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https://www.readbyqxmd.com/read/29454278/towards-a-better-understanding-on-mercury-adsorption-by-magnetic-bio-adsorbents-with-%C3%AE-fe-2-o-3-from-pinewood-sawdust-derived-hydrochar-influence-of-atmosphere-in-heat-treatment
#1
Huabin Wang, Yong Liu, Jerosha Ifthikar, Lerong Shi, Aimal Khan, Zhulei Chen, Zhuqi Chen
Pyrolysis under protective atmosphere was regarded as an indispensable process for the preparation of biomass-based adsorbents to achieve higher surface areas. In this paper, magnetic carbon composites (MCC) that fabricated under air atmosphere showed an adsorption capacity of 167.22 mg/g in 200 ppm Hg(II), which was significantly higher than magnetic biochar (MBC, 31.80 mg/g) that fabricated under traditional nitrogen protection, and this remarkable performance of MCC was consistent in a wide range of pHs...
February 6, 2018: Bioresource Technology
https://www.readbyqxmd.com/read/29453129/efficient-visible-light-induced-synthesis-of-silver-nanoparticles-by-penicillium-polonicum-ara-10-isolated-from-chetomorpha-antennina-and-its-antibacterial-efficacy-against-salmonella-enterica-serovar-typhimurium
#2
Sahadevan Neethu, Sebastian Jose Midhun, M A Sunil, Soman Soumya, E K Radhakrishnan, Mathew Jyothis
The green synthesis of silver nanoparticles (AgNPs) using biological systems such as fungi has evolved to become an important area of nanobiotechnology. Herein, we report for the first time the light-induced extracellular synthesis of silver nanoparticles using algicolous endophytic fungus Penicillium polonicum ARA 10, isolated from the marine green alga Chetomorpha antennina. Parametric optimization, including the concentration of AgNO 3 , fungal biomass, ratio of cell filtrate and AgNO 3 , pH, reaction time and presence of light, was done for rapid AgNPs production...
February 7, 2018: Journal of Photochemistry and Photobiology. B, Biology
https://www.readbyqxmd.com/read/29452197/essential-oils-from-origanum-vulgare-and-salvia-officinalis-exhibit-antibacterial-and-anti-biofilm-activities-against-streptococcus-pyogenes
#3
Niluni M Wijesundara, H P Vasantha Rupasinghe
In the present study, essential oils (EOs) extracted from oregano, sage, cloves, and ginger were evaluated for the phytochemical profile, antibacterial, and anti-biofilm activities against Streptococcus pyogenes. The broth microdilution method was used to determine the minimal inhibitory concentration (MIC) and minimal bactericidal concentration (MBC) of EOs. The minimum biofilm inhibitory concentrations (MBICs) were determined using MTT assay and fixed biofilms were observed through scan electron microscopy...
February 13, 2018: Microbial Pathogenesis
https://www.readbyqxmd.com/read/29450827/progression-free-survival-results-in-postmenopausal-asian-women-subgroup-analysis-from-a-phase-iii-randomized-trial-of-fulvestrant-500-mg-vs-anastrozole-1-mg-for-hormone-receptor-positive-advanced-breast-cancer-falcon
#4
Shinzaburo Noguchi, Matthew J Ellis, John F R Robertson, Jackie Thirlwell, Mehdi Fazal, Zhimin Shao
BACKGROUND: The international, phase III FALCON study (NCT01602380) in postmenopausal patients with hormone receptor-positive, locally advanced/metastatic breast cancer (LA/MBC) who had not received prior endocrine therapy, demonstrated statistically significant improvement in progression-free survival (PFS) for patients who received fulvestrant 500 mg vs anastrozole 1 mg. This subgroup analysis evaluated PFS in Asian (randomized in China, Japan, or Taiwan) and non-Asian patients from the FALCON study...
February 15, 2018: Breast Cancer: the Journal of the Japanese Breast Cancer Society
https://www.readbyqxmd.com/read/29449315/metaplastic-breast-cancer-in-a-patient-with-neurofibromatosis-type-1-and-somatic-loss-of-heterozygosity
#5
Lorena Suarez-Kelly, Keiko Akagi, Julie W Reeser, Eric Samorodnitsky, Matthew Reeder, Amy Smith, Sameek Roychowdhury, David E Symer, William E Carson
Metaplastic breast carcinoma (MBC) is rare and has a poor prognosis. Here we describe genetic analysis of a 41-year-old female patient with MBC and neurofibromatosis type I (NF1). She initially presented with pT3N1a, grade 3 MBC, but lung metastases were discovered subsequently. To identify the molecular cause of her NF1, we screened for germline mutations disrupting NF1 or SPRED1, revealing a heterozygous germline single nucleotide variant (SNV) in exon 21 of NF1 at c.2709G>A, chr17: 29556342. By report, this variant disrupts pre-mRNA splicing of NF1 transcripts...
February 15, 2018: Cold Spring Harbor Molecular Case Studies
https://www.readbyqxmd.com/read/29447075/propionibacterium-acnes-has-low-susceptibility-to-chlorhexidine-digluconate
#6
Keisuke Nakase, Hanae Fukushima, Tomoko Yukawa, Hidemasa Nakaminami, Takeshi Fujii, Norihisa Noguchi
BACKGROUND: The skin bacterium Propionibacterium acnes has been reported to be responsible for surgical site infections (SSIs). Skin disinfection before surgery therefore is of the utmost importance in the prevention of SSIs caused by skin bacteria. METHODS: We assessed the susceptibility of clinical isolates of two skin bacteria, P. acnes and Staphylococcus epidermidis, to disinfectants. RESULTS: The range of chlorhexidine digluconate (CHG) minimum inhibitory concentrations (MICs) for P...
February 15, 2018: Surgical Infections
https://www.readbyqxmd.com/read/29437779/the-elmo-mbc-complex-and-rhogap19d-couple-rho-family-gtpases-during-mesenchymal-to-epithelial-like-transitions
#7
Christopher P Toret, Pruthvi C Shivakumar, Pierre-François Lenne, Andre Le Bivic
Many metazoan developmental processes require cells to transition between migratory mesenchymal- and adherent epithelial-like states. These transitions require Rho GTPase-mediated actin rearrangements downstream of integrin and cadherin pathways. A regulatory toolbox of GEF and GAP proteins precisely coordinates Rho protein activities, yet defining the involvement of specific regulators within a cellular context remains a challenge due to overlapping and coupled activities. Here we demonstrate that Drosophila dorsal closure is a powerful model for Rho GTPase regulation during transitions from leading edges to cadherin contacts...
February 2, 2018: Development
https://www.readbyqxmd.com/read/29435798/response-of-soil-microbial-communities-to-red-mud-based-stabilizer-remediation-of-cadmium-contaminated-farmland
#8
Hui Li, Lemian Liu, Lin Luo, Yan Liu, Jianhong Wei, Jiachao Zhang, Yuan Yang, Anwei Chen, Qiming Mao, Yaoyu Zhou
In this work, a field test was conducted to investigate the effects of heavy metal stabilizer addition on brown rice and microbial variables in a cadmium (Cd)-contaminated farmland from April to October in 2016. Compared with the control, red mud-based stabilizer (RMDL) effectively reduced the concentration of Cd in brown rice (with the removal rate of 48.14% in early rice, 20.24 and 47.62% in late rice). The results showed that adding 0.3 kg m-2 RDML in early rice soil or soil for both early and late rice increased the microbial biomass carbon (MBC), the number of culturable heterotrophic bacteria and fungi, and the catalase activity in soil at different stages of paddy rice growth...
February 12, 2018: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/29435730/bi-weekly-eribulin-therapy-for-metastatic-breast-cancer-a-multicenter-phase-ii-prospective-study-just-study
#9
Shoichiro Ohtani, Takahiro Nakayama, Tetsuhiro Yoshinami, Ken-Ichi Watanabe, Fumikata Hara, Yasuaki Sagara, Hidetoshi Kawaguchi, Kenji Higaki, Nobuki Matsunami, Yoshie Hasegawa, Masato Takahashi, Makiko Mizutani, Takashi Morimoto, Masako Sato, Mitsuya Itoh, Satoshi Morita, Norikazu Masuda
BACKGROUND: This study aimed to investigate whether schedule modification is safe and effective in patients intolerant to the standard eribulin dose and schedule. METHODS: Patients with metastatic breast cancer (MBC) treated with both anthracycline and taxane and ≤ 3 prior regimens of chemotherapy for MBC received eribulin at the standard dose and schedule (1.4 mg/m2 on days 1 and 8 of a 21-day cycle) in the first cycle; change of dosing schedule (1.4 mg/m2 on days 1 and 15 of a 28-day cycle) was determined by change in neutrophil count, platelet count, aspartate aminotransferase, alanine aminotransferase, total bilirubin, serum creatinine, and non-hematological toxicity on day 8 of the first cycle or day 1 of the second cycle...
February 12, 2018: Breast Cancer: the Journal of the Japanese Breast Cancer Society
https://www.readbyqxmd.com/read/29432643/growth-media-and-assay-plate-material-can-impact-on-the-effectiveness-of-cationic-biocides-and-antibiotics-against-different-bacterial-species
#10
Lucy J Bock, Charlotte K Hind, J Mark Sutton, Matthew E Wand
The effectiveness of several cationic disinfectants as well as colistin and polymyxin B were assessed under different growth conditions against Staphylococcus aureus, Escherichia coli and Pseudomonas aeruginosa strains. These conditions included different media (MH1, MH2, TSB and LB) and plate material (polypropylene and polystyrene). Results showed that MIC/MBC values of colistin and polymyxin B were significantly lower on polypropylene plates when compared to polystyrene plates regardless of media used. There were also differences for MIC/MBC values to certain biocides e...
February 12, 2018: Letters in Applied Microbiology
https://www.readbyqxmd.com/read/29429665/sonochemical-solvothermal-synthesis-of-guanine-embedded-copper-based-metal-organic-framework-mof-and-its-effect-on-oprd-gene-expression-in-clinical-and-standard-strains-of-pseudomonas-aeruginosa
#11
Farideh Abbasloo, Seyed Abdolmajid Khosravani, Mehrorang Ghaedi, Kheibar Dashtian, Ebrahim Hosseini, Leila Manzouri, Seyed Sajjad Khorramrooz, Asghar Sharifi, Ramin Jannesar, Farzad Sadri
The guanine incropped Cu based metal-organic framework (Guanine-Cu-MOF) was synthesized by facile one-step sonochemical method by simply mixing of 4-4, biphenyldicarboxylic, guanine and copper nitrate (Bio-Cu-H2bpdc-Gu). The prepared guanine-MOF was characterized by using X-Ray diffraction (XRD), Fourier-transform infrared spectroscopy (FTIR), and Field emission scanning electron microscopy (FE-SEM) techniques. The morphology of prepared material was sponge-shaped which it was well documented, together with the presence of existing functional groups...
April 2018: Ultrasonics Sonochemistry
https://www.readbyqxmd.com/read/29428373/first-line-paclitaxel-and-cisplatin-used-sequentially-or-in-combination-in-metastatic-breast-cancer-a-phase-ii-randomized-study
#12
Mostafa M Elserafi, Ahmed A Zeeneldin, Ibrahim M Abdelsalam, Hanan R Nassar, Manar M Moneer, Wafa H Buhoush
INTRODUCTION: Breast cancer (BC) is the commonest cancer among females worldwide. Some patients present initially at advanced stages and more than 50% of them will develop metastasis (MBC) at some point. Compared to single agents, combination chemotherapy produces higher response rates (RR), longer progression-free survival (PFS) than single agents. This is associated with remarkably higher toxicities. At the same time, overall survival (OS) is comparable. This study aimed to compare safety and efficacy of combination and sequential chemotherapy...
February 7, 2018: Journal of the Egyptian National Cancer Institute
https://www.readbyqxmd.com/read/29427473/antimicrobial-and-cytotoxic-activity-of-silver-nanoparticles-synthesized-from-two-haloalkaliphilic-actinobacterial-strains-alone-and-in-combination-with-antibiotics
#13
Magdalena Wypij, Magdalena Świecimska, Joanna Czarnecka, Hanna Dahm, Mahendra Rai, Patrycja Golinska
AIMS: Presently, the effective antimicrobial agents have been limited by emergence of microbial strains with multi-drug resistance and biofilm formation potential. In the present study, we report remarkable antimicrobial activity of silver nanoparticles (AgNPs) synthesized from Streptomyces calidiresistens IF11 and IF17 strains, including inhibition of biofilm formation and synergistic effect of AgNPs and antibiotics against selected bacteria and yeasts. Cytotoxic effect of AgNPs on mammalian cell lines was also evaluated...
February 10, 2018: Journal of Applied Microbiology
https://www.readbyqxmd.com/read/29424755/the-accuracy-of-portable-ultrasound-bladder-scanner-measurements-of-postvoid-residual-volume-in-women-with-pelvic-organ-prolapse
#14
John Graham Theisen, Nicolette E Deveneau, Anu Agrawal, Casey Kinman, Jeremy Gaskins, Kate Meriwether, Sean L Francis
OBJECTIVES: The purpose of this study was to evaluate the accuracy of portable bladder scanner postvoid residual (PVR) volume measurements in patients with pelvic organ prolapse. A secondary goal was to determine whether covariates such as bladder volume and stage of prolapse affect bladder scanner accuracy. STUDY DESIGN: Complex urodynamic studies were performed on 70 patients with stage II or greater prolapse. Complex urodynamic studies included measurement of maximum bladder capacity (MBC) as well as measurement of PVR by urethral catheterization before, and following, complex filling cystometry...
February 8, 2018: Female Pelvic Medicine & Reconstructive Surgery
https://www.readbyqxmd.com/read/29423561/colistin-causes-profound-morphological-alteration-but-minimal-cytoplasmic-membrane-perforation-in-populations-of-escherichia-coli-and-pseudomonas-aeruginosa
#15
Noëlle H O'Driscoll, T P Tim Cushnie, Kerr H Matthews, Andrew J Lamb
Whilst colistin (polymyxin E) represents the last mainstream treatment option for multidrug-resistant Gram-negative pathogens, details of its mechanism of action remain to be fully resolved. In this study, the effects of sub-inhibitory, inhibitory-bactericidal, and supra-bactericidal levels of colistin on the membrane integrity and morphology of Escherichia coli and Pseudomonas aeruginosa were investigated using potassium loss, flow cytometry, and scanning electron microscopy (SEM). Supra-bactericidal colistin concentrations induced just 4-12% intracellular potassium loss from bacteria after 24 h...
February 8, 2018: Archives of Microbiology
https://www.readbyqxmd.com/read/29415973/antibacterial-activity-and-dentin-bonding-ability-of-combined-use-of-clearfil-se-protect-and-sodium-hypochlorite
#16
Ilijana Muratovska, Haruaki Kitagawa, Nanako Hirose, Ranna Kitagawa, Satoshi Imazato
The aim of this study was to evaluate the antibacterial activity and dentin bonding ability of a commercial self-etch adhesive Clearfil SE Protect (Kuraray Noritake Dental, Tokyo, Japan) in combination with sodium hypochlorite (NaOCl). Agar disc diffusion tests and measurement of minimum inhibitory/bactericidal concentrations (MIC/MBC) against Streptococcus mutans were performed to evaluate antibacterial effects. The mixture solution of 5.25% NaOCl and the primer of Clearfil SE Protect demonstrated less antibacterial activity than primer only...
February 8, 2018: Dental Materials Journal
https://www.readbyqxmd.com/read/29413403/oral-etoposide-in-heavily-pre-treated-metastatic-breast-cancer-a-retrospective-series
#17
G Giannone, A Milani, E Ghisoni, S Genta, G Mittica, F Montemurro, G Valabrega
BACKGROUND: Patients with metastatic breast cancer (MBC) can derive clinical benefit from several subsequent lines of chemotherapy. However, in heavily pre-treated patients, agents with clinical activity, a favourable side effects profile and a convenient administration modality are preferred. PATIENTS AND METHODS: We retrospectively analyzed 110 patients with previously treated MBC, who received oral etoposide at the dose of 50 mg/day for 20 days in 28 days cycles, between 2003 and 2017...
January 29, 2018: Breast: Official Journal of the European Society of Mastology
https://www.readbyqxmd.com/read/29413402/omission-of-radiotherapy-in-elderly-women-with-early-stage-metaplastic-breast-cancer
#18
Waqar Haque, Vivek Verma, E Brian Butler, Bin S Teh
PURPOSE: Multiple studies have evaluated the omission of radiation therapy (RT) in elderly women with invasive carcinoma; no studies to date have assessed this question for metaplastic breast cancer (MBC). This study is the only known study describing national practice patterns and addressing the impact of RT versus observation on survival in elderly women with T1-2N0 MBC. METHODS: The National Cancer Data Base was queried (2004-2013) for women aged ≥70 years with T1-T2N0 MBC that underwent lumpectomy...
January 29, 2018: Breast: Official Journal of the European Society of Mastology
https://www.readbyqxmd.com/read/29412250/susceptibility-of-cariogenic-microorganisms-to-phytoconstituents
#19
G L S Ferreira, L M D Bezerra, I L A Ribeiro, R C D Morais Júnior, R D Castro
This study aimed to evaluate the in vitro antibacterial activity of the phytochemicals thymol, linalool, and citronellol against Streptococcus mutans, Streptococcus salivarius and Streptococcus oralis. Disk diffusion screening on solid medium and measurement of the diameter of the bacterial growth inhibition halos was the technique utilized. The Minimum Inhibitory Concentration (MIC) of the substances was determined using serial substance dilutions and microdilution technique in Brain Heart Infusion culture medium...
February 1, 2018: Brazilian Journal of Biology, Revista Brasleira de Biologia
https://www.readbyqxmd.com/read/29407907/silver-complex-of-salicylic-acid-and-its-hydrogel-cream-in-wound-healing-chemotherapy
#20
Maria-Eleni K Stathopoulou, Christina N Banti, Nikolaos Kourkoumelis, Antonios G Hatzidimitriou, Angelos G Kalampounias, Sotiris K Hadjikakou
The known metallotherapeutic [Ag(salH)]2 (AGSAL-1) of salicylic acid (salH2), was used for the development of new efficient silver based material for wounds healing. AGSAL-1 was characterized by spectroscopic techniques and X-ray crystallography. The wound healing epithelialization of AGSAL-1 was investigated by the means of scratch assay against immortalized human keratinocytes (HaCaT) cells. The anti-inflammatory activity of AGSAL-1 was evaluated by monitoring the catalytic peroxidation of linoleic acid to hydroperoxylinoleic acid by the enzyme lipoxygenase (LOX)...
February 1, 2018: Journal of Inorganic Biochemistry
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