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Review article in neurology

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https://www.readbyqxmd.com/read/29912447/body-structure-function-activity-and-participation-in-3-to-6-year-old-children-born-very-preterm-an-icf-based-systematic-review-and-meta-analysis
#1
Tara L FitzGerald, Amanda K L Kwong, Jeanie L Y Cheong, Jennifer L McGinley, Lex W Doyle, Alicia J Spittle
Background: The World Health Organization's International Classification of Functioning, Disability and Health framework, Children and Youth Version (ICF-CY), provides a valuable method of conceptualizing the multidomain difficulties experienced by children born very preterm (VP). Reviews investigating motor outcomes at preschool age across ICF-CY domains are lacking. Purpose: The purpose of this review is to identify and compare motor outcomes of 3- to 6-year-old children born VP and children born full term (FT) within the ICF-CY framework...
April 18, 2018: Physical Therapy
https://www.readbyqxmd.com/read/29906432/cuban-epidemic-optic-neuropathy-1991-1993-and-jos%C3%A3-saramago-s-novel-blindness-1995
#2
Robert M Feibel, Jennifer Arch
PURPOSE: This article reviews the history of Cuban Epidemic Optic Neuropathy (1991-1993), which caused visual loss, peripheral neuralgias, and other neurological symptoms in over 50,000 persons, an incidence of almost 0.5% of the entire population. The clinical findings, etiology, and treatment are described. We then relate the Cuban epidemic to the fictional epidemic of contagious blindness depicted by Nobel Laureate José Saramago in his 1995 novel Blindness. This novel describes an unnamed modern city in which all inhabitants, except the ophthalmologist's wife, are affected with a white, not black, blindness...
June 12, 2018: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/29904974/anti-glycine-receptor-antibody-related-disease-a-case-series-and-literature-review
#3
Andrew Swayne, Linda Tjoa, Simon Broadley, Sasha Dionisio, David Gillis, Leslie Jacobson, Mark R Woodhall, Andrew McNabb, Daniel Schweitzer, Ben Tsang, Angela Vincent, Sarosh R Irani, Richard Wong, Patrick Waters, Stefan Blum
INTRODUCTION: Antibodies to glycine receptors (GlyR-Abs) were first defined in progressive encephalopathy with rigidity and myoclonus (PERM), but subsequently identified in other clinical presentations. We aimed to assess the clinical associations of all patients identified with GlyR-Abs in Queensland, Australia between April 2014 to May 2017, and compared these to cases reported in the literature. METHODS: A literature review identified the clinical features of all published GlyR-Ab positive cases through online databases...
June 15, 2018: European Journal of Neurology: the Official Journal of the European Federation of Neurological Societies
https://www.readbyqxmd.com/read/29901487/a-core-set-of-outcome-measures-for-adults-with-neurologic-conditions-undergoing-rehabilitation-a-clinical-practice-guideline
#4
Jennifer L Moore, Kirsten Potter, Kathleen Blankshain, Sandra L Kaplan, Linda C OʼDwyer, Jane E Sullivan
BACKGROUND: Use of outcome measures (OMs) in adult neurologic physical therapy is essential for monitoring changes in a patient's status over time, quantifying observations and patient-reported function, enhancing communication, and increasing the efficiency of patient care. OMs also provide a mechanism to compare patient and organizational outcomes, examine intervention effectiveness, and generate new knowledge. This clinical practice guideline (CPG) examined the literature related to OMs of balance, gait, transfers, and patient-stated goals to identify a core set of OMs for use across adults with neurologic conditions and practice settings...
June 12, 2018: Journal of Neurologic Physical Therapy: JNPT
https://www.readbyqxmd.com/read/29901413/melatonin-as-a-treatment-after-traumatic-brain-injury-a-systematic-review-and-meta-analysis-of-the-pre-clinical-and-clinical-literature
#5
Karen Barlow, Michael M J Esser, Myra Veidt, Roslyn Boyd
Traumatic brain injury is common and yet effective treatments of the secondary brain injury are scarce. Melatonin is a potent, non-selective neuroprotective and anti-inflammatory agent that is showing promising results in neonatal brain injury. The aim of this study was to systematically evaluate the pre-clinical and clinical literature for the effectiveness of Melatonin to improve outcome after TBI. Using the systematic review protocol for animal intervention studies (SYRCLE) and Cochrane methodology for clinical studies, a search of English articles was performed...
June 14, 2018: Journal of Neurotrauma
https://www.readbyqxmd.com/read/29900681/envisioning-the-future-of-polymer-therapeutics-for-brain-disorders
#6
REVIEW
Fernanda Rodriguez-Otormin, Aroa Duro-Castano, Inmaculada Conejos-Sánchez, María J Vicent
The growing incidence of brain-related pathologies and the problems that undermine the development of efficient and effective treatments have prompted both researchers and the pharmaceutical industry to search for novel therapeutic alternatives. Polymer therapeutics (PT) display properties well suited to the treatment of neuro-related disorders, which help to overcome the many hidden obstacles on the journey to the central nervous system (CNS). The inherent features of PT, derived from drug(s) conjugation, in parallel with the progress in synthesis and analytical methods, the increasing knowledge in molecular basis of diseases, and collected clinical data through the last four decades, have driven the translation from "bench to bedside" for various biomedical applications...
June 14, 2018: Wiley Interdisciplinary Reviews. Nanomedicine and Nanobiotechnology
https://www.readbyqxmd.com/read/29900089/staphylococcus-lugdunensis-endocarditis-and-cerebrovascular-accident-a-systemic-review-of-risk-factors-and-clinical-outcome
#7
REVIEW
Htoo Kyaw, Felix Raju, Atif Z Shaikh, Aung Naing Lin, Aye T Lin, Joseph Abboud, Sarath Reddy
Infective endocarditis (IE) secondary to Staphylococcus lugdunensis has been increasingly recognized since 1988. IE-related thromboembolism represents an associated complication of the disease and carries a dismal prognosis. However, the incidence of cerebrovascular accident secondary to S. lugdunensis IE is relatively uncommon and its treatment has not been clearly elucidated yet. We performed an extensive literature search using Pubmed, Medline, Scopus, and Google Scholar to identify the articles using the following keywords: 'Staphylococcus lugdunensis', 'infective endocarditis', 'stroke', and 'cerebrovascular accident...
April 12, 2018: Curēus
https://www.readbyqxmd.com/read/29898974/practice-guideline-update-summary-efficacy-and-tolerability-of-the-new-antiepileptic-drugs-ii-treatment-resistant-epilepsy-report-of-the-guideline-development-dissemination-and-implementation-subcommittee-of-the-american-academy-of-neurology-and-the-american
#8
Andres M Kanner, Eric Ashman, David Gloss, Cynthia Harden, Blaise Bourgeois, Jocelyn F Bautista, Bassel Abou-Khalil, Evren Burakgazi-Dalkilic, Esmeralda Llanas Park, John Stern, Deborah Hirtz, Mark Nespeca, Barry Gidal, Edward Faught, Jacqueline French
OBJECTIVE: To update the 2004 American Academy of Neurology guideline for managing treatment-resistant (TR) epilepsy with second- and third-generation antiepileptic drugs (AEDs). METHODS: 2004 criteria were used to systemically review literature (January 2003 to November 2015), classify pertinent studies according to the therapeutic rating scheme, and link recommendations to evidence strength. RESULTS: Forty-two articles were included. RECOMMENDATIONS: The following are established as effective to reduce seizure frequency (Level A): immediate-release pregabalin and perampanel for TR adult focal epilepsy (TRAFE); vigabatrin for TRAFE (not first-line treatment); rufinamide for Lennox-Gastaut syndrome (LGS) (add-on therapy)...
June 13, 2018: Neurology
https://www.readbyqxmd.com/read/29895363/low-dose-thimerosal-ethyl-mercury-is-still-used-in-infants-vaccines-should-we-be-concerned-with-this-form-of-exposure
#9
REVIEW
José G Dórea
In developing countries, Thimerosal-containing vaccines (TCV) are the main causes of organic Hg exposure for newborns, neonates, and infants immunized with TCV. This article addresses early-life exposure to this unique organic mercury compound (ethylmercury-EtHg) and the risks of its exposure. English language studies pertaining to Thimerosal/EtHg toxicity and exposure during early life were searched in PubMed; and, those publications judged to be relevant to the topic of this review were selected. The risk from the neurotoxic effects of pre- and post-natal Hg exposures depend, in part, on aggravating or attenuating environmental and/or genetic-associated factors...
September 2018: Journal of Trace Elements in Medicine and Biology
https://www.readbyqxmd.com/read/29894448/neurologic-outcomes-after-extracorporeal-membrane-oxygenation-a-systematic-review
#10
Katharine Boyle, Ryan Felling, Alvin Yiu, Wejdan Battarjee, Jamie McElrath Schwartz, Cynthia Salorio, Melania M Bembea
OBJECTIVES: The goal of this systematic review of the literature was to summarize neurologic outcomes following neonatal and pediatric extracorporeal membrane oxygenation. DATA SOURCES: We conducted electronic searches of PubMed, Scopus, Web of Science, CINAHL, Cochrane, and EMBASE. STUDY SELECTION: Inclusion criteria included publication dates 2000-2016, patient ages 0-18 years, and use of standardized measures to evaluate outcomes after extracorporeal membrane oxygenation...
June 11, 2018: Pediatric Critical Care Medicine
https://www.readbyqxmd.com/read/29891563/repeat-associated-non-atg-translation-in-neurological-diseases
#11
Tao Zu, Amrutha Pattamatta, Laura P W Ranum
More than 40 different neurological diseases are caused by microsatellite repeat expansions that locate within translated or untranslated gene regions, including 5' and 3' untranslated regions (UTRs), introns, and protein-coding regions. Expansion mutations are transcribed bidirectionally and have been shown to give rise to proteins, which are synthesized from three reading frames in the absence of an AUG initiation codon through a novel process called repeat-associated non-ATG (RAN) translation. RAN proteins, which were first described in spinocerebellar ataxia type 8 (SCA8) and myotonic dystrophy type 1 (DM1), have now been reported in a growing list of microsatellite expansion diseases...
June 11, 2018: Cold Spring Harbor Perspectives in Biology
https://www.readbyqxmd.com/read/29891101/-paraneoplastic-syndromes-in-ophthalmology-french-version-of-the-article
#12
REVIEW
A Bussat, S Langner-Lemercier, A Salmon, F Mouriaux
Paraneoplastic syndromes involving the visual system are a heterogeneous group of disorders occurring in the setting of systemic malignancy. Although these syndromes are rare, the clinical manifestations can herald an unsuspected, underlying malignancy. The associated antibodies and histopathology of each syndrome are presented to help in the understanding of these autoimmune phenomena. Outlined in this review article are diagnostic features useful in differentiating cancer-associated retinopathy, melanoma-associated retinopathy, paraneoplastic polymorphous vitelliform maculopathy, bilateral diffuse uveal melanocytic proliferation and paraneoplastic neurologic syndromes such as optic neuropathy, opsoclonus-myoclonus, Lambert-Eaton myasthenia and paraneoplastic cerebellar degeneration...
June 9, 2018: Journal Français D'ophtalmologie
https://www.readbyqxmd.com/read/29889115/the-fatigue-assessment-scale-quality-and-availability-in-sarcoidosis-and-other-diseases
#13
Celine Hendriks, Marjolein Drent, Marjon Elfferich, Jolanda De Vries
PURPOSE OF REVIEW: Fatigue is a problem experienced by many patients suffering from chronic diseases, including sarcoidosis patients. It has a substantial influence on patients' quality of life (QoL). It is, therefore, important to properly assess fatigue with a valid and reliable measure. The Fatigue Assessment Scale (FAS) is the only validated self-reporting instrument classifying fatigue in sarcoidosis. The aim of this review was to examine the psychometric properties of the FAS and the diseases and languages in which it has been used...
June 7, 2018: Current Opinion in Pulmonary Medicine
https://www.readbyqxmd.com/read/29888644/regulation-of-cytochrome-p450-gene-expression-by-ketamine-a-review
#14
Jui-Tai Chen, Li Wei, Ta-Liang Chen, Chun-Jen Huang, Ruei-Ming Chen
Although used as an anesthetic drug for decades, ketamine appears to have garnered renewed interest due to its potential therapeutic uses in pain therapy, neurology, and psychiatry. Ketamine undergoes extensive oxidative metabolism by cytochrome P450 (CYP) enzymes. Considerable efforts have been expended to elucidate the ketamine-induced regulation of CYP gene expression. The safety profile of chronic ketamine administration is still unclear. Understanding how ketamine regulates CYP gene expression is clinically meaningful...
June 10, 2018: Expert Opinion on Drug Metabolism & Toxicology
https://www.readbyqxmd.com/read/29888440/kawasaki-disease-shock-syndrome-a-unique-and-severe-subtype-of-kawasaki-disease
#15
Luisa Berenise Gamez-Gonzalez, Isabel Moribe-Quintero, Martin Cisneros-Castolo, Javier Varela-Ortiz, Mireya Muñoz-Ramírez, Martin Garrido-García, Marco Yamazaki-Nakashimada
BACKGROUND: Kawasaki disease shock syndrome (KDSS) is an uncommon presentation of Kawasaki disease (KD). KDSS has been associated with more severe markers of inflammation, coronary abnormalities and IVIG resistance. METHODS: A retrospective, descriptive study of children with KDSS in two hospitals was performed. Relevant articles about KD and shock were collected, demographic data, clinical presentation, laboratory variables, echocardiogram findings, treatment and special features were analyzed when available...
June 11, 2018: Pediatrics International: Official Journal of the Japan Pediatric Society
https://www.readbyqxmd.com/read/29888278/a-systematic-review-of-the-effects-of-hyperoxia-in-acutely-ill-patients-should-we-aim-for-less
#16
REVIEW
R Stolmeijer, H R Bouma, J G Zijlstra, A M Drost-de Klerck, J C Ter Maaten, J J M Ligtenberg
Introduction: Despite widespread and liberal use of oxygen supplementation, guidelines about rational use of oxygen are scarce. Recent data demonstrates that current protocols lead to hyperoxemia in the majority of the patients and most health care professionals are not aware of the negative effects of hyperoxemia. Method: To investigate the effects of hyperoxemia in acutely ill patients on clinically relevant outcomes, such as neurological and functional status as well as mortality, we performed a literature review using Medline (PubMed) and Embase...
2018: BioMed Research International
https://www.readbyqxmd.com/read/29886716/updates-on-prevention-of-cardioembolic-strokes
#17
Mehmet Akif Topcuoglu, Liping Liu, Dong-Eog Kim, M Edip Gurol
Cardiac embolism continues to be a leading etiology of ischemic strokes worldwide. Although pathologies that result in cardioembolism have not changed over the past decade, there have been significant advances in the treatment and stroke prevention methods for these conditions. Atrial fibrillation remains the prototypical cause of cardioembolic strokes. The availability of new long-term monitoring devices for atrial fibrillation detection such as insertable cardiac monitors has allowed accurate detection of this leading cause of cardioembolism...
May 2018: Journal of Stroke
https://www.readbyqxmd.com/read/29881220/sacral-chordoma-a-review-of-literature
#18
REVIEW
S Pillai, S Govender
Chordoma is a rare malignant tumor with predilection for the sacrum. A favorable outcome depends on early diagnosis and surgical excision with tumor free margins. Aim: To review the incidence and prevalence of sacral chordoma and the appropriate surgical management and formulate a criteria for early diagnosis. Materials and methods: Thirty eight articles on the subject of sacral chordoma and extrapolated data of clinical and surgical significance. Results: The commonest presenting feature in patients with sacral chordoma was lower back pain which was worse on sitting and up to a third of these patients had associated urinary tract infections, constipation or symptoms of disc herniation...
June 2018: Journal of Orthopaedics
https://www.readbyqxmd.com/read/29879772/combined-laminoplasty-and-posterior-fusion-for-cervical-spondylotic-myelopathy-treatment-a-literature-review
#19
Kelly J Bridges, Lauren N Simpson, Carli L Bullis, Andy Rekito, Christina M Sayama, Khoi D Than
STUDY DESIGN: A literature review. PURPOSE: To explore the utility of laminoplasty in combination with instrumented fusion, with a focus on neurological outcomes and changes in kyphotic deformity. OVERVIEW OF LITERATURE: Management of cervical spondylotic myelopathy (CSM) to reduce morbidity within the neurosurgical population. METHODS: A US National Library of Medicine PubMed search was conducted for manuscripts pertaining to cervical laminoplasty and fusion for the management of CSM...
June 2018: Asian Spine Journal
https://www.readbyqxmd.com/read/29879513/a-case-report-of-idiopathic-spinal-subdural-hematoma-and-literature-review
#20
Yongli Wang, Hua Zheng, Yafeng Ji, Qian Lu, Xiongfeng Li, Xue-Sheng Jiang
STUDY DESIGN: This article reported a case of idiopathic spinal subdural hematoma (SDH) and made a review of this disease. OBJECTIVE: To make a review of idiopathic spinal subdural hematoma. SUMMARY OF BACKGROUND DATA: To the best of our knowledge, there are 20 cases idiopathic SDH only 1 case which reported the idiopathic SDH located in cervical region. METHODS: A 43-year-old man had a sudden onset of needle-like and continuous neck pain for 3 days with paresthesias and paraplegia...
June 4, 2018: World Neurosurgery
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