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https://www.readbyqxmd.com/read/29050043/-malpractice-claims-against-pediatricians-analysis-of-expert-testimonies-from-the-medical-service-of-health-insurance-companies-between-2000-and-2014
#1
Heiko Steinhauer, Joachim Holzschuh, Thomas Böhler
Background In Germany, few data are available on medical malpractice claims against pediatricians. On behalf of Statutory Health Insurance Companies their Medical Service (MDK) regularly offers expert testimony in case of allegations during pediatric treatment. Methods Analysis of 374 written pediatric testimonies, documented between September 1st, 2000 and August 31st, 2014. Results 193 allegations against pediatricians were analysed separately for each sector of care (35% concerning outpatients, 28% normal inpatients, and 37% patients treated in an intensive care unit, ICU)...
October 19, 2017: Klinische Pädiatrie
https://www.readbyqxmd.com/read/29049929/aggression-emotional-self-regulation-attentional-bias-and-cognitive-inhibition-predict-risky-driving-behavior
#2
Susan Raouf Hadadi Sani, Zahra Tabibi, Javad Salehi Fadardi, Despina Stavrinos
The present study explored whether aggression, emotional regulation, cognitive inhibition, and attentional bias towards emotional stimuli were related to risky driving behavior (driving errors, and driving violations). A total of 117 applicants for taxi driver positions (89% male, M age=36.59years, SD=9.39, age range 24-62years) participated in the study. Measures included the Ahwaz Aggression Inventory, the Difficulties in emotion regulation Questionnaire, the emotional Stroop task, the Go/No-go task, and the Driving Behavior Questionnaire...
October 16, 2017: Accident; Analysis and Prevention
https://www.readbyqxmd.com/read/29049911/in-human-subject-specific-evaluation-of-a-control-theoretic-plasma-volume-regulation-model
#3
Ramin Bighamian, Michael Kinsky, George Kramer, Jin-Oh Hahn
The goal of this study was to conduct a subject-specific evaluation of a control-theoretic plasma volume regulation model in humans. We employed a set of clinical data collected from nine human subjects receiving fluid bolus with and without co-administration of an inotrope agent, including fluid infusion rate, plasma volume, and urine output. Once fitted to the data associated with each subject, the model accurately reproduced the fractional plasma volume change responses in all subjects: the error between actual versus model-reproduced fractional plasma volume change responses was only 1...
October 9, 2017: Computers in Biology and Medicine
https://www.readbyqxmd.com/read/29049907/clinical-correlates-of-saccadic-eye-movement-in-antipsychotic-na%C3%A3-ve-schizophrenia
#4
Aditi Subramaniam, Vijay Danivas, Sri Mahavir Agarwal, Sunil Kalmady, Venkataram Shivakumar, Anekal C Amaresha, Anushree Bose, Janardhanan C Narayanaswamy, Shivarama Varambally, Samuel B Hutton, Ganesan Venkatasubramanian, Bangalore N Gangadhar
Some aspects of saccadic performance have been found to be abnormal in chronic schizophrenia. The majority of this research has, however, been performed on patients treated with long-term antipsychotic medication. Very few studies have examined saccadic performance in antipsychotic-naïve/free patients. There are also very few studies describing the relationship between saccadic performance and clinical symptoms, particularly in antipsychotic free patients. In this study, we compared pro and antisaccade performance in a large sample of antipsychotic-naïve/free schizophrenia patients (N = 45) with healthy controls (N = 57)...
October 4, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/29049878/unifying-exchange-sensitivity-in-transition-metal-spin-state-ordering-and-catalysis-through-bond-valence-metrics
#5
Terry Z H Gani, Heather J Kulik
Accurate predictions of spin-state ordering, reaction energetics and barrier heights are critical for the computational discovery of open-shell transition metal (TM) catalysts. Semilocal approximations in density functional theory, such as the generalized gradient approximation (GGA), suffer from delocalization error that causes them to overstabilize strongly bonded states. Descriptions of energetics and bonding are often improved by introducing a fraction of exact exchange (e.g., erroneous low-spin GGA ground states instead correctly predicted as high-spin with a hybrid functional)...
October 19, 2017: Journal of Chemical Theory and Computation
https://www.readbyqxmd.com/read/29049811/effect-of-cone-reconstruction-on-right-ventricular-function-in-patients-with-ebstein-s-anomaly-a-meta-analysis
#6
Dongxu Li, Yasutaka Hirata, Xu Zhou, Akihiro Masuzawa, Minoru Ono, Qi An
OBJECTIVES: Cone reconstruction (CR) is a novel technique for surgically treating the tricuspid valve and right ventricle (RV) in patients with Ebstein's anomaly. However, precise changes in the RV function after CR remain unclear. This study aimed to evaluate the RV size and New York Heart Association (NYHA) functional class by conducting a meta-analysis of reported data. METHODS: The MEDLINE, EMBASE, Cochrane Library and China National Knowledge Infrastructure databases were searched for relevant studies...
September 23, 2017: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/29049731/factors-affecting-mydriasis-free-flicker-ergs-recorded-with-real-time-correction-for-retinal-illuminance-study-of-150-young-healthy-subjects
#7
Kumiko Kato, Mineo Kondo, Ryunosuke Nagashima, Asako Sugawara, Masahiko Sugimoto, Hisashi Matsubara, Daphne L McCulloch, Kengo Ikesugi
Purpose: A small, full-field flicker electroretinogram (ERG) recording system was recently developed to record flicker ERGs without mydriasis (RETeval). The device delivers a stimulus with constant retinal illuminance by adjusting the retinal luminance to compensate for changes in the pupillary area. The purpose of this study was to determine what factors affect the fundamental components of the flicker ERGs recorded by RETeval in young healthy subjects. Methods: Flicker ERGs were recorded with the RETeval system from 150 eyes of 150 young healthy subjects (age, 20-29 years)...
October 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/29049635/errors-in-table
#8
(no author information available yet)
No abstract text is available yet for this article.
October 19, 2017: JAMA Oncology
https://www.readbyqxmd.com/read/29049503/error-in-figure
#9
(no author information available yet)
No abstract text is available yet for this article.
October 1, 2017: JAMA Cardiology
https://www.readbyqxmd.com/read/29049445/error-in-conflicts-of-interest-disclosures
#10
(no author information available yet)
No abstract text is available yet for this article.
October 11, 2017: JAMA Cardiology
https://www.readbyqxmd.com/read/29049406/distinct-prediction-errors-in-mesostriatal-circuits-of-the-human-brain-mediate-learning-about-the-values-of-both-states-and-actions-evidence-from-high-resolution-fmri
#11
Jaron T Colas, Wolfgang M Pauli, Tobias Larsen, J Michael Tyszka, John P O'Doherty
Prediction-error signals consistent with formal models of "reinforcement learning" (RL) have repeatedly been found within dopaminergic nuclei of the midbrain and dopaminoceptive areas of the striatum. However, the precise form of the RL algorithms implemented in the human brain is not yet well determined. Here, we created a novel paradigm optimized to dissociate the subtypes of reward-prediction errors that function as the key computational signatures of two distinct classes of RL models-namely, "actor/critic" models and action-value-learning models (e...
October 19, 2017: PLoS Computational Biology
https://www.readbyqxmd.com/read/29049369/discrimination-and-prediction-of-cultivation-age-and-parts-of-panax-ginseng-by-fourier-transform-infrared-spectroscopy-combined-with-multivariate-statistical-analysis
#12
Byeong-Ju Lee, Hye-Youn Kim, Sa Rang Lim, Linfang Huang, Hyung-Kyoon Choi
Panax ginseng C.A. Meyer is a herb used for medicinal purposes, and its discrimination according to cultivation age has been an important and practical issue. This study employed Fourier-transform infrared (FT-IR) spectroscopy with multivariate statistical analysis to obtain a prediction model for discriminating cultivation ages (5 and 6 years) and three different parts (rhizome, tap root, and lateral root) of P. ginseng. The optimal partial-least-squares regression (PLSR) models for discriminating ginseng samples were determined by selecting normalization methods, number of partial-least-squares (PLS) components, and variable influence on projection (VIP) cutoff values...
2017: PloS One
https://www.readbyqxmd.com/read/29049339/reliability-of-transcardiopulmonary-thermodilution-cardiac-output-measurement-in-experimental-aortic-valve-insufficiency
#13
Martin Petzoldt, Constantin J Trepte, Jan Ridder, Stefan Maisch, Philipp Klapsing, Jan F Kersten, Hans Peter Richter, Jens C Kubitz, Daniel A Reuter, Matthias S Goepfert
BACKGROUND: Monitoring cardiac output (CO) is important to optimize hemodynamic function in critically ill patients. The prevalence of aortic valve insufficiency (AI) is rising in the aging population. However, reliability of CO monitoring techniques in AI is unknown. The aim of this study was to investigate the impact of AI on accuracy, precision, and trending ability of transcardiopulmonary thermodilution-derived COTCPTD in comparison with pulmonary artery catheter thermodilution COPAC...
2017: PloS One
https://www.readbyqxmd.com/read/29049325/effect-of-therapeutic-interchange-on-medication-reconciliation-during-hospitalization-and-upon-discharge-in-a-geriatric-population
#14
Jessica S Wang, Robert L Fogerty, Leora I Horwitz
BACKGROUND: Therapeutic interchange of a same class medication for an outpatient medication is a widespread practice during hospitalization in response to limited hospital formularies. However, therapeutic interchange may increase risk of medication errors. The objective was to characterize the prevalence and safety of therapeutic interchange. METHODS AND FINDINGS: Secondary analysis of a transitions of care study. We included patients over age 64 admitted to a tertiary care hospital between 2009-2010 with heart failure, pneumonia, or acute coronary syndrome who were taking a medication in any of six commonly-interchanged classes on admission: proton pump inhibitors (PPIs), histamine H2-receptor antagonists (H2 blockers), hydroxymethylglutaryl CoA reductase inhibitors (statins), angiotensin-converting enzyme (ACE) inhibitors, angiotensin receptor blockers (ARBs), and inhaled corticosteroids (ICS)...
2017: PloS One
https://www.readbyqxmd.com/read/29049312/impact-of-annotation-error-in-%C3%AE-globin-genes-on-molecular-diagnosis
#15
J Francis Borgio
BACKGROUND: Recent studies on the variants in duplicated human alpha globin genes (HBA2 and HBA1) actively target the α-globin gene as molecular modulators for the treatment of β-thalassemia major. Identification of the exact position of variant in HBA1, HBA2 or its patchworks is mandatory to support the therapeutic aims in β-thalassemia major, by identifying specific modulators for the reactivation of fetal hemoglobin production. Hence, accurate identification of the variants in α-globin genes is crucial for the proper diagnosis, treatment and genetic counseling...
2017: PloS One
https://www.readbyqxmd.com/read/29049144/the-etiology-of-neuronal-development-in-craniosynostosis-a-working-hypothesis
#16
Eric D Brooks, Joel S Beckett, Jenny Yang, Andrew T Timberlake, Alexander H Sun, Carolyn Chuang, John A Persing
Craniosynostosis is one of the most common craniofacial conditions treated by neurologic and plastic surgeons. In addition to disfigurement, children with craniosynostosis experience significant cognitive dysfunction later in life. Surgery is performed in infancy to correct skull deformity; however, the field is at a crossroads regarding the best approach for correction. Since the cause of brain dysfunction in these patients has remained uncertain, the role and type of surgery might have in attenuating the later-observed cognitive deficits through impact on the brain has been unclear...
October 18, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/29049070/noninfectious-fever-in-the-near-term-pregnant-rat-induces-fetal-brain-inflammation-a-model-for-the-consequences-of-epidural-associated-maternal-fever
#17
Scott Segal, Carlo Pancaro, Iwona Bonney, James E Marchand
BACKGROUND: Women laboring with epidural analgesia experience fever much more frequently than do women who chose other forms of analgesia, and maternal intrapartum fever is associated with numerous adverse consequences, including brain injury in the fetus. We developed a model of noninfectious inflammatory fever in the near-term pregnant rat to simulate the pathophysiology of epidural-associated fever and hypothesized that it would produce fetal brain inflammation. METHODS: Twenty-four pregnant Sprague-Dawley rats were studied at 20 days gestation (term: 22 days)...
October 17, 2017: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/29049016/skeletal-muscle-ultrasonography-in-nutrition-and-functional-outcome-assessment-of-critically-ill-children-experience-and-insights-from-pediatric-disease-and-adult-critical-care-studies-formula-see-text
#18
Chengsi Ong, Jan Hau Lee, Melvin K S Leow, Zudin A Puthucheary
Evidence suggests that critically ill children develop muscle wasting, which could affect outcomes. Muscle ultrasound has been used to track muscle wasting and association with outcomes in critically ill adults but not children. This review aims to summarize methodological considerations of muscle ultrasound, structural findings, and possibilities for its application in the assessment of nutrition and functional outcomes in critically ill children. Medline, Embase, and CINAHL databases were searched up until April 2016...
September 2017: JPEN. Journal of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/29048843/-analysis-of-hydrogen-isotopes-by-gas-chromatography-using-a-mncl2-coated-%C3%AE-al2o3-capillary-packed-column
#19
Ping Chen, Xiaolong Fu, Peng Hu, Chengjian Xiao, Xingbi Ren, Xiulong Xia, Heyi Wang
The conventional packed column gas chromatographic analysis of hydrogen isotopes has low column efficiency, broad peak and long retention time. In this work, a γ-Al2O3 with MnCl2 coated capillary packed column was tested at cryogenic temperature. The systematic column efficiency analysis and the hydrogen isotopes analytical technique research had been carried out. The results showed that, the γ-Al2O3 with MnCl2 coating could greatly improve the surface degree of order, pore structure and adsorption properties...
July 8, 2017: Se Pu, Chinese Journal of Chromatography
https://www.readbyqxmd.com/read/29048797/-hydrogen-isotopes-analysis-by-gas-chromatography-using-metal-organic-framework-cpl-1-packed-column
#20
Peng Hu, Ping Chen, Dawei Cao, Xiaolong Fu, Chengjian Xiao, Heyi Wang
CPL-1 is a metal organic framework (MOF) with potential application as stationary phase material in gas chromatographic (GC) analysis, due to its large specific surface area, uniform pore size and good quantum sieving effect on hydrogen isotopes at low temperatures. Herein, a microporous column packed with CPL-1 was used at cryogenic temperature (77 K), and the column was 1.0 mm in inner diameter, 0.5 m in length. Single crystals of Al2O3 was used to build flow path for chromatographic carrier gas. The results showed that the adsorption of H2 and D2 with CPL-1 was 4 mmol/g at 77 K, which was better than MnCl2/γ -Al2O3 and γ -Al2O3...
October 8, 2017: Se Pu, Chinese Journal of Chromatography
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