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myelomeningoceles

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https://www.readbyqxmd.com/read/28099558/the-mortality-rate-after-hospital-discharge-in-patients-with-myelomeningocele-decreased-after-implementation-of-mandatory-flour-fortification-with-folic-acid
#1
Renato Manganelli Salomão, Tatiana Protzenko Cervante, José Francisco Manganelli Salomão, Soniza Vieira Alves Leon
Objective: To evaluate the mandatory folic acid fortification of flour on mortality rates after the hospital discharge of children born with myelomeningocele, the most affected age group and the most frequent cause of death. Methods: A retrospective study of 383 children born with myelomeningocele from January 1990 to December 2013 in a high-fetal-risk reference hospital. Results: A total of 39 patients died (10.1%),of which 23 (6%) died after discharge...
January 2017: Arquivos de Neuro-psiquiatria
https://www.readbyqxmd.com/read/28058487/fetal-surgery-a-critical-review
#2
REVIEW
H Kitagawa, K C Pringle
Therapeutic fetal surgical procedures are predicated upon the ability to make an accurate fetal diagnosis. The earliest open fetal surgical procedures were introduced in the 1960s to treat Rh isoimmunisation. They were introduced when it became possible to predict impending fetal demise. Open procedures were abandoned when percutaneous approaches proved superior. The introduction of fetal ultrasound allowed the diagnosis of other congenital anomalies, some being amenable to fetal interventions. Open fetal surgical procedures were initially utilised, with significant maternal morbidity...
January 5, 2017: Pediatric Surgery International
https://www.readbyqxmd.com/read/28058485/the-current-profile-of-persistent-cloaca-and-cloacal-exstrophy-in-japan-the-results-of-a-nationwide-survey-in-2014-and-a-review-of-the-literature
#3
Masayuki Kubota
PURPOSE: The current profile of persistent cloaca (PC) and cloacal exstrophy (CE) in Japan was first examined in 2014. MATERIALS AND METHODS: Information was obtained by sending a questionnaire to 244 university hospitals and children's hospitals. RESULTS: Responses from 113 institutions reported 466 PC cases and 229 CE cases. The incidences of PC and CE from 1980 to 2012 were 0.97 and 0.49 per 100,000 live births, respectively. In the previous 5 years, antenatal abnormalities were found in 57...
January 5, 2017: Pediatric Surgery International
https://www.readbyqxmd.com/read/28043315/right-sided-congenital-diaphragmatic-hernia-and-myelomeningocele-a-rare-association
#4
Syed Rehan Ali, Shakeel Ahmed
Congenital diaphragmatic hernia (CDH) is a rare birth defect with a prevalence of < 0.5 per 1,000 live births. Majority of these defects are left-sided as most studies suggest that frequency of right-sided CDH was 10% of the total. The association of CDH with myelomeningocele (MMC) is extremely rare; as in Sweed's study of 116 consecutive cases of CDH, the incidence of associated MMC with CDH was stated as 4.3%. There has been one previous case report of leftsided CDH, MMC and hydrocephalus prenatally diagnosed; but to the best of authors' knowledge, this is the first reported case of the above constellation with a right-sided CDH diagnosed prenatally...
December 2016: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
https://www.readbyqxmd.com/read/28028598/a-comparison-of-the-moms-trial-results-to-a-contemporaneous-single-institution-postnatal-closure-cohort
#5
Nicholas M B Laskay, Anastasia A Arynchyna, Samuel G McClugage, Betsy Hopson, Chevis Shannon, Benjamin Ditty, John C Wellons, Jeffrey P Blount, Brandon G Rocque
PURPOSE: We evaluate a single-institution cohort of mothers contemporaneous with the Management of Myelomeningocele Study (MOMS) trial to determine the generalizability of MOMS results and compare shunt rates. METHODS: A retrospective chart review identified patients with myelomeningocele born between 2003 and 2009. We applied MOMS eligibility criteria and compared sociodemographic variables between patients at our institution who would have been eligible or ineligible and MOMS participants...
December 27, 2016: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
https://www.readbyqxmd.com/read/28005733/an-ideal-flap-alternative-for-closure-of-myelomeningocele-defects-dorsal-intercostal-artery-perforator-flap
#6
Omer Faruk Kocak, Canser Yilmaz Demir
BACKGROUND: Dorsal intercostal artery perforator (DICAP) flap is an ideal flap to be used for posterior trunk defects since it leads to lower donor-site morbidity and shorter operative times, offers easy surgical planning, and uses a reliable and easily identifiable artery. MATERIALS AND METHODS: The study retrospectively reviewed 52 patients with meningomyelocele defects that were closed with DICAP flap between January 2007 and May 2015. SURGICAL TECHNIQUE: Each of the 4th to 12th posterior intercostal arteries can be used as dorsal perforators...
November 2016: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/27997256/ultrasound-functional-evaluation-of-fetuses-with-myelomeningocele-study-of-the-interpretation-of-results
#7
A Maroto, T Illescas, M Meléndez, S Arévalo, C Rodó, J L Peiró, M Belfort, A Cuxart, E Carreras
OBJECTIVE: To assess the reliability of the interpretation of a new technique for the ultrasound evaluation of the level of neurological lesion in fetuses with myelomeningocele. METHODS: Observational study including myelomeningocele fetuses, referred to our center for the sonographic assessment of the fetal lower-limb movements, made and recorded by an expert in Maternal-fetal medicine and a specialist in Rehabilitation. Two observers, with different levels of expertise and blinded to each other's results, interpreted each recorded scan two different times...
December 20, 2016: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/27988193/a-4-year-prospective-urological-assessment-of-in-utero-myelomeningocele-repair-does-gestational-age-at-birth-play-a-role-at-later-neurogenic-bladder-pattern
#8
Marcela Leal da Cruz, Riberto Liguori, Gilmar Garrone, Sérgio Leite Ottoni, Sérgio Cavalheiro, Antonio Fernandes Moron, Antonio Macedo
PURPOSE: A major complication of in utero myelomeningocele (MMC) repair is premature delivery. The prematurity rate in MOMS study was 79%, with a mean gestational age (GA) at birth of 34 weeks. Considering this particular aspect of prenatal surgery group, we speculated if prematurity could also influence the urological outcome. MATERIAL AND METHODS: Since November 2011, we prospectively followed a population of MMC patients that had undergone in utero repair. RESULTS: We compared this population according to GA at birth: below 34 weeks (group 1) and 34 weeks or above (group 2)...
December 14, 2016: Journal of Urology
https://www.readbyqxmd.com/read/27940761/tetanus-and-occam-s-razor-almost-forgotten-but-not-gone-a-case-report
#9
Stephanie O Skuby, Eunice Rhee, Elizabeth H Thilo, Eric A F Simões
Tetanus is a rare disease in industrialized countries, largely due to the highly protective effect of immunization. We present a case of tetanus in a formerly preterm infant with myelomeningocele repaired in utero, who presented at 44 days of age with poor feeding, lethargy, and increased tone. His symptoms progressed despite a course of antibiotics for presumed meningitis. At 73 days of age (on 29th day of hospitalization), a clinical diagnosis of tetanus was made based on the presence of risus sardonicus, trismus, and generalized hypertonicity...
November 2016: Pediatrics
https://www.readbyqxmd.com/read/27927508/kyphectomy-in-children-with-severe-myelomeningocele-related-kyphosis
#10
R N Dunn, L N Bomela
STUDY DESIGN: Retrospective review of prospectively maintained database. OBJECTIVES: To review myelomeningocele patients with severe kyphosis undergoing kyphectomy surgery in terms of complications and clinical and radiographic outcomes. SUMMARY OF BACKGROUND DATA: Because of posterior element abnormality in myelomeningocele, the extensor muscles act as perverted flexors, driving progressive kyphosis that resulted in sitting, respiratory, and skin breakdown problems...
May 2016: Spine Deformity
https://www.readbyqxmd.com/read/27911247/correlation-of-mortality-with-lesion-level-in-patients-with-myelomeningocele-a-population-based-study
#11
Joel Haakon Borgstedt-Bakke, Morten Fenger-Grøn, Mikkel Mylius Rasmussen
OBJECTIVE The aim of this study was to assess myelomeningocele mortality, correlate these findings to lesion level, and investigate mortality evolution. METHODS From the population-based western Denmark myelomeningocele database, the authors extracted the records of 187 patients born between January 1, 1970, and July 1, 2015. Patients were categorized according to their most rostral lesion level into cervical, thoracic, lumbar, or sacral groups. Furthermore, patients were categorized based on their birth dates (1970-1979, 1980-1989, and 1990-2015)...
December 2, 2016: Journal of Neurosurgery. Pediatrics
https://www.readbyqxmd.com/read/27909623/distribution-of-interstitial-cells-of-cajal-in-the-bladders-of-fetal-rats-with-retinoic-acid-induced-myelomeningocele
#12
Ali Tekin, Osman Zeki Karakuş, Gülce Hakgüder, Oğuz Ateş, Erdener Özer, Mustafa Olguner, Feza Miraç Akgür
OBJECTIVE: Myelomeningocele (MMC) is one of the most common reason of neurogenic bladder dysfunction in children. Although neurogenic bladder dysfunction occurrence is related with bladder innervation, also there are some changes seen in the smooth muscle and neural cells of the bladder. Interstitial cells of Cajal (ICC) are the pacemaker cells found in organs with peristaltic activity. Although it has been shown that ICC are diminished in the rat urinary bladder with traumatic spinal cord injury, there is no data about ICC in fetal rat bladders with MMC...
December 2016: Turkish Journal of Urology
https://www.readbyqxmd.com/read/27902634/the-surgical-treatment-of-spinal-deformity-in-children-with-myelomeningocele-the-role-of-personalized-three-dimensional-printed-models
#13
Lawrence Karlin, Peter Weinstock, Daniel Hedequist, Sanjay P Prabhu
This study was carried out to evaluate the benefits of personalized three-dimensional printing as an aid to the performance of surgery for the correction of spinal deformity in children with myelomeningocele. We performed a retrospective review to include all such children for whom personalized three-dimensional spine models were used for surgical planning (group A) and compared them through subjective and objective criteria to a similar group that had no models (group B). The seven children in group A were younger and had more complex deformities than the 10 children in group B...
December 6, 2016: Journal of Pediatric Orthopedics. Part B
https://www.readbyqxmd.com/read/27894916/reliability-of-extended-dorsal-intercostal-artery-perforator-propeller-flaps-for-reconstruction-of-large-myelomeningocele-defects
#14
Goktekin Tenekeci, Yavuz Basterzi
Reconstruction of large myelomeningocele defects using extended (elongated beyond the lateral margin of the latissimus dorsi muscle) dorsal intercostal artery perforator (DICAP) propeller flaps is not recommended by previous studies. However, to provide tension-free and successful closure of a defect, the DICAP propeller flaps must sometimes be elongated beyond this margin. Our experience and results in this issue are discussed. In this article, reconstruction of 11 consecutive cases, with large myelomeningocele defects in which standard DICAP propeller flaps were incapable to close the defect, was achieved using extended DICAP propeller flaps between June 2013 and November 2015...
January 2017: Journal of Plastic, Reconstructive & Aesthetic Surgery: JPRAS
https://www.readbyqxmd.com/read/27881182/research-prevalence-of-neural-tube-defects-khartoum-sudan-august-2014-july-2015
#15
Ilham M Omer, Osman M Abdullah, Inaam N Mohammed, Lina A Abbasher
BACKGROUND: Neural tube defects (NTDs) are birth defects that results from failure of the neural tube to develop properly during early pregnancy. METHODS: We studied the prevalence of neural tube defects in newborns admitted to the NICU in Soba University and Omdurman Maternity hospitals, during the period 1st August 2014 to 31st July 2015. A cross-sectional hospital based study, involved all newborns with any type of neural tube defect admitted to the NICU in the study area during the study period...
November 24, 2016: BMC Research Notes
https://www.readbyqxmd.com/read/27875931/early-numeracy-skills-in-preschool-aged-children-a-review-of-neurocognitive-findings-and-implications-for-assessment-and-intervention
#16
Kimberly P Raghubar, Marcia A Barnes
OBJECTIVES: The goals are to (1) provide a review of the typical and atypical development of early numeracy; (2) present what is known about the neurocognitive underpinnings of early numeracy; and (3) discuss the implications for early assessment and intervention. METHOD: Studies on the development of typical and atypical early numeracy are reviewed with a particular focus on longitudinal findings including those from our work on spina bifida myelomeningocele. Implications of this research for assessment are presented...
November 23, 2016: Clinical Neuropsychologist
https://www.readbyqxmd.com/read/27874207/congenital-high-airway-obstruction-syndrome-chaos-associated-with-cervical-myelomeningocele
#17
Mehmet Emin Adin
Congenital high airway obstruction syndrome (CHAOS) is a rare and potentially fatal entity resulting from complete or near complete developmental airway obstruction. Although most reported cases of CHAOS are sporadic, the condition may also be associated with certain syndromes and a variety of cervical masses. Meningocele and myelomeningocele have not yet been reported in association with CHAOS. We describe the typical constellation of sonographic findings in a case of early diagnosis of CHAOS associated with cervical myelomeningocele...
November 22, 2016: Journal of Clinical Ultrasound: JCU
https://www.readbyqxmd.com/read/27868580/attention-lapses-in-children-with-spina-bifida-and-hydrocephalus-and-children-with-attention-deficit-hyperactivity-disorder
#18
Gabriel G De la Torre, Alba Martin, Elizabeth Cervantes, Rocio Guil, Jose M Mestre
Attentional lapses are usually defined as temporary and often brief shifts of attention away from some primary task to unrelated internal information processing. This study addressed the incidence of attention lapses and differences in attentional functioning in 30 children with attention-deficit/hyperactivity disorder (ADHD), 26 healthy children, and 29 children with spina bifida myelomeningocele and hydrocephalus (SBH). Assessments were conducted using computerized tonic and phasic attention tests, the Symbol Digit Modalities Test (SDMT), and the Trail Making Test Form B (TMT-B)...
November 20, 2016: Journal of Clinical and Experimental Neuropsychology
https://www.readbyqxmd.com/read/27867946/advances-in-fetal-surgery
#19
REVIEW
Kathryn M Maselli, Andrea Badillo
Historically, the gold standard for the treatment of congenital malformations has been planned delivery at tertiary care center with attempted post-natal repair or amelioration of the lesion. Over the last few decades however, rapid advances in imaging and instrumentation technology combined with superior knowledge of fetal pathophysiology has led to the development of novel intrauterine interventions for most common fetal anomalies. Great success has already been seen the treatment of previous devastating anomalies such as myelomeningocele (MMC), congenital cystic malformations of the lung, twin-twin transfusion, and sacrococcygeal teratomas...
October 2016: Annals of Translational Medicine
https://www.readbyqxmd.com/read/27862250/prenatal-myelomeningocele-repair-do-bladders-better
#20
Maya Horst, Luca Mazzone, Thomas Schraner, Christine Bodmer, Ueli Möhrlen, Martin Meuli, Rita Gobet
AIMS: Prenatal myelomeningocele (MMC) repair has been proven to significantly reduce the need for hydrocephalus shunting and improve lower-extremity motor outcomes. The aim of this study was to evaluate the effect of prenatal MMC repair on the urological outcome. METHODS: All patients who underwent fetal MMC repair at our institution are followed prospectively. Assessments include medical history, renal and bladder ultrasound, voiding cystourethrogram and urodynamic study, need for clean intermittent catheterization (CIC) and anticholinergics, and the occurrence of urinary tract infections (UTI)...
November 15, 2016: Neurourology and Urodynamics
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