Read by QxMD icon Read

Metastic niche

Theodoros Goulas, Miroslaw Ksiazek, Irene Garcia-Ferrer, Alicja M Sochaj-Gregorczyk, Irena Waligorska, Marcin Wasylewski, Jan Potempa, F Xavier Gomis-Rüth
Enduring host-microbiome relationships are based on adaptive strategies within a particular ecological niche. Tannerella forsythia is a dysbiotic member of the human oral microbiome that inhabits periodontal pockets and contributes to chronic periodontitis. To counteract endopeptidases from the host or microbial competitors, T. forsythia possesses a serpin-type proteinase inhibitor called miropin. Although serpins from animals, plants, and viruses have been widely studied, those from prokaryotes have received only limited attention...
June 30, 2017: Journal of Biological Chemistry
Taehun Lee, Yonghyuk Lee, Kisung Kang, Aloysius Soon
Growing ultrathin oxide layers on metal surfaces presents a new class of low-dimensional nanomaterials with exceptional chemical and physical properties. These "new oxides" can be used in many niche technologies and applications such as nanoscale electronics and heterogeneous nanocatalysis. In this work, we study the formation of surface oxidic structures and motifs of Cu, supported on the Au(111) substrate, using first-principles density-functional theory calculations in conjunction with an ab initio atomistic thermodynamics model...
March 14, 2016: Physical Chemistry Chemical Physics: PCCP
Dobromir G Dotov
Radical embodied cognitive neuroscience (RECN) will probably rely on dynamical systems theory (DST) and complex systems theory for methods and formalism. Yet, there have been plenty of non-radical neurodynamicists out there for quite some time. How much of their work fits with radical embodied cognitive science, what do they need RECN for, and what are the inconsistencies between RECN and established neurodynamics that would have to be resolved? This paper is both theoretical hypothesis and review. First, it provides a brief overview of the typical, purely structural considerations why the central nervous systems (CNS) should be treated as a nonlinear dynamical system and what this entails...
2014: Frontiers in Human Neuroscience
Jelle Bruineberg, Erik Rietveld
In this paper, we set out to develop a theoretical and conceptual framework for the new field of Radical Embodied Cognitive Neuroscience. This framework should be able to integrate insights from several relevant disciplines: theory on embodied cognition, ecological psychology, phenomenology, dynamical systems theory, and neurodynamics. We suggest that the main task of Radical Embodied Cognitive Neuroscience is to investigate the phenomenon of skilled intentionality from the perspective of the self-organization of the brain-body-environment system, while doing justice to the phenomenology of skilled action...
2014: Frontiers in Human Neuroscience
Mario J Matteo, Rita I Armitano, Mariela Romeo, Andres Wonaga, Martín Olmos, Mariana Catalano
Helicobacter pylori BabA adhesin metastability could yield variants with potential for periodic activation and deactivation of their mediated adherence. babA/B or babB/A chimeras could play an important role in translational regulation. We investigated the frequency of different bab gene profiles in paired isolates from antrum and corpus recovered from patients with chronic gastritis. Isolates from 174 biopsies from 34 patients were included, and bab genes at the three common chromosomal loci were investigated...
August 30, 2011: International Journal of Molecular Epidemiology and Genetics
Guillaume Blin, Nassrine Lablack, Marianne Louis-Tisserand, Claire Nicolas, Catherine Picart, Michel Pucéat
Embryonic stem cells (ESC) are pluripotent cells capable to give rise to any embryonic cell lineage. In culture, these cells form colonies creating their own niche. Depending upon the molecular and physico-chemical environment, the pluripotent cells oscillate between two metastable states of pluripotency either reminiscent of the inner cell mass of the embryo or the epiblast, a stage of development which give rise to the three embryonic layers, ectoderm, endoderm and mesoderm. Herein, we used PLL/HA nanofilms cross-linked to various degrees to modulate the nanoenvironment of ESCs...
March 2010: Biomaterials
Thomas Graf, Matthias Stadtfeld
New studies suggest that stem cells of embryonic, neural, and hematopoietic origin are heterogeneous, with cells moving between two or more metastable states. These cell states show a bias in their differentiation potential and correlate with specific patterns of transcription factor expression and chromatin modifications.
November 6, 2008: Cell Stem Cell
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"