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chronic musculoskeletal pain

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https://www.readbyqxmd.com/read/28919630/deep-vein-thrombosis-in-a-post-coronary-artery-bypass-grafting-patient-successful-conservative-management
#1
S H Sarker, A K Miraj, M A Hossain, M Aftabuddin
Deep vein thrombosis is an alarming medical emergency. Deep vein thrombosis or deep venous thrombosis (DVT) is the formation of a blood clot (thrombus) within a deep vein predominantly in the legs. Post-Coronary Artery Bypass Grafting deep vein thrombosis is a very rare medical condition relatively in Asian. Approximately 80% of deep vein thrombosis (DVTs) is clinically asymptomatic, 20% of those that actually demonstrate signs and symptoms can be easily confused with symptoms of other commonly presenting musculoskeletal disorders...
July 2017: Mymensingh Medical Journal: MMJ
https://www.readbyqxmd.com/read/28901422/association-between-endothelin%C3%A2-1-and-fibromyalgia-syndrome
#2
Seong-Su Nah, Hwayoung Lee, Yeongseon Hong, Jiyun Im, Hansol Won, Sung-Hae Chang, Hyung-Ki Kim, Jun-Tack Kwon, Hak-Jae Kim
Fibromyalgia syndrome (FMS) is characterized by widespread chronic musculoskeletal pain, stiffness and pressure hyperalgesia at soft tissue tender points. Patients with FMS may exhibit a tendency towards cold extremities and cold‑induced vasospasm. Endothelin‑1 (EDN1) is a potent vasoconstrictor that is mainly produced by endothelial cells. The present study aimed to determine whether plasma expression levels avvnd single‑nucleotide polymorphism (SNP; rs1800541) of the EDN1 gene were associated with FMS and/or any of its clinical variables...
August 29, 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/28898137/pain-related-fear-and-its-disabling-impact-in-hypermobile-adolescents-with-chronic-musculoskeletal-pain
#3
Thijs van Meulenbroek, Ivan P J Huijnen, Carlijn M H Wiertz, Jeanine A Verbunt
Study Design Cross-sectional study. Background Chronic musculoskeletal pain (CMP) has a negative impact on physical functioning. During adolescence joint hypermobility is a potential risk factor for developing CMP and pain-related fear contributes to the persistence of CMP. Whether pain-related fear and being hypermobile are related and even reinforce each other, resulting in a stronger association with perceived level of disability, is still unknown. Objectives To evaluate whether pain-related fear has a stronger association with disability in hypermobile compared to non-hypermobile adolescents with CMP...
September 12, 2017: Journal of Orthopaedic and Sports Physical Therapy
https://www.readbyqxmd.com/read/28894792/influence-of-hla-matching-on-the-efficacy-of-allogeneic-mesenchymal-stromal-cell-therapies-for-osteoarthritis-and-degenerative-disc-disease
#4
Javier García-Sancho, Ana Sánchez, Aurelio Vega, David C Noriega, Mercedes Nocito
BACKGROUND: The necessity for more effective therapies for chronic osteoarticular diseases has led to the development of treatments based on mesenchymal stem cells (MSCs), the natural precursors of musculoskeletal tissue. Treatments with autologous MSCs yielded excellent results, with nearly 70% improvement of pain and disability in osteoarthritis and degenerative disc disease. Using allogeneic MSCs is logistically more convenient and would widen the pool of eligible patients, but potential immune rejection should be considered...
September 2017: Transplantation Direct
https://www.readbyqxmd.com/read/28894385/genetic-and-epigenetic-epidemiology-of-chronic-widespread-pain
#5
REVIEW
Jasmine I Kerr, Andrea Burri
The etiology underlying chronic widespread pain (CWP) remains largely unknown. An integrative biopsychosocial model seems to yield the most promising explanations for the pathogenesis of the condition, with genetic factors also contributing to disease development and maintenance. Here, we conducted a search of studies investigating the genetic and epigenetic epidemiology of CWP through electronic databases including Web of Science, Medline, PubMed, EMBASE, and Google Scholar. Combinations of keywords including CWP, chronic pain, musculoskeletal pain, genetics, epigenetics, gene, twins, single-nucleotide polymorphism, genotype, and alleles were used...
2017: Journal of Pain Research
https://www.readbyqxmd.com/read/28893757/effectiveness-and-cost-effectiveness-of-duloxetine-added-to-usual-care-for-patients-with-chronic-pain-due-to-hip-or-knee-osteoarthritis-protocol-of-a-pragmatic-open-label-cluster-randomised-trial-the-duo-trial
#6
Jacoline J van den Driest, Dieuwke Schiphof, Pim A J Luijsterburg, Aafke R Koffeman, Marc A Koopmanschap, Patrick J E Bindels, Sita M A Bierma-Zeinstra
INTRODUCTION: Osteoarthritis (OA) is a highly prevalent painful condition of the musculoskeletal system. The effectiveness of current analgesic options has proven to be limited and improved analgesic treatment is needed. Several randomised placebo-controlled trials have now demonstrated the efficacy of duloxetine, an antidepressant with a centrally acting effect, in the treatment of OA pain. The aim of the current study is to investigate if duloxetine is effective and cost-effective as a third-choice analgesic added to usual care for treating chronic pain compared with usual care alone in general practice...
September 11, 2017: BMJ Open
https://www.readbyqxmd.com/read/28890282/opioid-dosing-trends-over-eight-years-among-us-veterans-with-musculoskeletal-disorders-after-returning-from-service-in-support-of%C3%A2-recent-conflicts
#7
Ling Han, Heather Allore, Joseph Goulet, Harini Bathulapali, Melissa Skanderson, Cynthia Brandt, Sally Haskell, Erin Krebs
PURPOSE: To examine long-term opioid dosing trends among Veterans with chronic pain. METHODS: We identified 79,015 Veterans with musculoskeletal disorders who were dispensed greater than or equal to 1 opioid prescriptions between 2002 and 2009 after returning from recent conflicts. Opioid-dosing trends were examined using a generalized estimating equation while accounting for patient characteristics, temporal and geographic confounding. RESULTS: In total, 472,819 opioid prescriptions were dispensed (mean ± standard deviation: 6...
August 24, 2017: Annals of Epidemiology
https://www.readbyqxmd.com/read/28887786/assessing-psycho-social-barriers-to-rehabilitation-in-injured-workers-with-chronic-musculoskeletal-pain-development-and-item-properties-of-the-yellow-flag-questionnaire-yfq
#8
Cornelia Rolli Salathé, Maurizio Alen Trippolini, Livio Claudio Terribilini, Michael Oliveri, Achim Elfering
Purpose To develop a multidimensional scale to asses psychosocial beliefs-the Yellow Flag Questionnaire (YFQ)-aimed at guiding interventions for workers with chronic musculoskeletal (MSK) pain. Methods Phase 1 consisted of item selection based on literature search, item development and expert consensus rounds. In phase 2, items were reduced with calculating a quality-score per item, using structure equation modeling and confirmatory factor analysis on data from 666 workers. In phase 3, Cronbach's α, and Pearson correlations coefficients were computed to compare YFQ with disability, anxiety, depression and self-efficacy and the YFQ score based on data from 253 injured workers...
September 8, 2017: Journal of Occupational Rehabilitation
https://www.readbyqxmd.com/read/28884562/%C3%A3-mpsq-short-score-and-determinants-of-chronic-pain-cross-sectional-results-from-a-middle-aged-birth-cohort
#9
Olli Ruokolainen, Juha Auvinen, Steven J Linton, Sauli Herrala, Pasi Eskola, Markus Paananen, Raija Korpelainen, Jaro Karppinen
BACKGROUND: The Örebro Musculoskeletal Pain Screening Questionnaire (ÖMPSQ) was developed to identify patients at risk of developing work disability due to pain. So far, neither the ÖMPSQ nor its short version (ÖMSPQ-short) have been tested in population-based samples. AIM: We examined the associations between several well-known determinants for chronic pain and ÖMPSQ-short score. DESIGN: Cross-sectional study. SETTING: All measurements and tests were made at the University of Oulu...
September 7, 2017: European Journal of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/28878418/effect-of-acupuncture-on-pain-and-quality-of-life-in-canine-neurological-and-musculoskeletal-diseases
#10
Nuno E O F Silva, Stelio P L Luna, Jean G F Joaquim, Heloisa D Coutinho, Fábio S Possebon
This prospective study investigated the effects of acupuncture alone or combined with analgesics in chronic pain and quality of life assessed by owners for up to 24 weeks in 181 dogs with neurological and musculoskeletal diseases. The scores before and after the onset of treatment were evaluated using the Wilcoxon test and the evolution of success was evaluated by Kaplan-Meier curves. Differences were considered significant at P < 0.05. The success rates for Helsinki chronic pain index (HCPI), quality of life assessment, and visual analog scales (VAS) for pain and locomotion were 79%, 84%, 78%, and 78% of the animals, respectively, when both diseases and groups of treatment were combined...
September 2017: Canadian Veterinary Journal. la Revue Vétérinaire Canadienne
https://www.readbyqxmd.com/read/28877142/adding-prefrontal-transcranial-direct-current-stimulation-before-occipital-nerve-stimulation-in-fibromyalgia
#11
Hye Bin Yoo, Jan Ost, Wim Joos, Tony Van Havenbergh, Dirk De Ridder, Sven Vanneste
OBJECTIVES: Fibromyalgia is a type of chronic musculoskeletal pain without a clear peripheral origin of nociception, often associated with depression. The underlying pathophysiology involves changes in a functional network that is related to pain and emotional processing in the central nervous system. Transcranial direct current stimulation (tDCS) targeting the dorsolateral prefrontal cortex or the occipital nerve (ON) are non-invasive neuromodulation techniques capable of improving fibromyalgia symptoms...
September 1, 2017: Clinical Journal of Pain
https://www.readbyqxmd.com/read/28874969/cross-cultural-adaptation-validity-and-reliability-of-the-persian-version-of-the-orebro-musculoskeletal-pain-screening-questionnaire
#12
Asrin Shafeei, Hamid Reza Mokhtarinia, Azam Maleki-Ghahfarokhi, Leila Piri
STUDY DESIGN: Observational study. PURPOSE: To cross-culturally translate the Orebro Musculoskeletal Pain Screening Questionnaire (OMPQ) into Persian and then evaluate its psychometric properties (reliability, validity, ceiling, and flooring effects). OVERVIEW OF LITERATURE: To the authors' knowledge, prior to this study there has been no validated instrument to screen the risk of chronicity in Persian-speaking patients with low back pain (LBP) in Iran...
August 2017: Asian Spine Journal
https://www.readbyqxmd.com/read/28860397/diagnosis-of-prosthetic-joint-infection-with-alpha-defensin-using-a-lateral-flow-device-a-multicentre-study
#13
MULTICENTER STUDY
P Berger, M Van Cauter, R Driesen, J Neyt, O Cornu, J Bellemans
AIMS: The purpose of this current multicentre study is to analyse the presence of alpha-defensin proteins in synovial fluid using the Synovasure lateral flow device and to determine its diagnostic reliability and accuracy compared with the prosthetic joint infection (PJI) criteria produced by the Musculoskeletal Infection Society (MSIS). PATIENTS AND METHODS: A cohort of 121 patients comprising 85 total knee arthroplasties and 36 total hip arthroplasties was prospectively evaluated between May 2015 and June 2016 in three different orthopaedic centres...
September 2017: Bone & Joint Journal
https://www.readbyqxmd.com/read/28859685/an-umbrella-review-of-the-literature-on-the-effectiveness-of-psychological-interventions-for-pain-reduction
#14
Georgios Markozannes, Eleni Aretouli, Evangelia Rintou, Elena Dragioti, Dimitrios Damigos, Evangelia Ntzani, Evangelos Evangelou, Konstantinos K Tsilidis
BACKGROUND: Psychological interventions are widely implemented for pain management and treatment, but their reported effectiveness shows considerable variation and there is elevated likelihood for bias. METHODS: We summarized the strength of evidence and extent of potential biases in the published literature of psychological interventions for pain treatment using a range of criteria, including the statistical significance of the random effects summary estimate and of the largest study of each meta-analysis, number of participants, 95% prediction intervals, between-study heterogeneity, small-study effects and excess significance bias...
August 31, 2017: BMC Psychology
https://www.readbyqxmd.com/read/28859589/predicting-low-back-pain-outcomes-suggestions-for-future-directions
#15
Jeff Boissoneault, Jennifer Mundt, Michael Robinson, Steven Z George
Chronic low back pain (LBP) is a common and costly musculoskeletal pain condition, and effective treatment of LBP represents a significant goal of physical therapists. Establishing a targeted track of treatment for patients with LBP at high risk for chronicity that is focused on modifiable prognostic factors could have significant personal and societal benefit. Such an approach would require that clinicians accurately predict the patients who are at an elevated risk of developing chronic LBP in the early stages of the condition...
September 2017: Journal of Orthopaedic and Sports Physical Therapy
https://www.readbyqxmd.com/read/28844618/impact-of-pain-and-pain-subtypes-on-the-quality-of-life-of-patients-with-parkinson-s-disease
#16
Seong-Min Choi, Byeong C Kim, Hyun-Jung Jung, Geum-Jin Yoon, Kyung Wook Kang, Kang-Ho Choi, Joon-Tae Kim, Seung-Han Lee, Man-Seok Park, Myeong-Kyu Kim, Ki-Hyun Cho
Pain is a frequent and troublesome non-motor symptom of Parkinson's disease (PD) and has a negative impact on quality of life (QoL). The aim of this study was to investigate the relative impact of pain or a specific pain subtype on the QoL of patients with PD. We included 161 patients with PD. Pain was assessed using the patients' descriptions, a structured interview, and a detailed neurological examination. QoL was assessed using the 39-item Parkinson's Disease Questionnaire (PDQ-39). One hundred and twenty (74...
August 24, 2017: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/28842760/prevalence-of-vitamin-d-deficiency-in-chronic-and-subacute-low-back-pain-patients-in-india-a-triple-arm-controlled-study
#17
Ajay Panwar, Chandrasekhar Valupadas, Madhavarao Veeramalla, Hunsur N Vishwas
Vitamin D is vital for musculoskeletal health and may be associated with subacute and chronic low back pain. The objective of this study was to estimate the prevalence of vitamin D deficiency among chronic low back pain (CLBP) and subacute low back pain (SLBP), and compare the same with healthy controls. This study was designed as triple-arm case-control study comprising of CLBP, SLBP, and controls. SLBP and CLBP cases were consecutively enrolled over 3 months of winter season from November 2016 to January 2017...
August 25, 2017: Clinical Rheumatology
https://www.readbyqxmd.com/read/28833988/beyond-weakness-characterization-of-pain-sensory-profile-and-conditioned-pain-modulation-in-patients-with-motor-neuron-disease-a-controlled-study
#18
L C G Lopes, R Galhardoni, V Silva, F M H Jorge, L T Yeng, D Callegaro, G Chadi, M J Teixeira, D Ciampi de Andrade
BACKGROUND: Motor neuron diseases (MND) represent a group of disorders that evolve with inexorable muscle weakness and medical management is based on symptom control. However, deeper characterization of non-motor symptoms in these patients have been rarely reported. METHODS: This cross-sectional study aimed to describe non-motor symptoms in MND and their impact on quality of life and functional status, with a focus on pain and sensory changes. Eighty patients (31 females, 55...
August 22, 2017: European Journal of Pain: EJP
https://www.readbyqxmd.com/read/28832612/neck-shoulder-discomfort-due-to-visually-demanding-experimental-near-work-is-influenced-by-previous-neck-pain-task-duration-astigmatism-internal-eye-discomfort-and-accommodation
#19
Camilla Zetterberg, Mikael Forsman, Hans O Richter
Visually demanding near work can cause eye discomfort, and eye and neck/shoulder discomfort during, e.g., computer work are associated. To investigate direct effects of experimental near work on eye and neck/shoulder discomfort, 33 individuals with chronic neck pain and 33 healthy control subjects performed a visual task four times using four different trial lenses (referred to as four different viewing conditions), and they rated eye and neck/shoulder discomfort at baseline and after each task. Since symptoms of eye discomfort may differ depending on the underlying cause, two categories were used; internal eye discomfort, such as ache and strain, that may be caused by accommodative or vergence stress; and external eye discomfort, such as burning and smarting, that may be caused by dry-eye disorders...
2017: PloS One
https://www.readbyqxmd.com/read/28832199/acute-calcific-tendinitis-of-the-index-finger-in-a-child
#20
Frances M Walocko, Ian C Sando, Steven C Haase, Jeffrey H Kozlow
BACKGROUND: Calcific tendinitis is characterized by calcium hydroxyapatite crystal deposition within tendons and is a common cause of musculoskeletal pain in adults. Its clinical manifestations may be acute, chronic, or asymptomatic. Acute calcific tendinitis is self-resolving condition that is rarely reported in the pediatric population and may be overlooked for more common processes, leading to unnecessary treatment. METHODS: A chart reivew was performed of a single case of acute calcific tendonitis of the index finger in a child...
September 2017: Hand: Official Journal of the American Association for Hand Surgery
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