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Intraparenchymal hemorrhage

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https://www.readbyqxmd.com/read/27915393/role-of-prothrombin-complex-concentrate-pcc-in-acute-intracerebral-hemorrhage-with-positive-cta-spot-sign-an-institutional-experience-at-a-regional-and-state-designated-stroke-center
#1
Razia Rehmani, Angela Han, Jawaad Hassan, Jeffrey Farkas
PURPOSE: Our objective is to identify the effect of prothrombin complex concentrate (PCC) in acute intracranial hemorrhage (ICH) by evaluating intraparenchymal hematoma expansion between initial and follow-up head CT at 5-24 h, in those with positive CTA spot sign (CTASS). CTASS is an independent predictor of hematoma growth (1). Acute ICH, regardless of etiology, can present with quick mental status decline often resulting in irreversible brain damage. Hematoma expansion appears to be a modifiable predictor of clinical outcome and an appropriate target for medical therapy...
December 3, 2016: Emergency Radiology
https://www.readbyqxmd.com/read/27894886/utility-of-urgent-computed-tomography-angiography-in-the-setting-of-intraparenchymal-brain-hemorrhage
#2
Omran Kaskar, Larry B Goldstein
BACKGROUND AND PURPOSE: Patients presenting with an intracerebral hemorrhage (ICH) generally have an initial noncontrast computed tomography (NCCT) of the brain. Computed tomography angiography (CTA) can help identify secondary causes of ICH and detect a "spot sign." We hypothesized that performing an urgent CTA in the setting of a presumed primary ICH has only limited utility and did not alter urgent management. METHODS: This was a retrospective study of consecutive patients presenting with a primary ICH identified from the Duke University Stroke Registry from 2010 to 2013 who had an ICH detected on an initial NCCT...
November 25, 2016: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/27861331/intraparenchymal-endodermal-cyst-with-spontaneous-intracystic-hemorrhage-in-the-temporal-lobe-of-an-adult
#3
Xin-Jie Bao, Xue-Yuan Li, Qi-Pu Wang, Xin-Yu Ren, Zhi-Yong Liang, Wen-Bin Ma, Ren-Zhi Wang, Jun-Ji Wei
BACKGROUND: Endodermal cysts (EC) are rare but well-known congenial lesions of the central nervous system mainly located in the spinal subdural space. Intracranial ECs are rare and commonly encountered in the posterior cranial fossa as extra-axial lesions; an intraparenchymal location is exceedingly rare. A complete removal is the best surgical strategy and any residue can cause recurrence. It is necessary to exclude EC in patients with intracranial cystic lesions. We present a case of intraparenchymal EC with spontaneous intracystic hemorrhage in the temporal lobe of an adult...
November 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27805421/isolated-intraventricular-hemorrhage-in-adults
#4
Isabelle Barnaure, Alfonso C Liberato, R Gilberto Gonzalez, Javier M Romero
While intraventricular hemorrhage (IVH) is frequently found in association with intraparenchymal or subarachnoid hemorrhage, isolated IVH is rare in adults and seldom described. Awareness of possible causes is important in order to guide patient management. After elimination of a traumatic cause, numerous etiologies remain possible. The most frequently found underlying lesions are AVMs and aneurysms, but other vascular causes should also be sought, including cavernous malformations and moyamoya disease. Arterial hypertension, anticoagulant use, coagulopathies and certain toxic substances are also associated with isolated IVH...
November 2, 2016: British Journal of Radiology
https://www.readbyqxmd.com/read/27776795/early-plasma-transfusion-is-associated-with-improved-survival-after-isolated-traumatic-brain-injury-in-patients-with-multifocal-intracranial-hemorrhage
#5
Ronald Chang, Lindley E Folkerson, Duncan Sloan, Jeffrey S Tomasek, Ryan S Kitagawa, H Alex Choi, Charles E Wade, John B Holcomb
BACKGROUND: Plasma-based resuscitation improves outcomes in trauma patients with hemorrhagic shock, while large-animal and limited clinical data suggest that it also improves outcomes and is neuroprotective in the setting of combined hemorrhage and traumatic brain injury. However, the choice of initial resuscitation fluid, including the role of plasma, is unclear for patients after isolated traumatic brain injury. METHODS: We reviewed adult trauma patients admitted from January 2011 to July 2015 with isolated traumatic brain injury...
October 13, 2016: Surgery
https://www.readbyqxmd.com/read/27739945/blunt-prenatal-trauma-resulting-in-fetal-epidural-or-subdural-hematoma-case-report-and-systematic-review-of-the-literature
#6
Jacob R Joseph, Brandon W Smith, Hugh J L Garton
Blunt prenatal trauma is known to have consequences to the developing brain, and can result in subdural hematoma (SDH) or epidural hematoma (EDH). The authors present a case of blunt prenatal trauma resulting in a fetal SDH, intraparenchymal hematoma, and intraventricular hemorrhage, and perform a systematic review of the literature. This systematic review was conducted according to the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines. Relevant studies (up to April 2016) that reported on cases of fetal SDH or EDH after blunt prenatal trauma were identified from the PubMed database...
October 14, 2016: Journal of Neurosurgery. Pediatrics
https://www.readbyqxmd.com/read/27703060/quantitative-assessment-of-parent-vessel-and-distal-intracranial-hemodynamics-following-pipeline-flow-diversion
#7
Sophia F Shakur, Victor A Aletich, Sepideh Amin-Hanjani, Ahmed E Hussein, Fady T Charbel, Ali Alaraj
BACKGROUND: Pipeline embolization devices (PEDs) are commonly used for endovascular treatment of cerebral aneurysms but can be associated with delayed ipsilateral intraparenchymal hemorrhage. Although intra-aneurysmal hemodynamic changes have been studied, parent vessel and intracranial hemodynamics after PED use are unknown. We examine the impact of flow diversion on parent artery and distal intracranial hemodynamics. METHOD: Patients with internal carotid cerebral aneurysms treated with PED who had flow volume rate, flow velocities, pulsatility index, resistance index, Lindegaard ratio, and wall shear stress (WSS) obtained after treatment using quantitative magnetic resonance angiography were reviewed...
October 4, 2016: Interventional Neuroradiology
https://www.readbyqxmd.com/read/27686339/a-new-approach-to-selective-brain-cooling-by-a-ranque-hilsch-vortex-tube
#8
Mohammad Fazel Bakhsheshi, Yong Wang, Lynn Keenliside, Ting-Yim Lee
BACKGROUND: Target temperature management is the single most effective intervention and the gold standard in post-resuscitation care today. However, cooling the whole body below 33-34 °C can cause severe complications. Therefore, developing a selective brain cooling (SBC) approach which can be initiated early to induce rapid cooling and maintain the target temperature over 12-24 h before slowly rewarming brain temperature by itself alone would be advantageous. Vortex tubes are simple mechanical devices generating cold air from a stream of compressed air without applied chemical or energy...
December 2016: Intensive Care Medicine Experimental
https://www.readbyqxmd.com/read/27637922/intraparenchymal-hyperattenuations-on-flat-panel-ct-directly-after-mechanical-thrombectomy-are-restricted-to-the-initial-infarct-core-on-diffusion-weighted-imaging
#9
Tanja Schneider, Tobias Mahraun, Julian Schroeder, Andreas Frölich, Philip Hoelter, Marlies Wagner, Jean Darcourt, Christophe Cognard, Alain Bonafé, Jens Fiehler, Susanne Siemonsen, Jan-Hendrik Buhk
PURPOSE: The presence of intraparenchymal hyperattenuations (IPH) on flat-panel computed tomography (FP-CT) after endovascular recanalization in stroke patients is a common phenomenon. They are thought to occur in ischemic areas with breakdown of the blood-brain barrier but previous studies that investigated a mutual interaction are scarce. We aimed to assess the relationship of IPH localization with prethrombectomy diffusion-weighted imaging (DWI) lesions. METHODS: This retrospective multicenter study included 27 acute stroke patients who underwent DWI prior to FP-CT following mechanical thrombectomy...
September 16, 2016: Clinical Neuroradiology
https://www.readbyqxmd.com/read/27613246/developmental-venous-anomaly-presenting-as-a-spontaneous-intraparenchymal-hematoma-without-thrombosis
#10
Nitin Agarwal, Giulio Zuccoli, Geoffrey Murdoch, Brian T Jankowitz, Stephanie Greene
INTRODUCTION: Developmental venous anomalies (DVAs) are cited as the most common cerebral vascular malformations. Still, intracerebral hematomas are rarely thought to be caused by DVAs. In this report, the authors present a unique case of a DVA that hemorrhaged spontaneously, rather than hemorrhaging into a venous infarction following DVA thrombosis as has been more commonly reported. CLINICAL PRESENTATION: A 22-year-old previously healthy male presented to the emergency department with a severe headache, confusion, and progressive hemiparesis...
September 9, 2016: Neuroradiology Journal
https://www.readbyqxmd.com/read/27611897/surgical-outcomes-of-majewski-osteodysplastic-primordial-dwarfism-type-ii-with-intracranial-vascular-anomalies
#11
Mario Teo, Jeremiah N Johnson, Teresa E Bell-Stephens, Michael P Marks, Huy M Do, Robert L Dodd, Michael B Bober, Gary K Steinberg
OBJECTIVE Majewski osteodysplastic primordial dwarfism Type II (MOPD II) is a rare genetic disorder. Features of it include extremely small stature, severe microcephaly, and normal or near-normal intelligence. Previous studies have found that more than 50% of patients with MOPD II have intracranial vascular anomalies, but few successful surgical revascularization or aneurysm-clipping cases have been reported because of the diminutive arteries and narrow surgical corridors in these patients. Here, the authors report on a large series of patients with MOPD II who underwent surgery for an intracranial vascular anomaly...
December 2016: Journal of Neurosurgery. Pediatrics
https://www.readbyqxmd.com/read/27583173/pure-tentorial-subdural-hematoma-from-rupture-of-aneurysm-along-the-transmastoid-branches-of-the-occipital-artery
#12
Ha Son Nguyen, Ninh Doan, Saman Shabani, Michael Gelsomino, Osama Zaidat
BACKGROUND: Pure subdural hematoma (without subarachnoid, intraventricular, or intraparenchymal hemorrhage) due to a ruptured intracranial aneurysm is rare. Most reported cases involve an aneurysm along the internal carotid artery, posterior communicating artery, or middle cerebral artery. No reports have described an aneurysm along the transmastoid branches of the occipital artery. CASE DESCRIPTION: A 70-year-old female presented with sudden-onset, excruciating headaches, associated with dizziness, nausea, and emesis...
2016: Surgical Neurology International
https://www.readbyqxmd.com/read/27535634/cranial-pilocytic-astrocytoma-with-spinal-drop-metastasis-in-an-adult-case-report-and-literature-review
#13
Aasheen Munshey, Justin Moore, Catriona Maclean, Anthony Longano, Tony Goldschlager
BACKGROUND: Pilocytic astrocytoma (PA) is a benign neoplasm that typically occurs in the brain within the pediatric and adolescent age groups and is uncommon in adults. It rarely occurs within the ventricles and the overall prognosis is favourable. A pilocytic astrocytoma of the brain with spinal metastasis at presentation has never been reported in an adult. CASE DESCRIPTION: We report a case of a 47-year-old male presenting with sudden onset frontal headache associated with nausea and lethargy...
August 12, 2016: World Neurosurgery
https://www.readbyqxmd.com/read/27485455/clinical-characteristics-and-risk-factors-of-intracranial-hemorrhage-in-patients-following-allogeneic-hematopoietic-stem-cell-transplantation
#14
Xiao-Hui Zhang, Qian-Ming Wang, Huan Chen, Yu-Hong Chen, Wei Han, Feng-Rong Wang, Jing-Zhi Wang, Yuan-Yuan Zhang, Xiao-Dong Mo, Yao Chen, Yu Wang, Ying-Jun Chang, Lan-Ping Xu, Kai-Yan Liu, Xiao-Jun Huang
Intracranial hemorrhage (ICH) is one of the most life-threatening neurological complications after allogeneic hematopoietic stem cell transplantation. Although cerebral complications and its causes after allo-HSCT are well documented, assessment of the incidence and risk factors of intracranial hemorrhage following allo-HSCT are less discussed. A nested case-control study was conducted involving 160 subjects drawn from 2169 subjects who underwent HSCT at Peking University People's Hospital between 2004 and 2014...
October 2016: Annals of Hematology
https://www.readbyqxmd.com/read/27476630/intracerebral-hemorrhage-with-a-favorable-outcome-in-a-patient-with-childhood-primary-angiitis-of-the-central-nervous-system
#15
Marco Felipe Silva, Ana Raquel Feitosa, José A Paz, Nádia Emi Aikawa, Clovis A Silva
Childhood primary angiitis of the central nervous system (cPACNS) is a rare inflammatory brain disease of unknown etiology. Of note, brain hemorrhage has been rarely reported in cPACNS patients, generally associated with a delayed clinical diagnosis, or with a diagnosis only at necropsy. We present the case of a boy with cPACNS that previously suffered an ischemic stroke. At the age of 7 years and 10 months, he presented a sudden and severe headache, vomiting and reduction in consciousness level (Glasgow coma scale 7), requiring prompt tracheal intubation...
July 2016: Revista Brasileira de Reumatologia
https://www.readbyqxmd.com/read/27468510/-hypothermia-influences-on-oxygen-tension-in-the-brain-parenchyma-in-patients-with-aneurysmal-subarachnoid-hemorrhage
#16
S A Abudeev, K A Popugaev, N M Kruglyakov, K A Belousova, D A Terekhov, K Yu Leushin, M S Aronov, O V Karpova, A V Zelenkov, K V Kiselev, A B Fedin, M V Zabelin, A S Samoylov
Aneurysmal subarachnoid hemorrhage is a serious medical and social problem. The main physiological mechanisms that determine secondary brain damage in this patients are intracranial hypertension, cerebral vasospasm, dysfunction of autoregulation mechanisms, violation of liquorodynamics and delayed cerebral ischemia. The multimodal neuromonitoring for prevention and timely correction ofsecondary brain injury factors has become routine practice in neuroICU. Measurement of oxygen tension in the brain parenchyma is one of neuromonitoring options...
March 2016: Anesteziologiia i Reanimatologiia
https://www.readbyqxmd.com/read/27444002/central-nervous-system-complications-of-hematopoietic-stem-cell-transplant
#17
REVIEW
Faiz I Syed, Daniel R Couriel, David Frame, Ashok Srinivasan
Hematopoietic stem cell transplantation (SCT) is now commonly used to treat several hematologic and nonhematologic diseases. Central nervous system (CNS) complications post-transplantation occur commonly in the first year and result in increased mortality from infectious, toxic, metabolic, or vascular causes. Infections secondary to aspergillus, toxoplasma and viruses cause many of the complications. Drug-related toxicities arising from conditioning regimens and graft-versus-host disease prophylaxis, as well as intraparenchymal hemorrhage, are not uncommon and can result in increased morbidity...
August 2016: Hematology/oncology Clinics of North America
https://www.readbyqxmd.com/read/27442784/placental-pathologic-associations-with-morbidly-adherent-placenta-potential-insights-into-pathogenesis
#18
Linda M Ernst, Rebecca L Linn, Lucy Minturn, Emily S Miller
BACKGROUND: The pathology that underlies morbidly adherent placenta (MAP) is poorly understood. The objective of this study was to describe the placental pathology, especially implantation site pathology, associated with MAP. METHODS: This was a single institution, retrospective case-control study design examining placentas of patients who delivered between January 2008 and September 2013. MAP cases were defined by the need for clinical intervention at delivery beyond spontaneous placental delivery or simple manual extraction of the placenta...
July 21, 2016: Pediatric and Developmental Pathology
https://www.readbyqxmd.com/read/27439887/mid-term-and-long-term-follow-up-of-intracranial-aneurysms-treated-by-the-p64-flow-modulation-device-a-multicenter-experience
#19
Francesco Briganti, Giuseppe Leone, Lorenzo Ugga, Mariano Marseglia, Antonio Macera, Andrea Manto, Luigi Delehaye, Maurizio Resta, Mariachiara Resta, Nicola Burdi, Nunzio Paolo Nuzzi, Ignazio Divenuto, Ferdinando Caranci, Mario Muto, Domenico Solari, Paolo Cappabianca, Francesco Maiuri
BACKGROUND: Experience with the endovascular treatment of cerebral aneurysms using the p64 Flow Modulation Device is still limited. This study discusses the results and complications of this new flow diverter device. METHODS: 40 patients (30 women, 10 men) with 50 cerebral aneurysms treated in six Italian neurointerventional centers with the p64 Flow Modulation Device between April 2013 and September 2015 were retrospectively reviewed. RESULTS: Complete occlusion was obtained in 44/50 aneurysms (88%) and partial occlusion in 3 (6%)...
July 20, 2016: Journal of Neurointerventional Surgery
https://www.readbyqxmd.com/read/27432674/hemorrhagic-cerebrovascular-disease
#20
Javier M Romero, Jonathan Rosand
Primary or nontraumatic spontaneous intracerebral hemorrhage (ICH) accounts for 10-15% of all strokes, and has a poor prognosis. ICH has a mortality rate of almost 50% when associated with intraventricular hemorrhage within the first month, and 80% rate of dependency at 6 months from onset. Neuroimaging is critical in identifying the underlying etiology and thus assisting in the important therapeutic decisions. There are several imaging modalities available in the workup of patients who present with ICH, including computed tomography (CT), magnetic resonance imaging (MRI), and digital subtraction angiography (DSA)...
2016: Handbook of Clinical Neurology
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