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Si-Si Sun, Zheng Wang, Xiang Wen Wu, Jian-Hua Zhang, Chao-Jie Li, Shao-Yun Yin, Ling Chen, Mei Pan, Cheng-Yong Su
Two series of isostructural lanthanide coordination complexes, namely, LIFM-42(Ln), Ln = Eu, Tb, Gd, and LIFM-43(Ln), Ln = Er, Yb) were synthesized through the self-assembly of an ESIPT (excited-state intramolecular proton transfer) ligand, H2hpi2cf (5-(2-(5-fluoro-2-hydroxyphenyl)-4,5-bis(4-fluorophenyl)-1H-imidazol-1-yl)isophthalic acid) with different lanthanide ions. In the coordination structures linked by the ligands and oxo-bridged LnIII2 clusters (for LIFM-42(Ln) series) or isolated LnIII ions (for LIFM-43(Ln) series), the ESIPT ligand can serve as both the host and antenna for protecting and sensitizing the photoluminescence (PL) of LnIII ions...
May 22, 2018: Chemistry: a European Journal
Jiong Li, Xuandong Wang, Dongye Zheng, Xinyi Lin, Zuwu Wei, Da Zhang, Zhuanfang Li, Yun Zhang, Ming Wu, Xiaolong Liu
Theranostic nanoprobes integrated with dual-modal imaging and therapeutic functions, such as photodynamic therapy (PDT), have exhibited significant potency in cancer treatments due to their high imaging accuracy and non-invasive advantages for cancer elimination. However, biocompatibility and highly efficient accumulation of these nanoprobes in tumor are still unsatisfactory for clinical application. In this study, a photosensitizer -loaded magnetic nanobead with surface further coated with a layer of cancer cell membrane (SSAP-Ce6@CCM) was designed to improve the biocompatibility and cellular uptake and ultimately achieve enhanced MR/NIR fluorescence imaging and PDT efficacy...
May 22, 2018: Biomaterials Science
Xiaoli Luan, Minjun Jin, Fei Liu
The fault detection problem of the oil desalting process is investigated in this paper. Different from the traditional fault detection approaches based on measurable process variables, near-infrared (NIR) spectroscopy is applied to acquire the process fault information from the molecular vibrational signal. With the molecular spectra data, principal component analysis was explored to calculate the Hotelling T2 and squared prediction error, which act as fault indicators. Compared with the traditional fault detection approach based on measurable process variables, NIR spectra-based fault detection illustrates more sensitivity to early failure because of the fact that the changes in the molecular level can be identified earlier than the physical appearances on the process...
January 1, 2018: Applied Spectroscopy
Andreas Melfsen, Max Holstermann, Angelika Haeussermann, Joachim Molkentin, Andreas Susenbeth, Eberhard Hartung
Near infrared spectroscopy (NIRS) has the potential to estimate contents of fatty acids (FA) in milk frequently at-farm or during daily milking routine. In this study, a total of 738 raw milk spectra collected from 33 Holstein cows over a period of 30 weeks were recorded. Reference data on FA composition in milk and in milk fat were analysed in laboratory. Calibration models were calculated for single FA and groups of FA in milk and in milk fat. Validation resulted in sufficient Ratio of Prediction to Deviation (RPD) values for some single FA and in higher RPD values for groups of FA when concentrations of FA in milk were predicted...
May 2018: Journal of Dairy Research
Matthias Bock, Pascal Eich, Stephan Kucera, Matthias Kreis, Andreas Lenhard, Christoph Becher, Jürgen Eschner
Entanglement between a stationary quantum system and a flying qubit is an essential ingredient of a quantum-repeater network. It has been demonstrated for trapped ions, trapped atoms, color centers in diamond, or quantum dots. These systems have transition wavelengths in the blue, red or near-infrared spectral regions, whereas long-range fiber-communication requires wavelengths in the low-loss, low-dispersion telecom regime. A proven tool to interconnect flying qubits at visible/NIR wavelengths to the telecom bands is quantum frequency conversion...
May 21, 2018: Nature Communications
Avner Thaler, Noa Bregman, Tanya Gurevich, Tamara Shiner, Yonatan Dror, Ofir Zmira, Ziv Gan-Or, Anat Bar-Shira, Mali Gana-Weisz, Avi Orr-Urtreger, Nir Giladi, Anat Mirelman
OBJECTIVE: Mutations in the glucocerebrosidase (GBA) gene are divided into mild and severe (mGBA, sGBA) based on their contribution to the phenotype of Gaucher disease (GD) among homozygotes. We conducted a longitudinal analysis of Parkinson's disease (PD) patients carrying mutations in the GBA gene to better characterize genotype-phenotype correlations. METHODS: Patients underwent a comprehensive assessment of medical, neurological, cognitive and non-motor functions...
May 17, 2018: Parkinsonism & related Disorders
İbrahim Sani Özdemir, Bülent Öztürk, Belgin Çelik, Yüksel Sarıtepe, Hatice Aksoy
The potential of using FT-NIR spectroscopy for the rapid and non-destructive measurement of the moisture, water activity, firmness and SO2 content of the intact sulphured-dried apricots (SDA) was investigated for the first time in the literature. The partial least squares regression (PLS-R) models constructed using FT-NIR spectra were very successful in predicting the moisture content (R2 p = 0.986, RMSEP = 1.22%, RPD = 9.15) and water activity (R2 p = 0.987, RMSEP = 0.016, RPD = 9.37) of SDAs. Satisfactory results were also obtained for the models developed for the prediction of the firmness (R2 p = 0...
August 15, 2018: Talanta
Cláudia A Teixeira Dos Santos, Ricardo N M J Páscoa, Patrícia A L S Porto, António L Cerdeira, J M González-Sáiz, C Pizarro, João A Lopes
Routine wine analysis are commonly employed to ensure the quality and safety standards, and to meet consumers' demands and legal requirements. In the last decades, efforts have been done in order to replace the traditional analytical techniques by vibrational spectroscopic techniques such as near infrared (NIR) and mid infrared (MIR) spectroscopy. The potential of these techniques has already been proved by several studies that revealed their ability for the determination of several wine parameters with high levels of precision and accuracy...
August 15, 2018: Talanta
Fanli Xu, Mengxue Liu, Xin Li, Zhijuan Xiong, Xueyan Cao, Xiangyang Shi, Rui Guo
The combination of photothermal therapy (PTT) and photodynamic therapy (PDT) in cancer treatment has attracted much attention in recent years. However, developing highly efficient and targeted therapeutic nanoagents for amplifying PTT and PDT treatments remains challenging. In this work, we developed a novel photothermal and photodynamic therapeutic nanoplatform for treatment of cancer cells overexpressing integrin αv β₃ through the coating of polydopamine (PDA) on indocyanine green (ICG)-loaded laponite (LAP) and then further conjugating polyethylene glycol-arginine-glycine-aspartic acid (PEG-RGD) as targeted agents on the surface...
May 19, 2018: Nanomaterials
Hailong Qiu, Meiling Tan, Tymish Y Ohulchanskyy, Jonathan F Lovell, Guanying Chen
Photodynamic therapy (PDT) is a minimally invasive cancer modality that combines a photosensitizer (PS), light, and oxygen. Introduction of new nanotechnologies holds potential to improve PDT performance. Upconversion nanoparticles (UCNPs) offer potentially advantageous benefits for PDT, attributed to their distinct photon upconverting feature. The ability to convert near-infrared (NIR) light into visible or even ultraviolet light via UCNPs allows for the activation of nearby PS agents to produce singlet oxygen, as most PS agents absorb visible and ultraviolet light...
May 18, 2018: Nanomaterials
Carlos Eduardo M Braz, Manuel Antonio C Jacinto, Edenir R Pereira-Filho, Gilberto B Souza, Ana Rita A Nogueira
Models using near-infrared spectroscopy (NIRS) were constructed based on physical-mechanical tests to determine the quality of cattle leather. The following official parameters were used, considering the industry requirements: tensile strength (TS), percentage elongation (%E), tear strength (TT), and double hole tear strength (DHS). Classification models were constructed with the use of k-nearest neighbor (kNN), soft independent modeling of class analogy (SIMCA), and partial least squares-discriminant analysis (PLS-DA)...
May 9, 2018: Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy
Silvia Erika Kober, Vanessa Hinterleitner, Günther Bauernfeind, Christa Neuper, Guilherme Wood
We investigated the trainability of the hemodynamic response as assessed with near-infrared spectroscopy (NIRS) during one neurofeedback (NF) session. Forty-eight participants were randomly assigned to four different groups that tried to either increase or decrease oxygenated (oxy-Hb) or deoxygenated hemoglobin (deoxy-Hb) over the inferior frontal gyrus during imagery of swallowing movements. Deoxy-Hb could be successfully up-regulated while oxy-Hb could be successfully down-regulated during NF. Participants were not able to down-regulate deoxy-Hb or to up-regulate oxy-Hb...
May 18, 2018: Biological Psychology
Jinyoung Kang, Dokyoung Kim, Junxin Wang, Yunho Han, Jonathan M Zuidema, Ali Hariri, Ji-Ho Park, Jesse V Jokerst, Michael J Sailor
Photoacoustic (PA) imaging allows visualization of the physiology and pathology of tissues with good spatial resolution and relatively deep tissue penetration. The method converts near-infrared (NIR) laser excitation into thermal expansion, generating pressure transients that are detected with an acoustic transducer. Here, we find that the response of the PA contrast agent indocyanine green (ICG) can be enhanced 17-fold when it is sealed within a rigid nanoparticle. ICG encapsulated in particles composed of porous silicon (pSiNP), porous silica, or calcium silicate all show greater PA contrast relative to equivalent quantities of free ICG, with the pSiNPs showing the strongest enhancement...
May 21, 2018: Advanced Materials
Ryan J Healy, Andres Zorrilla-Vaca, Wendy Ziai, Marek A Mirski, Charles W Hogue, Romergryko Geocadin, Batya Radzik, Caitlin Palmisano, Lucia Rivera-Lara
BACKGROUND: The Glasgow Coma Scale (GCS) is an essential coma scale in critical care for determining the neurological status of patients and for estimating their long-term prognosis. Similarly, cerebral autoregulation (CA) monitoring has shown to be an accurate technique for predicting clinical outcomes. However, little is known about the relationship between CA measurements and GCS scores among neurological critically ill patients. This study aimed to explore the association between noninvasive CA multimodal monitoring measurements and GCS scores...
May 18, 2018: Journal of Neurosurgical Anesthesiology
Parikshit Sahatiya, Akash Shinde, Sushmee Badhulika
Even though 2D ZnO has been utilized for enhanced self-powered sensing by strain modulation due to its piezoelectric property, study on utilizing pyroelectric property of ZnO remains unexplored. The piezoelectric property of 2D ZnO works on mechanical strain which disrupts the structure of ZnO leading to the failure of device. For pyroelectric nanogenerator, temperature difference can be triggered by external light source which does not disrupt the ZnO structure and also avoids the need for physical bending/pressing as in case of piezoelectric nanogenerator...
May 21, 2018: Nanotechnology
Yuki Inoue, Daisuke Sakamaki, Yusuke Tsutsui, Masayuki Gon, Yoshiki Chujo, Shu Seki
The tetramers of azapentacene derivatives with unique hash mark (#)-shaped structures were prepared in a quite facile manner. The #-shaped tetramers are optically active because of possessing extended biaryl skeletons, and the structure of the tetramer composed of four dihydrodiazapentacene (DHDAP) units (1) was investigated as the first example of this kind of molecule. The tetramer 1 showed characteristic chiroptical properties reflecting its orthogonally arranged quadruple DHDAP moieties, as well as redox activity...
May 21, 2018: Journal of the American Chemical Society
Bernhard Schwaberger, Gerhard Pichler, Corinna Binder-Heschl, Nariae Baik-Schneditz, Alexander Avian, Berndt Urlesberger
Background: Recently, we demonstrated that in healthy newborn infants cerebral blood volume (CBV) was decreasing continuously after birth. We hypothesized that this was due to the increase in oxygen delivery to the brain during neonatal transition. Thus delayed cerebral oxygen delivery in infants in need for respiratory support (RS) during postnatal stabilization might influence changes in CBV. Objective: Aim of the study was to evaluate transitional changes in CBV immediately after birth in term and preterm infants with and without need of RS...
2018: Frontiers in Pediatrics
Jingjing Zhang, Hang Xing, Yi Lu
While it has been well recognized that affordable and pocket-size devices play a major role in environmental monitoring, food safety and medical diagnostics, it often takes a tremendous amount of resources to develop such devices. Devices that have been developed are often dedicated devices that can detect only one or a few targets. To overcome these limitations, we herein report a novel target-responsive smart thermometer for translating molecular detection into a temperature test. The sensor system consists of a functional DNA-phospholipase A2 (PLA2 ) enzyme conjugate, a liposome-encapsulated NIR dye, and a thermometer interfaced with a NIR-laser device...
April 28, 2018: Chemical Science
Yingying Ning, Juan Tang, Yi-Wei Liu, Jing Jing, Yuansheng Sun, Jun-Long Zhang
Herein, we report the design and synthesis of biocompatible Yb3+ complexes for near-infrared (NIR) living cell imaging. Upon excitation at either the visible (Soret band) or red region (Q band), these β-fluorinated Yb3+ complexes display high NIR luminescence (quantum yields up to 23% and 13% in dimethyl sulfoxide and water, respectively) and have higher stabilities and prolonged decay lifetimes (up to 249 μs) compared to the β-non-fluorinated counterparts. This renders the β-fluorinated Yb3+ complexes as a new class of biological optical probes in both steady-state imaging and time-resolved fluorescence lifetime imaging (FLIM)...
April 21, 2018: Chemical Science
Michael A Evans, Po-Ju Huang, Yuji Iwamoto, Kelly N Ibsen, Emory M Chan, Yutaka Hitomi, Peter C Ford, Samir Mitragotri
Nitric oxide (NO) holds great promise as a treatment for cancer hypoxia, if its concentration and localization can be precisely controlled. Here, we report a "Trojan Horse" strategy to provide the necessary spatial, temporal, and dosage control of such drug-delivery therapies at targeted tissues. Described is a unique package consisting of (1) a manganese-nitrosyl complex, which is a photoactivated NO-releasing moiety (photoNORM), plus Nd3+ -doped upconverting nanoparticles (Nd-UCNPs) incorporated into (2) biodegradable polymer microparticles that are taken up by (3) bone-marrow derived murine macrophages...
April 21, 2018: Chemical Science
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