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https://www.readbyqxmd.com/read/28427490/is-the-mortality-trend-of-ischemic-heart-disease-by-the-gbd2013-study-in-china-real
#1
Xia Wan, Gong Huan Yang
To determine the reason for the different mortality trends of ischemic heart disease (IHD) for China between Global Burden of Disease (GBD) 2010 and GBD2013, and to improve garbage code (GC) redistribution. All data were obtained from the disease surveillance points system, and two proportions for assigning chronic pulmonary heart disease (PHD) as GC to IHD were from GBD2010 and GBD2013, which were different for years before 2004. By using the GBD2013 approach, the age-standard mortality rate (ASMR) increased by 100...
March 2017: Biomedical and Environmental Sciences: BES
https://www.readbyqxmd.com/read/28426662/plos-neglected-tropical-diseases-ten-years-of-progress-in-neglected-tropical-disease-control-and-elimination-%C3%A2-more-or-less
#2
EDITORIAL
Peter Hotez, Serap Aksoy
This year PLOS Neglected Tropical Diseases (PLOS NTDs) celebrates its tenth anniversary following the publication of the first issue in 2007 [1]. When PLOS NTDs was founded, the framework of the neglected tropical diseases (NTDs) as an alternative to "other diseases" (as they were then referred to in the Millennium Development Goals) was just getting started-especially for Africa [2, 3]. In the decade since, PLOS NTDs has overseen enormous successes in NTD control and elimination. Here, we want to briefly review the ten year progress made towards the control or elimination of the diseases now identified by the WHO as NTDs...
April 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28399833/a-comparison-of-dalys-for-periodontal-disease-in-china-between-1990-and-2013-insights-from-the-2013-global-burden-of-disease-study
#3
Qi Zhang, Zhixin Li, Chunxiao Wang, Yunning Liu, Yang Yang, Scottie Bussell, Maigeng Zhou, Linhong Wang
BACKGROUND: China has undergone a rapid demographic and epidemiological transition with fast ecomonic development since the 1980s. Oral health is becoming a major public health problem as the prevalence of non-communicable diseases has greatly increased. Periodontal disease (PD) and caries are among the most prevalent oral diseases. PD accounts for the majority of tooth loss and increases with age. China's third national epidemiological investigation on oral diseases (2005) revealed that periodontitis affected >50% of the adult population...
April 11, 2017: BMC Oral Health
https://www.readbyqxmd.com/read/28390697/smoking-prevalence-and-attributable-disease-burden-in-195-countries-and-territories-1990-2015-a-systematic-analysis-from-the-global-burden-of-disease-study-2015
#4
(no author information available yet)
BACKGROUND: The scale-up of tobacco control, especially after the adoption of the Framework Convention for Tobacco Control, is a major public health success story. Nonetheless, smoking remains a leading risk for early death and disability worldwide, and therefore continues to require sustained political commitment. The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) offers a robust platform through which global, regional, and national progress toward achieving smoking-related targets can be assessed...
April 5, 2017: Lancet
https://www.readbyqxmd.com/read/28369739/the-global-burden-of-melanoma-results-from-global-burden-of-disease-study-2015
#5
C Karimkhani, A C Green, T Nijsten, M A Weinstock, R P Dellavalle, M Naghavi, C Fitzmaurice
BACKGROUND: Despite recent improvements in prevention, diagnosis, and treatment, vast differences in melanoma burden still exist between populations. Comparative data can highlight these differences and lead to focused efforts to reduce the burden of melanoma. OBJECTIVES: To assess global, regional, and national melanoma incidence, mortality, and disability-adjusted life year (DALY) estimates from the Global Burden of Disease 2015 study. METHODS: Vital registration system and cancer registry data were used for melanoma mortality modeling...
March 30, 2017: British Journal of Dermatology
https://www.readbyqxmd.com/read/28363304/international-disease-burden-of-hand-burns-perspective-from-the-global-health-arena
#6
REVIEW
Daniel S Corlew, K A Kelly McQueen
Measuring the extent and impact of a health problem is key to being able to address it appropriately. This review uses available information within the framework of the Global Burden of Disease studies to estimate the disease burden due to burn injuries of the hands. The GBD indicates that since 1990 there has been an approximately 30% decrease in the disease burden related to burn injuries. The GBD methods have not been applied specifically to hand burns, but from available data, it is estimated that about 18 million people in the world suffer from sequelae of burns to the hands...
May 2017: Hand Clinics
https://www.readbyqxmd.com/read/28351285/heparanase-overexpression-down-regulates-syndecan-1-expression-in-a-gallbladder-carcinoma-cell-line
#7
Hao Jin, Shaobo Zhou, Song Yang, Hai-Ming Cao
Objective To discuss the relevance of heparanase and syndecan-1 and regulation of the heparanase-syndecan1 axis in the invasiveness of gallbladder carcinoma cells. Methods 1. Generation of a gallbladder cancer cell line overexpressing a heparanase (GBD-SD) transgene. 2. Western blot analysis of syndecan-1 levels of GBD-SD and control gallbladder carcinoma (GBC-SD) cells. 3. RT-PCR analysis of syndecan-1 mRNA levels of GBD-SD and GBC-SD. 4. Evaluation of invasion and migration of GBD-SD and GBC-SD cells. Results 1...
January 1, 2017: Journal of International Medical Research
https://www.readbyqxmd.com/read/28340488/national-and-sub-national-age-sex-specific-and-cause-specific-mortality-and-disability-adjusted-life-years-dalys-attributable-to-household-air-pollution-from-solid-cookfuel-use-hap-in-iran-1990-2013
#8
Mehrnoosh Abtahi, Ali Koolivand, Sina Dobaradaran, Kamyar Yaghmaeian, Anoushiravan Mohseni-Bandpei, Shokooh Sadat Khaloo, Sahand Jorfi, Reza Saeedi
National and sub-national mortality, years of life lost due to premature mortality (YLLs), years lived with disability (YLDs) and disability-adjusted life years (DALYs) for household air pollution from solid cookfuel use (HAP) in Iran, 1990-2013 were estimated based on the Global Burden of Disease Study 2013 (GBD 2013). The burden of disease attributable to HAP was quantified by the comparative risk assessment method using four inputs: (1) exposure to HAP, (2) the theoretical minimum risk exposure level (TMREL), (3) exposure-response relationships of related causes (4) disease burden of related causes...
March 21, 2017: Environmental Research
https://www.readbyqxmd.com/read/28331842/estimation-of-burden-of-ischemic-heart-diseases-in-isfahan-iran-2014-using-incompleteness-and-misclassification-adjustment-models
#9
Mehran Shams-Beyranvand, Farshad Farzadfar, Shohreh Naderimagham, Maryam Tirani, Mohammad Reza Maracy
BACKGROUND: Over the past decade, cardiovascular diseases (CVDs) have been the leading cause of death in the world. Ischemic heart diseases (IHDs) are the main form of CVDs and are the most important single cause of death around the world. This study aimed to estimate the burden of IHDs in the city of Isfahan by calculating disability-adjusted life years (DALYs). METHODS: This population-based study was conducted on the population living in the city of Isfahan in 2014...
2017: Journal of Diabetes and Metabolic Disorders
https://www.readbyqxmd.com/read/28322530/-stima-dei-decessi-per-tumori-attribuibili-a-fattori-di-rischio-comportamentali-in-italia-nel-2013
#10
Francesca Battisti, Giulia Carreras, Tommaso Grassi, Elisabetta Chellini, Giuseppe Gorini
"Non-communicable diseases cause more than 80% of deaths in europe and, among these, 20% are caused by cancer. Modifiable lifestyle factors considered in the italian national programme "Guadagnare salute" (Gaining health), such as tobacco smoking, unhealthy diet, physical inactivity, overweight, and excessive alcohol use, are amongst the major causes of cancer deaths. The aims of this study was to estimate the number of deaths attributable to lifestyle factors for italy and for italian regions in 2013 and to describe its variation in relation to the regional prevalence of risk factors exposure...
January 2017: Epidemiologia e Prevenzione
https://www.readbyqxmd.com/read/28295702/effect-of-steroid-hormones-on-the-innate-immune-response-induced-by-staphylococcus-aureus-in-the-goat-mammary-gland
#11
K Kuwahara, Y Yoshimura, N Isobe
The objective of this study was to compare the dynamics of innate immune components after intramammary infusion of Staphylococcus aureus (SA) under conditions of high oestrogen and high progesterone in goats. In one group ("E-group"), controlled internal drug release (CIDR) devices were inserted intravaginally from days -11 to -4. Prostaglandin F2α was administered immediately after removal of the CIDR device at day -3, and then oestradiol benzoate (E) was injected intramuscularly once a day from days -2 to 3...
March 12, 2017: Reproduction in Domestic Animals, Zuchthygiene
https://www.readbyqxmd.com/read/28295095/first-experimental-demonstration-of-faster-than-nyquist-pdm-16qam-transmission-over-standard-single-mode-fiber
#12
Zhuopeng Xiao, B Li, Songnian Fu, L Deng, M Tang, Deming Liu
We demonstrate faster-than-Nyquist (FTN) transmission with a novel mitigation scheme of intercarrier interference. To the best of our knowledge, it is the first experimental demonstration of FTN PDM-16QAM transmission over standard single mode fiber (SSMF). Due to the use of maximum likelihood sequence detection and multi-input multi-output processing for severely overlapped Nyquist-PDM-16QAM carriers, 5.4-dB optical signal-to-noise ratio improvement is experimentally observed under the scenario of 2×16-GBd PDM-16QAM back-to-back transmission with a carrier spacing of 15 GHz...
March 15, 2017: Optics Letters
https://www.readbyqxmd.com/read/28291535/the-health-burden-and-economic-costs-averted-by-ambient-pm2-5-pollution-reductions-in-nagpur-india
#13
Tunde O Etchie, Saravanadevi Sivanesan, Gregory O Adewuyi, Kannan Krishnamurthi, Padma S Rao, Ayotunde T Etchie, Ajay Pillarisetti, Narendra K Arora, Kirk R Smith
National estimates of the health and economic burdens of exposure to ambient fine particulate matter (PM2.5) in India reveal substantial impacts. This information, often lacking at the local level, can justify and drive mitigation interventions. Here, we assess the health and economic gains resulting from attainment of WHO guidelines for PM2.5 concentrations - including interim target 2 (IT-2), interim target 3 (IT-3), and the WHO air quality guideline (AQG) - in Nagpur district to inform policy decision making for mitigation...
March 10, 2017: Environment International
https://www.readbyqxmd.com/read/28277978/targeted-dna-demethylation-in-human-cells-by-fusion-of-a-plant-5-methylcytosine-dna-glycosylase-to-a-sequence-specific-dna-binding-domain
#14
Jara Teresa Parrilla-Doblas, Rafael R Ariza, Teresa Roldán-Arjona
DNA methylation is a crucial epigenetic mark associated to gene silencing, and its targeted removal is a major goal of epigenetic editing. In animal cells, DNA demethylation involves iterative 5mC oxidation by TET enzymes followed by replication-dependent dilution and/or replication-independent DNA repair of its oxidized derivatives. In contrast, plants use specific DNA glycosylases that directly excise 5mC and initiate its substitution for unmethylated C in a base excision repair process. In this work, we have fused the catalytic domain of Arabidopsis ROS1 5mC DNA glycosylase (ROS1_CD) to the DNA binding domain of yeast GAL4 (GBD)...
April 3, 2017: Epigenetics: Official Journal of the DNA Methylation Society
https://www.readbyqxmd.com/read/28274383/cancer-research-priorities-and-gaps-in-iran-the-influence-of-cancer-burden-on-cancer-research-outputs-between-1997-and-2014
#15
A Majidi, H Salimzadeh, O Beiki, F Delavari, S Majidi, A Delavari, R Malekzadeh
OBJECTIVES: As a developing country, Iran is experiencing the increasing burden of cancers, which are currently the third leading cause of mortality in Iran. This study aims to demonstrate that cancer research in Iran concentrates on the cancer research priorities based on the global burden of disease (GBD) reports. STUDY DESIGN: Descriptive evaluation of all cancers disability-adjusted life years (DALYs) was performed using GBD data. Also a comprehensive search was conducted using cancer-associated keywords to obtain all cancer-related publications from Iran, indexed in Web of Science...
March 2017: Public Health
https://www.readbyqxmd.com/read/28272497/the-nucleus-accumbens-and-ketamine-treatment-in-major-depressive-disorder
#16
Chadi G Abdallah, Andrea Jackowski, Ramiro Salas, Swapnil Gupta, João R Sato, Xiangling Mao, Jeremy D Coplan, Dikoma C Shungu, Sanjay J Mathew
Animal models of depression repeatedly showed stress-induced nucleus accumbens (NAc) hypertrophy. Recently, ketamine was found to normalize this stress-induced NAc structural growth. Here, we investigated NAc structural abnormalities in major depressive disorder (MDD) in two cohorts. Cohort A included a cross-sectional sample of 34 MDD and 26 healthy control (HC) subjects, with high-resolution magnetic resonance imaging (MRI) to estimate NAc volumes. Proton MR spectroscopy ((1)H MRS) was used to divide MDD subjects into two subgroups: glutamate-based depression (GBD) and non-GBD...
March 29, 2017: Neuropsychopharmacology: Official Publication of the American College of Neuropsychopharmacology
https://www.readbyqxmd.com/read/28260333/-subnational-analysis-of-probability-of-premature-mortality-caused-by-four-main-non-communicable-diseases-in-china-during-1990-2015-and-health-china-2030-reduction-target
#17
X Y Zeng, Y C Li, S W Liu, L J Wang, Y N Liu, J M Liu, M G Zhou
Objective: To investigate the current status, temporal trend and achieving Health China 2030 reduction target of probability of premature mortality caused by four main non-communicable diseases (NCDs) including cardiovascular and cerebrovascular diseases, tumour, diabetes, and chronic respiratory disease in China both at national and provincial level during 1990 to 2015. Methods: Using the results of Global Burden of Disease study 2015 (GBD 2015), according to the method of calculating premature mortality probability recommended by WHO, the current status and temporal trend by different gender from 1990 to 2015 were calculated, analyzed, and compared...
March 6, 2017: Zhonghua Yu Fang Yi Xue za Zhi [Chinese Journal of Preventive Medicine]
https://www.readbyqxmd.com/read/28259594/eus-guided-gallbladder-drainage-in-patients-with-acute-cholecystitis-and-high-surgical-risk-using-an-electrocautery-enhanced-lumen-apposing-metal-stent-device
#18
Markus Dollhopf, Alberto Larghi, Uwe Will, Mihai Rimbaş, Andrea Anderloni, Andres Sanchez-Yague, Anthony Yuen Bun Teoh, Rastislav Kunda
BACKGROUND AND AIMS: In high-risk surgical patients, the treatment of choice of acute cholecystitis is percutaneous transhepatic gallbladder drainage (PTGBD). Recently, a novel endoscopic device containing a lumen-apposing metal stent with an electrocautery (ECE-LAMS) on the tip has been developed. METHODS: High-risk surgical patients with acute cholecystitis who underwent EUS-guided gallbladder drainage (EUS-GBD) with the novel device were retrospectively retrieved from 7 tertiary-care referral centers...
March 1, 2017: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/28241659/on-the-bandwidth-dependent-performance-of-split-transmitter-receiver-optical-fiber-nonlinearity-compensation
#19
Domaniç Lavery, Robert Maher, Gabriele Liga, Daniel Semrau, Lidia Galdino, Polina Bayvel
The Gaussian noise model is used to estimate the performance of three digital nonlinearity compensation (NLC) algorithms in C-band, long-haul, optical fiber transmission, when the span length and NLC bandwidth are independently varied. The algorithms are receiver-side digital backpropagation (DBP), transmitter-side DBP (digital precompensation), and Split NLC (an equal division of DBP between transmitter and receiver). For transmission over 100×100 km spans, the model predicts a 0.2 dB increase in SNR when applying Split NLC (versus DBP) to a single 32 GBd channel (from 0...
February 20, 2017: Optics Express
https://www.readbyqxmd.com/read/28219151/-the-disease-burden-for-low-back-pain-in-china-1990-and-2013
#20
W L Dong, Y C Li, S W Liu, Y Y Jiang, F Mao, L Qi, X Y Zeng, M G Zhou
Objective: To assess the disease burden for low back pain in China in 2013 and analyzed the change of it between 1990 and 2013. Methods: Data was from the Global Burden of Disease Study 2013 (GBD 2013). The burden of low back pain (LBP) among age groups, gender groups, provinces (excluding Taiwan China) groups was assessed by years lived with disability (YLD), including YLD, YLD rate, proportion of YLD due to LBP. The change of the YLD for LBP was analyzed between 1990 and 2013 by age-standardized YLD rate using the world standard population of 2000-2025 WHO...
February 6, 2017: Zhonghua Yu Fang Yi Xue za Zhi [Chinese Journal of Preventive Medicine]
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