keyword
MENU ▼
Read by QxMD icon Read
search

Cytochrome c oxidase

keyword
https://www.readbyqxmd.com/read/28816609/evidence-of-diversity-site-and-host-specificity-of-sea-turtle-blood-flukes-digenea-schistosomatoidea-spirorchiidae-a-molecular-prospecting-study
#1
Brian A Stacy, Phoebe A Chapman, Allen M Foley, Ellis C Greiner, Lawrence H Herbst, Alan B Bolten, Paul A Klein, Charles A Manire, Elliott R Jacobson
Neospirorchis (Digenea: "Spirorchiidae") are blood flukes of sea turtles. Trematodes tentatively identified as Neospirorchis sp. infect various sites within sea turtles inhabiting waters of the southeastern United States, but efforts to obtain specimens adequate for morphologic study has proven difficult. Two genetic targets, the internal transcribed spacer region of the ribosomal RNA gene and the partial mitochrondrial cytochrome c oxidase subunit I gene, were used to investigate potential diversity among parasite specimens collected from stranded sea turtles...
August 17, 2017: Journal of Parasitology
https://www.readbyqxmd.com/read/28814504/osm1-facilitates-the-transfer-of-electrons-from-erv1-to-fumarate-in-the-redox-regulated-import-pathway-in-the-mitochondrial-intermembrane-space
#2
Sonya E Neal, Deepa V Dabir, Juwina Wijaya, Cennyana Boon, Carla M Koehler
Prokaryotes have aerobic and anaerobic electron acceptors for oxidative folding of periplasmic proteins. The mitochondrial intermembrane space has an analogous pathway with the oxidoreductase Mia40 and sulfhydryl oxidase Erv1, termed the MIA pathway. The aerobic electron acceptors include oxygen and cytochrome c, but an acceptor that can function under anaerobic conditions has not been identified. Here we show that the fumarate reductase Osm1, which facilitates electron transfer from fumarate to succinate, fills this gap as a new electron acceptor...
August 16, 2017: Molecular Biology of the Cell
https://www.readbyqxmd.com/read/28813463/genetic-diversity-of-bemisia-tabaci-species-colonizing-cassava-in-central-african-republic-characterized-by-analysis-of-cytochrome-c-oxidase-subunit-i
#3
Brice Kette Tocko-Marabena, Semballa Silla, Christophe Simiand, Innocent Zinga, James Legg, Bernard Reynaud, Helene Delatte
After 2007, upsurges of whiteflies on cassava plants and high incidences of cassava diseases were observed in Central African Republic. This recent upsurge in the abundance of Bemisia tabaci (Gennadius) (Hemiptera: Aleyrodidae) was directly linked to serious damage to cassava crops resulting from spread of whitefly-borne cassava mosaic geminiviruses (CMGs). There is currently very little information describing whitefly populations on cassava and associated crops in Central African Republic. The current study aimed to address this gap, and to determine whether the increasing damage associated with B...
2017: PloS One
https://www.readbyqxmd.com/read/28813209/galangin-a-natural-flavonoid-reduces-mitochondrial-oxidative-damage-in-streptozotocin-induced-diabetic-rats
#4
Amal A Aloud, Chinnadurai Veeramani, Chandramohan Govindasamy, Mohammed A Alsaif, Khalid S Al-Numair
OBJECTIVE: We designed this study to observe the effect of galangin on damaged mitochondria in the liver of diabetic rats. METHODS: Male albino Wistar rats were made diabetic by injecting streptozotocin (STZ) intraperitoneally (40 mg kg(-1) body weight (BW)). Galangin (8 mg kg(-1) BW) or glibenclamide (600 µg kg(-1) BW) was given orally daily once for 45 days to both healthy and diabetic rats. RESULTS: Diabetic rats showed significant (P < 0...
August 16, 2017: Redox Report: Communications in Free Radical Research
https://www.readbyqxmd.com/read/28808085/sub-mitochondrial-localization-of-genetic-tagged-mib-interacting-partners-mic19-mic60-and-sam50
#5
Mira Sastri, Manjula Darshi, Mason Mackey, Ranjan Ramachandra, Saeyeon Ju, Sebastien Phan, Stephen Adams, Kathryn Stein, Christopher R Douglas, Jiwan John Kim, Mark H Ellisman, Susan S Taylor, Guy A Perkins
Each mitochondrial compartment contains varying protein compositions that underlie a diversity of localized functions. Insights into the localization of mitochondrial intermembrane space bridging (MIB) components will have an impact on our understanding of mitochondrial architecture, dynamics and function. Using the novel visualizable genetic tags miniSOG and APEX2 in cultured mouse cardiac and human astrocyte cell lines and electron tomography, we have mapped at nanoscale resolution three key MIB components: Mic19, Mic60 and Sam50, in the environment of structural landmarks such as cristae and crista junctions (CJs)...
August 14, 2017: Journal of Cell Science
https://www.readbyqxmd.com/read/28807731/time-resolved-generation-of-membrane-potential-by-ba3-cytochrome-c-oxidase-from-thermus-thermophilus-coupled-to-single-electron-injection-into-the-o-and-oh-states
#6
Sergey A Siletsky, Ilya Belevich, Nikolay P Belevich, Tewfik Soulimane, Mårten Wikström
Two electrogenic phases with characteristic times of ~14μs and ~290μs are resolved in the kinetics of membrane potential generation coupled to single-electron reduction of the oxidized "relaxed" O state of ba3 oxidase from T. thermophilus (O→E transition). The rapid phase reflects electron redistribution between CuA and heme b. The slow phase includes electron redistribution from both CuA and heme b to heme a3, and electrogenic proton transfer coupled to reduction of heme a3. The distance of proton translocation corresponds to uptake of a proton from the inner water phase into the binuclear center where heme a3 is reduced, but there is no proton pumping and no reduction of CuB...
August 11, 2017: Biochimica et Biophysica Acta
https://www.readbyqxmd.com/read/28803790/utility-of-the-cytochrome-c-oxidase-subunit-i-gene-for-the-diagnosis-of-toxoplasmosis-using-pcr
#7
Xue Feng, Kazumi Norose, Kexin Li, Kenji Hikosaka
Toxoplasmosis is caused by the protozoan parasite Toxoplasma gondii, which belongs to the phylum Apicomplexa. Since this parasite causes severe clinical symptoms in immunocompromised patients, early diagnosis of toxoplasmosis is essential. PCR is currently used for early diagnosis, but there is no consensus regarding the most effective method for amplifying Toxoplasma DNA. In this study, we considered the utility of the cytochrome c subunit I (cox1) gene, which is encoded in the mitochondrial DNA of this parasite, as a novel target of PCR for the diagnosis of toxoplasmosis...
August 10, 2017: Journal of Microbiological Methods
https://www.readbyqxmd.com/read/28803751/insulin-prevents-aberrant-mitochondrial-phenotype-in-sensory-neurons-of-type-1-diabetic-rats
#8
Mohamad-Reza Aghanoori, Darrell R Smith, Subir Roy Chowdhury, Mohammad Golam Sabbir, Nigel A Calcutt, Paul Fernyhough
Diabetic neuropathy affects approximately 50% of diabetic patients. Down-regulation of mitochondrial gene expression and function has been reported in both human tissues and in dorsal root ganglia (DRG) from animal models of type 1 and type 2 diabetes. We hypothesized that loss of direct insulin signaling in diabetes contributes to loss of mitochondrial function in DRG neurons and to development of neuropathy. Sensory neurons obtained from age-matched adult control or streptozotocin (STZ)-induced type 1 diabetic rats were cultured with or without insulin before determining mitochondrial respiration and expression of mitochondrial respiratory chain and insulin signaling-linked proteins...
August 10, 2017: Experimental Neurology
https://www.readbyqxmd.com/read/28801051/the-mechanism-for-oxygen-reduction-in-cytochrome-c-dependent-nitric-oxide-reductase-cnor-as-obtained-from-a-combination-of-theoretical-and-experimental-results
#9
Margareta R A Blomberg, Pia Ädelroth
Bacterial NO-reductases (NOR) belong to the heme-copper oxidase (HCuO) superfamily, in which most members are O2-reducing, proton-pumping enzymes. This study is one in a series aiming to elucidate the reaction mechanisms of the HCuOs, including the mechanisms for cellular energy conservation. One approach towards this goal is to compare the mechanisms for the different types of HCuOs, cytochrome c oxidase (CcO) and NOR, reducing the two substrates O2 and NO. Specifically in this study, we describe the mechanism for oxygen reduction in cytochrome c dependent NOR (cNOR)...
August 8, 2017: Biochimica et Biophysica Acta
https://www.readbyqxmd.com/read/28801050/electron-transfer-through-arsenite-oxidase-insights-into-rieske-interaction-with-cytochrome-c
#10
Cameron Watson, Dimitri Niks, Russ Hille, Marta Vieira, Barbara Schoepp-Cothenet, Alexandra T Marques, Maria João Romão, Teresa Santos-Silva, Joanne M Santini
Arsenic is a widely distributed environmental toxin whose presence in drinking water poses a threat to >140 million people worldwide. The respiratory enzyme arsenite oxidase from various bacteria catalyses the oxidation of arsenite to arsenate and is being developed as a biosensor for arsenite. The arsenite oxidase from Rhizobium sp. str. NT-26 (a member of the Alphaproteobacteria) is a heterotetramer consisting of a large catalytic subunit (AioA), which contains a molybdenum centre and a 3Fe-4S cluster, and a small subunit (AioB) containing a Rieske 2Fe-2S cluster...
August 8, 2017: Biochimica et Biophysica Acta
https://www.readbyqxmd.com/read/28800112/low-concentration-tributyltin-decreases-glur2-expression-via-nuclear-respiratory-factor-1-inhibition
#11
Keishi Ishida, Kaori Aoki, Tomoko Takishita, Masatsugu Miyara, Shuichiro Sakamoto, Seigo Sanoh, Tomoki Kimura, Yasunari Kanda, Shigeru Ohta, Yaichiro Kotake
Tributyltin (TBT), which has been widely used as an antifouling agent in paints, is a common environmental pollutant. Although the toxicity of high-dose TBT has been extensively reported, the effects of low concentrations of TBT are relatively less well studied. We have previously reported that low-concentration TBT decreases α-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (AMPA)-type glutamate receptor subunit 2 (GluR2) expression in cortical neurons and enhances neuronal vulnerability to glutamate. However, the mechanism of this TBT-induced GluR2 decrease remains unknown...
August 11, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28797792/specific-status-of-echinococcus-canadensis-cestoda-taeniidae-inferred-from-nuclear-and-mitochondrial-gene-sequences
#12
Tetsuya Yanagida, Antti Lavikainen, Eric P Hoberg, Sergey Konyaev, Akira Ito, Marcello Otake Sato, Vladimir A Zaikov, Kimberlee Beckmen, Minoru Nakao
The specific status of Echinococcus canadensis has long been controversial, mainly because it consists of the mitochondrial lineages G6, G7, G8 and G10 with different host affinity: G6 (camel strain) and G7 (pig strain) with domestic cycles and G8 (cervid strain) and G10 (Fennoscandian cervid strain) with sylvatic or semi-domestic cycles. There is an argument whether the mitochondrial lineages should be recognised as separate species which correspond to the biological or epidemiological aggregation. In the present study, the specific status of E...
August 7, 2017: International Journal for Parasitology
https://www.readbyqxmd.com/read/28797253/first-record-of-anopheles-stephensi-in-sri-lanka-a-potential-challenge-for-prevention-of-malaria-reintroduction
#13
A G Gayan Dharmasiri, A Yashan Perera, Jeevanie Harishchandra, Hemantha Herath, Kandasamy Aravindan, H T R Jayasooriya, Gaya R Ranawaka, Mihirini Hewavitharane
BACKGROUND: The major malaria vector in Sri Lanka is reported to be Anopheles culicifacies with Anopheles subpictus, Anopheles annularis, and Anopheles varuna considered as potential vectors. The occurrence of Anopheles stephensi, which is the key vector of urban malaria in India and the Middle East, had never been reported from Sri Lanka. METHODS: A series of entomological investigations were carried out by the Anti Malaria Campaign, Ministry of Health, Sri Lanka during December 2016 to April 2017 in two localities of the Mannar District in the Northern Province of the country...
August 10, 2017: Malaria Journal
https://www.readbyqxmd.com/read/28793013/in-vitro-effects-of-blepharocalyx-salicifolius-h-b-k-o-berg-on-the-viability-of-echinococcus-ortleppi-protoscoleces
#14
Charlise Bolson Noal, Danieli Urach Monteiro, Thiele Faccim de Brum, Jessica Emmanouilidis, Regis Adriel Zanette, Ademir Farias Morel, Eliza Beti de Cassia Stefanon, Marina Frosi, Mario Luiz de la Rue
Scolicidal agents are important in the treatment of cystic echinococcosis. This study evaluated the scolicidal activity of the plant Blepharocalyx salicifolius (H.B.K.) Berg against Echinococcus ortleppi protoscoleces. The parasite species was identified by amplifying a fragment of the gene cytochrome c oxidase subunit 1 (COX 1). B. salicifolius crude extract at concentrations of 100, 200, 300 and 400 mg/mL was analyzed at different times (5, 10, 15, 30, 45 and 60 min). N-butanol and ethyl acetate fractions (100 and 200 mg/ mL) were also analyzed at 5, 10, 15 and 30 min...
2017: Revista do Instituto de Medicina Tropical de São Paulo
https://www.readbyqxmd.com/read/28791381/protective-effect-of-diminazene-attenuates-myocardial-infarction-in-rats-via-increased-inflammation-and-ace2-activity
#15
Junjiang Chen, Lianqun Cui, Jingliang Yuan, Songcun Zhang, Rongmei Ma, Hongjun Sang, Qingjiang Liu, Lianfeng Shan
The present study aimed to investigate whether diminazene attenuates myocardial infarction (MI) in rats. In addition, the present study investigated whether ACE2 signaling was involved in the effects of diminazene on protein function. A rat model of acute myocardial infarction (AMI) was established by occlusion of the left anterior descending coronary artery. The AMI model rats received intraperitoneal injections of diminazene (5 mg/kg/day) for 3 days. Treatment with diminazene significantly inhibited the expression of casein kinase and lactate dehydrogenase, and reduced infarct size in AMI rats...
August 3, 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/28790886/molecular-bases-of-brain-preconditioning
#16
Oleg G Deryagin, Svetlana A Gavrilova, Khalil L Gainutdinov, Anna V Golubeva, Vyatcheslav V Andrianov, Guzel G Yafarova, Sergey V Buravkov, Vladimir B Koshelev
Preconditioning of the brain induces tolerance to the damaging effects of ischemia and prevents cell death in ischemic penumbra. The development of this phenomenon is mediated by mitochondrial adenosine triphosphate-sensitive potassium ([Formula: see text]) channels and nitric oxide signaling (NO). The aim of this study was to investigate the dynamics of molecular changes in mitochondria after ischemic preconditioning (IP) and the effect of pharmacological preconditioning (PhP) with the [Formula: see text]-channels opener diazoxide on NO levels after ischemic stroke in rats...
2017: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/28780153/the-catholic-taste-of-broad-tapeworms-multiple-routes-to-human-infection
#17
Andrea Waeschenbach, Jan Brabec, Tomáš Scholz, D Timothy J Littlewood, Roman Kuchta
Broad tapeworms (Cestoda: Diphyllobothriidea) are the principal agents of widespread food-borne cestodosis. Diphyllobothriosis and diplogonoporosis, caused by members of the genera Diphyllobothrium, Diplogonoporus and Adenocephalus, are the most common fish cestodoses with an estimated 20million people infected worldwide, and has seen recent (re)emergences in Europe due to the increasing popularity of eating raw or undercooked fish. Sparganosis is a debilitating and potentially lethal disease caused by the larvae of the genus Spirometra, which occurs throughout much of the (sub)tropics and is caused by the consumption of raw snakes and frogs, and drinking water contaminated by infected copepods...
August 3, 2017: International Journal for Parasitology
https://www.readbyqxmd.com/read/28780151/genetic-differentiation-of-the-g6-7-cluster-of-echinococcus-canadensis-based-on-mitochondrial-marker-genes
#18
Francis Addy, Marion Wassermann, Dorothy Kagendo, Dennis Ebi, Eberhard Zeyhle, Ibrahim E Elmahdi, Gerald Umhang, Adriano Casulli, Majid F Harandi, Ortwin Aschenborn, Peter Kern, Ute Mackenstedt, Thomas Romig
Among the genotype/species causing cystic echinococcosis, the taxonomic status of Echinococcus canadensis is only partially resolved. Within E. canadensis, four genotypes (G6, G7, G8 and G10) have been described based on short mitochondrial sequences, of which G6 and G7 (the 'camel' and the 'pig' strain, respectively) are closely related and variously regarded as microvariants of a single strain G6/7. Globally, this G6/7 cluster is the second most important agent of human cystic echinococcosis and is the predominant Echinococcus taxon in large parts of sub-Saharan Africa...
August 3, 2017: International Journal for Parasitology
https://www.readbyqxmd.com/read/28777108/genetics-in-inclusion-body-myositis
#19
Simon Rothwell, James B Lilleker, Janine A Lamb
PURPOSE OF REVIEW: To review the advances in our understanding of the genetics of inclusion body myositis (IBM) in the past year. RECENT FINDINGS: One large genetic association study focusing on immune-related genes in IBM has refined the association within the human leukocyte antigen (HLA) region to HLA-DRB1 alleles, and identified certain amino acid positions in HLA-DRB1 that may explain this risk. A suggestive association with CCR5 may indicate genetic overlap with other autoimmune diseases...
August 1, 2017: Current Opinion in Rheumatology
https://www.readbyqxmd.com/read/28770680/evaluation-of-the-systematic-status-of-geographical-variations-in-arcuphantes-hibanus-arachnida-araneae-linyphiidae-with-descriptions-of-two-new-species
#20
Takafumi Nakano, Yoh Ihara, Yusuke Kumasaki, Yuki G Baba, Ko Tomikawa
The systematic status of geographical variants of Arcuphantes hibanus Saito, 1992 belonging to the A. longiscapus species group, indigenous to western Honshu and Shikoku, Japan, was evaluated using morphological and molecular data. Two species, A. enmusubi Ihara, Nakano and Tomikawa, sp. nov. and A. occidentalis Ihara, Nakano and Tomikawa, sp. nov., are described, and A. hibanus is redescribed with redefinition of its taxonomic status. These three species are diagnosed by the characteristics of paracymbium, pseudolamella, and epigynal basal part...
August 2017: Zoological Science
keyword
keyword
9397
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"