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myelomeningoceles

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https://www.readbyqxmd.com/read/27911247/correlation-of-mortality-with-lesion-level-in-patients-with-myelomeningocele-a-population-based-study
#1
Joel Haakon Borgstedt-Bakke, Morten Fenger-Grøn, Mikkel Mylius Rasmussen
OBJECTIVE The aim of this study was to assess myelomeningocele mortality, correlate these findings to lesion level, and investigate mortality evolution. METHODS From the population-based western Denmark myelomeningocele database, the authors extracted the records of 187 patients born between January 1, 1970, and July 1, 2015. Patients were categorized according to their most rostral lesion level into cervical, thoracic, lumbar, or sacral groups. Furthermore, patients were categorized based on their birth dates (1970-1979, 1980-1989, and 1990-2015)...
December 2, 2016: Journal of Neurosurgery. Pediatrics
https://www.readbyqxmd.com/read/27909623/distribution-of-interstitial-cells-of-cajal-in-the-bladders-of-fetal-rats-with-retinoic-acid-induced-myelomeningocele
#2
Ali Tekin, Osman Zeki Karakuş, Gülce Hakgüder, Oğuz Ateş, Erdener Özer, Mustafa Olguner, Feza Miraç Akgür
OBJECTIVE: Myelomeningocele (MMC) is one of the most common reason of neurogenic bladder dysfunction in children. Although neurogenic bladder dysfunction occurrence is related with bladder innervation, also there are some changes seen in the smooth muscle and neural cells of the bladder. Interstitial cells of Cajal (ICC) are the pacemaker cells found in organs with peristaltic activity. Although it has been shown that ICC are diminished in the rat urinary bladder with traumatic spinal cord injury, there is no data about ICC in fetal rat bladders with MMC...
December 2016: Turkish Journal of Urology
https://www.readbyqxmd.com/read/27902634/the-surgical-treatment-of-spinal-deformity-in-children-with-myelomeningocele-the-role-of-personalized-three-dimensional-printed-models
#3
Lawrence Karlin, Peter Weinstock, Daniel Hedequist, Sanjay P Prabhu
This study was carried out to evaluate the benefits of personalized three-dimensional printing as an aid to the performance of surgery for the correction of spinal deformity in children with myelomeningocele. We performed a retrospective review to include all such children for whom personalized three-dimensional spine models were used for surgical planning (group A) and compared them through subjective and objective criteria to a similar group that had no models (group B). The seven children in group A were younger and had more complex deformities than the 10 children in group B...
November 29, 2016: Journal of Pediatric Orthopedics. Part B
https://www.readbyqxmd.com/read/27894916/reliability-of-extended-dorsal-intercostal-artery-perforator-propeller-flaps-for-reconstruction-of-large-myelomeningocele-defects
#4
Goktekin Tenekeci, Yavuz Basterzi
Reconstruction of large myelomeningocele defects using extended (elongated beyond the lateral margin of the latissimus dorsi muscle) dorsal intercostal artery perforator (DICAP) propeller flaps is not recommended by previous studies. However, to provide tension-free and successful closure of a defect, the DICAP propeller flaps must sometimes be elongated beyond this margin. Our experience and results in this issue are discussed. In this article, reconstruction of 11 consecutive cases, with large myelomeningocele defects in which standard DICAP propeller flaps were incapable to close the defect, was achieved using extended DICAP propeller flaps between June 2013 and November 2015...
November 15, 2016: Journal of Plastic, Reconstructive & Aesthetic Surgery: JPRAS
https://www.readbyqxmd.com/read/27881182/research-prevalence-of-neural-tube-defects-khartoum-sudan-august-2014-july-2015
#5
Ilham M Omer, Osman M Abdullah, Inaam N Mohammed, Lina A Abbasher
BACKGROUND: Neural tube defects (NTDs) are birth defects that results from failure of the neural tube to develop properly during early pregnancy. METHODS: We studied the prevalence of neural tube defects in newborns admitted to the NICU in Soba University and Omdurman Maternity hospitals, during the period 1st August 2014 to 31st July 2015. A cross-sectional hospital based study, involved all newborns with any type of neural tube defect admitted to the NICU in the study area during the study period...
November 24, 2016: BMC Research Notes
https://www.readbyqxmd.com/read/27875931/early-numeracy-skills-in-preschool-aged-children-a-review-of-neurocognitive-findings-and-implications-for-assessment-and-intervention
#6
Kimberly P Raghubar, Marcia A Barnes
OBJECTIVES: The goals are to (1) provide a review of the typical and atypical development of early numeracy; (2) present what is known about the neurocognitive underpinnings of early numeracy; and (3) discuss the implications for early assessment and intervention. METHOD: Studies on the development of typical and atypical early numeracy are reviewed with a particular focus on longitudinal findings including those from our work on spina bifida myelomeningocele. Implications of this research for assessment are presented...
November 23, 2016: Clinical Neuropsychologist
https://www.readbyqxmd.com/read/27874207/congenital-high-airway-obstruction-syndrome-chaos-associated-with-cervical-myelomeningocele
#7
Mehmet Emin Adin
Congenital high airway obstruction syndrome (CHAOS) is a rare and potentially fatal entity resulting from complete or near complete developmental airway obstruction. Although most reported cases of CHAOS are sporadic, the condition may also be associated with certain syndromes and a variety of cervical masses. Meningocele and myelomeningocele have not yet been reported in association with CHAOS. We describe the typical constellation of sonographic findings in a case of early diagnosis of CHAOS associated with cervical myelomeningocele...
November 22, 2016: Journal of Clinical Ultrasound: JCU
https://www.readbyqxmd.com/read/27868580/attention-lapses-in-children-with-spina-bifida-and-hydrocephalus-and-children-with-attention-deficit-hyperactivity-disorder
#8
Gabriel G De la Torre, Alba Martin, Elizabeth Cervantes, Rocio Guil, Jose M Mestre
Attentional lapses are usually defined as temporary and often brief shifts of attention away from some primary task to unrelated internal information processing. This study addressed the incidence of attention lapses and differences in attentional functioning in 30 children with attention-deficit/hyperactivity disorder (ADHD), 26 healthy children, and 29 children with spina bifida myelomeningocele and hydrocephalus (SBH). Assessments were conducted using computerized tonic and phasic attention tests, the Symbol Digit Modalities Test (SDMT), and the Trail Making Test Form B (TMT-B)...
November 20, 2016: Journal of Clinical and Experimental Neuropsychology
https://www.readbyqxmd.com/read/27867946/advances-in-fetal-surgery
#9
REVIEW
Kathryn M Maselli, Andrea Badillo
Historically, the gold standard for the treatment of congenital malformations has been planned delivery at tertiary care center with attempted post-natal repair or amelioration of the lesion. Over the last few decades however, rapid advances in imaging and instrumentation technology combined with superior knowledge of fetal pathophysiology has led to the development of novel intrauterine interventions for most common fetal anomalies. Great success has already been seen the treatment of previous devastating anomalies such as myelomeningocele (MMC), congenital cystic malformations of the lung, twin-twin transfusion, and sacrococcygeal teratomas...
October 2016: Annals of Translational Medicine
https://www.readbyqxmd.com/read/27862250/prenatal-myelomeningocele-repair-do-bladders-better
#10
Maya Horst, Luca Mazzone, Thomas Schraner, Christine Bodmer, Ueli Möhrlen, Martin Meuli, Rita Gobet
AIMS: Prenatal myelomeningocele (MMC) repair has been proven to significantly reduce the need for hydrocephalus shunting and improve lower-extremity motor outcomes. The aim of this study was to evaluate the effect of prenatal MMC repair on the urological outcome. METHODS: All patients who underwent fetal MMC repair at our institution are followed prospectively. Assessments include medical history, renal and bladder ultrasound, voiding cystourethrogram and urodynamic study, need for clean intermittent catheterization (CIC) and anticholinergics, and the occurrence of urinary tract infections (UTI)...
November 15, 2016: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/27858385/third-ventricle-floor-variations-and-abnormalities-in-myelomeningocele-associated-hydrocephalus-an-experience-in-455-endoscopic-third-ventriculostomy-procedures
#11
Volkan Etus, Tugba Morali Guler, Hakan Karabagli
AIM: This multicenter study aims to evaluate the incidence of anatomical variations and abnormalities of the third ventricle floor encountered during endoscopic third ventriculostomy (ETV) procedure in myelomeningocele associated hydrocephalus (MAH) cases. MATERIAL AND METHODS: A retrospective analysis was performed on 455 pediatric MAH cases that have been treated with ETV. This case series consisted of the patients who were initially treated with ETV and those who were treated with ETV for the management of cerebrospinal fluid shunt dysfunction as well...
September 21, 2016: Turkish Neurosurgery
https://www.readbyqxmd.com/read/27857862/neurosurgery-concepts-key-perspectives-on-intrathecal-fluorescein-for-detecting-intraoperative-cerebrospinal-fluid-leak-during-endoscopic-endonasal-surgery-spinal-intraarterial-chemotherapy-oligoastrocytoma-classification-by-in-situ-molecular-genetics-and-prenatal
#12
https://www.readbyqxmd.com/read/27852504/bilateral-rib-based-distraction-to-the-pelvis-for-the-management-of-congenital-gibbus-deformity-in-the-growing-child-with-myelodysplasia
#13
John T Smith
BACKGROUND: Congenital gibbus deformity of the spine associated with myelodysplasia is a challenging problem in the growing child and is commonly associated with skin breakdown and chronic infection. Surgical solutions including kyphectomy, flap closure of the skin, and early spinal fusion are associated with a high rate of complications and, ultimately, a short trunk due to stoppage of spinal growth. The purpose of this article is to describe our early results in using a rib-based distraction to the pelvis without vertebral resection and fusion to manage this deformity...
January 2016: Spine Deformity
https://www.readbyqxmd.com/read/27846400/spinal-cordectomy-a-new-hope-for-morbid-spinal-conditions
#14
REVIEW
Subhas K Konar, Tanmoy K Maiti, Shyamal C Bir, Anil Nanda
A spinal cordectomy is a treatment option for several disorders of the spinal cord like post-traumatic syringomyelia, spinal cord tumor and myelomeningocele. We have done a systematic analysis of all reported cases of spinal cordectomy to investigate the possible outcomes and complications. A PubMed search was performed for literature published from 1949 to 2015 with search words "spinal cordectomy", "spinal cord transection" and "cordectomy for malignant spinal cord tumors" to select articles containing information about the indication, outcome and complication of spinal cordectomy performed for diverse etiologies...
November 10, 2016: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/27830929/fetal-surgery-for-myelomeningocele-a-review-of-current-clinical-practice-and-translational-research
#15
Sandra K Kabagambe, Yue J Chen, Diana L Farmer
INTRODUCTION: The Management of Myelomeningocele Study (MOMS) showed that prenatal repair of myelomeningocele (MMC) resulted in better neurological outcomes than postnatal closure but was, by necessity, associated with higher rates of obstetrical complications. Fetoscopic MMC repair has been explored as an alternative to reduce complications of the open approach used in MOMS. This review summarizes the trends in fetoscopic and open fetal repair of MMC. EVIDENCE ACQUISITION: We searched PubMed and Embase® for studies on fetal repair of MMC published since the completion of the MOMS trial...
November 10, 2016: Minerva Pediatrica
https://www.readbyqxmd.com/read/27830629/independence-in-self-care-activities-in-children-with-myelomeningocele-exploring-factors-based-on-the-international-classification-of-function-model
#16
Shoshana Steinhart, Emmanuel Kornitzer, Adi Bracha Baron, Coos Wever, Levana Shoshan, Michal Katz-Leurer
PURPOSE: To investigate the relationship between disease factors, body functions and structures, activities, personal and environmental factors with independence in self-care activities in children with myelomeningocele (MMC), utilizing the International Classification of Function model. METHOD: 113 children with MMC, aged 3-18 years were assessed during an annual MMC-clinic visit. Data on the personal and environmental factors, disease factors, hand function, mobility, visual perception, cognition, and communication were assessed in relation to the Pediatric Evaluation of Disability Inventory (PEDI) self-care domain...
November 10, 2016: Disability and Rehabilitation
https://www.readbyqxmd.com/read/27822764/hemimetameric-shift-in-spina-bifida-three-case-reports
#17
Huseyin Canaz, Gokhan Canaz, Bekir Yavuz Ucar, Ibrahim Alatas
PURPOSE: Hemivertebrae is the most frequent reason of congenital scoliosis, and hemimetameric shift is a finding, which is characterized by two hemivertebraes located contralateral, with at least one normal vertebra between them. Embryologically, hemivertebrae is caused by delay in somite movements and as a result, a total vertebral shift occurs because of mismatches in the following segments. Hemimetameric shift accompanying spina bifida is described as extremely rare. There are only two case series of hemimetameric shift in literature but no spina bifida patient was reported in these series...
November 7, 2016: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
https://www.readbyqxmd.com/read/27798984/rate-of-shunt-revision-as-a-function-of-age-in-patients-with-shunted-hydrocephalus-due-to-myelomeningocele
#18
Esther B Dupepe, Betsy Hopson, James M Johnston, Curtis J Rozzelle, W Jerry Oakes, Jeffrey P Blount, Brandon G Rocque
OBJECTIVE It is generally accepted that cerebrospinal fluid shunts fail most frequently in the first years of life. The purpose of this study was to describe the risk of shunt failure for a given patient age in a well-defined cohort with shunted hydrocephalus due to myelomeningocele (MMC). METHODS The authors analyzed data from their institutional spina bifida research database including all patients with MMC and shunted hydrocephalus. For the entire population, the number of shunt revisions in each year of life was determined...
November 2016: Neurosurgical Focus
https://www.readbyqxmd.com/read/27781020/stem-cells-in-functional-bladder-engineering
#19
REVIEW
Jakub Smolar, Souzan Salemi, Maya Horst, Tullio Sulser, Daniel Eberli
Conditions impairing bladder function in children and adults, such as myelomeningocele, posterior urethral valves, bladder exstrophy or spinal cord injury, often need urinary diversion or augmentation cystoplasty as when untreated they may cause severe bladder dysfunction and kidney failure. Currently, the gold standard therapy of end-stage bladder disease refractory to conservative management is enterocystoplasty, a surgical enlargement of the bladder with intestinal tissue. Despite providing functional improvement, enterocystoplasty is associated with significant long-term complications, such as recurrent urinary tract infections, metabolic abnormalities, stone formation, and malignancies...
September 2016: Transfusion Medicine and Hemotherapy
https://www.readbyqxmd.com/read/27775158/factors-influencing-the-use-of-intermittent-bladder-catheterization-by-individuals-with-spina-bifida-in-brazil-and-germany
#20
Fabiana Faleiros, Giovana Pelosi, Seth Warschausky, Denise Tate, Christoph Käppler, Elisabeth Thomas
PURPOSE: Intermittent catheterization (IC) often is essential for individuals with spina bifida/myelomeningocele (SBM) and neurogenic bladder. This study aimed to identify and analyze the factors that influence the use of IC. DESIGN AND METHODS: Descriptive study with convenience sampling. Data were collected using printed (Brazil) and online (Germany) questionnaires, and analyzed using multivariate logistical regression and analysis of variance. The study included 100 Brazilian and 100 German patients, aged 0-55 years, with SBM who utilized IC...
October 24, 2016: Rehabilitation Nursing: the Official Journal of the Association of Rehabilitation Nurses
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