Jie Kang, Lei Cao, Taoyang Yuan, Lu Jin, Yanjiao He, Xing Liu, Cuiping Zhang, Nan Chen, Guofo Ma, Ning Qiao, Bochao Zhang, Wentao Wu, Yuanyu Shi, Hua Gao, Chuzhong Li, Yazhuo Zhang, Zhentao Zuo, Songbai Gui
Adamantinomatous craniopharyngioma (ACPs) are rare embryonic tumors and often involve the hypothalamus. The underlying neural substrate of the hypothalamic involvement (HI)-related cognitive decline in patients with ACP is still unclear. We aimed to combine the multi-modal neuroimaging and histological characteristics of the ACP to explore the potential neural substrate of the HI-related cognitive decline. 45 patients with primary ACPs (invasive, 23; noninvasive, 22) and 52 healthy control subjects (HCs) were admitted to the cross-sectional study...
September 30, 2022: NeuroImage: Clinical