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https://www.readbyqxmd.com/read/29029350/the-british-society-for-rheumatology-guideline-for-the-management-of-systemic-lupus-erythematosus-in-adults
#1
Caroline Gordon, Maame-Boatemaa Amissah-Arthur, Mary Gayed, Sue Brown, Ian N Bruce, David D'Cruz, Benjamin Empson, Bridget Griffiths, David Jayne, Munther Khamashta, Liz Lightstone, Peter Norton, Yvonne Norton, Karen Schreiber, David Isenberg
No abstract text is available yet for this article.
October 6, 2017: Rheumatology
https://www.readbyqxmd.com/read/29029296/the-british-society-for-rheumatology-guideline-for-the-management-of-systemic-lupus-erythematosus-in-adults-executive-summary
#2
Caroline Gordon, Maame-Boatemaa Amissah-Arthur, Mary Gayed, Sue Brown, Ian N Bruce, David D'Cruz, Benjamin Empson, Bridget Griffiths, David Jayne, Munther Khamashta, Liz Lightstone, Peter Norton, Yvonne Norton, Karen Schreiber, David Isenberg
No abstract text is available yet for this article.
October 6, 2017: Rheumatology
https://www.readbyqxmd.com/read/29016895/the-accuracy-of-a-fibromyalgia-diagnosis-in-general-practice
#3
Rosalind Gittins, Molly Howard, Ameer Ghodke, Timothy J Ives, Paul Chelminski
Objective: To compare the characteristics of people with fibromyalgia (FM) with those with other forms of nonmalignant chronic pain. Design: A prospective cohort study conducted in a chronic pain management clinic within an academic medical center. Setting. : Many symptoms of the chronic pain syndrome FM are common to other pain or musculoskeletal syndromes. FM may be misdiagnosed by clinicians. Subjects: Thirty-three patients with a working diagnosis of FM were identified: 26 (78...
July 17, 2017: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
https://www.readbyqxmd.com/read/28957572/the-british-society-for-rheumatology-guideline-for-the-management-of-adults-with-primary-sj%C3%A3-gren-s-syndrome
#4
Elizabeth J Price, Saaeha Rauz, Anwar R Tappuni, Nurhan Sutcliffe, Katie L Hackett, Francesca Barone, Guido Granata, Wan-Fai Ng, Benjamin A Fisher, Michele Bombardieri, Elisa Astorri, Ben Empson, Genevieve Larkin, Bridget Crampton, Simon J Bowman
No abstract text is available yet for this article.
October 1, 2017: Rheumatology
https://www.readbyqxmd.com/read/28957550/the-british-society-for-rheumatology-guideline-for-the-management-of-adults-with-primary-sj%C3%A3-gren-s-syndrome
#5
Elizabeth J Price, Saaeha Rauz, Anwar R Tappuni, Nurhan Sutcliffe, Katie L Hackett, Francesca Barone, Guido Granata, Wan-Fai Ng, Benjamin A Fisher, Michele Bombardieri, Elisa Astorri, Ben Empson, Genevieve Larkin, Bridget Crampton, Simon J Bowman
No abstract text is available yet for this article.
October 1, 2017: Rheumatology
https://www.readbyqxmd.com/read/28957549/the-british-society-for-rheumatology-guideline-for-the-management-of-adults-with-primary-sj%C3%A3-gren-s-syndrome
#6
Elizabeth J Price, Saaeha Rauz, Anwar R Tappuni, Nurhan Sutcliffe, Katie L Hackett, Francesca Barone, Guido Granata, Wan-Fai Ng, Benjamin A Fisher, Michele Bombardieri, Elisa Astorri, Ben Empson, Genevieve Larkin, Bridget Crampton, Simon J Bowman
No abstract text is available yet for this article.
October 1, 2017: Rheumatology
https://www.readbyqxmd.com/read/28955489/mortality-in-patients-with-interstitial-lung-disease-treated-with-rituximab-or-tnfi-as-a-first-biologic
#7
Katie L Druce, Kundan Iqbal, Kath D Watson, Deborah P M Symmons, Kimme L Hyrich, Clive Kelly
OBJECTIVES: Guidelines cautioned prescribing of tumour necrosis factor inhibitors (TNFi) to patients with rheumatoid arthritis and interstitial lung disease (RA-ILD) after reports of new or worsening of ILD. Less is known about outcomes among patients with RA-ILD who receive rituximab (RTX). This study compares mortality in patients with RA-ILD who received RTX or TNFi as their first biologic. METHODS: Participants with RA-ILD recruited to the British Society for Rheumatology Biologics Register for RA were included...
2017: RMD Open
https://www.readbyqxmd.com/read/28943980/physician-pharmacist-agreement-about-off-label-use-of-medications-in-private-clinical-settings-in-baghdad-iraq
#8
Saad A Hussain, Ashwaq N Abbas, Hasan A Alhadad, Ali A Al-Jumaili, Zainab S Abdulrahman
OBJECTIVE: 1) To evaluate the relationship between physician-pharmacist agreement about the off-label drug use and 2) and to identify the most common off-label medication category/indications and prescriber clinical disciplines in private settings in Baghdad area, Iraq. METHODS: This study evaluated 980 off-label use requests in the private clinical settings within Baghdad area, Iraq from October 2013 to September 2015. The efficacy, safety, and convenience of each drug request and its alternative options were evaluated according to the patient health and demographic characteristics and standard guidelines...
July 2017: Pharmacy Practice
https://www.readbyqxmd.com/read/28941179/2017-american-college-of-rheumatology-guideline-for-the-prevention-and-treatment-of-glucocorticoid-induced-osteoporosis
#9
Lenore Buckley, Gordon Guyatt, Howard Fink, Timothy McAlindon
The Voting Panel recommended oral bisphosphonates as a first choice and parenteral bisphosphonates as a second choice after comparing data about absolute fracture reduction, harms (toxicity and inconvenience of daily injections), and costs. Drs. Maricic, Deal, Dore, and Laster cite the randomized trial of alendronate versus teriparatide in glucocorticoid-treated patients that reported incident fractures as a secondary outcome. This trial found a lower risk of clinical vertebral fractures in the teriparatide compared to alendronate treated patients (0% vs...
September 21, 2017: Arthritis Care & Research
https://www.readbyqxmd.com/read/28941168/comment-on-2017-american-college-of-rheumatology-guideline-for-the-prevention-and-treatment-of-glucocorticoid-induced-osteoporosis
#10
Michael Maricic, Chad Deal, Robin Dore, Andrew Laster
We have read the recently published 2017 American College of Rheumatology Guideline for the Prevention and Treatment of Glucocorticoid-Induced Osteoporosis (1), and applaud the committee's efforts, but have a number of areas of disagreement. Our main concern is that in adults at high risk for fracture, oral and then parenteral bisphosphonates are recommended over teriparatide in selecting drug therapy. This represents a departure from the 2010 ACR GIO Guidelines (2) which avoided rating bisphosphonates (either oral or parenteral) preferentially over teriparatide...
September 21, 2017: Arthritis Care & Research
https://www.readbyqxmd.com/read/28934978/adaptation-of-the-2015-american-college-of-rheumatology-treatment-guideline-for-rheumatoid-arthritis-for-the-eastern-mediterranean-region-an-exemplar-of-the-grade-adolopment
#11
Andrea Darzi, Manale Harfouche, Thurayya Arayssi, Samar Alemadi, Khaled A Alnaqbi, Humeira Badsha, Farida Al Balushi, Bassel Elzorkany, Hussein Halabi, Mohammed Hamoudeh, Wissam Hazer, Basel Masri, Mohammed A Omair, Imad Uthman, Nelly Ziade, Jasvinder A Singh, Robin Christiansen, Peter Tugwell, Holger J Schünemann, Elie A Akl
BACKGROUND: It has been hypothesized that adaptation of health practice guidelines to the local setting is expected to improve their uptake and implementation while cutting on required resources. We recently adapted the published American College of Rheumatology (ACR) Rheumatoid Arthritis (RA) treatment guideline to the Eastern Mediterranean Region (EMR). The objective of this paper is to describe the process used for the adaptation of the 2015 ACR guideline on the treatment of RA for the EMR...
September 21, 2017: Health and Quality of Life Outcomes
https://www.readbyqxmd.com/read/28932193/safety-profile-of-anticancer-and-immune-modulating-biotech-drugs-used-in-a-real-world-setting-in-campania-region-italy-bio-cam-observational-study
#12
Cristina Scavone, Liberata Sportiello, Maria G Sullo, Carmen Ferrajolo, Rosanna Ruggiero, Maurizio Sessa, Pasquale M Berrino, Gabriella di Mauro, Liberato Berrino, Francesco Rossi, Concetta Rafaniello, Annalisa Capuano
Objectives: To investigate the occurrence of adverse events (AEs) in naïve patients receiving biotech drugs. Design: A prospective observational study. Setting: Onco-hematology, Hepato-gastroenterology, Rheumatology, Dermatology, and Neurology Units in Campania Region (Italy). Participants: 775 patients (53.81% female) with mean age 56.0 (SD 15.2). The mean follow-up/patient was 3.48 (95% confidence interval 3.13-3.84). Main outcome measures: We collected all AEs associated to biotech drugs, including serious infections and malignancies...
2017: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/28903543/biosimilars-in-rheumatology-a-review-of-the-evidence-and-their-place-in-the-treatment-algorithm
#13
REVIEW
Hendrik Schulze-Koops, Alla Skapenko
Determining biosimilarity involves a comprehensive exercise with a focus on determining the comparability of the molecular characteristics and preclinical profile of the biosimilar and reference product, such that there is less need for extensive clinical testing to assure comparability of clinical outcomes. Three anti-TNF biosimilar agents are approved for patients with rheumatic diseases in the European Union. The infliximab (Remicade®) biosimilars CT-P13 (Remsima® and Inflectra®) and SB2 (Flixabi®) and the etanercept (Enbrel®) biosimilar SB4 (Benepali®) have shown close comparability to their reference medicinal products, having undergone extensive evaluations...
August 1, 2017: Rheumatology
https://www.readbyqxmd.com/read/28895297/changing-trends-in-therapeutic-plasmapheresis-an-indian-perspective
#14
Aseem K Tiwari, Gunjan Bhardwaj, Geet Aggarwal, Dinesh Arora, Ravi C Dara, Devi P Acharya, Sangeetha Gayam, Jui Choudhuri
Indications for therapeutic apheresis (TA) are dynamic; they keep changing and expanding because of introduction of newer treatment modalities and accumulating evidence in the form of case-reports, case-series and original articles. We evaluated our therapeutic plasmapheresis (TP) data and compared this data with an earlier published Indian report for indications, frequency, response rate and adverse reactions. We conducted a retrospective analysis of all TP procedures performed from January 2014 to June 2016 in department of Transfusion Medicine at a tertiary care hospital...
October 2017: Therapeutic Apheresis and Dialysis
https://www.readbyqxmd.com/read/28891365/gout-in-a-rheumatology-clinic-results-of-eular-acr-guidelines-compliant-treatment
#15
O Slot
OBJECTIVE: Surveys of treatment results of gout in primary care have shown that less than 25% of patients reach the recommended treatment target (serum urate < 0.36 mmol/l). The aim of this study was to measure the results of a specialized European League Against Rheumatism/American College of Rheumatology (EULAR/ACR) guidelines-based treatment of gout in a rheumatology clinic. METHOD: Data from consecutive new crystal-proven gout patients were analysed in a prospective observational study...
September 11, 2017: Scandinavian Journal of Rheumatology
https://www.readbyqxmd.com/read/28865482/decrease-in-bone-mineral-density-during-three-months-after-diagnosis-of-early-rheumatoid-arthritis-measured-by-digital-x-ray-radiogrammetry-predicts-radiographic-joint-damage-after-one-year
#16
Michael Ziegelasch, Kristina Forslind, Thomas Skogh, Katrine Riklund, Alf Kastbom, Ewa Berglin
BACKGROUND: Periarticular osteopenia is an early sign of incipient joint injury in rheumatoid arthritis (RA), but cannot be accurately quantified using conventional radiography. Digital X-ray radiogrammetry (DXR) is a computerized technique to estimate bone mineral density (BMD) from hand radiographs. The aim of this study was to evaluate whether decrease in BMD of the hands (BMD loss), as determined by DXR 3 months after diagnosis, predicts radiographic joint damage after 1 and 2 years in patients with early RA...
September 2, 2017: Arthritis Research & Therapy
https://www.readbyqxmd.com/read/28864376/methotrexate-hepatotoxicity-and-the-impact-of-nonalcoholic-fatty-liver-disease
#17
REVIEW
Akshay Shetty, WonKyung Cho, William Alazawi, Wing-Kin Syn
Methotrexate (MTX) is commonly used to treat individuals with rheumatological and dermatologic disorders. Current American College of Rheumatology (ACR) and American Association of Dermatology (AAD) guidelines identify diabetes and obesity as risk factors for MTX-induced liver injury. Both diabetes and obesity are components of the metabolic syndrome, and are also risk factors for nonalcoholic fatty liver disease (NAFLD). NAFLD affects approximately 40% of the U.S. population, and those with more advanced NAFLD (i...
August 2017: American Journal of the Medical Sciences
https://www.readbyqxmd.com/read/28852832/down-titration-of-biologics-for-the-treatment-of-rheumatoid-arthritis-a-systematic-literature-review
#18
Chak Sing Lau, Allan Gibofsky, Nemanja Damjanov, Sadiq Lula, Lisa Marshall, Heather Jones, Paul Emery
Biologic therapies have improved the management of rheumatoid arthritis (RA) and the treat-to-target approach has resulted in many patients achieving remission. In the current treatment landscape, clinicians have begun considering dose reduction/tapering for their patients. Rheumatology guidelines in Asia, Europe, and the United States include down-titration of biologics but admit that the level of evidence is moderate. We conducted a systematic literature review to assess the published studies that evaluate down-titration of biologics in RA...
August 29, 2017: Rheumatology International
https://www.readbyqxmd.com/read/28838768/brazilian-guidelines-for-the-diagnosis-and-treatment-of-postmenopausal-osteoporosis
#19
Sebastião Cézar Radominski, Wanderley Bernardo, Ana Patrícia de Paula, Ben-Hur Albergaria, Caio Moreira, Cesar Eduardo Fernandes, Charlles H M Castro, Cristiano Augusto de Freitas Zerbini, Diogo S Domiciano, Laura M C Mendonça, Luciano de Melo Pompei, Mailze Campos Bezerra, Marco Antônio R Loures, Maria Celeste Osório Wender, Marise Lazaretti-Castro, Rosa M R Pereira, Sergio Setsuo Maeda, Vera Lúcia Szejnfeld, Victoria Z C Borba
Osteoporosis is the leading cause of fractures in the population older than 50 years. This silent disease affects primarily postmenopausal women and the elderly, and the morbidity and mortality rates are high. The main goal of treating osteoporosis is the prevention of fractures. The identification of populations at risk through early diagnosis and treatment is essential. The last Brazilian guideline for the treatment of postmenopausal osteoporosis was elaborated in 2002. Since then, new strategies for diagnosis and risk stratification have been developed, and drugs with novel action mechanisms have been added to the therapeutic arsenal...
2017: Revista Brasileira de Reumatologia
https://www.readbyqxmd.com/read/28838753/we-commend-the-effort-2017-american-college-of-rheumatology-american-association-of-hip-and-knee-surgeons-guideline-for-the-perioperative-management-of-antirheumatic-medication-in-patients-with-rheumatic-diseases-undergoing-elective-total-hip-or-total-knee
#20
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