMed were conducted focused on terminology, classification, and "omics" variations of VVD. Specific MESH terms used were VVD, vestibulodynia, metagenomics, vaginal fungi, cytokines, gene, protein, inflammation, glycomic, proteomic, secretomic, and genomic from 2001 to 2016...
April 2017: Journal of Lower Genital Tract Disease
https://www.readbyqxmd.com/read/27892829/understanding-the-sexual-satisfaction-of-women-with-provoked-vestibulodynia-and-their-partners-comparison-with-matched-controls
#18
Natalie O Rosen, Pablo Santos-Iglesias, E Sandra Byers
Provoked vestibulodynia (PVD)-a recurrent, localized vulvar pain-interferes with couples' sexual relationships as evidenced by lower sexual satisfaction compared to controls. Little is known about what components of sexual satisfaction contribute to this lower satisfaction. Using the Interpersonal Exchange Model of Sexual Satisfaction (IEMSS), we compared the sexual exchanges (sexual rewards and costs, relative sexual rewards and costs, balance of sexual rewards and costs, balance of relative sexual rewards and costs, equality of sexual rewards and costs) and sexual satisfaction of 50 women with PVD and their male partners to 50 matched-control couples...
November 28, 2016: Journal of Sex & Marital Therapy
https://www.readbyqxmd.com/read/27872003/primary-and-secondary-provoked-vestibulodynia-a-review-of-overlapping-and-distinct-factors
#19
REVIEW
Caroline F Pukall
INTRODUCTION: A common subtype of vulvodynia is provoked vestibulodynia (PVD), characterized by severe pain upon contact to the vaginal entrance. Some researchers have further delineated the PVD group based on pain onset (primary vs secondary PVD, referred to as PVD1 and PVD2, respectively). AIM: This study aims to review available evidence regarding sociodemographic variables, pain characteristics, medical history and examination findings, quantitative sensory testing, genetic markers, psychosocial/sexual/relationship function, treatment outcome, and brain imaging in women with PVD1 and PVD2...
January 2016: Sexual Medicine Reviews
https://www.readbyqxmd.com/read/27864031/fractional-co2-laser-treatment-of-the-vestibule-for-patients-with-vestibulodynia-and-genitourinary-syndrome-of-menopause-a-pilot-study
#20
Filippo Murina, Mickey Karram, Stefano Salvatore, Raffaele Felice
INTRODUCTION: Chronic vulvar pain and burning remains one of the most perplexing problems faced by practicing gynecologists. AIM: To evaluate the effectiveness and safety of the application of micro-ablative fractional CO2 laser to the vulvar vestibule in the management of patients with vulvar pain from vestibulodynia or genitourinary syndrome of menopause. METHODS: Patients (N = 70) underwent fractional micro-ablative CO2 laser treatment for vestibular pain plus vestibulodynia (n = 37) or genitourinary syndrome of menopause (n = 33)...
December 2016: Journal of Sexual Medicine
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