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https://www.readbyqxmd.com/read/28102947/a-feasibility-study-of-an-integrated-nir-gamma-visible-imaging-system-for-endoscopic-sentinel-lymph-node-mapping
#1
Han Gyu Kang, Ho-Young Lee, Kyeong Min Kim, Seong-Hyun Song, Gun Chul Hong, Seong Jong Hong
PURPOSE: The aim of this study is to integrate NIR, gamma, and visible imaging tools into a single endoscopic system to overcome the limitation of NIR using gamma imaging and to demonstrate the feasibility of endoscopic NIR/gamma/visible fusion imaging for sentinel lymph node (SLN) mapping with a small animal. METHODS: The endoscopic NIR/gamma/visible imaging system consists of a tungsten pinhole collimator, a plastic focusing lens, a BGO crystal (11 × 11 × 2 mm(3) ), a fiber-optic taper (front = 11 × 11 mm(2) , end = 4 × 4 mm(2) ), a 122-cm long endoscopic fiber bundle, an NIR emission filter, a relay lens, and a CCD camera...
January 2017: Medical Physics
https://www.readbyqxmd.com/read/28101804/white-matter-hyperintensities-correlate-to-cognition-and-fiber-tract-integrity-in-older-adults-with-hiv
#2
Christa Watson, Edgar Busovaca, Jessica M Foley, I Elaine Allen, Christopher G Schwarz, Neda Jahanshad, Talia M Nir, Pardis Esmaeili-Firidouni, Benedetta Milanini, Howard Rosen, Owen T Carmichael, Paul M Thompson, Victor G Valcour
Our aim was to examine the clinical relevance of white matter hyperintensities (WMH) in HIV. We used an automated approach to quantify WMH volume in HIV seropositive (HIV+; n = 65) and HIV seronegative (HIV-; n = 29) adults over age 60. We compared WMH volumes between HIV+ and HIV- groups in cross-sectional and multiple time-point analyses. We also assessed correlations between WMH volumes and cardiovascular, HIV severity, cognitive scores, and diffusion tensor imaging variables. Serostatus groups did not differ in WMH volume, but HIV+ participants had less cerebral white matter (mean: 470...
January 18, 2017: Journal of Neurovirology
https://www.readbyqxmd.com/read/28101544/tetrathienyl-functionalized-red-and-nir-absorbing-bodipy-dyes-appending-various-peripheral-substituents
#3
Ping Liu, Feng Gao, Lina Zhou, Yu Chen, Zhijian Chen
A series of boron-dipyrromethene dyes (BODIPYs) 4a-g with different thienyl moieties at 2,3,5,6-positions of the BODIPY core were synthesized by the Stille cross-coupling reaction. The new compounds were characterized by (1)H NMR, (13)C NMR, HRMS, and IR spectroscopy. The single crystal structure of compound 4e was obtained by X-ray crystallography. The optical and electrochemical properties of these dyes were studied by UV/Vis spectroscopy, fluorescence spectroscopy, and cyclic voltammetry. The DFT calculation of the frontier molecular orbitals of these dyes corroborates the observed effects of peripheral substituents on the optical and redox properties...
January 19, 2017: Organic & Biomolecular Chemistry
https://www.readbyqxmd.com/read/28101413/significant-and-sustaining-elevation-of-blood-oxygen-induced-by-chinese-cupping-therapy-as-assessed-by-near-infrared-spectroscopy
#4
Ting Li, Yaoxian Li, Yu Lin, Kai Li
Cupping therapy has been used in traditional Chinese medicine for thousands of years to relieve muscle pain/tendency/fatigue and to cure or reduce symbols of other diseases. However, its therapeutic effect is sparsely interpreted in the language of modern physiology. To objectively evaluate its therapeutic effect, we focused on dry cupping treatment and utilized near-infrared spectroscopy (NIRS) to assess the concentration change in oxy-hemoglobin ([HbO2]), deoxy-hemoglobin ([Hb]), and blood volume in the course of cupping therapy over 13 volunteers on the infraspinatus muscle, where is usually applied for shoulder pains...
January 1, 2017: Biomedical Optics Express
https://www.readbyqxmd.com/read/28099981/use-of-esophageal-hemoximetry-to-assess-the-effect-of-packed-red-blood-cell-transfusion-on-gastrointestinal-oxygenation-in-newborn-infants
#5
Farha M Vora, Judy Gates, Kimberley Gerard, Shawn Hanson, Richard L Applegate, Arlin B Blood
Objectives There are no widely accepted methods of continuously monitoring gut oxygenation in the newborn during packed red blood cell transfusion. We investigated the use of an orally inserted light spectroscopy probe to measure lower esophageal oxyhemoglobin saturations (eStO2) before, during, and after transfusion and made comparisons with abdominal near-infrared spectroscopy (NIRS) and superior mesenteric artery (SMA) flow. Study Design Thirteen neonates with corrected gestational ages ranging from 22 weeks, 0 day to 37 weeks, 5 days were enrolled...
January 18, 2017: American Journal of Perinatology
https://www.readbyqxmd.com/read/28099170/exploring-the-ability-of-the-nalidixate-to-sensitize-visible-and-near-infrared-emitting-lanthanide-iii-cations
#6
Svetlana V Eliseeva, Valerii S Liasotkyi, Iurii P Golovach, Pavel G Doga, Valery P Antonovich, Stéphane Petoud, Svetlana B Meshkova
Recently, a strong interest has been directed towards near-infrared (NIR) emitting lanthanide(III) compounds as they do possess complementary advantages in respect to organic molecules and semi-conductor nanocrystals, especially in the fields of biological analysis and imaging. To benefit from their emission, a key requirement to fulfill is the sensitization of lanthanide(III) cations with an appropriate chromophore. This condition is especially challenging to address for the lanthanide(III) cations emitting in the NIR...
January 18, 2017: Methods and Applications in Fluorescence
https://www.readbyqxmd.com/read/28098986/investigation-of-the-energy-transfer-mechanism-in-ho-3-and-yb-3-codoped-lu2o3-phosphor-with-efficient-near-infrared-downconversion
#7
Guotao Xiang, Yan Ma, Xianju Zhou, Sha Jiang, Li Li, Xiaobing Luo, Zhendong Hao, Xia Zhang, Guo-Hui Pan, Yongshi Luo, Jiahua Zhang
A high-temperature solid-state method was used to synthesize the Ho(3+)- and Yb(3+)-codoped cubic Lu2O3 powders. The crystal structures of the as-prepared powders were characterized by X-ray diffraction. The energy-transfer (ET) phenomenon between Ho(3+) ions and Yb(3+) ions was verified by the steady-state spectra including visible and near-infrared (NIR) regions. Beyond that, the decay curves were also measured to certify the existence of the ET process. The downconversion phenomena appeared when the samples were excited by 446 nm wavelength corresponding to the transition of Ho(3+): (5)I8→(5)G6/(5)F1...
January 18, 2017: Inorganic Chemistry
https://www.readbyqxmd.com/read/28098797/nonlinear-fusion-of-multispectral-citrus-fruit-image-data-with-information-contents
#8
Peilin Li, Sang-Heon Lee, Hung-Yao Hsu, Jae-Sam Park
The main issue of vison-based automatic harvesting manipulators is the difficulty in the correct fruit identification in the images under natural lighting conditions. Mostly, the solution has been based on a linear combination of color components in the multispectral images. However, the results have not reached a satisfactory level. To overcome this issue, this paper proposes a robust nonlinear fusion method to augment the original color image with the synchronized near infrared image. The two images are fused with Daubechies wavelet transform (DWT) in a multiscale decomposition approach...
January 13, 2017: Sensors
https://www.readbyqxmd.com/read/28098451/the-effect-of-injection-layer-sub-bandgap-states-on-electron-injection-in-organic-light-emitting-diodes
#9
Carsten Hinzmann, Osnat Magen, Yvonne J Hofstetter, Paul Edward Hopkinson, Nir Tessler, Yana Vaynzof
It is generally considered that the injection of charges into an active layer of an organic light-emitting diode (OLED) is solely determined by the energetic injection barrier formed at the device interfaces. Here, we demonstrate that the density of surface states of the electron-injecting ZnO layer has a profound effect on both the charge injection and the overall performance of the OLED device. Introducing a dopant into ZnO reduces both the energy depth and density of surface states without altering the position of the energy levels - thus the magnitude of the injection barrier formed at the organic/ZnO interface remains unchanged...
January 18, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28098285/kb-po4-f-a-novel-acentric-deep-ultraviolet-material
#10
Ji-Hong Jiang, Lin-Chuan Zhang, Ya-Xi Huang, Zhi-Mei Sun, Yuanming Pan, Jin-Xiao Mi
Two challenges to grow KBe2BO3F2 (KBBF), the best known deep-ultraviolet nonlinear optical (NLO) material to date, are the limited crystal sizes and the use of a highly toxic element (Be). Herein we report on the discovery of a novel anhydrous non-centrosymmetric alkali fluorinated borophosphate KB(PO4)F (KBPF) featuring a cut-off wavelength of less than 200 nm and a large second-harmonic generation (SHG) effect similar to KH2PO4 (KDP), hence representing a new promising deep-ultraviolet NLO material. The KBPF crystals consisting of common elements can be grown using green and cost effective processes and do not show any detectable hygroscopicity...
January 18, 2017: Dalton Transactions: An International Journal of Inorganic Chemistry
https://www.readbyqxmd.com/read/28098276/direct-white-light-emitting-and-near-infrared-phosphorescence-of-zeolitic-imidazolate-framework-8
#11
Xiaogang Yang, Dongpeng Yan
Zeolitic imidazolate framework-8 directly exhibits unexpected white-light emission and near-infrared (NIR) phosphorescence, due to the host-guest interaction and the alternation of electron-density distribution, as confirmed by both experimental and computational studies.
January 18, 2017: Chemical Communications: Chem Comm
https://www.readbyqxmd.com/read/28098272/a-near-infrared-light-responsive-c-di-gmp-module-based-and-logic-gate-in-shewanella-oneidensis
#12
Yidan Hu, Yichao Wu, Manisha Mukherjee, Bin Cao
A novel, biofilm-based AND logic gate was constructed in Shewanella oneidensis through a near-infrared (NIR) light responsive c-di-GMP module. The logic gate was demonstrated in microbial fuel cells with isopropyl β-d-thiogalactoside (IPTG) and NIR light as the inputs and electrical signals as the output.
January 18, 2017: Chemical Communications: Chem Comm
https://www.readbyqxmd.com/read/28098266/self-assembled-lipoprotein-based-gold-nanoparticles-for-detection-and-photothermal-disaggregation-of-%C3%AE-amyloid-aggregates
#13
P A T Martins, S Alsaiari, K Julfakyan, Z Nie, N M Khashab
We present a reconstituted lipoprotein-based nanoparticle platform comprising a curcumin fluorescent motif and an NIR responsive gold core. This multifunctional nanosystem is successfully used for aggregation-dependent fluorescence detection and photothermal disassembly of insoluble amyloid aggregates.
January 18, 2017: Chemical Communications: Chem Comm
https://www.readbyqxmd.com/read/28096386/molecular-imaging-of-biological-systems-with-a-clickable-dye-in-the-broad-800-to-1-700-nm-near-infrared-window
#14
Shoujun Zhu, Qinglai Yang, Alexander L Antaris, Jingying Yue, Zhuoran Ma, Huasen Wang, Wei Huang, Hao Wan, Joy Wang, Shuo Diao, Bo Zhang, Xiaoyang Li, Yeteng Zhong, Kuai Yu, Guosong Hong, Jian Luo, Yongye Liang, Hongjie Dai
Fluorescence imaging multiplicity of biological systems is an area of intense focus, currently limited to fluorescence channels in the visible and first near-infrared (NIR-I; ∼700-900 nm) spectral regions. The development of conjugatable fluorophores with longer wavelength emission is highly desired to afford more targeting channels, reduce background autofluorescence, and achieve deeper tissue imaging depths. We have developed NIR-II (1,000-1,700 nm) molecular imaging agents with a bright NIR-II fluorophore through high-efficiency click chemistry to specific molecular antibodies...
January 17, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28094402/mesoporous-carbon-nanoshells-for-high-hydrophobic-drug-loading-multimodal-optical-imaging-controlled-drug-release-and-synergistic-therapy
#15
Hui Wang, Kui Wang, Qingxin Mu, Zachary R Stephen, Yanyan Yu, Shuiqin Zhou, Miqin Zhang
Loading and controlled release of sufficient hydrophobic drugs to tumor cells has been the bottleneck in chemotherapy for decades. Herein we report the development of a fluorescent and mesoporous carbon nanoshell (FMP-CNS) that exhibits a loading capacity for the hydrophobic drug paclitaxel (PTX) as high as ∼80 wt% and releases the drug in a controllable fashion under NIR irradiation (825 nm) at an intensity of 1.5 W cm(-2). The high drug loading is primarily attributed to its mesoporous structure and to the supramolecular π-stacking between FMP-CNSs and PTX molecules...
January 17, 2017: Nanoscale
https://www.readbyqxmd.com/read/28094261/beyond-the-margins-real-time-detection-of-cancer-using-targeted-fluorophores
#16
REVIEW
Ray R Zhang, Alexandra B Schroeder, Joseph J Grudzinski, Eben L Rosenthal, Jason M Warram, Anatoly N Pinchuk, Kevin W Eliceiri, John S Kuo, Jamey P Weichert
Over the past two decades, synergistic innovations in imaging technology have resulted in a revolution in which a range of biomedical applications are now benefiting from fluorescence imaging. Specifically, advances in fluorophore chemistry and imaging hardware, and the identification of targetable biomarkers have now positioned intraoperative fluorescence as a highly specific real-time detection modality for surgeons in oncology. In particular, the deeper tissue penetration and limited autofluorescence of near-infrared (NIR) fluorescence imaging improves the translational potential of this modality over visible-light fluorescence imaging...
January 17, 2017: Nature Reviews. Clinical Oncology
https://www.readbyqxmd.com/read/28094161/disinhibition-in-children-with-attention-deficit-hyperactivity-disorder-changes-in-oxy-hb-on-near-infrared-spectroscopy-during-rock-paper-scissors-task
#17
Sayaka Ishii, Yoshimi Kaga, Tomoko Tando, Kakuro Aoyagi, Fumikazu Sano, Hideaki Kanemura, Kanji Sugita, Masao Aihara
OBJECTIVE: Attention-deficit/hyperactivity disorder (AD/HD) is a common developmental disorder. Many reports have suggested that symptoms of AD/HD are related to frontal lobe dysfunctions, particularly disinhibition. However, measuring neurological findings with biomarkers during frontal functional tasks has sometimes been difficult in children with AD/HD. This study aimed to investigate frontal inhibitory function objectively in children with AD/HD during "rock, paper, scissors" (RPS) tasks, as a familiar game for Japanese children, using near-infrared spectroscopy (NIRS)...
January 13, 2017: Brain & Development
https://www.readbyqxmd.com/read/28093899/crucial-role-of-donor-density-in-the-performance-of-oxynitride-perovskite-latio2n-for-photocatalytic-water-oxidation-reaction
#18
Feng-Qiang Xiong, Lipeng Wan, Yue Li, Tiju Thomas, Francis Joseph DiSalvo, Minghui Yang
LaTiO2N photocatalysts were prepared via thermal ammonalysis of flux-synthesized La2Ti2O7 and La2TiO5, and were investigated for water oxidation. Though LaTiO2N derived from La2TiO5 appears defect-free in UV-Vis-NIR and electron paramagnetic resonance spectroscopies, its performance is much lower than conventional La2Ti2O7-derived LaTiO2N with defects. It is shown by Mott-Schottky analysis that La2TiO5-derived LaTiO2N has significantly lower donor density; this can result in insufficient build-in electric field for the separation of photogenerated electrons and holes...
January 17, 2017: ChemSusChem
https://www.readbyqxmd.com/read/28093510/de-novo-formation-of-a-symptomatic-arachnoid-cyst-in-an-adult
#19
George M Ibrahim, Naif M Alotaibi, Nir Lipsman, Farshad Nassiri, Leodante da Costa
No abstract text is available yet for this article.
January 17, 2017: Neurology
https://www.readbyqxmd.com/read/28093233/changes-in-vascular-responsiveness-during-a-hyperglycemia-challenge-measured-by-near-infrared-spectroscopy-vascular-occlusion-test
#20
Rogério Nogueira Soares, Raylene A Reimer, Juan Manuel Murias
BACKGROUND: Postprandial hyperglycemia is associated with impaired vascular responsiveness. Recent studies have established the use of a near-infrared spectroscopy (NIRS)-derived approach, combined with a vascular occlusion test (VOT), to examine vascular responsiveness within the microvasculature in normoglycemia. The aim of this study was to examine whether this NIRS-VOT technique could detect differences in vascular responsiveness following a hyperglycemic challenge. METHODS AND RESULTS: Fourteen young healthy individuals participated in the study...
January 13, 2017: Microvascular Research
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